
Learn about the process that made modern science
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Gary Arndt
The modern world is built on science. Today there are millions of scientists all over the world doing research in thousands of different fields and specializations. All of these researchers are to some degree using a system that was developed over the course of centuries, a methodology that allows for the discovery of scientific truth. It isn't perfect, but it ushered in a scientific revolution and helped create the modern world that we live in today. Learn more about the scientific method, what it is, and how it developed on this episode of Everything Everywhere Daily. This podcast is brought to you in part by Stash. Are you still putting off savings and investing because you'll get to it someday? Stash turns someday into today Stash isn't just an investing app. It's a registered investment advisor that combines automated investing with dependable financial strategies to help you reach your goals faster. They'll provide you with personalized advice on what to invest in based on your goals. Or if you just want to sit back and watch your money go to work, you can opt in to their award winning expert managed portfolio that picks stocks for you. Stash has helped millions of Americans reach their financial goals and starts at just $3 per month. Don't let your savings sit around, make them work harder for you. Go to git.stash.com everything to see how you can receive $25 towards your first stock purchase and to view important disclosures. That's git.stash.com everything paid non client endorsement, not representative of all clients and not a guarantee. Investment advisory service is offered by Stash Investments LLC and SEC Registered Investment Advisor. Investing involves risk offer is subject to T's and C's.
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Gary Arndt
The scientific method is one of humanity's greatest achievements. Yet it really isn't an invention, nor is it a discovery. The scientific method is a systematic approach to understanding the natural world through observation, hypothesis formation, experimentation and analysis. It represents humanity's most powerful tool for gathering reliable knowledge about the universe, allowing us to move beyond speculation and develop evidence based understanding. The scientific method isn't perfect and it doesn't work in every situation. More on that in a bit, but it is the Best framework we have for determining the truth of things in the natural world. Depending on what source you use, you will see five, six, or maybe even seven steps in the scientific method. All of the various ways of describing the scientific method are pretty much the same, with some steps combined or some extra ones added. For the purpose of this episode, the steps in the scientific method Observation, questioning, hypothesis building, experimentation, analysis and conclusion. To illustrate how it works, I'll use one of the most famous cases ever. Alexander Fleming's discovery of penicillin. In 1928, Fleming was studying the staphylococcus bacteria, which causes infections, and one day he noticed something unusual. A mold, later identified as Penicillum notatum, had accidentally contaminated one of his petri dishes and the bacteria around it had been killed. This was the first step in the scientific method observation. Fleming had to actually take notice of what happened. And that sounds trivial, but there are countless things that can easily be overlooked. In Fleming's case, perhaps the absence of bacterial growth is pretty obvious, but it isn't always so, depending on what it is you're doing. The second step is also pretty simple. Fleming had to ask himself, why? Why did the bacteria die around the mold? Maybe when the mold contaminated the sample, it was at a different temperature, or maybe it had been contaminated by an outside chemical and it wasn't the mold itself that killed the bacteria. Once the question was asked, it was necessary to come up with a hypothesis. While all the things I just mentioned could have been true, it wasn't the most obvious reason. The hypothesis that Fleming proposed was that there was something in the mold that killed off the bacteria. The next step was to test the hypothesis with an experiment. To test his experiment that the mold produced a substance capable of killing bacteria, Alexander Fleming conducted a series of experiments in which he isolated the mold from the contaminated petri dish and allowed it to grow in a controlled environment. He then collected the fluid surrounding the mold, not the mold itself, which he suspected contained the antibacterial substance. Fleming applied this mold extract to cultures of various harmful bacteria, including staphylococcus, and observed that the bacteria were inhibited or destroyed in the areas where the extract was present. He also tested the substance with other cells, such as animal cells, and found that it didn't harm these cells. The next step was compiling and analyzing the data he collected from his experiment. Having gone through the data, he reached the final step and made a there was something in the mold that killed the bacteria. These results confirmed his hypothesis that the mold secreted a power pole. Antibacterial agent, and he called it penicillin. This process sounds pretty simple and common sense, yet it was something that took centuries to develop. Ancient people did have systemized ways of learning. Ancient China and India contributed to the development of the scientific method through their emphasis on observation, practical experimentation, and logical reasoning. In China, advancements in fields like medicine, astronomy and engineering were driven by careful empirical study and innovation, such as detailed records of celestial events and invention of tools like the compass and the seismograph. Similarly, ancient Indian scholars made major contributions in mathematics, astronomy and medicine using systematic observations, classification, and logical analysis. Likewise, the Babylonians and Egyptian civilizations practiced empirical observation for practical tasks like medicine and astronomy, but without any formal methodology. Early ancient civilizations like India, China, Babylon and Egypt were not practicing the scientific method as