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- [00:01]
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- [00:25]
Casual Commentator
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- [00:27]
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- [00:37]
Casual Commentator
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- [00:39]
Dr. Chapma
Cause there's always something new.
- [00:40]
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- [01:10]
Medical Expert
Whether or not you're a believer, we've all heard of the G spot. The question is, have you heard of the G shot?
- [01:18]
Dr. Chapma
What is it?
- [01:19]
Medical Expert
Well, it's sort of like, you know, fillers, plumping up the cheeks. Well, you can imagine that's what's happening in a different part of the anatomy.
- [01:28]
Casual Commentator
We do not personally offer the G shot because it is our understanding and it is clinically proven that the G spot is a very shady area. I really think there is something where there probably is a large placebo effect to this. A lot of the women that I've injected, some women come in and say, oh, my God, it's the best thing that's ever happened. I have some women that come and be like, didn't feel much of a difference. I don't know.
- [01:50]
Dr. Chapma
All right, so this is a clip that's available online. It's called the G shot for the G spot. Now, okay, I gotta watch this line very carefully here because this idea is nothing new. If y' all remember from a while back, like, over a decade ago, there was a TV show that actually introduced this to the masses. It was Dr. 90210, not a sponsor. So on that show, a plastic surgeon would kind of endorse and propagate this idea of G spot amplification. This physician would inject collagen into the anterior vaginal wall about 3 cm from the urethral meatus or from the vaginal cervical reflection. The point is kind of in that middle part of the anterior vaginal wall. Ish area. Okay. And this became very popular, even though the science was a little unclear and there was no published guidance for this. All right, so this goes back to some time now, that clip that we just shared is by a plastic surgeon. So I have no issues with, you know, if it's people who do a lot of cross territories in terms of our care. But I'd feel more comfortable if this was maybe a urogynecologist, obviously if it was a, a gynecologist, a urologist even, but this was a plastic surgeon. Now why do plastic surgeons like on Dr. 90210, why are they the ones this. Well, it's very easy. They're used to injecting things in areas like fillers. All right, so this is exactly where this comes from. So this is nothing new. What is new is that we're still talking about it because in the middle of March, 2026, there's a brand new publication. It's actually an RCT, though it's a very small number. It's an RCT that looks at this very issue of G spot injection. Okay. Though they don't call it the G spot, they steer clear of that whole controversy. So there is a brand new publication that comes out of different sites, the authors out of different locations in the Green Journal, okay, the title is Vaginal Injection of Platelet Rich Plasma for Sexual Function. Vaginal Injection of Platelet Rich Plasma or PRP for Sexual Function. And it's got some big people in this. I mean, Barbie Garcia is in this. Cheryl Iglesia, who's a pillar in kind of vaginal surgery. So it's got big names to this. I don't know where this is going to go. Okay, so we've been on the road of platelet rich plasma PRP for some time and we have episodes that talk about that. And there's things that it shows promise for and things that it's just kind of the wild, wild West. Now, to be clear, Platelet rich plasma, as of right now, there is no formal and FDA approved indication to use these things. These are mainly all done off label, but they seem to work in certain dental surgeries. That's the thing. It's been a thing for a long time in certain musculoskeletal conditions like lateral epicondylitis, plantar fasciitis. This thing seems to have some data. Even in osteoarthritis, it seems to work. The problem is you got to keep getting some injections because nobody knows if you just need one, if you need four, if you need five. And the difficulty, because this is all autologous, right? They draw it from your blood, they spin it and they get Platelet rich plasma is that it has to be unified and standardized. And right now you just can't order from a company your little vials of prp. I guess you can kind of bootleg it, but there's no formal FDA approval for specific clinical conditions. Okay, same thing. In gynecology. There is data where this has shown some work in quote unquote vaginal rejuvenation. I said it. I know it's