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The coverage is customizable, sign up is quick and easy, and your claims are handled in as little as three seconds. Lemonade offers a package specifically for puppies and kittens. Get a'llemonade.com pet your future self will thank you. Your pet won't. They don't know what insurance is. She said that things were getting really bad. There was no fear of anything like what happened. I don't know if something snapped. I was shocked and I couldn't say anything. A doctor comes home, but not for long. I think my wife is having a stroke. An hour later, she was back at the hospital. She just left. She had this blank stare in her eyes. Three days later, she was dead. I said, she's my child. I gave birth to her. I want to know what happened to her. At first it was just a medical mystery. I'm seeing a healthy white female that for all intents and purpose should be alive to them. This was out of this world. Just couldn't make any sense out of it. But it soon became a murder mystery. She said, are you sitting down? Because once they finally discovered what killed her, the next question was, who? If he couldn't have her, no one was going to have her. I still haven't made sense of it. I still haven't made sense of it. I'm Lester Holt and this is Dateline. Here's Dennis Murphy with Lethal Weapon. The emergency room trauma team was losing her. She'd been wheeled in, glassy eyed and gasping for breath. Her heart stopped, so they had to restart her heart. And within minutes, Michelle machines were doing the breathing and blood circulation for 41 year old autumn Klein, wife, mother, medical doctor, a rising star in the field of women's neurology. A star whose light was dimming even as they tried desperately to keep her going. These are doctors who are treating trauma patients every day. This one had totally puzzled them. The woman failing in the ER. Dr. Klein was in many ways what modern Pittsburgh was all about. The gleaming downtown towers didn't need to worry anymore about grimy soot from the steel mill smokestacks along the river. The steel industry here had mostly died by the early 80s and moved overseas. Universities, technology, medicine and finance, that was the foundation of the new Pittsburgh they called the Renaissance. And Robert Ferrante and his wife, Dr. Autumn Klein, relocated from Boston, were just the kind of Renaissance minds the city was hoping to attract. Autumn's colleague, Dr. Karen Roos, she said that she loved Pittsburgh, she loved her patients, that the people of Pittsburgh were wonderful and she was so happy to be there. Autumn had always intended to be a caregiver. Her cousin, closest sisters. Sharon King remembers that even as a little girl, she administered playtime tlc. We had a doctor's office and our patients were our stuffed animals. And Dr. Autumn Klein was holding clinic hours. She was the doctor. It was an interest that took root early for Autumn and never left. Always a top of her class student in the Baltimore area, she later got her undergraduate degree in neuroscience from Amherst. Helping people was the main thing. She was just so smart, so intelligent, so thoughtful and so caring. You and your husband must have been very, very proud of her. We were Lois Kline Autumn's mom We knew that she was putting her mind on her studies and we were giving her the best education we could possibly give her, and she was taking advantage of it. Med school was a certainty. Autumn announced she was heading to Boston. Her mother worried the city's crime rate was too high. She said, I'm going to Boston University Medical School. And I said, no, you're not. And she said, yes, I am. And I said, no, you're not. And she said, yes, I am. And she went to Boston University Medical School. She had a mind of her own in medical school. Autumn developed a romantic thing for a research colleague and he for her. Robert Ferranti, Bob to his friends, held a PhD in neuroscience and was hunting for cures to devastating brain illnesses like Lou Gehrig's and Huntington's diseases. He was also more than 20 years her senior, divorced with two grown kids. I simply told her that that was a little bit too old for her. I didn't Think that that was the right age. But two days before graduation from med school, a determined Autumn, wasting no time, was walking down the aisle with her much older bridegroom. And what was your impression of him, Sharon? Nice guy, a charming guy, A bit heady, you know. Egghead. Yeah. Nerdy. Yeah. And she kind of was, and she kind of wasn't, you know. The couple made a home just outside Boston. In a few years, a baby girl arrived into their hectic lives. Autumn took it in stride. A 2am diaper change is nothing for her. She's, you know, I mean, a 2am call from the hospital. You have to come in to take care of this patient. You know, she's used to that. The new mother was becoming a sought