
Semi stocks soaring, as Intel and memory names jump double digits. How much more this trade can climb, and how our traders are positioning in the chip rip. Plus, Meta’s copyright complications, Coinbase cuts heads as AI shakes up the workforce, and the CEO of biopharma company Protagonist on its recent drug approval and the stock’s big run up over the past year. Fast Money Disclaimer
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Melissa Lee
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Melissa Lee
Live from the NASDAQ marketsite in the heart of New York City's Times Square, this is fast money. Here's what's on tap tonight. A new number one at least for a few minutes, reports after hours Google could be getting a massive order for its cloud chips, sending shares of Alphabet soaring. It briefly had a market cap. Eclipsing in videos will make sense of the moves and break down all the action in semis today. Embrace for turbulence. Flight cancellations are piling up as the Iran conflict continues. The implications as we head into the busy summer travel season and the ripple effects if people aren't traveling. Plus, Metta faces a lawsuit over how it trains its AI. Coinbase drops after announcing layoffs and counting down to Disney earnings. It's the first report under new CEO Josh. Tomorrow, what we hear about layoffs and breakdown of licensing deal with OpenAI and President Trump's battle with Jimmy Kimmel. I'm Melissa Lee, come to you live from Studio B at the nasdaq. On the desk tonight, Tim Seymour, Steve Grasso, Julie Beal and Marta Norton, chief investment strategist at Empower Investments. Welcome, Marta. And we start off with news that made Alphabet, at least very briefly, the biggest company in the world by market cap. The information reporting Anthropic has committed to spending $200 billion on Google's Cloud chips. Let's get to Mackenzie Sagalis for the latest and the details on this one.
Mackenzie Sigalos
Mac hey Mel, so Alphabet touching a $4.8 trillion market cap after hours, briefly putting it ahead of Nvidia following that report from the information on Anthropic Google cloud commitment now last month Google said it would supply anthropic with 5 gigawatts of server capacity start year. And now we have a dollar figure to go along with that commitment. It's 200 billion over five years. Google disclosed close to half a trillion dollars in cloud revenue backlog last week. So this would mean that Anthropic alone accounts for more than 40% of Google's future contracted cloud revenue. And remember Google investing up to $40 billion in anthropic, $10 billion now with another 30 billion that's tied to certain performance milestones and then in return it gets one of the biggest AI cloud customers in the market. It's another example of one of these chip for equity deals and it comes less than two weeks after Google unveiled its latest AI chips, the tpu, now specially designed for inference and training. It comes as they go head to head with Nvidia on their in house silicon. And worth noting here, Mel, across Amazon, Microsoft, Google and Oracle, contracts tied to anthropic and OpenAI now make up roughly half of the $2 trillion and reported cloud backlog.
Melissa Lee
Wow, strong players there Mac. Thanks Mackenzie seagallos Tim, there's so many ways to trade this. I mean I don't know if you want to go concentration in terms of the backlog to one customer or the fact that what it had been doing for its own business, we saw this with Amazon too in terms of its TPU business is now another revenue generating business on its own. I mean it's just fascinating how it's
Tim Seymour
playing out commitment to cloud and chips which is really important here. And yes, you know, one, one customer being 40% of the backlog but, but it's probably even going bigger is that between, you know, Anthropic and open air, you've got 50% of the backlog for all of them. And we've seen where this is in apples and oranges. But with Oracle, some of those commitments tied to the circular trade here are things that have been of concern. What you get to with Google is this is a company that not only continues to evolve, but their former place in search of situated on every handheld or every desktop continues to ring the register. We saw that in current revenues enhanced by AI, we're giving them clearly a pass on additional spend. In other words, when Metta and Google the same night announced an extra 10 billion each, Google went up 5%, Metta went down 10 to 15. So you know, the valuation is also not, not difficult. All these other businesses, we're not even going to talk about YouTube and Waymo, but these are exciting reasons to own
Melissa Lee
Google as Well, I mean the path to monetization for this one is clear. For Meta, as you mentioned, it is not. It's in terms of the spend. Yeah. Marta, what do you make of Alphabet?
Well, you know, I think it's a, it's a pretty exciting development and I think what's interesting is how much things shift. If we go back a year ago, I don't know if there was the same enthusiasm around Alphabet. And I think that underscores how much there is this rotating leadership among AI. We simply don't know who the winners are. And I think that justifies a very valuation conscious view where you want to move into these areas when they're cheap and move out of them as they get expensive because things are shifting in real time.
Is Meta cheap at this point then?
Well, it is cheap, but I think there are.
Relative to itself.
Exactly. But there's real questions as to, you know, a lot of these companies are able to, to put their whole infrastructure to work matters putting it to work in digital advertising. And so I think that's a different question for that particular company.
Steve Grasso
So when you look at a video, when you talk about concentration of revenues for, for or Google or Alphabet, when you look at Nvidia, they used to have the same problem. They had the concentration of revenues from the hyperscalers. And my problem was the hyperscalers, their biggest clients were making their own chips. Now we're seeing other people go to them instead of Nvidia. So this to me is when you're looking at it, Nvidia has had more lifelines than you could possibly imagine as a stock. They've been able to diversify away from the four hyperscalers. But this is another sign where you want to be selling Nvidia, which is
Melissa Lee
what has actually been, been happening.
