In 1958, “The Blob” introduced the world to a menacing literal blob that could consume everything in its path. This month, we sit down with blob expert, Dr. Adam Hoppe, Associate Professor at South Dakota State University. He uses CRISPR to perform genetic screens and identify every genetic function inside our very own blob-like primary immune cell — the macrophage. His important fundamental work will someday help researchers create targeted immunotherapies to tap the body’s own defenses for fighting diseases.