after specialist in neurological ailments in women. Because of her expertise, she was interviewed for an educational video distributed by the Discovery Channel. Women with epilepsy really need to be started on a seizure medication in advance of pregnancy. But Autumn was growing frustrated with Boston, and professionally, she felt as though she'd crested there. That's when Pittsburgh loomed into view. In 2011, the University of Pittsburgh and its renowned sister medical center offered an ideal career move for Bob. A new research lab for Autumn, a chance to head her own department. Autumn was not just a rising star, she was a shooting star. She was nationally recognized as a leader in her field at a very young age. But still, something was gnawing at her, a kind of emotional vacuum. She wanted to have another child. By now, in her early 40s, she was taking fertility treatments, hormone injections, but nothing was happening. Was it really eating away at her that she wasn't getting pregnant? Time was going by. Yes. And you know, just speaking from experience, fertility treatments are the loneliest place a woman will ever go. Looking back, her mom Lois recognized some worrisome signs. Changes in her daughter. I kind of saw that she wasn't herself too much anymore, that she was kind of a little. What do you call it? Kind of a little down, maybe here and there. Then in early 2013, the couple tried a new approach to the baby problem. A fertility doctor thought the bodybuilding supplement known as creatine just might help Autumn get pregnant. As it turned out, her husband Bob had been using the stuff in his research. So on April 17, Autumn Klein seemed ready to give creatine a try. She texted her husband that day, I ovulate tomorrow. He answered, perfect timing. Creatine, smiley face. These are hospital security camera pictures that show Autumn throughout the day and leaving work late that night. Ten minutes later, she was Home. And minutes after that, her husband, Bob Ferranti, was on the phone to 911 with the others. Hello? Hello? Please, please, please. His wife slumped on the kitchen floor, gasping for breath. The dispatcher asked the husband what he was seeing. I think my wife is having a stroke. Paramedic Steve Mason and his partner arrived at the Ferrante home to find a woman in very bad shape. She was lying on her back on the kitchen floor. Her eyes were open and she was unresponsive. An hour after walking home from the medical center where she worked, Dr. Autumn Klein, seen here in hospital surveillance footage, was back as a gravely ill patient in its emergency room. And whatever was happening to her was a medical mystery to the team trying to keep her alive. Then they saw the blood, so neon red, so out of their experience. When we come back, Autumn is surrounded by some of the best doctors in the country. But no doctor can work miracles. To them, this was out of this world, just couldn't make any sense out of it. Maybe someone else could. Doctor Autumn Klein had been rushed by ambulance to the east of the University of Pittsburgh Medical center after slumping to the kitchen floor of her home. We thought that there was definitely a possibility of a stroke, and we knew that she was in critical condition. Now the trauma team surrounding her was trying desperately to keep her vital signs going. Alan Jennings, at the time a reporter with NBC's Pittsburgh affiliate WPXI, covered the story. He recounted what doctors later said about that night. She had this blank stare in her eyes, barely a pulse, and they didn't know what had happened to her. No, they didn't. Autumn was struggling to breathe. And then in comes the ventilator. The ventilator. The machines are now taking over, taking over to keep her alive so they could. Until they could determine what in the world was going on. At some point, Alan, do they realize that this is one of their own? This is that brilliant young doctor that works in the women's neurology unit. They did at one point. I don't know that they would have treated anyone any differently, but she was one of them, one of the team. When Autumn's husband, medical researcher Bob Ferrante, arrived in the trauma room, he tried to give the team some of his wife's medical history. He explained she'd been on fertility hormones. She had headaches, fainting spells, and that she generally was expressing that she hadn't been feeling well. He told the ER doctors he thought his wife had suffered a stroke, though diagnostic tests said otherwise. By then, Bob Ferrante had already called his father and mother in law at their home near Baltimore with the bad news. Autumn's mother, Lois Klein, said they got in the car immediately to drive through the night to Pittsburgh. She was counting out the exits. And I said, please let me get to Frederick, then please let me get to Hagerstown, please let me get to Hancock, and please let me get to