Steve Grasso
I mean it took a long time to happen, but it's happening now.
Melissa Lee
Right? I mean, is this just sort of a rotation within the sector? Because we're going to talk about the larger chip rally today. But Julie Beal, I mean in today's rally it was notable. I mean, stocks up 4% and video is down a percent. The biggest component of that index can be down. I mean it's, it's really remarkable to think about how, you know, not dominant Nvidia is for being a dominant player.
Julie Beal
Yeah, it's, it is unprecedented. But I think it is this reflection that investors generally do not love customer concentration, particularly when it's your whole raison that their whole existence is about this handful of customers. And that's not true. For Google necessarily it is on the chip side, but I think for their broader business they have some level of insulation. I can really understand and recognize that it's true that we just don't know where the real benefits are going to accrue when we're talking about Gen AI. It feels like right now the easiest place to play it is in chips because they're making the money right this second versus the rest of it still feels pretty unclear. It's hard to recognize how OpenAI and Anthropic are really going to make money when memory is skyrocketing. And these types of chips are pretty expensive too. So I think this is the better place right now, at least the most transparent and visible place.
Tim Seymour
We've seen the semiconductor index go up 46% in 36 days and Nvidia hasn't really been part of it. Now this is a day where we're going to at some point, if not now, talk about Micron and Intel and what's going on for it.
Melissa Lee
Well, for Tim, I'm sorry to, I'm
Tim Seymour
sorry to be driving this train bus anyway. Well, it's just an extraordinary day and it just speaks to the where Google is. Google can trade very expensive to itself and it is, I think it's expensive to itself on recent history just because we know what it's done. But, but why can't it trade with a 30 multiple in a world where they seem to be the one that's also dictating the terms now, by the way, I mean how about tech costs for, for Apple and things that might have changed and actually gotten better for them? So you look at the move today though in Micron and you look at memory and the names that already reported and they're getting this second life because whether it's SanDisk or Seagate talking about solid state drives, it's really, it's, it's a, it's a moment where the valuations almost don't matter.
Melissa Lee
Yeah. Here's another move higher in the after hours. AMD shares are higher by 5% after the company beat on the top and the bottom line. The conference call kicking off just moments ago. CNBC's Christina Parts Neville has got the numbers and the latest. Christina?
Christina Parts Neville
Yeah, well the story out of AMD is demand and it's really coming from everywhere. Data center revenue jumped 57% year over year to 5.8 billion. That is the main driver of their business server cpu. Demand was a key driver as well. It lines up with what we heard from intel just last week and what we're likely to hear from ARM tomorrow. Agentic AI is driving a CPU renaissance. On the GPU side though, Lisa Su, the CEO, said customer forecasts for the next generation Mi450 chips. These are the next generation GPUs and their Helios rack systems are exceeding initial expectations. One flag worth watching though is datacenter revenue was only modestly higher quarter over quarter, which raises the question of whether TSMC capacity is already acting as a ceiling. Keep in mind amd is like 100% dependent on TSMC. And SU even told investors in the press release, quote, unquote, we expect server growth to accelerate meaningfully as we scale supply to meet demand. But she hasn't addressed it just yet on the call, it's only just begun on margins. Q1 came in essentially in line with expectations at 55% and the Q2 guide steps it up to 56%. With the stock price for perfection. Investors will want to see that number move a little bit higher as the mix scales. And Melissa, just now they posted the full transcription of Lisa Su's remarks. So I'm saying this before she's even said it. They did outline a server CPU market growth at approximately 18% annually over the next three to five years. They said that back in November of last year. They're saying, according to Lisa Su right now, based on the demand signal specifically by Agentic, they now expect their server CPU total addressable market to grow greater than 35% annually, reaching over $120 billion by 2030. So that is probably why you're seeing the stock now move higher, up to 6% percent, guys.
Melissa Lee
So now they're seeing it grow double, basically what they forecasted not that long ago.
Christina Parts Neville
Yeah, it was 18% back in November over the next three to five years, not one year. And now they're saying that that's essentially going to double 35%.
Melissa Lee
Yeah, that's an extraordinary jump still. Christina, thanks. Keep us posted on that. And this sort of gets to this notion that the picture is really evolving every single day and that the confidence with which you CEOs are coming out saying the pipeline is this demand this much into the future. And that's why we're seeing the rerating in the memory stocks in intel and amd. Can you buy that though?
Well, I mean, they buy it, right? The CEOs are sure a lot of conviction behind it and a lot of their own money behind it there. I mean, some of these companies are gambling their futures on the AI trade being alive and well, and a new infrastructure for the U.S. i see. Still think that there's validity to that thesis. I want to be part of the trade. I'm less concerned about Nvidia. I still think there's, there's, you know, a valuation opportunity there. There is a lot of kind of questioning around that type of company. So yeah, I think there's room to be bullish on this.