controversial and you know, I'm just going to leave it as that. Also in some vulvar dermatoses, this has shown some promise like for lichen sclerosis and it's shown some promise with premature ovarian insufficiency for patients especially who are trying to get a window of time for conception. Injected into the ovary, platelet rich plasma has shown some. Not great, but it has shown some, some promise. However, injecting anything into the ovary, even a little bit of saline because of the regenerative. The regenerative and the healing properties of the ovary, that has seemed to help as well. So it's very unclear. Okay, My point is platelet rich plasma PRP as a vaginal G spot injection is now back in press. So this has been over. I mean it's over a decade. Dr. 902 weno again brought thing to the masses. And so we're going to talk about this brand new Study published on March 19, 2026 by some wonderful people. Wonderful people. I don't know if this is going to go anywhere but good water cooler discussion. And if somebody comes to your office and says hey, I read in some Vogue magazine because that's so medical, the you can inject my G spot and it's going to be lights out, baby. Well, let's talk about it. We'll be right back. This is Dr. Chapma's OBGYN no Spin podcast. All right, so first off the bat, I do respect these authors, good for them thinking outside the box. But it's a small rct, definitely not ready for commercialization and it's not going to be widely adopted as of right now. But you do what you want to do. And I find this interesting that the term platelet rich plasma. Think about that. Platelet rich plasma. So the idea is there's a lot of platelets in it was never meant to be taken outside of its original intention. And its original target back in the 1970s when the term platelet rich plasma was first used by hematologists in order to treat a platelet poor condition. Since it's platelet rich Plasma? Yeah, it was a treatment for thrombocytopenia. So from that in the 1970s, we jump about 20 years to the 1990s. And now we get this application outside of that, mainly in dental and maxillofacial surgery, where it was found to kind of increase angiogenesis, collagen, lay down, and kind of natural healing. So there is some history to this. The problem is that right now the football field doesn't have any end zones and it has no foul lines. Right. I mean, it's just kind of open space and there's people running amok. And so we need a lot more direction on this. Again, the big issue here is because it's autologous, who qualifies for this? How do we standardize this preparation? How do we standardize the amount of mls that are used for this? And this would require, you know, large scale clinical investigation. This is a small study. Again, it's even the author's aids a pilot. It's a single center, it's single blind, and it only included in the treatment group 26 patients. 26. Now, there was a control of the same number. So 26 times two is your total RCT volume. All right, so it was 52 participants. 26 had autologous platelet rich plasma and 26 had control. Now, these were all injected into the anterior vaginal wall about 3 cm or so from the urethra meatus in that anterior wall space. Now, let's just talk about that as basic anatomy for a bit. Yes, that is the kind of controversial G spot location, although it makes a lot of sense anat it makes a lot of sense in homology, in the homologous parts of the male. That is a very sensitive area, the anterior vaginal wall, especially with continual, you know, kind of a stroking pressure, because it also sits around the trigone area where some patients, some women may get that kind of urge or sensation to void. And that's where you get the little squirting phenomenon which we have covered on this episode as well. Is that pee or is that an ejaculate type of fluid? I've covered that on this episode. It's been at at least two years that we covered that. So we've discussed that kind of phenomenon. Whether that's learned behavior, you train to do that, or it's a physiologic anatomical response. Okay, so the point is, anterior vaginal wall seems to be where it's at. Posterior vaginal wall, not so much. Anterior vaginal wall. Yes. Also because of the structure of the clitoris, which we now know is not just a little structure at the top of the vagina, it is a wishbone shape that includes the encapsulation of the introitus. And so anything that puts pressure on the vaginal wall could, you know, stimulate the clitorovaginal vestibular system. So the anterior vaginal wall absolutely is considered an erogenous zone. So the idea of anything that can plump that area up as Dr. 90210 did with collagen, or bring natural healing to this with platelet rich plasma, that's the idea. Okay.