Pittsburgh. Back in the er, a resident trying to rally Autumn's failing body stuck an IV into her and noticed something quite odd. Her blood in his tube showed shocking red. And the observation of that doc at the bedside that this blood is too red, why am I seeing blood this brilliantly red? Saturation to them, this was out of this world, just couldn't make any sense out of it. Eventually, Autumn went into cardiac arrest. Doctors managed to bring her back barely. They actually took turns doing chest compressions to try to get some reaction from her, to try to get her heart moving and pumping again. Another doctor reviewed Autumn's symptoms and ordered up a test. He wanted a toxicology screen of her blood. Hours passed. Her blood was being pumped into a machine that was doing the oxygenating work of her heart and lungs. At some point, word had reached her cousin Sharon, now living in Washington state. Sharon talked by phone to Autumn's frantic husband, Bob, and was grateful for his medical background. He was calling his colleagues. You know, he knows this neurologist or this person. Great, Use your resources. I had no idea what was going on. Eventually, though, Autumn lost brain function. By the time her parents finally made it to the hospital, they could see there was little hope for their daughter. They had a lot of tubes and things hooked up to her, and I held her hand and I talked to her and I told her, you heal everybody else's brain, why can't you heal your own? Sharon wanted desperately to fly out from Washington state to see Autumn, but her Aunt Lois told her to wait. That's my other half in that hospital bed. I need to be there. Doctors managed to keep Autumn alive for two full days. @ some point, Sharon could tell that Autumn's grieving husband had run out of hope. He did say to me, I'm going to go spend the last night with the love of my life. And at the time, I thought, it's not over yet. But in the ER suite, everyone knew it was Autumn's little girl was brought to her bedside. She made some comment to somebody about, I don't think Mommy's ever going to come home again. On the third day, after she'd been wheeled into the Er. Autumn's exhausted colleagues pronounced her dead and turned off the machines keeping her alive. A lot of my life feels like it doesn't make sense without her. You know, she was there for everything. Autumn's husband and family now had funeral plans to make and even darker days to get through. But one person wasn't done with the mysterious case of Autumn Clyde. His work was just getting started. Dr. Todd Lukasevic, Associate medical examiner for Allegheny county, performed the autopsy on Autumn. It was regarded as a sudden, unexpected death, which meant the county needed to figure out why this otherwise healthy woman was dead. There was no reason to suspect fertility hormones, vitamins or supplements like creatine could have led to her collapse. Her brain showed no signs of a stroke, though an examination of the heart did reveal an abnormally shaped heart valve. It's a congenital anomaly found in approximately 2% of the population. Does it lead to early death? Not in your 40s. You need to be symptomatic. At the conclusion of Autumn Klein's autopsy, the medical examiner was perplexed as to what killed this woman. I'm not seeing anything. I'm seeing a healthy white female that for all intents and purpose should be alive. On the form that asked for cause of death, Dr. Lukicevic wrote, pending no definitive answer. But in a few days time he would have more information. The blood work was back from the lab. Autumn Klein had suffered a very unnatural death. Coming up, what exactly had killed Autumn? I was shocked and I couldn't say anything. Or is the question who? When Dateline continues. Before the trophy and bragging rights are rightfully yours, before your sleeper turns in a season no one saw coming, before stats and projections turn into points on the board and your lineup falls perfectly into place, you flip the lid on a can of on nicotine pouches. And as you make your first pick, you know this is the season where fantasies going to surpass reality. It's on products for tobacco consumers 21 years of age or older. Warning, this product contains nicotine. Nicotine is an addictive chemical. Hey, Ryan Reynolds here for Mint Mobile. You know one of the perks about having four kids that you know about is actually getting a direct line to the big man up north. 