Tim Seymour
Well, I think there's no question that the street is bullish and there's no question that we're seeing analysts take a 30 multiple to a 35. 36 is how you get from 300 plus. You upgrade, you get a beat in a raise. You have helios coming online, second half and actually meaningful revenues in 27. This is what we were waiting for. My 400. What's happening with that? Well, we're now hearing that it's demand is better. Gross margin comes in at 55. You can suddenly throw your EPS at 13 bucks a share at 35 times, you can get to 475. And that's what's happening here. And again, we're not seeing a. It's never been a question about demand on the chip side. We know it's not a question of demand on, on the memory side. But I'm long amd. I know it hasn't really made sense, but to this point, this is the rotation that sometimes you're even just lucky to be there.
Steve Grasso
This has been a winner. If you look at year to date performance, it blows everyone else away with you look at Texan Texas Instruments actually is pretty surprising too with their year to date. So it's the ones that you wouldn't think about are having actually a year to date performance. And remember last earnings it guided, it had a poor guide and the Stock traded off 17% and it also had a sequential revenue decline and it had a margin step down. Now you reverse that, put it on its head and you have everything that works out. For amd. It was a laggard, now it's a leader. Nvidia can't afford to lose the chips war and everyone else, it just helps them. It's a tailwind.
Melissa Lee
It might not. I mean there's a couple of ways of looking at this. I mean you can say that Nvidia is losing to the rest because investors, Julia, at this point are looking for the rocks that haven't been turned over. And obviously they're clearly turned over at this point with these runs. But maybe that was sort of, you know, why we saw the dispersion away from Nvidia and into even a Texan which is really known for industrial applications and all of a sudden has this data center business which is meaningful to the way investors see that narrative.
Julie Beal
You see it everywhere. I think it's not even just within the chip sector. I think you're seeing it in electrical companies that have tangential connection to data centers.
Tim Seymour
Right.
Julie Beal
Everyone is trying to push this trade I think beyond necessarily where it makes sense. A lot of those are cyclical companies that don't necessarily have a lot of competitive protections. But I think what's so interesting right in this renaissance, particularly on the memory side, is think about SanDisk. Western Digital owned SanDisk spun it out. They're in that business, they know what the drivers are, they spun it out and now they're not benefiting from that value. If they themselves didn't know the value, how are most investors going to figure that out? I really think it's this question of people going where the revenue is right now rather than trying to necessarily gauge where it's going to be in the future.
Melissa Lee
For more on all today's after hours tech move, let's bring in Giloria, head of technology research at DA Davidson. He joined us on the fast forward. Gil, great to have you with us. I'm not sure where you want to start. I wanted to start first with the Anthropic and Alphabet. You cover Alphabet, you also cover the chip space. How meaningful is this for Alphabet?
Gil Laurier
Well, if the report is correct and the 200 billion are already were already included in the backlog that Google reported, it's actually not great news. If you remember the backlash on Oracle was when we found out that most of their backlog was from one customer OpenAI. There was even backlash on Microsoft when we found out a lot of their backlog was OpenAI as well. So. So it's actually not great news that that doubling in backlog that would look so impressive is actually just one long term deal with anthropic. Having said that, Anthropic is hot right now, so they'll probably get more credit for it. But realistically what it means is that their backlog without anthropic is very concentrated in anthropic without anthropic their backlog is actually less than half of Microsoft. So Microsoft with 630 billion of backlog has a lot more than Amazon. It's 460 and Google at 460 that are just as concentrated as it is. So you know, as we look at this AI trade, what we're seeing is three companies that look very similar in their prospects and their growth rates. Microsoft, Amazon and Google are trading in very different valuations. Amazon and Google are very in favor right now. They're trading at 27 forward earnings. Microsoft at only 21 times earnings on what are really similar prospects. And again, Microsoft even has a lot more backlog, a lot more visibility into its growth than Amazon and Google do.
Tim Seymour
Hey Gil, it's Tim. So I was going to ask a different question, but now you've just said that it sounds like you're bullish Microsoft over Google and that's not a, that's not a consensus call. I'm also curious to hear you think that there are three essentially equal companies when in fact part of the, part of the story here for Google is that I mean this news to me is less about anthropic than it is about TPU's and you know, the chip, the chip business for them overall. So but you know, talk about even drilling into those stocks you just mentioned.
Gil Laurier
Yeah, so I think all three are going to do very well. Let's be clear. All of a compute is going to one way or another comes through these three companies. They have all the customers, they have all the enterprise customers, they have all the consumer customers. These three are going to do phenomenally well. I'm just pointing out the, the valuation discrepancy now on the tpu and Amazon made a big deal out of its training. Jensen Huang has pointed out that really that's almost entirely anthropic. Right. So because Amazon and Google are investors in anthropic, they, they require anthropic to use their chips. It's not that there's a lot of other customers for these chips. Now mind you, the chips are good. GPUs are actually the second best alternative to Nvidia's GPU. But these GPUs are still a lot better and a lot more productive. A lot more, a lot lower cost of ownership at the if you're thinking about the output level. So not sure ready to give Google that much credit. Although they're a close second. I think Amazon's a little bit of a pretender with training. I think there was a little sleight of hand on the last conference call, but Google does deserve credit on tp but, but only so much credit. Again, comparing, comparing how in favor Google is and again out of favor Microsoft is.
Melissa Lee
Gail, great to speak with you. Thank you. Gil Laurier.
Gil Laurier
Thank you.