we know it today because their approaches to understanding the world were largely based on practical experience, tradition, and spiritual or religious beliefs rather than systematic experimentation and hypothesis testing. While they made significant observations and developed advanced technologies, their methods lacked the structured process of forming testable hypotheses, conducting controlled experiments, and analyzing results. Object knowledge was often passed down through authoritative texts or oral traditions, and the explanations for natural phenomenon were frequently tied to mythology or divine influence. The ancient civilization that saw major advances towards developing the scientific method was the Greeks. The ancient Greeks made significant advancements towards the development of the scientific method by shifting the focus of inquiry from mythological explanations to rational thought and natural causes. Philosophers like Thales and Axinamander began to propose that natural phenomena could be explained by underlying principles rather than the actions of the gods. Pythagoras introduced the idea that mathematics could reveal truth about the universe, laying the groundwork for scientific reasoning. Plato emphasized deductive reasoning and abstract ideals, although he devalued sensory experience, while his student Aristotle took a more empirical approach, advocating for careful observation, classification, and logical reasoning. Aristotle's method of systematic inquiry and emphasis on cause and effect relationships brought science closer to a structured method of investigation, even if it still lacked experimentation in the modern sense. Overall, the Greeks contributed foundational ideas about logic, evidence and the pursuit of knowledge through reason, core elements that would later evolve into the scientific method. Now, in most episodes, when I'm talking about the development of something, I usually talk about the Romans after I talk about the Greeks. However, in this case, the Romans did absolutely nothing. In this department, the group that really took up the mantle of the Greeks were the Muslim scholars during the Islamic Golden Age. During the Islamic Golden Age, Muslim scholars made crucial advancements towards the development of the scientific method by emphasizing observation, experimentation, and critical thinking. In Their pursuit of knowledge. Building on the works of the Greeks and other ancient civilizations, they translated and preserved classic texts while also improving and challenging them through original research. Scholars like Ibn Al Haytham played a pivotal role in shaping experimental science. In his book the Book of Optics, he outlined a systematic approach that involved observation, forming hypotheses, testing through controlled experiments and and drawing conclusions very closely resembling the modern scientific method. Muslim thinkers also stressed the importance of skepticism and verification, insisting that conclusions should be based on evidence rather than tradition or authority. Fields such as medicine, astronomy, chemistry and mathematics flourished as scholars conducted detailed experiments, recorded their findings meticulously, and developed theories grounded in empirical observation. Their approach marked a shift from purely philosophical reasoning, like the Greeks, to a methodical, evidence based investigation of the natural world. During the same period in Europe, scholars such as Roger Bacon emphasized the importance of empirical observation and experimentation, arguing that knowledge should be derived from experience rather than solely from accepted authorities. Universities emerged as centers of learning where logic and debate were practiced, helping to refine methods of reasoning and analysis. While experimentation was still limited and often intertwined with religious beliefs, the period saw a growing emphasis on critical thinking, systematic observation, and the questioning of established ideas. During the scientific revolution, which spanned the 16th to 17th centuries, the scientific method underwent a major transformation as thinkers began to reject reliance on tradition and authority in favor of direct observation, experimentation and logical reasoning. Francis Bacon promoted inductive reasoning, encouraging science to gather data through careful observation and then building general theories from specific facts. Rene Descartes, on the other hand, emphasized deductive reasoning and mathematical logic as a path to certain knowledge. Moving into the 19th and 20th centuries, some philosophers of science began to think about the scientific method much more explicitly. Karl Popper and Thomas Kuhn made influential contributions to the philosophy of science by offering different perspectives on how scientific knowledge progresses and how the scientific method operates. Karl Popper emphasized the importance of falsifiability, the idea that for a theory to be scientific, it must be testable and able to be proven wrong. He argued that science advances not by confirming hypotheses per se, but by rigorously attempting to refute them. According to Popper, a good scientific theory makes bold predictions and stands up to repeated attempts at falsification, which strengthens its credibility. In contrast, Thomas Kuhn introduced the concept of paradigm shifts in his work the Structure of Scientific Revolutions. He argued that science does not progress in a steady cumulative way, but rather through periods of normal science followed by revolutionary changes. During normal science, researchers work within an accepted framework or paradigm. When enough anomalies build up that the Current paradigm can't explain something. A scientific revolution occurs and a new paradigm replaces the old one. Kuhn's view challenged the idea of linear scientific progress and highlighted the role of social and historical context in shaping scientific discovery. Together, Popper and Kuhn expanded our understanding of how science works, not just through experiments and data, but through philosophical and cultural processes as well. Earlier in the episode, I mentioned that you can't always use the textbook version of the scientific method that I gave, and now you might be wondering why not. It has to do with the ability to do experiments. In fields like