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Two days after Allegheny County's associate medical examiner performed his autopsy on Autumn Klein, the phone rang. The voice on the other end was from the hospital. Autumn's blood tests were back. Dr. Todd Luckacevic was startled to hear what the lab found lethal deadly amount of cyanide. What did that tell you? That told me that I have a cause of death now. Cyanide. The poison of the Nazi death camps and the Jonestown massacre of the 70s. Lethal, fast killing stuff. Not a common cause of death. I have done approximately 3,500 cases in my career and this is my first case of cyanide poisoning. The lab's toxicology work found cyanide levels of 3.35 milligrams per liter in Autumn's blood. So this is a lot of cyanide. That's correct. Still, he needed to confirm the results with his own tests. He wanted to re examine Autumn's remains to see if he could find cyanide in other parts of her body. But by then he had released it to the funeral home. So here's an easy solution. You go back to the body and you take a second look. Would love to. When we got the phone call on Tuesday that she had a lethal level of cyanide in her blood, I called immediately the funeral home and she had already been cremated. But the ME still had samples of Autumn's blood. Its toxicology used to performed its own test for cyanide. Analyst Alicia Smith added a simple solution to the blood. If cyanide was present in the sample, it would turn the center well of this disk purple. She and Lukacevic demonstrated what they found. This example that we use today is very representative of Autumn Klein sample. It's almost identical. Sure enough, the sample changed color. Her color change was a deep kind of dark purplish pink and it was obviously positive for cyanide. Does that saturation of color tell you you got A lethal amount? Oh, yes, definitely any amount. Even the 1 milligram per liter. Even the light pink color change means there's cyanide there. A significant toxic, if not lethal, amount of cyanide present. Autumn Klein had died of cyanide poisoning. No question about it. He said he grew even more confident when he reviewed the details of how she had collapsed and suffered. Cyanide, once ingested, can quickly starve the body of oxygen. So oxygen's on the blood, but it's not being utilized by the body. It was the trapped oxygen that had turned the blood in Autumn's veins that vivid red. He also considered the 911 call. As her husband is begging for help, Autumn could be heard moaning in the background. Now she's, like, having a seizure, like she. Jesus, sweetheart. Lukas says that was likely Autumn struggling to breathe, another important sign that cyanide was in her system. He knew he had a bizarre death in his hands and immediately contacted the police. I called the detectives and I let them know cause of death is cyanide poisoning. You need to help me with the manner of death. He wanted to know if Autumn had taken her own life or been poisoned. In other words, murdered. There's a note on my desk saying that the coroner's office had a. A woman come in who had a lethal level of cyanide in her system. Cyanide poisoning? Yes. How many of those have you seen in your career? This is my first one. Soon, Autumn's mom was given the news about the blood results. She then called her niece, Sharon King, out in Washington. She said, are you sitting down? I was like, okay. And she said it was cyanide. Just like that. And I was shocked. And I couldn't say anything. I couldn't catch my breath. When Autumn's colleague, Dr. Karen Roos, heard about it, she knew right away her friend had suffered an agonizing death. As a medical professional, I know about how people die of cyanide poisoning, and I couldn't dwell on that. And just as in an old Agatha Christie cozy murder mystery about a cyanide poisoning in the village, the inspector was about to call. Pittsburgh senior investigators were en route to talk to Robert Ferrante. Did he have any idea how cyanide found its way into the bloodstream of his late wife? Coming up, a husband's theory of how and why his wife died. So what'd he say? Why would she do this to herself? What was he suggesting? And did he know something that police didn't? Five days after doctors turned off the machines on Dr. Autumn Klein. Pittsburgh police detectives made their way to the three story brick house where she made a home with her daughter and husband, medical researcher Robert Ferrante. Veteran detective Jim McGee took the lead. Ferrante greeted him and his partner. We start talking to him and what he can tell us about what happened to his wife at that point. Ferrante told the detectives how his wife had arrived home that night a little before midnight, and how she came through the door and just collapsed on the floor. Oh, God. He then recounted what he told 911. I think my wife is having a stroke. He thought his wife had suffered a stroke. The detectives informed him he was wrong about that. We asked him if he knew that his wife died of cyanide poisoning. So what did he say? He kind of gasped and said, why would she do this to herself? Why would she do that to herself? That's correct. To the cops, the man looked visibly shaken. It seemed he was suggesting his wife had died by suicide. Ferrante then told the story about Autumn trying and failing to get pregnant. He said