Transcript
LinkedIn Advertiser (0:00)
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Dr. Samantha Yamin (0:33)
AI is popping up everywhere these days. From writing essays to detecting diseases. It's changing the way we work, think, and even care for one another.
Dr. Jodi Halpern (0:43)
A lot of people are just using GPT4 and saying, if you were a therapist, what would you tell me? And we know that that's not protected in the ways you might want. Mental health information.
Dr. Samantha Yamin (0:53)
When it comes to mental health, that raises some big ethical questions. Who's responsible when AI gets it wrong? How do we balance innovation with privacy? I'm Dr. Samantha Yamin and this is Curiosity Weekly from Discovery. Today I talk about the intersection of artificial intelligence and mental health care with Dr. Jodi Halpern. She's a professor at UC Berkeley's School of Public Health. And then later, we deep dive into fracking because I really wanted to understand what it's all about. But first, let's talk about luxury tourism. You've seen the White Lotus, right? The new HBO season just dropped on February 16th and you know I'll be dancing on my couch to the theme song the second episode one drops. But since this is a science show, let's talk science. Specifically the science now offered at beach resorts like perhaps the White Lotus. It's true, high end resorts are diving into longevity tourism by offering wellness treatments like like full body MRIs, DNA based diets and experimental anti aging therapies. We gotta dive in. Let's take a trip to a five star resort turned high tech health center. Think the White Lotus. But with fewer scandals and more full body MRIs. This trend is called longevity tourism. And it's exactly what it sounds like. Traveling for cutting edge anti aging and health optimization treatments. We're talking full body scans, DNA based diets, IV drips and even experimental longevity therapies all wrapped up in a vacation package with a waterfront view and matching bathrobes. But what's actually backed by science here and what's just a wellness fad? Let's focus on two treatments making waves in this space. Full Body MRIs and Senolytics. First up, Full Body MRIs, a far cry from a full body massage. These have been popular among celebrities lately. MRI stands for magnetic resonance imaging. You basically lie extremely still while wearing a paper gown and listening to really loud noises. Like a construction site. Not the most glamorous, but a really important diagnostic tool. Of course. But you have to wonder why someone would want to do this on their vacation. Well, the idea is pretty appealing. You get a deep scan of your entire body, potentially catching diseases like cancer or heart conditions before symptoms even have a chance to appear. Sounds great, right? Well, yes and no. On the plus side, early detection can save lives. Earlier cancer stages typically indicate less spread of the disease. So the sooner you can detect cancer, the better survival tends to be. But here's the downside. Full body MRIs can also lead people down diagnostic rabbit holes. In fact, about 15 to 30% of all diagnostic imaging, including MRIs, contain at least one incidental finding. That means finding something besides what you are actually looking for. And that could lead to earlier prevention. Yes, but in many cases, it also causes unnecessary stress, more tests, and sometimes even invasive procedures that carry their own risks. Another systematic review found false positives where something seems concerning but ends up being nothing. To be at 16%. And right now, they come at a pretty steep price. $2,500 for a whole body scan in the US Kim Kardashian is just one celebrity influencer who's taken up trying the test. So While full body MRIs are an exciting tool, they're not a guaranteed ticket to longevity just yet. I think I would just stick to the full body massage instead. The benefits there, in terms of relaxation and just feeling good, are worth the price for me. Now let's talk about the role of senolytics in longevity research. Senolytics are a class of drugs designed to target senescent cells, which are sometimes called zombie cells. These are cells that seem to have accumulated a bunch of damage over time. They've stopped dividing, but they don't die off like they're supposed to. Instead, they just hang around, increasing inflammatory signals that can contribute to aging and play a complicated role in diseases like Alzheimer's, osteoporosis, and heart disease. Research in mice has shown that giving a regular cocktail of senolytics to naturally aged mice alleviated physical dysfunctions and helped them survive 36% longer. A first in human pilot study of senolytic therapy for Alzheimer's disease was completed in 2023, and they found that the treatment was well tolerated with only mild to moderate adverse events. So there's some progress and they're continuing their study. But right now most studies are preclinical, meaning they haven't been tested in humans. Still, there are some trials showing promise, particularly for age related diseases like osteoarthritis. But and this is a big but still in the early days. Most of these studies are small and there isn't enough data to say whether senolytics are safe or even effective for widespread use. But if you're considering hopping on a plane for a longevity treatment, it's worth remembering this is all still experimental. For now, the best science backed longevity strategies are the exercise, a healthy diet and plenty of sleep. And there's no harm in taking a little vacation for some extra de stressing. No expensive salty IV drips needed.
