Podcast Summary: Aspire with Emma Grede feat. Jessie Inchauspé ("Glucose Goddess")

Episode Title: Glucose Goddess Turned Sugar Hacks Into an 8-Figure Business
Air Date: February 24, 2026
Host: Emma Grede
Guest: Jessie Inchauspé (Glucose Goddess)

Episode Overview

This episode of Aspire with Emma Grede dives deep into the remarkable journey of Jessie Inchauspé, the widely-followed “Glucose Goddess.” Emma and Jessie discuss how Jessie transformed her personal health experiment into an eight-figure business, turning scientific glucose hacks into digestible content for millions. The conversation covers intuition-led entrepreneurship, the realities of bootstrapping, the challenges of building in the public eye, and the origins and science of her glucose hacks. They also explore how motherhood sharpened Jessie’s focus and her steadfast commitment to product quality and personal freedom.

Key Discussion Points & Insights

1. From Personal Health Crisis to Global Movement

• Jessie’s story begins at age 19 with a back-breaking accident, leading to years of mental health struggles and ultimately, a passion for biochemistry and self-experimentation with glucose monitoring.
• [06:03] Jessie describes her "origin story," linking blood sugar stability to improved mental health after using a glucose monitor (2018).
• The transformative moment: discovering blood sugar spikes correlated with mental health symptoms, and a drive to share findings with others.

“All of a sudden I was a channel for this thing. I was like, I need to tell the world.” — Jessie [08:02]

2. Science Made Accessible & Instagram Growth Strategy

• Jessie leveraged her strengths—a math and biochem background, product management experience—to simplify and visually present complex data.
• Her signature “famous graphs” made the science instantly understandable. She iterated content based on user feedback and optimized for shareability.
• [09:49] Jessie on her content strategy:

“I wanted to grow this content…to solve a problem. I need Emma on the toilet to see my piece of content.”

• Emphasis on building an audience through daily, shareable, useful content rather than product or monetary focus.
• Growth Timeline: Began Instagram in late 2019, reached 10,000 followers in six months through consistent, targeted effort.

3. Bootstrapping, Intuition, and Business Building

• Jessie turned down early VC investment because it didn’t “feel right,” instead relying on intuition to direct her next moves.
• [14:07] “Intuition. I was laser focused on how do I get this to the most possible people.” — Jessie
• Her first major break came when a literary agent found her on Instagram; the resulting book advance provided runway to build further.
• Jessie is proud of bootstrapping without investors, prioritizing autonomy and adaptability.

4. Turning Science into a Movement: The “Glucose Hacks”

• The “hacks”—practical, science-backed tips for blood sugar stability—became Jessie’s calling card and made her ideas viral.
• [35:02] “I had all this science…how do I make this into something that people are going to understand and are going to connect with? So it was the hacks.”
• Examples:
  • Savory breakfast over a sweet one for mental clarity ([36:05])
  • Veggie starter before dinner to blunt glucose spikes and aid sleep ([38:00])
  • “Put clothing on carbs”: Add fat/protein when eating sweets to reduce spikes ([41:36])
  • No all-or-nothing or shame—use hacks when you can as added tools ([44:16])

5. Founder Mindset: Quality, Setbacks, and Resilience

• Jessie’s ultra-high bar for product quality meant lower margins, but she refuses to compromise.

“I’m obsessed. I wanna make perfect stuff because I believe in them.” — Jessie [26:52]

• She describes the founder’s journey as “violent,” requiring constant resilience and obsession:

“Every day as a founder is a punch in the gut. So if you’re gonna keep going, you have to be obsessed.” [27:12]

• Overcame public speaking fears through repeated exposure (“it's like pushups, Emma”) ([32:03]).