she'd recently been taking the supplement called creatine in the hopes it would help with fertility. Veteran Detective Harry Lutton understood the late wife's emotional agony. She's trying to have another child, and that's a lot of stress on a woman when they're trying to have children and they can't have children. Could Autumn's distressed state of mind have led to suicide? Detectives had to consider that as a theory. But cyanide, that's an unusual way to kill yourself, and it's a hard to get poison. How could Autumn have gotten her hands on it? Well, we looked into the labs that, you know, where she worked. She didn't work in a lab. She worked with patients. She was a clinic doctor, right? She was working. Hands on, yes. But there were other labs at the medical complex, labs stocked with poisons, including cyanide. Maybe Autumn wandered into one of those. Detectives pulled hospital security cam footage from that last day, and here's what they saw. That's Autumn as she's getting ready to leave work. She goes up a set of escalators, disappears for roughly six minutes before coming back down and heading home. Question. In those minutes missing from the camera's eye, had she found her way into a lab with toxins? And maybe this is where she goes to get her hands on cyanide to inexplicably kill herself? That's correct. Yet there was a problem with that scenario, a big one. The investigators learned that to get into Any of those labs, Autumn would have needed a special access card. Is there any sign that she had a card swipe that put her in an area where another researcher or somebody might have had signs? No, there's no card swipes at the time that she left work. The more they dug, the less detectives believed this unexpected death was a suicide. True, Autumn was frustrated by her infertility, but disappointment was all it was. Thinks her cousin Sharon. Suicide was never on her radar. That was not Autumn. That was just not Autumn. Family, friends and colleagues agreed Autumn was a woman with plans to live, not die. She had a daughter she adored and was scheduling vacations and new research projects just before her death. So if she didn't take it and your theory is that she hasn't killed herself, the only place to go is homicide. That's correct. Who would want to murder Autumn Klein? The spouse is almost always a suspect. Till they're not. But the husband here, Bob Ferrante, was a renowned medical researcher. He didn't seem to fit the bill. Professional guy, well regarded. There don't seem to be any money issues in the household. That's true. In fact, the marriage of Ferrante and Klein appeared to outsiders to be a good one. Still, detectives had to consider the husband's line of research. He worked routinely with toxins in his lab, but not with cyanide. More than a week after they first interviewed the husband, detectives began talking to his lab assistant, associates. The people that we talked to said that there was no research with cyanide yet. Detectives were just getting started with their investigation. They combed through labs and laptops, interviewed friends and colleagues, reanalyzed hospital footage. I think once we got all that together and got all the pieces of that puzzle together, we had our picture. A picture, he said, that revealed only one person who had the motive and the means to. To kill Autumn Klein. Her husband, Bob Ferrante. Though the evidence was largely circumstantial, Three months after Autumn's death, the cops were ready to make an arrest. At the time, Bob Ferranti was visiting his sister in Florida. Pittsburgh PD Detective Lutton headed south to make the arrest, but when he got there, the sister said Ferrante was gone. She said that he got a phone call from an attorney, and he got in the car and said, I gotta go, and he left. Did you think that Dr. Ferranti was doing a runner on you? He was trying to get away? Yes. Yes. I mean, we were told that he was going to his attorney, but he's running from us. He knew we were coming on your books. He's a fugitive. Yes, but not for long. As it turned out, Ferranti was on his way back to Pittsburgh to turn himself in, says his attorney, when he was pulled over by state police, police in West Virginia, and later handed over to Pittsburgh authorities. Police had their man. Now they and the Commonwealth of Pennsylvania had to prove to 12 men and women that he was the right one. They heard a clean case. They heard a very clean case. To Jeffrey A. Manning, the judge who would preside over it all. The case against Bob Ferranti, far from a sure thing, could well leave jurors scratching their heads. And I'm not one for predicting verdicts, but I would not have predicted one here. It could have gone either way and you wouldn't have been surprised. That would be correct. Coming up, was jealousy a possible motive for murder? What had Bob Ferrante discovered about his wife? If this were somebody that she was remotely interested in, she would have told me. When DATELINE continues. Smartless Mobile Here. Did you know that 90% of your phone's data goes over WI fi? So paying for an unlimited data plan doesn't make sense. Not at all, Sean. No sense at all. But do you know what does make sense? What? Smartless Mobile. 