- [11:18]
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- [11:37]
Ebglis Medical Information Speaker
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- [12:11]
Ebglis Advertiser
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- [12:19]
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- [12:50]
Dr. Chapma
Let's call Out a couple of things here, not issues. I'm just saying a couple of things here that the patients that were recruited were like, hey, do you want to do this? Because let's try it. Even though here it is, you have no baseline severe sexual dysfunction. All right, so that was, that's the catch here. These were patients from 18 to 50 years of age, quote, without severe sexual dysfunction, end quote. So take it for what it is right now. They did use a scale called the Female Sexual Function Index, the fsfi, which I've actually got something published on that as well. Back in 2020 we published out of the Journal of American College Health. As you all know, I'm the OB GYN for one of a major university in Texas. I'm very proud of that. We have a big team who helps run that office and we cover the prevalence of female sexual dysfunction among college age women who present to a university medical center. We presented that in 2020 and we use the same scale. Right. We also did that with one than pre med students who got her name on this publication. Well, anyway, this brings us back to this publication that used that same scale, Female Sexual Function Index. So these patients said, yeah, sure, I'll try it again. Age 18 to 50, no severe sexual dysfunction at baseline. And then they injected the anterior vaginal wall again, that distal anterior vaginal wall about 3 centimeters from the meatus, and then followed patients up for six months. Okay, so the primary outcome was a change in FSFI at six weeks, but they were followed all the way for six months. And they also tracked some adverse issues. Now, even though, let me just say this now for the adverse event issue. While there was no serious adverse reports, events reported, this has the potential to maybe if you inject too much and it's a bulk former to lead to some urinary hesitancy, some urinary obstruction. If you go too deep, you might hit the bladder neck. So you gotta be careful of that. I mean we don't want to give. This is. We're not trying to do a treatment for Sui as a bulking agent with this either. And this is a bit more distal than where you would inject the bladder neck through the vaginal wall. But the idea remains that you gotta. This isn't all just, you know, carefree and without any. Some potential risks. There's also the potential for of course, hematoma formation and for hesitancy. I mean there's something kind of messing with your urethra that has been reported in other trials. It was not in this publication, right? So again, very small 52 participants. Let me just tell you what they found because it opens the door to discussion. And this is a true study where beauty is in the eye of the beholder. All right? Because results are like, okay. I mean, they're not like, wow, this is amazing. I'm gonna go, I'm gonna find myself a mountaintop and I'm gonna yell this from there. It's not that, but it opens up the discussion. All right, so let me just give you this very quickly. So first of all, 52 participants were randomized. 26, of course, in the treatment, 26 to the control. So here it is. Quote the median total FSFI score showed a greater increase at six weeks and six months after injection compared with women in a control group. You're like, okay, hey, something seems to be working. It does, however. So watch this. I'm going to give you the numbers here for a minute. Women treated with PRP demonstrated improvement in the FSFI subscale scores for desire, which is kind of weird because desire is much more tentorial, much more cerebral, much more interpersonal than just what's going on in your vagina. But whatever. FSFI subscales for desire, for arousal, lubrication, and orgasm. Now, orgasm makes sense because of that anterior wall stimulation. How that affected lubrication, arousal, desire is unclear, except if you think you're going to have a better chance at achieving orgasm, you're more likely to have arousal, hence lubrication. So the point is, of all those issues that were found to slightly improve desire, arousal, lubrication, and orgasm, orgasm makes the most sense. However, watch this. It's in the results section. I'm not, you know, trying to throw this under the bus or anything. Quote Although these changes were not statistically significantly different compared to control, end quote. And I've talked about this before, that statistical significance is just math. And it could be because this was only 26 patients, but there was no statistical difference in that. So the scores looked a little bit better, but it really didn't make any statistical difference. Is that clinically different? You know, again, beauties in the eye of the beholder. Quote the percentage of participants reported an improvement in their sexual function based on the patient global impression of improvement. In other words, how is it overall, that score was higher in the PRP group at six weeks and at six months compared to control. So, you know, it is what it is. Now, these patients had no baseline sexual dysfunction. They're like, hey, they can get a little better. Why not so no baseline dysfunction, only a 26 in the treatment group and 26 in the control, but it is an RCT. And again, the changes showed improvement in the FS of I subscales, but they weren't statistically significant. It's an interesting conversation. Is this the end of this kind of topic? Absolutely not. I know that there's other trials going on with this, and until this is reproduced in a bigger scale, you know, you can do whatever you want to off scale, you know, off label, as long as the patient understands it's kind of experimental at this point. Go with it if you choose to do that. I will not. But just to know that once again, is this not odd? How many times have we said there's nothing new under the sun, guys? Dr. 90210. Over a decade ago, with a G spot amplification, you started injecting collagen into the vagina. And even medical groups were like, hey, hey, hey, guys, wait a minute. This is not evidence based. We don't have any protocols for this. Injecting collagen has some potential for urethral obstruction. So, you know, we're not endorsing, we're not part of this thing. But it's interesting how time circles back to the original. This data was actually first presented at Oggs at the American European Society in the end of 2025. That was when it was in Vancouver, British Columbia, Canada. And now again it's here as a publication. So this was original research coming out of the Green Journal that just got out in print on March 19, 2026. Vaginal injection of platelet rich plasma for sexual function. I don't know. Hey, you. Do you, whatever you want to do. I'm just saying with an N of 26 in the treatment group, maybe need a little bit more data because the FSFI overall showed no statistical differences in their subgroups. But you know, it's interesting. Podcast family, now that we've done all that, I think we've met our function here. Get it? Our function. We were talking about sexual function. Oh, my goodness, Michael, this just shuts this thing off. Let's take it home. This is Dr. Chapma's ob gyn, no spin podcast.
- [20:22]
Nordstrom Rack Advertiser
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