Melissa Lee
He basically said Andy Jassy was sort of, I don't say lying maybe exaggerating the truth. I mean they said at a $50 billion revenue run rate it would be the third biggest data chip data center chip company in the world. And Gill is totally throwing shade on Jassy.
Tim Seymour
Shade.
Melissa Lee
No one to say like lying. That's like too that's too harsh. But the Would you rather that Gil imposed upon himself choosing Microsoft over Google was interesting to do you would you agree it is out of consensus Microsoft has been caught up in the software SaaS Apocalypse Concern.
Sheila Kialu
Yes.
Melissa Lee
Is it interesting caught up with that? I do think it's interesting and frankly, you know, I think software generally is interesting. Generally is the wrong word because I do think you have to pick your spots in that space. There's obviously transformation, but I do think Microsoft is one of those companies that strikes me as a company that's nimble enough has the financial wherewithal to think through how to survive a software AI world.
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Melissa Lee
Welcome back to Fast Money CBO. Seeing as an odd volatility pattern in the market, let's bring in Mandy Hsu, the firm's head of Derivatives Market Intelligence. Manny, great to have you with us.
Mandy Hsu
Great to be here Melissa.
Melissa Lee
What is so odd?
Mandy Hsu
Well, when you talk about volatility generally people Associate volatility with market selling off. We generally see higher volatility on market down days than up days. But when we look at how the market has behaved over the past two months since the Iran war started, what's been really unusual is that the volatility has come from the upside. So in March when the market was selling off, it was very modest, very contained. There was very, there was very little panic in terms of investor, you know, rushing for protection. And then it's really the sharp rally higher that has caught people off guard. And that's what we've seen people scrambling for options, not put options but call option to really adjust their portfolio exposure because they were not really prepared for this sharp rally higher.
Melissa Lee
Okay, so is that what you're seeing repeatedly or is that just what you've seen cumulatively over the past month or so?
Mandy Hsu
So I would say repeatedly over the past couple of weeks, especially in April, there were a couple of days where in the S and P more calls traded than puts, which for the S and P index is very unusual because typically people buy index options more to hedge. Right. So, and that hasn't happened in many years. So. So we're definitely seeing it in skew patterns in terms of the cost of puts versus calls, puts getting cheaper, calls getting more expensive. We're seeing it in the volumes and we're seeing the way that the S and P behaves.
Tim Seymour
Do we see these patterns though, Mandy, at inflections points before something else is about to happen, I guess is my question. And it does seem as if, boy, isn't it a great time to be selling volume if I'm wrong. But I'm more worried about the next move.
Mandy Hsu
Yeah, no, so that's a, that's a great question. So in terms of option market positioning, when it gets to extremes, it certainly can kind of flag when position gets to, to one sided. But when it comes to the kind of the way the market's behaving, where we're seeing more just S and P, bigger moves on the upside to downside, that's only happened once before in the past 20 years and that's in 2022, if you recall. That was also a large sell off in the market, down 20%. But it was gradual throughout the course of the year. And it was a very similar environment where there was very little demand for downside protection because people were well hedged going into the sell off. And actually it was the sharp moves to the upside that were more painful for investors.
Steve Grasso
Is there a chance to. Tim's question if this was so dominated by tech and software and those names that make up that bracket where they were sold off and they were bought back so aggressively, is there a shot that the next leg, instead of an inflection point, the next step up can be the other 493 stocks or the other groups or Russell names or anything else?
Mandy Hsu
Yes, certainly. One thing we've noted is just how concentrated this rally has been in the tech names or the chips names. You know, tech is up, I think almost 20% over the past month. But if you look at the other sectors, I think five of the sectors in the S and P are barely changed, like flat over the past month while the market has rallied. Another way you can look at it is the equal weight. S and P index is still below the February highs, while S and P, the market weight is obviously making new all time highs. So certainly I think in terms of the next leg, higher would be a healthier rally to me. If we start to see that broadening out. We saw that trade in February, people rotating to the other sectors. You haven't seen that yet, but if you're a bull or if you're looking for that reason to get bullish, I think that could be the next leg, certainly.
Melissa Lee
Mandy, thanks. Good to see. Manny Xu of cbo, do you want to see that broadening out? I mean, what we haven't seen in particular this, I mean, financials, financials have sort of been left out there.
Well, it's fascinating because what people say makes a healthy market is a broader market and we have seen small caps participate. But I would argue that's partly an AI trade, right? It's in its energy, it's industrials. A lot of those are related to this broader AI build. I guess the big question I have for people, people when we think about the broadening out, a lot of that was predicated on fiscal stimulus, monetary stimulus, Fiscal stimulus in play, but offsetting higher gas prices, monetary policy, stimulus, is that still in play? And so I guess I just, I still think that we could see broadening out on the margin, but in the main it is still an AI world.
Julie, your thoughts?
Julie Beal
I completely agree with everything that she says. It's really important that we see broadening because it just creates a much more stable market. When we don't have that, then we have the reversions where people suddenly get anxious about AI. And I think when you have any technology transition, you have those moments where, you know, suddenly people really don't believe in it and then people believe in it. Again and it just creates a lot more volatility than needs to be there. She's absolutely right. Small caps right now, it's not been a quality rally. There's a huge gap in ROEs because companies with higher ROEs and small cap have been totally forgotten versus these very, very cyclical lower ROE companies are the ones that are really coming to the fore. I don't think that's a very sustainable trend for me. It's nice because mostly these are premium companies that are typically expensive for me to buy and they're cheap right now. But it is an unusual and not very sustainable pattern.