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Kids learn to earn, save and spend wisely. And parents can rest easy knowing their kids are learning about money. With guardrails in place, sign up for Greenlight today@Greenlight.com podcast. Doctor Autumn Klein and Robert Ferranti had all the trappings of success and happiness. A nice three story home, a short drive from the heart of the city. Prestigious jobs at the University of of Pittsburgh and its medical center. At one time, it all seemed enviable. Did you think they were a good couple? Yeah. Yeah, I did. And then it all went so wrong. Autumn, dead from apparent cyanide poisoning. Her husband, now a year and a half later, standing trial for her murder. Even to the presiding judge with years on the bench, this was a first. You had a very intelligent man who's accused of poisoning his wife. You have experts who argue with one another and tip top good lawyering going on. Very good lawyering, Very good experts. And it would be up to prosecutor Lisa Pellegrini to explain what drove an otherwise mild mannered scientist to kill the wife he supposedly loved. And in such a cruel manner. She opened by describing a man, infuriated one losing control of his more successful wife, who had in turn grown tired of him. Alan Jennings in the courthouse. Reporter Alan Jennings was in the courtroom. Prosecutors say he was obsessed, jealous. His marriage. He realized he was going to be dumped by his wife. The prosecutor asserted that the marriage was in free fall at the time of her death. Autumn believed her husband had emotionally checked out, especially when it came to the issue of having another child. Child. She more or less told her cousin Sharon he was a cold fish. My husband's a psychologist. And she said, I need you to ask him if there's such a gene as for compassion. Because if there is, then Bob is lacking it. Wow, that just describes acres of sadness, doesn't it? Yeah, yeah. The prosecutor showed an email Autumn had sent her husband in the months before her death. She wrote, I realize now I have been alone, alone in this entire emotional journey. I can't even speak to you without getting angry. Did she ever say, sharon, I'm going to leave him. This isn't working? Yes, she did to me. She did to me. Yes. And he was positively rattled to the core, said the prosecutor, when he found out Autumn was texting and emailing a male colleague she'd spent time with at a conference in San Francisco. Bob Ferranti said the prosecutor suspected his wife was having an affair. Autumn's cousin was certain that wasn't true. If this were somebody that she was remotely interested in, she would have told me. So you don't think anything physical was happening? Certainly no. No. But as the prosecutors told it, the defendant believed otherwise. Rather than shoring up a crumbling marriage, the embittered scientist, his Wife, the new rising star came up with a cold, cold blooded solution. He poisoned her. The motivation? Just jealousy. That if he couldn't have her, no one was going to have her. Ferrante, the prosecutor said, thought he could get rid of his wife quickly by slipping her cyanide. When she didn't die immediately, he had to come up with a plan B to mislead the paramedics and doctors. The Prosecutor played that 911 call. I think my wife having a stroke. The prosecution was establishing Dr. Ferrante's attempts to lead everybody that he encountered, starting with the 911 operator. And he said, well, I think she's had a stroke. So steering it, steering it. Then when Autumn finally died, according to the prosecutor, Ferranti said something that he thought would keep the cause of death secret. Lois Klein testified that her son in law said flatly he did not want an autopsy. I said, I'm her mother and I want an autopsy because you wanted to know the cause of death. I said, I can't believe you don't want to know what happened to her. And his response was that people do that. They do autopsies, and then the people don't want to know the results of it. So that was that. The prosecution had described a man who'd lost control of his wife, killed her, and then tried desperately to cover it up. Defense attorneys Bill Diffenderfer and Wendy Williams. You get this picture of a jealous guy whose career is being eclipsed by his wife, thinks she's got a lover, and bang, she's dead. Well, that's the spend that Commonwealth put on this thing. And obviously we think the reality is that's not the case. They said the prosecutor's alleged motive here made for great melodrama, but it was miles away from the truth. Bob