Join our Week 1 DFS game! https://www.draftkings.com/contest/draftteam/181506349 The crew is back and ready for kickoff! Sia Nejad, Meg Shoup and Mike McClure break down every game on the Week 1 main slate ahead of the 2025 NFL Season. (2:00) Welcome to Week 1!

(4:44) Steelers at Jets

(7:19) Dolphins at Colts

(13:40) Panthers at Jaguars

(21:44) Giants at Commanders

(28:46) Bengals at Browns

(32:58) Raiders at Patriots

(33:44) Cardinals at Saints

(37:22) Buccaneers at Falcons

(42:40) Titans at Broncos

(44:12) 49ers at Seahawks

(48:48) Lions at Packers

(53:59) Texans at Rams

(58:30) Meg's Cheat Sheet

(1:00:14) Sia's Cheat Sheet

(1:01:10) Mike's Top 3 at each Position

(1:05:40) Tips for Week 1 lineup building

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