Dr. Dogris (63:06)
So we conducted a test with Mr. Sean Kelly. We have three conditions. Condition number one was baseline, where we measured his brain using a FDA cleared electroencephalogram made from the company Neurofield incorporated, called the Q21, also used an FDA cleared software called Neurofeld analysis to measure his brain. This is the result of the comparison from this test. In the first condition, we took five minutes of brainwave data just to have a baseline. Then we stopped the EEG device and we called his phone and we had him hold the phone up to his right ear for approximately five minutes. And then we ended the call, took the phone away and then started the EEG measurement again and measured five more minutes of brainwave data. Upon completing that recording, we called his phone again, but this time we played. We placed an Aries device on his phone and had him hold it up to his right ear again. And we did so for five minutes. At the end of that five minutes, we ended the call, took the phone away and then measured the brain again. It's important to note that the phone was taken away during the EEG recordings so as to ensure that there was no artifact that could distort the signal or change the data that we were measuring. So what you're seeing here is a comparison from the first exposure with no Ares device on the phone to the second exposure where there is an Ares device. So the P1 Pre is the phone with no protection, and the live call with no protection. And that's the purple line, and the green line is the phone with protection. Now, as you look at these plots, you'll notice these little spectrum. It says spectrum and FP1, FP2. These are all site locations from the EEG cap. We use the international 1020 system to identify the sites. And so you see F3, F4. The F stands for frontals. And then there's central parietal occipitals, temporals. Now, in this recording, on the horizontal axis, you'll see little black hash marks in the axis there. Any part of the axis that is painted in black represents a statistical significant difference from pre to post at the probability level set at 0.001, which is a very conservative setting to distinguish change statistically. And one of the notable things that we saw here from pre to post almost immediately is that in the 10 Hz band, which is the alpha band, there is a significant increase in alpha from pre to post. And remember, this post represents that the Aries device was present and the pre is not. So it suggests that there's obviously a huge difference here right afterwards. And typically, when somebody has an exposure to a cell phone, the same trend continues to happen. You don't see a sharp increase in alpha from pre to post in these kinds of conditions. You're also seeing some varied increases in the higher frequency bands as we look at this. So if I go through every one of the site locations, the central 3 and 4, right, left side of the. Of the head here, we have significant increases in power across the board from pre to post, suggesting that something did change here when the Aries device was placed on the phone. Now, having a good healthy amount of frontal alpha in a resting condition like this is very good. It's our idling frequency that we make when we just relax. And so a deficiency in alpha can be associated with, you know, issues like anxiety, focus, concentration issues. There can be all sorts of issues that are associated with that. Also, neurodegenerative and neurodevelopmental issues are also associated with deficiencies in Alpha. So when we look down the midline here, again every one of the plots shows this market increase. Now another way of looking at this also in the headmaps. Now the brain creates a whole bunch of different frequencies and these are speeds. Delta is in the 1-4 Hz band and represents a frequency that's very slow. Typically you make delta when you sleep, but you also make it when you're awake. All these frequencies are made all the time, but they are state dependent. So if you have an excess in delta when your eyes are open, that can create brain fog. Difficulty with concentration, attention, focus. Same with theta. So these are top down views here with the nose being in the front right ear and then left ear. And what you see here is the map on the left. Here is the phone exposure with, with no Aries present. And the second one is a phone exposure with the Aries device on the phone. The map on the right is the statistical comparison. If the electrode is colored in red, that means it met the probability cutoff of 0.001 and was significantly different from pre to post. If the electrode is in black, that means it is not significantly different at the 0.001 level. Now it might be significant at 0.01 or.05, which is still considered statistically significant. Now we set the bar pretty high here because we really want to kind of challenge and see whether or not we actually see big differences. And one of the notable changes here is that with, with the, the amount of delta here drops when the Aries device is on the phone. And it's, and it's right in the, in the frontal lobes here. You can see these electrodes here are, are colored in red there. There's a pretty significant drop in power in, in the delta band. And if you look at this legend here, what this represents is microvolts. So these are very tiny amounts of power that come out of the brain. Millions of a volt basically. And so when you, when you, if you look at the color on the legend, you can get an idea that the redder it is, the higher the power it is, the bluer it is, the lower the power. So it looks like you can see that the phone was over the right temporal lobe. And you can see that there's a pretty big difference here in the amount of delta that was produced from pre to post. When a person has their eyes open and they have phone exposure. The theta band also had this very similar type of finding here that the Ares device may have been associated with a decrease in both the Delta and theta, that was, in one way or another mitigated when the device is on