6. Criticism, Trolls, and Industry Pushback

• Jessie has faced online criticism, industry trolling, and even legal threats for speaking out against misleading food marketing and “big pharma.”
• Emotional toll is real, but mission keeps her steady:

“You have to do it…It’s war, baby.” ([29:43], [35:02]) “I cry...then I have to find my center again and remember what I’m doing.” ([30:28])

7. The Science Behind Her Products & PCOS

• Developed “Anti Spike,” a supplement based on extensive research, not industry shortcuts ([58:29]). Flatly refused white-label offers in favor of building authentic, effective products.
• Connection between glucose, insulin, and conditions like PCOS:

“So many women who use my glucose hacks…their insulin comes down, their testosterone comes back to normal, and they ovulate again.” — Jessie [50:50]

8. Motherhood & New Focus

• Jessie shares how motherhood increased her efficiency, hunger, and decisiveness as an entrepreneur ([55:07]).
• “I thought motherhood might make me a bit softer … and it hasn’t. It’s made me more hungry. I don’t have much time and I want to do a lot of stuff.” ([55:07])

9. Freedom, Ownership, and Vision

• Jessie remains the sole owner, deeply values her business freedom, and hasn’t raised outside capital ([61:25]).
• Future investment possible only if it doesn’t impinge on freedom—her core value ([62:58]).
• Jessie prefers “advice networks” over formal mentorship.

10. Looking Forward: Mission & Legacy

• Jessie hopes her work eventually becomes “obsolete”—a world where glucose literacy is as ubiquitous as basic health knowledge ([71:32]).
• She credits unsung scientific researchers as the real heroes in her field ([69:06]).
• Next potential evolution: focus on mental health, with the same accessible, science-first approach ([72:51]).

Notable Quotes

• On simplifying science:

  “Magic starts here, but it’s all science.” — Jessie [05:15]

• On intuition over business plans:

  "No plan, intuition only. I just needed to hire one person." — Jessie [22:20]

• On product quality:

  “[My supplement] is the best product. I put Reducoes and [other molecules] in the same product…That’s way too expensive. Why would you do that?... Because it’s the best.” ([23:05])

• On resilience:

  “The only way to get better at push ups is to do the push ups. Same thing [with public speaking].” — Jessie [32:04]

• On hacks vs. shame:

  “You can’t fail at the glucose hacks. Even if just one time this week you think about putting clothing on those carbs, that’s better than doing it zero times.” — Jessie [44:16]

• On food and guilt:

  “I never feel guilty about food...If you’re eating it for pleasure, eat it for pleasure. If you’re eating for health, eat it for health. Just be aware.” — Jessie [74:57]

• On legacy:

  “For my work on glucose to become obsolete. I want to be useless. I want Glucose Goddess to be useless because everybody knows this stuff.” — Jessie [71:32]

Timestamps for Important Segments

| Timestamp | Segment/Topic | |------------|-------------------------------------------------| | 05:15 | Jessie describes “science with a little magic” and her blood sugar tips | | 06:03 | Jessie’s personal health crisis & journey to glucose hacking | | 09:49 | Building the famous graphs & product management approach to content | | 12:14 | Refusing VC money, intuition-led growth | | 14:07 | Committing to content, betting on herself | | 22:20 | Book deal & hiring first employee; “no plan, intuition only” | | 26:52 | Product obsession and founder relentlessness | | 27:53 | Emotional toll, criticism, resilience | | 35:02 | Turning scientific data into “hacks” | | 36:05 | Top glucose hacks: savory breakfast, veggies before dinner, protein | | 41:36 | “Clothing on carbs” hack explained | | 50:50 | PCOS, insulin, and glucose; reproductive health | | 55:07 | Motherhood’s impact on focus, drive | | 62:58 | Core value: business freedom over outside investment| | 69:06 | Unsung heroes: scientific researchers | | 71:32 | Jessie’s ultimate aspiration: making herself obsolete |

Memorable Moments

• Jessie’s candidness about almost running out of money after quitting her job—saved by a book deal ([14:25]).
• The “violent” nature of personal growth and persistence in business—a recurring motif throughout the episode.
• Her playful (and relatable) view on food and guilt, especially the ode to ice cream:

  “I ate the whole tub because I had to get a chocolate fix. That was my most recent pleasure purchase.” ([75:54])

• The playful banter around “protein trees” and discontinued ice cream flavors ([77:24]).

Final Takeaways

• Jessie Inchauspé’s success is built on distilling science into actionable, memorable tips—grounded in intuitive business-building and an unyielding focus on quality and mission.
• Her journey is a testament to building without a detailed roadmap: starting with intuition, maintaining integrity, and slowly compounding momentum.
• She empowers listeners to trust their intuition, not compromise their values, and to treat self-care as iterative, not all-or-nothing.
• The episode is rich with practical glucose hacks, founder wisdom, and a vision for democratized wellness, all delivered with Jessie’s trademark warmth, humor, and honesty.