Podcast Summary: "Call It What It Is" – Episode: CALL 080425 SHEMEDrev
Host: iHeartPodcasts
Guests: Dr. Ali Abadi, Jessica Capshaw, Camilla Luddington, Dr. Joy Hardin Bradford, Jeff Perlman, Rick Jervis
Release Date: August 4, 2025
Introduction
In this engaging episode of "Call It What It Is," co-hosts Jessica Capshaw and Camilla Luddington delve into vital women's health topics, featuring renowned OB/GYN Dr. Ali Abadi. The conversation aims to educate listeners on perimenopause, PCOS, endometriosis, breast cancer risks, and innovative treatments, all while fostering a supportive community for women navigating these challenges.
Guest Background and Connection
Jessica Capshaw and Camilla Luddington open the discussion by introducing Dr. Ali Abadi, a prominent OB/GYN based in Los Angeles. With over two decades of experience, Dr. Abadi is celebrated for her expertise in women’s health and her media presence on shows like Good Morning America and The Today Show. She also spearheads a fashion line, Haney, and co-hosts the SheMD podcast with her partner, Mary Alice, who hails from the fashion industry. Their diverse backgrounds bring a unique perspective to the conversation.
“She has been a stylist, an editor, and so much more. We’re thrilled to have her expertise today,” says Jessica Capshaw (02:43).
Raising Awareness on PCOS and Its Impact
The conversation shifts to Polycystic Ovarian Syndrome (PCOS), a condition affecting 15% of women and a leading cause of infertility. Rick Jervis shares his personal journey of discovering PCOS and its profound impact on his life, highlighting the lack of readily available information for women compared to men.
“75% of women with PCOS are unaware they have it,” Rick emphasizes (07:36).
Dr. Ali Abadi elaborates on the complexities of diagnosing PCOS in teenagers, noting that symptoms like irregular periods, acne, and weight gain often overlap with normal puberty changes. She stresses the importance of hormone testing and individualized treatment plans to manage symptoms effectively.
“You can’t just say, ‘You’re not 18 yet, so stay with your pediatrician.’ Most need specialized care,” Dr. Abadi explains (13:51).
Understanding Perimenopause: Definitions and Symptoms
A significant portion of the episode is dedicated to demystifying perimenopause—the transitional phase leading up to menopause, typically occurring 7 to 10 years before the final menstrual period. Dr. Joy Hardin Bradford provides a clear definition, stating that menopause is confirmed after 12 consecutive months without a period, with perimenopause beginning as early as the mid-30s.
“Perimenopause can start as early as 35 and presents over 100 possible symptoms,” Dr. Bradford outlines (28:17).
Key symptoms discussed include:
- Irregular periods
- Hot flashes and night sweats
- Brain fog and memory issues
- Weight gain and metabolic changes
- Vaginal dryness and painful intercourse
- Mood swings and anxiety
“It's a combination of these symptoms that warrant treatment, not just one isolated issue,” Dr. Bradford advises (31:09).
Breast Cancer Risk and Proactive Measures
The episode underscores the critical importance of understanding individual breast cancer risk. Dr. Abadi introduces the MyRisk genetic test, which evaluates a woman's lifetime risk based on factors like family history, genetic markers, and personal health data. She recounts her personal experience, highlighting how a genetic test revealed a 37% risk despite having no apparent risk factors, leading her to undergo a prophylactic double mastectomy.
“Knowledge is power. You need to know your lifetime risk to take appropriate preventative measures,” Dr. Abadi emphasizes (41:11).
She discusses the criteria for taking the MyRisk test, ensuring listeners understand that it’s essential for women with significant family histories or other risk factors.
“If your lifetime risk is 20% or more, you should start imaging as early as 30,” Dr. Abadi advises (35:06).
Innovative Treatments: GLP-1 Medications and Weight Management
GLP-1 (Glucagon-Like Peptide-1) medications emerge as a cornerstone in weight management and treatment for conditions like PCOS. Dr. Bradford and Rick Jervis discuss the profound impact these medications have had on their patients, noting significant weight loss and improved metabolic health.
“These medications are a game changer for patients with PCOS and obesity,” Dr. Bradford asserts (59:22).