was very successful. Huntington's disease, als, on the verge of some big breakthroughs. Bob Ferrante, they countered, was a brilliant researcher and a loving man devoted to helping his wife, not hurting her. And to sell that image, they flabbergasted the courtroom by calling the defendant himself to the stand. So in this case, the defendant made that choice. I've often said that it's risky at best. The minute the defendant takes the stand, we now have the government's proof versus the defendant's credibility. A gamble his defense team said Ferrante was willing to make. He wanted jurors to see him for the man he was, one who loved his bright, complicated wife. He wanted to help the jury understand what was going on in their marriage. And you know, tell them how badly his wife wanted to have a child. Yes, he conceded he had been a jealous husband for a brief moment. But then he and Autumn had kissed and made up. In the weeks before her death, they go on a trip to Puerto Rico with their daughter, as the neighbors describe. When they come back, they're glowing, they're in love, they're holding hands. Those actions speak a thousand words. In the moments after his wife collapsed, he said he honestly thought she was having a stroke. When she died, he wanted simply to honor her wishes and donate her organs, and that's why he did not want an autopsy. He was aware that if an autopsy is done, a full autopsy is done, it will destroy the ability to donate the organs, which was his wife's request. A loving and loyal husband to the end, according to the defense, not a mad scientist treating his wife like a lab rat, killing her with cyanide. Speaking of which, they said the prosecution's claim of how Autumn died was all wrong. There is not evidence that my client had anything to do with her death, let alone her death caused by cyanide, an age old poison. Its connection to a medical researcher and his doctor wife were about to be analyzed beneath a very different kind of microscope. The unforgiving eye of the law. Coming up, would someone as smart as Robert Ferrante really use something as obvious and easy to trace as cyanide? That's like me buying a shotgun, telling everybody, hey, I just bought a shotgun, and two hours later my wife is deceased from a shotgun shot. Couldn't be that stupid. He would be the dumbest guy in the universe. The Commonwealth of Pennsylvania had tried to paint Robert Ferrante as a jealous husband driven by rage to poison his wife. How did he do it? Prosecutors believed he slipped the cyanide inside a drink and gave it to her shortly after she came home that night. A theory, said Judge Manning, that was tough to prove. No one stood there with their two eyes and said, I saw him put the cyanide in the drink and give it to. No one said that that is a weak point in the prosecution's argument. They wish they had it, but they didn't. Of course it is. But keep in mind, circumstantial evidence, even though most people don't, don't believe what it really is, is very powerful. Prosecutor Lisa Pellegrini told the court that Ferranti used his wife's vulnerability, namely her infertility, to trick her into taking cyanide that night. Earlier in the day, Autumn had sent him this Text. I ovulate tomorrow. He texted back, perfect timing. Creatine, smiley face. Creatine, creatine. This is the solution. This is it. Ferranti, the prosecutor alleged, had convinced his wife that creatine could help her get pregnant. He whipped up a poisoned drink, knowing she'd take it as soon as she came home. The poison drink theory was corroborated by something told later to a doctor friend of Ferranti. Dr. Ferrante told him, he said, I don't know. She came home, I gave her a creatine drink, she drank it and she passed out on the floor. And no one may have been the wiser for it if it hadn't been for a lab test that found a sky high amount of cyanide in Autumn's blood. Subsequent tests, the prosecutor added, were also positive for the poison. Associate Medical Examiner Dr. Todd Lakicevic underscored that for the jury. What caused this woman's death was cyanide poisoning. Period. No doubt, no doubt. Nor was there any doubt, said the prosecutor, as to who poisoned Autumn. Police discovered the defendant's laptop hidden in an office safe, and inside it, a wealth of information that told them Bob Ferrante had indeed been a very busy researcher. In the months before his wife's death, Dr. Ferrante was googling searches concerning cyanide, where to purchase it, how to purchase it, the effects on people. And he didn't stop there. The prosecutor said Bob Ferranti then made an interesting request to his lab associates, something later relayed to detectives. He goes to the purchasing person in the laboratory and he tells this person that he wants to order a bottle of cyanide. Has he ever done that before, detectives? Never. Better yet, the detectives explained, the doctor