Christina Applegate has always had a dark sense of humor. And she leans on it big time to deal with a series of enormous obstacles and challenges. As a child star-turned-household name (thanks to 11 seasons on “Married...with Children”) Christina avoids the pitfalls of other kid actors and becomes one of Hollywood’s leading ladies of comedy. She’s riding high on the heels of an Emmy-winning turn on “Friends,” and a successful string of movies (“Anchorman: The Legend of Ron Burgundy,” “Vacation”). But when she begins to develop serious and mysterious symptoms on the set of her Netflix show, “Dead to Me,” Christina’s health takes a devastating turn. And her dark sense of humor is put to the test like never before.

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Christina Applegate: Survival of the Funniest | 272