Melissa Lee
There's a lot more fast money to come. Here's what's coming up next.
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Melissa Lee
Welcome back to Fast Money Shares of meta platforms under pressure Today, the social media giant facing a lawsuit over how it is using copyrighted material to train AI. CNBC's Julie Borson's got the details there, Julia.
Julia Boorstin
Melissa, that's right. Meta is being sued by a group of publishers over copyright infringement. They allege that the tech giant used their books and articles to train its AI model, Lama. Now the plaintiffs include big publishers such as Hachette, McMillan and McGraw Hill, along with author Scott Turo. The class action lawsuit claiming that Metta and CEO Mark Zuckerberg, quote, reproduced and distributed millions of copyrighted works without permission without providing any compensation to authors or publishers. Going on to say Zuckerberg himself personally authorized and actively encouraged the infringement. Meta responding to the lawsuit, saying in a statement, quote, AI is powering transformative innovations, productivity and creativity for individuals and companies. And courts have rightly found that training AI on copyrighted material can qualify as fair use. We will fight this lawsuit aggressively. Now, this is not the first time Meta has been sued by authors for copyright infringement as it relates to AI training. Just last year a federal judge ruled in favor of Meta in a similar case. But there is also precedent that rules in favor of copyright holders. Last fall, Anthropic agreed to pay a one and a half billion dollar settlement to authors and publishers whose books were used to train its AI. So Melissa's going to be fascinating to see how this one shakes out.
Melissa Lee
It will, Julia. Thank you. Julia Borson, as you saw there, the stock today in response to the news didn't really move much. It hasn't really moved much though since the earnings drop, it has remained basically where it is right now. It hasn't caught, it caught a bid higher or anything like that. So, so we were talking about that earlier. Is that fair?
Well, it's funny because you contrast it with the prior earnings season and Meadow was one of the companies that people are rewarded because they could see a through line to monetization. I like these unfair moments because they create opportunity from a valuation standpoint. I think there are legitimate questions and though in of terms, terms of how Matter ultimately puts all of its spending
Tim Seymour
to work, well, I mean, look, their first quarter numbers were excellent. Okay? They, they beat expectations and it was, they, they've kind of dominated and helped a handful of companies really dictate this almost clownish EPS number that we have for the overall market. I mean it's extraordinary matters right there. History I met, it is they kind of apologize later. They kind of like to break stuff. This is not uncommon. I think the market recognizes that and they've largely rarely really been hurt in terms of market cap historically. I mean you have those recent child safety rulings against them as well, which are not over and probably will pick up some steam. But this wouldn't be a reason for me to sell Metta.
Steve Grasso
See, I don't like the fact that they knew. There's going to be plenty of stuff
Melissa Lee
that you don't know they allegedly knew.
Steve Grasso
So they, they allegedly knew. But, but it looks like they knew even though they allegedly knew. It looks like they just lean that way. So let's just, let's just say there's, there's stuff that you can know and steal and don't worry about it and there's a bunch of stuff that you're not going to know.
Tim Seymour
You're still what kind of stuff do you know and steal and think I'm talking about AI.
Steve Grasso
Yeah I'll talk about an AI. So when you're a copy when using copyright stuff, there's going to be enough of these minefields, I think that you have to stay away from things that are copyrighted already. But this is not just a meta issue. This is an everything in the issue.
Melissa Lee
Coming up, a cruel summer for airlines, how carriers are dealing with soaring jet fuel costs and just how bad it could get this travel season. Fast Money's back into. Welcome back to Fast Money. Stocks getting a boost as oil pulls back. The Dow climbing more than 350 points. The s and P and Nasdaq both closing at fresh record highs. WTI crude down about 4% settling above $102 a barrel. Shares of PayPal dropping nearly 8% despite topping EPS and revenue estimates. The Fintech reportedly plans to cut 20% of its staff over the next few years as PayPal looks to reduce costs and turn things around. Shares down 85% from its all time high set back in 2021. Coinbase shares in the red today after saying it would lay off about 14% of its staff or about 700 employees. CEO Brian Armstrong attributing the decision decision to AI disruption as well as market volatility. The company reports earnings on Thursday and some more after hours action. Arista Networks dropping despite topping EPS and revenue estimates. Gross margin coming in a little light. Klaviyo dropping after giving weak outlook. Also announcing its CFO is stepping down. And Super Micro higher after beating earnings expectations, posting better than expected guidance. Meantime, jet fuel prices have nearly doubled since the start of the Iran war and higher costs are causing airlines to to cut thousands of flights. This morning on Squawk we sat down with Kepler's director of commodity research, Matt Smith, who said it could get worse before it gets better.
Dinesh Patel
Asia is not getting the crude that it needs to refine into the jet fuel. And so they're trying to meet their domestic needs and they're struggling to meet the export needs as well. And so it is a series of dominoes that are falling here. And so jet is the first one to go. Asia is the first region, but it's going to spread across the globe and it's also going to spread across the products as well.