astronomy, you can't really do experiments. You can make observations and create hypotheses, but it is impossible to conduct experiments most of the time. For example, if you have a hypothesis on the formation of galaxies, you can't go and make a galaxy to test your hypothesis. The only thing you can do is make more observations to see if they fit your hypothesis or to see if they falsify your hypothesis. The reason why astronomers want bigger and bigger telescopes is that they want to push the limit of what type of observations are possible. Sometimes experiments aren't possible due to ethics, budget or logistics. When evidence is gathered in the field of nutrition, for example, there usually aren't controlled experiments that are conducted, although sometimes there are. They usually conduct epidemiological studies where they survey a large number of people. The problem with these studies is that they rely on statistics to glean information out of the data. At that point, your conclusion will rest on what statistical analysis you run and and how you interpret it. Another item that's often added as a requirement to the scientific method is replicability. It isn't enough for one scientist to conduct an experiment. It's necessary for everyone to be able to repeat the same experiment and get the same results. This has been a huge problem in many fields, particularly in fields that study humans, such as psychology and medicine, where many studies simply cannot be replicated by anyone else. Most people think that when a research paper is submitted to a journal, the process of peer review checks to see if an experiment works. And that is not at all what peer review does. In some fields, the inability to replicate experiments has been dubbed the replication crisis. Problems with peer review, academic publishing and the replication crisis will be addressed in future episodes. The scientific method isn't a hyper strict checklist that is followed on every single scientific inquiry. Rather, it's more of a way of thinking that allows you to approach scientific inquiry in such a way as to increase the odds that when you find something to be true, it is in fact, actually true. The executive producer of Everything Everywhere Daily is Charles Daniel. The associate producers are Austin Oakton and Cameron Kieffer. I want to thank everyone who supports the show over on Patreon. Your support helps make this podcast possible. I'd also like to thank all the members of the Everything Everywhere community who are active on the Facebook group and the Discord server. If you'd like to join in the discussion, there are links to both in the show notes and as always, if you leave a review or send me a boostogram, you too can have it read on the show.
Everything Everywhere Daily: The Scientific Method
Episode: The Scientific Method
Release Date: March 29, 2025
Host: Gary Arndt | Glassbox Media
In the episode titled "The Scientific Method," host Gary Arndt delves into the foundational framework that underpins modern scientific inquiry. Arndt explores the origins, evolution, and practical applications of the scientific method, illustrating its pivotal role in shaping our understanding of the natural world. This episode is a comprehensive guide for intellectually curious listeners, offering insights into how systematic investigation leads to scientific truths.
Arndt begins by emphasizing the significance of the scientific method as humanity's most powerful tool for acquiring reliable knowledge. He states:
"The scientific method represents humanity's most powerful tool for gathering reliable knowledge about the universe, allowing us to move beyond speculation and develop evidence-based understanding."
(00:00)
He outlines the core steps of the scientific method used in this episode:
These steps form a cyclical process that facilitates continual refinement of scientific knowledge.
Arndt traces the roots of the scientific method back to ancient civilizations, highlighting the contributions of China and India. He notes that:
"Ancient China and India contributed to the development of the scientific method through their emphasis on observation, practical experimentation, and logical reasoning."
(05:45)
However, he clarifies that these early practices lacked the structured process of forming testable hypotheses and conducting controlled experiments, which are hallmarks of the modern scientific method.
The narrative progresses to ancient Greece, where philosophers began shifting inquiry from mythological explanations to rational thought. Arndt credits thinkers like Thales, Anaximander, and Aristotle for laying the groundwork:
"Aristotle's method of systematic inquiry and emphasis on cause and effect relationships brought science closer to a structured method of investigation."
(12:30)
During the Islamic Golden Age, Muslim scholars significantly advanced the scientific method by emphasizing observation, experimentation, and critical thinking. Arndt highlights Ibn Al-Haytham's work:
"In his book, the Book of Optics, he outlined a systematic approach that involved observation, forming hypotheses, testing through controlled experiments, and drawing conclusions very closely resembling the modern scientific method."
(20:10)
These scholars not only preserved Greek texts but also enhanced and challenged them, fostering a more rigorous scientific approach.
The episode transitions to the Scientific Revolution of the 16th and 17th centuries, a period marked by a dramatic transformation in scientific thought. Figures like Francis Bacon and Rene Descartes are discussed:
"Francis Bacon promoted inductive reasoning, encouraging science to gather data through careful observation and then building general theories from specific facts."
(25:50)
"Rene Descartes emphasized deductive reasoning and mathematical logic as a path to certain knowledge."
(26:15)
These contributions solidified the scientific method's role in challenging traditional beliefs and establishing empirical investigation as the cornerstone of scientific progress.
To illustrate the scientific method in action, Arndt presents the landmark discovery of penicillin by Alexander Fleming in 1928. He meticulously walks through each step:
Observation: Fleming noticed that a mold, Penicillium notatum, had contaminated his petri dish, killing surrounding Staphylococcus bacteria.