asked for the cyanide to be delivered overnight. And when is all this in relation to Autumn's slumping to the floor in her home? Two days prior. Two days prior? Yes. Ferrante, he said, had even left his fingerprint on the container, which, interestingly to them, had 8.3 grams of cyanide missing. What, like a heaping teaspoonful, maybe of cyanide? I think about a teaspoonful would be about 8 grams. Is that a lethal amount of cyanide? Yes. Prosecutor Lisa Pellegrini said the defendant thought he was so smart fooling his wife and then everyone else by using a poison he assumed was untraceable. Standing and looking at the jury points to Ferrante. That man right there was one blood test away from the perfect murder. Murder, responded the Defense. What murder, Robert Ferranti had said did not commit a crime because there was no crime. I said as forcefully as I could, we don't believe, and we will never believe that Autumn Klein died from cyanide. The defense was attacking the cornerstone of the Commonwealth's case. That blood test, with its lethal reading of cyanide, could never be trusted. It said there's no way that the result is reliable. Throw it out. Yes, because he said, the lab initially screwed up with that 3.35 calculation. It only caught its error months later, correcting the level to 2.2. A still lethal amount of cyanide in Autumn's blood. It certainly raises its a real issue of its credibility and gives the defense something to work with. Absolutely. Gave the defense a lot to work with. Far more reliable arguments, Ferrante's attorneys. Was another test done in the weeks after Autumn's death. It too found cyanide in her blood, but at very low levels, nowhere near lethal. And in this case, that alone, as Cyril Weck eloquently articulated, was more than reasonable doubt for this jury to acquit my client. The reports are highly conflicting. Dr. Cyril Weck, the defense had introduced into the legal mix a renowned Pittsburgh and internationally recognized pathologist of many years. Dr. Wecht had weighed in on cases from the JFK assassination to the deaths of Elvis Presley and JonBenet Ramsey. He told the court the conflicting tests demanded a tiebreaker. What you do is you got to send it. Then again for laboratory testing, preferably to a third highly respected toxicology lab. That was not done. More compelling, he said, was evidence of scarring around Autumn's heart, which could have triggered an electrical malfunction, stopping the organ cold only on the spot. CPR could have saved her. And in the absence of somebody hitting you in the chest, somebody knowing what they're doing with training in cardiopulmonary resuscitation, you probably will die. In other words, the defense said, Autumn could have died of natural causes. They added that crime scene techs processed the house and never did find so much as a trace of the poison. And their client cyanide. Google searches done for research purposes, not murder. I mean, here he is in January asking questions of Google about the nature of cyanide. This looks very bad. In April, he's asking about cyanide. Potassium cyanide. Neuroscience research project. The defendant further explained his actions from the stand. He ordered the poison for work and even took it out of the box when it arrived. That's why his fingerprint was on the container. Besides, his lawyer added, a man as smart as Bob Ferrante would never use a weapon that could so easily be traced back to him. That's like me buying a shotgun to telling everybody, hey, I just bought a shotgun, and two hours later my wife is deceased from a shotgun. Shotgun couldn't be that stupid. He would be the dumbest guy in the universe. In closing, the defense begged the jurors to use their common sense, which they later said is exactly what they did. Their common sense and the science presented told them Autumn Klein had died of cyanide poisoning because the defendant had given it to her. They found him guilty of first degree murder. Crushing, right? Crushing. Especially in this case. Absolutely crushing. Yep, good description. Robert Ferrante has since been sentenced to life in prison. He is challenging his conviction in court. For now, though, Autumn's family feels they've gotten justice. Their anger towards her husband has been overshadowed by all the what? Not only do I grieve Autumn and the loss that she is to me and to us as a family and to our community and our friends, but also her patients. You know, my heart breaks for her patients. It was all Dr. Autumn Klein had ever wanted to do. Help others. Now that chance is gone. Swept away way too soon. That's all for now. I'm Lester Holt. Thanks for joining us. Did you know 39% of teen drivers admit to texting while driving? Even scarier, those who text are more likely to speed and run red lights. Shockingly, 94% know it's dangerous, but do it anyway. 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