Melissa Lee
For more on the state of airlines and what it could mean for your future travel plans, let's bring in managing director Jeffries, Sheila Kialu. Sheila, great to have you with us. Matt also went on to say that there will be more flight cancellations beyond the ones that were already announced. We'll see them. We're seeing them in Asia, we're seeing them in Europe, but there will be more that. It is a call car wreck happening in slow motion. Those were his words. Would you agree? And how much of this is priced into the stocks, if at all?
Sheila Kialu
Sure. Thanks, Melissa, for having us. I would say we are going to see more cuts. A lot of the airlines have sold out their schedules three months in advance. So what we're seeing for the month of May is capacity is flat versus last year. But we are seeing capacity cuts into the second half of the year. For instance, United was going to grow the number of flights they had 5% year over year. Now they're talking about 1%. Same with Delta. So we're seeing capacity only increase about 1% versus the historical 3 to 5% capacity growth. And that's what's happening in the space. So we're going to see capacity come in, which means prices are going to go up because there's limited seat availability.
Steve Grasso
So, Sheila, when I look at this, I quantify and tell me if this is the way you. Or quantify or this makes sense. So UAL has the most Asian legs. So if I'm looking at it that way, they're going to be under the most pressure. Delta has its own refinery. No one else hedges. I should say the US Carriers don't hedge. European carriers still hedge. This is a Asia problem. This is a European problem. It's not a huge problem right now for domestic airlines. And when you look at the performance, Delta is outperformed. Am I looking at it the right way on legs or refineries or jet fuel?
Sheila Kialu
I'm actually surprised at the strength of the airline performance versus the commercial aerospace manufacturers I cover. The reason the airlines are outperforming the OEMs right now, it's because there's limited capacity. So they're passing through price increases in the realms of 20 to 30%. At some point there'll be demand destruction because everything is going to be more expensive and they'll have an inability to do that. But right now the winners like Delta and United are winning in terms of global capacity. Taking a quick step back, we're seeing further capacity cuts in Europe. We have a real time engine utilization proprietary Data set that's down 5% year over year in the month of April in Europe, Asia is down 1%. US is actually growing capacity up 1 1/2%. So nothing to write home about. But the winners are going to be who could pass price through and who's going to be in the best competitive position. From a fuel perspective, none of the US carriers are going to face a big fuel shortage. It's going to be more of a concern in Europe and the lower cost carriers in Asia that have some credit
Melissa Lee
risk in terms of that point of demand destruction though, Sheila. I mean, it seems like that point will be reached faster just given the structural issues surrounding jet fuel and the need to cut capacity, which will then drive that, that level higher. Plus the weight on the consumer of the inflationary pressures that are being felt, particularly in the regions that have the shortage of jet fuel, like Asia and Europe.
Sheila Kialu
Yeah, but not in the U.S. the U.S. carriers, we heard them report in the last two weeks, they're adamant, they're seeing the price increases pass through and part of that is airfares have been a deflationary product. You haven't seen them grow as a percentage of gdp. They haven't really grown in real terms. So this is their heyday and they're taking advantage of it. Especially the ones that could operate at a premium and the ones weren't are being eliminated as obviously we've seen Spirit Airlines shut down.
Melissa Lee
Sheila, thanks. Great to see you. Sheila Kyoulou.
Sheila Kialu
Thank you.
Melissa Lee
Jefferies. Julie Beale. Are you booking your flight to Asia anytime soon?
Julie Beal
Not, not to Asia, but it is a really interesting dynamic for airlines because it's really true that when you get these oil shocks, they tend to really pull back on their capacity and, and that leads to immediate improvement in their profitability because suddenly pricing is so much firmer and they actually become more efficient. So in a strange way, oil prices can be really positive and beneficial for their investor base. For us as consumers, it's not great news but it really will depend on do you have the kinds of business customers who aren't going to notice that your ticket price has increased. What's helpful for them is we all see the price at the pump as we go work and go do everything else and so we can recognize. Yeah, it makes sense that my ticket is more expensive. Oil prices have gone up.
Melissa Lee
Yeah. By the way, Spirit Airlines going out also has an impact on the industry which we haven't sort of factored in.
Tim Seymour
Yeah, some capacity cuts. I mean I saw system capacity is down about 310 basis points since the Iran war started. So as everyone has kind of said here, falling capacity, rising, rising revenue per available seat miles, also known as rasm. So it's good for airlines in the short run. I totally believe there will be demand destruction. In fact, my wife doesn't know this yet, but I think we're probably not going to fly down to the in laws for Thanksgiving. Just kidding.
Melissa Lee
It's a rough way of finding out. Don't want to be you when you get home. Coming up, driving the narrative, our protagonist Therapeutics is shaking up the biopharma space with their recent drug approval. And the stock can keep climbing after more than doubling over the past year. The CEO will join us for when Fast Money returns. Welcome back to Fast Money. With Big pharma racing to replenish pipelines, protagonist Therapeutics is among the biotechs that have stayed independent while prioritizing licensing deals with the likes of Johnson and Johnson and Takeda. Shares have more than doubled over the past year. The company just reported first quarter numbers a loss of 5 cents a share in revenues of more than 56 million. Those results not comparable though to estimate shares up about 2% after hours for more. Protagonist CEO Dinesh Patel joins us now. Dinesh, great to have you with us.