"This was the first step in the scientific method—observation."
(08:45)
Questioning: He wondered why the bacteria were dying, considering factors like temperature or chemical contamination.
"Fleming had to ask himself, why did the bacteria die around the mold?"
(09:15)
Hypothesis Building: He hypothesized that the mold produced a substance that killed bacteria.
"The hypothesis that Fleming proposed was that there was something in the mold that killed off the bacteria."
(10:20)
Experimentation: Fleming isolated the mold, cultured it, and extracted the fluid surrounding it. He then tested this extract on various bacteria, observing inhibition of growth.
"He applied this mold extract to cultures of various harmful bacteria and observed that the bacteria were inhibited or destroyed."
(12:00)
Analysis: Through careful examination of his data, Fleming confirmed that the mold secreted an antibacterial agent, later named penicillin.
"These results confirmed his hypothesis that the mold secreted an antibacterial agent, and he called it penicillin."
(13:30)
This case study exemplifies how the scientific method leads to groundbreaking discoveries by following a structured approach to problem-solving.
Arndt discusses contemporary interpretations and challenges associated with the scientific method, referencing influential philosophers Karl Popper and Thomas Kuhn:
Popper's philosophy centers on the concept of falsifiability:
"For a theory to be scientific, it must be testable and able to be proven wrong."
(30:25)
Popper argued that science advances through the rigorous testing and potential refutation of hypotheses rather than mere confirmation.
Kuhn introduced the idea of paradigm shifts, suggesting that scientific progress occurs through revolutionary changes rather than linear advancement:
"Science does not progress in a steady cumulative way, but rather through periods of normal science followed by revolutionary changes."
(32:10)
He emphasized the role of social and historical contexts in shaping scientific discovery, challenging the notion of continuous, incremental progress.
Arndt acknowledges that the scientific method is not a rigid checklist but a flexible framework that adapts to various disciplines:
Astronomy: Experiments are often impossible; scientists rely on observations and hypotheses.
"If you have a hypothesis on the formation of galaxies, you can't go and make a galaxy to test your hypothesis."
(34:50)
Nutrition: Ethical, budgetary, and logistical constraints often prevent controlled experiments, leading to reliance on epidemiological studies and statistical analysis.
"Your conclusion will rest on what statistical analysis you run and how you interpret it."
(35:30)
Replicability is a cornerstone of the scientific method, ensuring that results are consistent and reliable. However, Arndt points out ongoing challenges:
"Inability to replicate experiments has been dubbed the replication crisis."
(36:20)
He mentions that issues with peer review and academic publishing contribute to this crisis, particularly in fields like psychology and medicine. Although these challenges are significant, Arndt hints at addressing them in future episodes.
Gary Arndt wraps up the episode by reiterating that the scientific method is a versatile and robust framework for scientific inquiry. It is not infallible but remains our best tool for discerning truth in the natural world. The adaptability of the scientific method allows it to evolve alongside scientific advancements, maintaining its relevance across various disciplines.
"The scientific method isn't a hyper strict checklist that is followed on every single scientific inquiry. Rather, it's more of a way of thinking that allows you to approach scientific inquiry in such a way as to increase the odds that when you find something to be true, it is in fact, actually true."
(38:10)
Arndt extends gratitude to the show's team and supporters:
He encourages listeners to join discussions and support the podcast through reviews and financial contributions.
On the Power of the Scientific Method:
"The scientific method represents humanity's most powerful tool for gathering reliable knowledge about the universe, allowing us to move beyond speculation and develop evidence-based understanding."
(00:00)
On Observation in Fleming's Discovery:
"This was the first step in the scientific method—observation."
(08:45)
On Popper's Falsifiability:
"For a theory to be scientific, it must be testable and able to be proven wrong."
(30:25)
On Paradigm Shifts:
"Science does not progress in a steady cumulative way, but rather through periods of normal science followed by revolutionary changes."
(32:10)
On the Flexibility of the Scientific Method:
"The scientific method isn't a hyper strict checklist that is followed on every single scientific inquiry. Rather, it's more of a way of thinking that allows you to approach scientific inquiry in such a way as to increase the odds that when you find something to be true, it is in fact, actually true."
(38:10)
"The Scientific Method" episode of Everything Everywhere Daily offers a thorough exploration of how systematic inquiry has evolved and continues to drive scientific progress. By blending historical context with contemporary challenges, Gary Arndt provides listeners with a nuanced understanding of the scientific method's role in uncovering the truths of our universe.
For those seeking to deepen their knowledge about scientific processes and their implications, this episode serves as an invaluable resource, highlighting the enduring importance of observation, experimentation, and critical thinking in the pursuit of knowledge.