The hosts explore the various GLP-1 options, including Wegovy, Mounjaro, and Ozempic, discussing their specific benefits and cardiovascular protections.
“Wegovy has cardiovascular protection, helping reduce the risk of coronary artery disease,” Dr. Bradford explains (57:23).
Hormone Replacement Therapy (HRT) and Breast Cancer Considerations
The discussion advances to Hormone Replacement Therapy (HRT), particularly for women at high risk for breast cancer. Dr. Bradford outlines alternative treatment options for managing perimenopausal symptoms without hormones, such as:
- Brisdal (Paxil): For hot flashes and night sweats
- Trazodone and Magnesium Supplements: To improve sleep
- Minoxidil: For hair loss
- Vaginal Estrogen Treatments: Including non-absorbed options for those with breast cancer
“For patients who can’t use hormones, we have effective non-hormonal treatments to manage their symptoms,” Dr. Bradford states (50:09).
She also highlights the importance of genetic testing for APOE4 mutations, which increase the risk of dementia, and how HRT can benefit these patients during menopause.
“20% of women carry APOE4, and for them, hormone replacement can reduce dementia risk,” Dr. Bradford notes (52:55).
Alcohol Consumption and Health During Perimenopause
Jessica Capshaw raises concerns about alcohol consumption during perimenopause, questioning its effects on health and hormone metabolism. Dr. Bradford shares her staunch stance against alcohol, referring to it as a “poison” and advocating for its complete elimination to improve overall health.
“Alcohol is a poison. I don’t drink, and I’ve limited my intake to maybe 20-30 drinks in my entire lifetime,” Dr. Bradford declares (65:42).
She discusses how GLP-1 medications can curb alcohol cravings, aiding women in maintaining sobriety.
“GLP-1s take the craving for alcohol away, making it easier to quit,” Dr. Bradford explains (64:55).
Empowering Women Through Education and Self-Advocacy
Throughout the episode, the trio emphasizes the importance of self-education and advocacy in women's health. Dr. Bradford encourages women to familiarize themselves with their symptoms and risks, enabling them to have informed discussions with their healthcare providers.
“Educate yourself about your symptoms and become your own health advocate,” Dr. Bradford urges (33:42).
Jessica Capshaw and Camilla Luddington echo this sentiment, highlighting the value of resources like podcasts to disseminate accurate health information and empower women to take control of their health journeys.
“We’re in this together, educating ourselves, and asking the right questions,” Jessica affirms (70:18).
Conclusion and Future Engagements
As the episode wraps up, Jessica Capshaw and Camilla Luddington express their gratitude to Dr. Ali Abadi and encourage listeners to seek out additional resources and support. They hint at future episodes that will delve deeper into various aspects of women's health, ensuring the conversation continues to evolve and support the community.
“We have so many more questions and topics to explore. Stay tuned for more episodes,” Jessica concludes (73:37).
Key Takeaways:
- Perimenopause is a complex transition with over 100 potential symptoms; individualized treatment is essential.
- PCOS affects 15% of women and is a leading cause of infertility; awareness and proper diagnosis are crucial.
- Understanding breast cancer risk through genetic testing like MyRisk empowers women to take preventative actions.
- GLP-1 medications are effective for weight management and can aid in reducing alcohol cravings.
- Hormone Replacement Therapy has tailored options for women, including those at high risk for breast cancer.
- Self-education and advocacy are vital for women to navigate their health effectively.
Notable Quotes:
- “75% of women with PCOS are unaware they have it.” — Rick Jervis (07:36)
- “Knowledge is power. You need to know your lifetime risk to take appropriate preventative measures.” — Dr. Ali Abadi (41:11)
- “Alcohol is a poison. I don’t drink, and I’ve limited my intake to maybe 20-30 drinks in my entire lifetime.” — Dr. Joy Hardin Bradford (65:42)
- “Educate yourself about your symptoms and become your own health advocate.” — Dr. Joy Hardin Bradford (33:42)
- “We’re in this together, educating ourselves, and asking the right questions.” — Jessica Capshaw (70:18)
This episode of "Call It What It Is" stands out as a comprehensive guide for women navigating significant health transitions, offering both medical insights and personal empowerment. By bridging the gap between complex medical information and accessible conversation, Jessica, Camilla, and their expert guests provide invaluable support for their listeners.