Dinesh Patel
It's such a pleasure and honor to be invited on the show. Really appreciate it.
Melissa Lee
We'd love to hear about icotide, which is your FDA approved treatment for psoriatic arthritis. Excuse me, severe plaque psoriasis. I'll get that straight. Johnson, Johnson and Johnson is projecting that it's going to be a $10 billion drug at peak sales. Help investors understand because this is a very interesting model. This is licensing and so you're going to get payments which will enable you basically to fund your future pipeline. Can you walk us through what the assumptions are and how much money you'll have?
Dinesh Patel
Yeah, absolutely. So icotide is a very unique drug. It's a first and only of its kind in the space and just to explain Briefly, it's an iO23 blocker and typically that mechanism has been dominated by blockbuster category drugs like Skyrizi and Trumpya. I mean, there are a lot of TV commercials around those kind of drugs, but those are all injectables. Whereas what we have done is created an innovative peptide which could be taken as an oral pill once daily. So our drug combines both the efficacy as well as amazing safety of the injectables, but with the convenience of a once daily oral pill. And that's why, and if you look at the market projections of drugs like Skyrizi and Trumpy, they are north of 20 billion and 10 billion respectively. So of course with icotide, it's no surprise that, you know, estimates over 10 billion are a normal belief. And we would say, you know, this is just the first innings. It has been approved for psoriasis. But if you look at the history of our 23 blockers, they also typically seek approval in psoriatic arthritis, ulcerative colitis and Crohn's disease. So those phase three studies are also ongoing. So when you combine all this, it creates a wonderful partnership where Pharma does what it is very good at doing, which is developing drugs and commercializing them, and a biotech like Protagonist does what it is very good at doing, which is innovating new medicine. And early on we were able to structure a very nice deal with them, dating all the way back to 2017. Gives you an idea of how long it takes. Right. And it's a win win situation. So with the revenue forecast that we have, with the 6 to 10% royalty in mind and 500 million plus in additional milestones, it's going to be providing us with a very steady stream of revenues for more than a decade at least.
Melissa Lee
Yeah, and that's not, we're not even talking about rest for tide at this point, which is the. You have in partnership with Takeda. What is the timeline on that in terms of FDA approval? Because that could potentially be another cash source for further funding of the pipeline. And also shareholders will be interested. You've already said that you're going to return capital shareholders. So all of that funding, all of
Dinesh Patel
that unicorn in our space, because this is very unusual for biotech to getting one drug approved. And Resveratide, which is a rare blood disease drug, partnered with Takeda, FDA has granted us priority review and hopefully if all goes well, that drug will also be approved in the third quarter of this year. So Protagonist could be having two drug approvals under its belt this year. And when you look at the normal statistics, right, There are about 40 to 50 drugs approved by the FDA in a typical year around the entire pharmaceutical sector. So clearly this is going to be a landmark year for us in that regard. And I refer to both resphatide and icotide as, you know, something where we did, which is very necessary in our industry, meaning partnership with pharma. I refer to it as symbiotic relationship. One needs the other. Right. And vice versa. So yeah, respiratory itself, you know, we recently opted out of the commercialization. Right. So now we are will be focused on garnering 14 to 29% royalty from Resphatite cells if when it gets approved. So very steady stream of revenues from two products basically.
Melissa Lee
Yep. That's unusual to hear from a biotech. Dinesh, great to have you with us. Hope you come back and keep us updated.
Dinesh Patel
Yeah, it was my pleasure. Thank you.
Melissa Lee
Coming up, Disney earnings on deck. But can the media giant bring a touch of magic to the report as shares continue to struggle this year? What do you expect? Welcome back to Fast Money. Disney on deck to report earnings before the bell tomorrow. Its first earnings report under Josh Tomorrow, who took over from Bob Iger, a CEO in March. Disney faces a slew of challenges early in tomorrow's tenure, from layoffs to a breakdown in its licensing deal with OpenAI saw a video generating feature to a battle with the FCC stemming from Jimmy Kimmel's criticism of President Trump. Tim, what do you want to hear from Disney?
Tim Seymour
Well, I guess I still want to hear where the profitability is on dtc, but I think the focus will be on the summer box office. And certainly, you know, we had that conversation with Wendy Feynman yesterday. I mean Disney in terms of sequel equals and some of the, the their ability to kind of roll the machine out and that was the term she used and she was really impressed by it. You know, I think is going to continue to pay dividends in terms of that flywheel. The problem is it's been very difficult to move the stock and even a company that under Bob Iger a year or so ago gave us incredibly detailed three and a half year projections on growth. I think the market still needs to see it.
Melissa Lee
Yeah. Julie, your take on Disney.
Julie Beal
Yeah, I think it's really dependent on the content that is the moat around this business. Right. We just had this copyright lawsuit and I think it's still unclear how they are really leveraging that scale and that content in order to drive better results, especially in streaming. So that's the place that I'll probably be paying the most attention to.
