
Hosted by Stago · EN
Ask Stago is the podcast for Hemostasis laboratory professionals.
In less than 10 minutes, Lisa Gannon and Anne-Cécile Ortega host special guests to provide “expert answers to your expert questions”. Stay abreast of hot topics in Hemostasis through Ask Stago! Contribute to the discussion by sending your questions to ask@stago.com
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation. In today’s episode, our guest Doctor Isabelle Gouin-Thibault will discuss the influence of dextran sulfate in anti-Xa assay. Literature sources: Lasne, D. et al. (2023) Factors Influencing Anti-Xa Assays: A Multicenter Prospective Study in Critically Ill and Noncritically Ill Patients Receiving Unfractionated Heparin. Thrombosis and Haemostasis, 123 (12), 1105. Hardy, M. et al. (2023) Reassessment of dextran sulfate in anti-Xa assay for unfractionated heparin laboratory monitoring. Res Pract Thromb Haemost. 7 (8), 102257 Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In this “back to basics” mini-series, Dr LaShanta Brice will discuss the clinical utility of the three most common parameters tested in the lab, the PT, APTT and Fibrinogen.Today we are going to cover the Prothrombin Time!We will discover why an order for a PT would be received by the lab, generally why the PT is used in practice and some emerging trends particularly when considering the INR clinic.Happy listening!Literature source: CLSI H47 One-Stage Prothrombin Time (PT) Test and Activated Partial Thromboplastin Time (APTT) Test Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.In today’s episode, Emily Pullen, North America Product Manager, will tell us more about Stago solution to improve lab productivity with the STA Workcell Max.Literature sources:https://www.stago.com/products-services/max-generation-analysers/sta-workcell-max/76f0f5a022edbacbce5ceea5f072e0c4 Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In today’s episode, our guest Dr. Refaai will help us understand the formation and function of fibrin monomers (FM) in hemostasis, highlighting their crucial role in coagulation and clot formation and the need for more prospective studies to validate this assay for clinical indications such as DIC, VTE and cancer.Literature sources:Refaai M.A. (2018) The Clinical Significance of Fibrin Monomers. Thromb Haemost, 118, 1856.Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today’s episode, Anne-Cécile Ortega will further explain what a MyOptiLab audit is — a service offered by Stago that involves a comprehensive workflow study using the Lean Six Sigma methodology. This audit is designed to help laboratories enhance their efficiency by identifying areas for improvement and optimizing processes. Literature sources:Bhat, R., & Wagh, P. (2013). "Application of Six Sigma methodology in clinical diagnostic laboratories: A case study." International Journal of Scientific and Research Publications*, 3(7), 1-6. Goh, T. N., & Ang, K. S. (2011). "The application of Lean Six Sigma in healthcare." International Journal of Quality & Reliability Management*, 28(6), 548-564. Sundararajan, V., & Sharma, P. (2012). "Lean Six Sigma in the clinical laboratory: Achieving improvement in laboratory processes." Clinical Laboratory Management Review*, 26(2), 82-89. Kendall, J., & Jones, D. (2017). "The role of Lean Six Sigma in clinical laboratory testing." American Journal of Clinical Pathology*, 147(3), 298-305. Sofiya, L., & Mirza, M. (2014). "Enhancing diagnostic laboratory performance through Lean Six Sigma." Journal of Healthcare Engineering*, 2014, Article ID 870376, 10 pages. Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In today’s episode, Karine Carrière will explain further what are microvesicles, their importance in coagulation and how to analyze them. Literature sources:[Tesselaar et al.], [Lacroix et al.] [Faille et al.] [Mullier et al.] Vallier et al.] . [Nieuwland et al.]Kim HK, Song KS, Park YS, Kang YH, Lw YJ, Lw KR, et al.Elevated levels of circulating platelet microparticles, VEGF, 11-6 andFiANTES in patients Wlth gastrlc cancer. possible mle of a metastasispredlotor. Eur J Cancer 2003;39(2):184-91.Helley D, Banu E, Bouziane A, Banu A, Scotte F, Fiher AM, et al. Platelet microparticles: a potential predictive factor of survival in hormone-reac pmstate cancer patients treated with docetaxel-based chemotherapy. Eur Urnl2009;56(3):479-84.Zwicker JI, Liebman HA, Neuberg D, Lecmix R, Bauer KA, Furie BC, et ai. Tmr-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res 2009; 15 (22): 68630-40 Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.This month we meet Joseph Bautista, is a 37 year old US man living with a rare clotting disorder, a Factor XI deficiency otherwise known as Hemophilia C. His journey so far has not been an easy one but by educating himself and advocating for the best care he is living a full and healthy life working as a data architect in the IT sector. Its an inspiring and reassuring story for anyone facing a rare bleeding disorder diagnosis & proves the importance of patient empowerment. Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In today’s episode, our guest Evelyne Escarmant will help us to understand what is behind the recent update of ISO 15189 and what it means for us as manufacturers and indeed the clinical laboratoryLiterature sources: ISO 15189; Medical laboratories – Requirements for quality and competence Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In today’s episode, our guest Florence Crépet will help us to understand what is behind the wording “limit of blank”, “limit of detection” and “limit of quantification”, and what it means for the clinical laboratoryLiterature sources:Armbruster DA, Pry T. Limit of blank, limit of detection and limit of quantitation. Clin Biochem Rev. 2008 Aug;29 Suppl 1(Suppl 1):S49-52.CLSI. Evaluation of Detection Capability for Clinical Laboratory Measurement Procedures; Approved Guideline—Second Edition. CLSI document EP17-A2. Wayne, PA: Clinical and Laboratory Standards Institute; 2012.CLSI Evaluation of Detection Capability Implementation Guide. CLSI Document EP17-Ed2-IG. Wayne, PA: Clinical and Laboratory Standards Institute; 2021. Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.In this episode, to coincide with International Womens Day (March 8th), we are focusing on Gender equality in the workforce, why this is good for business and good for society overall. We meet with Eva Ohlsson Desormonts, Group HR Director for Stago and Amandine Serret International Business Support and Communications Director for Stago as well as an Executive Coach.Literature sources:Women in the Workpace 2022, McKinsey & Company whitepaperChallenges facing early career women in thrombosis and hemostasis—meeting the needs of the next generation, Guest Editorial, J Thromb Haemost. 2022;20:2453-5455 Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.