the phone. Interestingly, like I noted before, the amount of alpha power goes up, and you can see that it's global. There is a global increase in alpha from pre to post here. And all these three different types of alpha that are measured, alpha 1 is 8 to 10 hertz, alpha 2 is 10 to 12 hertz, and alpha itself is the full band from 8 to 12. So when we look at this, you can see that there is a significant increase in the alpha band power for Sean when he had the Aries Tech device on the phone. Now, that's a pretty remarkable change here. And you can also see in the temporal lobe here. It appears that, you know, there's a real dropout in the power. And. And when the Aries device was on the phone, it prevented that from impacting the temporal lobe the way that we predict it would. The literature has been pretty clear that, you know, cell phone exposure over time can cause damage to the brain. And so in its damage, that's associated with the radiation that comes off the phone and the amount of heat that's generated in the brain on cellular structures that don't tolerate heat well and will die off over time from repeated exposure and long exposures. So it's pretty remarkable that in the resting state, the alpha goes up. And we see that in all the alpha bands and then in the beta bands, it's a little bit of a drop here. But again, the right temporal lobe has beta come up. Now, again, you want this to happen because beta is the frequency that allows you to focus and concentrate. If you don't have enough beta, then it's hard to have get up and go. It's hard to remain and sustain focus, concentration, and attention. Too much of it can create racing thoughts and difficulty sitting still and anxiety and stuff like that. But when you have a good balanced amount, then it's healthy and allows you to get stuff done. So when we look at this, we see again, this temporal lobe beta appears to come up as a result of the Aries device being on the phone, mitigating the radiation coming out of the phone. So that. That's a very interesting finding across the board. Okay. Okay. So here we have a screen that shows us heart rate variability. The way we calculate that is we look at the. The beat of the heart, and we look at the peak of every heartbeat, and we look at the distance between those heartbeats, and it's called the sdnn. We want to see the variability between Those heartbeats. And so the standard deviation from normal to normal beat is what's typically measured in milliseconds. The heart has four frequency bands that can be measured. There's ulf, vlf, LF and hf. The LF and HF bands have been described in the literature as being the two arms of the autonomic nervous system. The LF is sympathetic. And so that's the band that. Where you're getting up and getting going. It's your getting busy band, basically. Then you have the HF band, which is the parasympathetic band. And that band is your laying in the hammock and relaxing. Now, during this recording, Sean was just relaxing and he wasn't doing anything. He wasn't under task, so to speak. And so when he. When he did that, what you can see here is a pretty even distribution. He's a little bit more relaxed than he is sympathetic. And that's the way you should see somebody when they're. When they're relaxing. So in the next test, he held the phone up to his head for five minutes. Then we waited a minute, and then we shut off the phone, took it away from him, and we did another EEG recording and another recording of the heart. And he went from this balanced state to this state, which is obviously a big difference. His, you know, the LF sympathetic band went up significantly and the HF band dropped a little bit. Didn't change too much, but it dropped a little bit. Bit. He definitely appears to have been more activated by having the phone by his head for five minutes. Now, sympathetic activation is not a bad thing. You know, you need to be able to do that when you're getting ready to do something or need to mobilize yourself. However, if this is what's happening when you're in a passive state and you're holding a phone up to your head, may not be good for you for that to be happening. So, you know, that raises concern for me. The other thing is that his SDNN went up significantly from baseline. It popped up to 120.23 milliseconds. Normal is over 50 milliseconds. So it went up a lot. His heart became more varied and more sympathetic as compared to where he looked in baseline, where he was more relaxed like this, and his heart rate variability was 94.64. So after we did that test, that was pretty interesting, we waited a little bit and then we called his phone again, but this time we placed an Aries device on the phone and we had him hold it up to his head for five minutes and then we stopped, hung up the phone and then did another measurement and took a look. And it's really interesting here because this is what he looked like with ARES protection. Massive swing, parasympathetic swing off the chart. He got really relaxed after that phone went away with the Aries tech device on the phone which is really interesting. I would have expected the, the opposite to happen here. I would have expected increase in the LF band with continued exposure to the phone and, and, and not a flip like this into a pair of support sympathetic state. Also his SDNN went down to 74.98 and remember normal is over 50 so he, he went down towards 50 which is good. You know he is somebody that does engage in exercise. So having an STNN like this is good. Which means his heart's elastic, it can, it can handle stress, it can stretch when he needs it to. And that's what you want to have happen. Heart rate variability has been shown in the research to be associated with heart attacks. If it goes, if you have a heart rate variability less than 10 milliseconds then you're at risk for one. So obviously he is not. But this is a pretty interesting finding. So when you look at it, he's much more relaxed with the Aries device on the phone as compared to when there is no protection on phone like this. Pretty interesting stuff.