Melissa Lee
Yeah, I mean, parks have been strong for Disney. It'll be interesting to see how that has changed, if at all, given the circumstances during the quarter.
Yeah, I think there are some consumer tells that we can pull from Disney, especially given concerns around airlines, concerns around just the consumer pinch that they're feeling. So we'll get a read on that discretionary.
Steve Grasso
Yeah, there's got to be a clean beat or a clean momentum with streaming, and parks have to still show some sort of a tailwind to it. But we did that airline spot. If people are cutting back or flights are getting canceled and they're too expensive, you might see that be a little squishy.
Melissa Lee
Right. New CO2 kitchen sink is a possibility. So yeah, that should be interesting. Up next, final trades, final trade time.
Julie Beal
Julie Beal Hinge just reported some really solid results.
Melissa Lee
It's worth looking at.
Marta Norton, Mag5AI is cheap.
Tim Seymour
Tim Nice to have you. Marta Great to have you here. And I'll say J and J, the licensor of that protagonist, Steven I think
Steve Grasso
if you go down the rabbit hole on airlines and jet fuel, you'll find that the one that is the best position is Delta.
Melissa Lee
Right?
Marta, it was great to have you. Hope you'll come back. Martin Norton, thanks for watching Fast Money. See you tomorrow back here at five. Mad Money with Jim Cramer starts right now.
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Melissa Lee
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Episode: Intel & Memory Stocks Surge… And Protagonist CEO On Drug Approval
Air Date: May 5, 2026
Host: Melissa Lee
Panelists: Tim Seymour, Steve Grasso, Julie Beal, Marta Norton (Empower Investments)
Special Guests: Mackenzie Sigalos, Christina Parts Nevelis, Gil Laurier, Mandy Hsu, Sheila Kialu (Jefferies), Dinesh Patel (Protagonist Therapeutics)
This episode of "Fast Money" dives into a whirlwind day for tech and biotech investors — particularly the after-hours surges in chip, memory, and cloud stocks after blockbuster announcements from Google and AMD, and breakthrough developments in biotech with Protagonist Therapeutics’ new drug approval. The panel also dissects the mounting airline industry turbulence due to jet fuel shortages and Meta’s new copyright lawsuit over its AI training data. Notable industry guests weigh in with actionable insights for investors.
[00:56-08:30]
“When Meta and Google the same night announced an extra $10 billion each [in investment], Google went up 5%, Meta went down 10–15. So you know, the valuation is also not difficult.”
— Tim Seymour [04:09]
[07:33-13:42]
“It was a laggard, now it’s a leader. Nvidia can’t afford to lose the chips war and everyone else... it just helps them.”
— Steve Grasso [12:32]
[14:27-18:08]
“All compute is going to one way or another come through these three [Amazon, Microsoft, Google]. They have all the enterprise and all the consumer customers... but Microsoft has a lot more visibility into growth.”
— Gil Laurier [16:48]
[20:34-25:40]
“If you’re a bull... I think [broadening out] could be the next leg, certainly.”
— Mandy Hsu [23:13]
[27:48-31:23]
[32:53-38:15]
“This is their heyday and they’re taking advantage... pricing is so much firmer and they actually become more efficient.”
— Julie Beal [37:01]
[39:02–43:33]
“With revenue forecast and 6–10% royalty... it’s going to be providing us with a very steady stream of revenues for more than a decade at least.”
— Dinesh Patel [41:44]
[43:36-45:34]
| Segment | Topic | Speaker(s) | Timestamp | |--------|-------|------------|-----------| | 1 | Google/Anthropic News & Chip Sector Rotation | Melissa, Tim, Mackenzie, Steve, Julie, Marta | 00:56-08:30 | | 2 | AMD, Memory & Semis Rally | Christina, Tim, Steve, Julie | 08:30-13:42 | | 3 | Analyst Deep Dive: Cloud & AI Valuations | Gil Laurier | 14:27-18:08 | | 4 | Market Volatility, Rotation | Mandy Hsu, Melissa, Julie | 20:34-25:40 | | 5 | Meta Copyright Lawsuit | Julia Boorstin, Melissa, Steve, Tim | 27:48-31:23 | | 6 | Airline Capacity Cuts & Fuel Squeeze | Sheila Kialu, Steve, Julie, Tim | 32:53-38:15 | | 7 | Protagonist CEO On Biotech Deals | Dinesh Patel, Melissa | 39:02–43:33 | | 8 | Disney Earnings Preview | Melissa, Tim, Julie, Steve | 43:36-45:34 |
Lively, insightful, and fast-paced, with a focus on actionable investing ideas. The panel balances skepticism (on valuations, sector concentration, and near-term hype) with clear appreciation for long-term technology and healthcare innovation.
This "Fast Money" episode offers a broad sweep of actionable updates for investors, from the ongoing AI and semiconductor boom and its portfolio implications, to new risks in travel/airlines, to headline-grabbing legal and biotech developments. Not only are megacaps like Alphabet, Microsoft, and Nvidia at the center, but the episode delves into tactical trades in memory/chips, biotech outperformance, and even the knock-on effects in adjacent sectors like airlines and streaming media. The show’s signature roundtable ensures debate on where the puck is going, making it essential listening for investors watching the next wave of sector leadership.