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First Things THRST
E130 - Everything You Need To Know About Peptides For Fat Loss, Muscle & Longevity
01:18:13
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- [00:00]
A
It's not the peptide, it's the individual. I think the worst things I've seen personally, I've got a lot of horror stories from doctors and what have you, but from clients I work with. He's a functional medicine coach, therapeutic nutritionist and a peptide therapy specialist. Dean Henry. I work with healthy people to make them healthier. Longevity, anti aging prevention. I help people understand more about peptides and the education that I've learned for them to go on as a guide. Peptides are made of these 20amino acids that are found in the body. Essential, non essential. They're sequenced in in different ways, have a different objective or target area. We see a real safety profile with peptides and then you get these people, these doctors all over social media trying to monetize from peptides and say, well these have got popular. And then some of the protocols that I'm seeing from them, really, really worrying.
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B
I'm the typical guy who's going to the gym. I want to improve my body composition, I want to have more energy, feel better, look better.
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A
Very popular protocol is what are the
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B
red flags and things that you should be aware of when people are talking about peptides?
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A
There's a few variations that I think. Firstly,
- [00:58]
B
quick pause. Guys, I need to tell you something. It's that time of the year where everyone's on the winter arc hype, where they're building their physique which they plan to reveal at some point in the summer of 2026. But I hate to be the guy that says it, most of you are going to end up getting fat. You'll be overeating, you'll be following some sort of a program which isn't actually going to be getting your results. You're going to be improvising on the spot. No doubt. You won't be tracking, there'll be no structure, just random exercises with minimal progress seen on a week to week basis. Pretty frustrating, right? Well, that's the whole reason why I built the first app to help busy people like yourself find a system they can actually stick to over a long period of time. We have thousands of transformations for men and women who just plug into the app, get the exact plan they need for their goals, show up to the gym and just put in the work, all for less than an hour of their time. You get access to over hundreds of programs and hundreds of different meal plans, everything which you could possibly need to get yourself in shape. So if you actually want to stick to something and see results without taking things to the absolute extremities Click the link in the bio. Let's get on with the video. What's up guys? And welcome back to First Things Thirst. We have the peptide expert Dean Henry in the building today. How are you doing?
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A
Very good, Mike, thank you for having me. Lovely view.
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B
Yes, yes, I'm looking forward to this. I mean obviously peptides have been all the rave recently, like the past couple years and particularly the past year. Everybody's talking about it, everybody's experimenting with it, but there's a lot of things which people need to be aware of and a lot of misinformation out there which you've said obviously is quite annoying for someone like you who's, who's been in the game for a very long time.
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A
Yeah, it's frustrating as I say, you know, I've been, been around this for 11 years now and the great thing now is there is awareness. So a good thing of awareness. Everyone's jumping onto it. But of course when something's popular, especially now with the rise of social media, there's some things definitely to watch out for. For sure. Yeah.
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B
How did you get into this space really?
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A
Just from my background. I was, I did some sport when I was younger, had some knee injuries, decent level as a spri footballer. Snapped my ACL when I was 15, 16 and really I just kept getting misdiagnosed like it was shaving my cartilage instead of work on the ACL. I mean I was 15 a long time ago. So it was, it wasn't quite there with the advancement of medicine we are now. And then it was just about regeneration. And I came across a podcast I think in 2015 and they're talking about epitalon, epithylon, which is anti aging at cellular level, showing that years of Russian data were showing that you could increase your telomere length after seven years. So literally reversing aging a cellular level. Just get me that. Yeah, So I jumped on that and then from there I've just been rabbit holing and deep diving for 11 years
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B
and experimenting with yourself.
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A
Lots of, lots of self experimentation. Yes.
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B
So, okay, let's, let's go to the very basics of what a peptide is. For those people who don't know what is a very kind of simple definition.
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A
Yeah. I always like to give two answers here. So there's, there's a peptide that we, we get in our food that you know, when you eat a steak, it goes from a protein to an amino acid to a peptide. So it's just your digestive enzymes break it down to a peptide processes in the body from your hormones to your immune system. So without peptides it wouldn't exist. They're just small chains of amino acids. Normally one, well, it's two chains of amino acids up to 50 depending on who you speak to above 50, a polypeptide above that, protein therapeutic peptides, which we're going to discuss today. So these are signaling molecules. So again, two chains of amino acids to around about 50 chains and then these target receptor proteins in the body mostly and they trigger an endogenous response. And generally these peptides are always found in the body. I always say this and I simplify it, that these peptides are found in the body, but that's not exactly true. So it is true, but it's a more specific. So peptides are made of these 20amino acids that are found in the body, essential and non essential. So with these 20amino acids, they're sequenced in different ways to or modified and sequenced in different ways to have a different objective or target area. So there's around about a trillion trillion different sequences you can have. When you think about, you know, you could, let's just say it's from number one to 20, you could have 1, 2 and 3, then you could have 3, 2, 1, you could have 120. So bases are trillion trillion, I've been told. So these different sequences are then created by people a lot more intelligent than me to target different areas in the body. So as an example, C Max and Celanq, that's a seven chain amino acid. Now C Max and Selenk is for neuroreceptor and cognitive health. Now C Max, which is for cognitive energy, comes from a stress hormone in the body. So it's a derivative of a stress hormone in the body. So this stress hormone is 4, the extract is 4amino acids. They then add another 3amino acids to it and then you can take it as a nasal spray and it's more stable and goes straight to the neuroceptors and breaks the blood brain barrier. So it's just one example of many. But so the amino acids are found in the body. The sequences are not always found in the body, but derivatives are.
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B
Okay, so in very basic terms, a peptide that you take externally would go into your body and start signaling to a particular area to, to fix, repair, to start doing something if it stopped
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A
doing something, to optimize and to regenerate. So I always, so I always sound like I'm dumbing this down, but it's for myself. I Have no. I'm not a medical person.
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B
You need to dumb this down for me.
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A
This is for me, so I can explain it. I often do use analogies. So when we, when we take these peptides, they're then looking for receptor proteins in the body. These, I say like doorbells. So it's ringing the doorbell and so what we do, we're not actually letting the peptide in as such. If we was taking say steroids or growth hormone, where a stranger's ring the doorbell, we're letting that stranger in, then it's endogenous, we don't know what's going to happen. Yeah, so it's exogenous going internally. When we take a peptide, it's like what we used to call knock down ginger in the uk. So it rings, it, it rings a doorbell runs away but creates activity in the house. So you're not actually letting a stranger into the house. And this is why when taken sensibly is a real to it because you're not actually really letting anything in in theory. So that, that's how most peptides work. Not all how most peptides work.
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B
Okay, and then the, the rise in your, in the popularity recently, where does that come about?
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A
That's because of the GLP1s, the Ozempic and the, the skinny pens, the, you know, the, the, the weight loss and that. So they are basically peptides. But I would always put them in a category of peptide drugs. The reason for that, they've been modified to stay in the body longer. So this, this analogy again, I'm going to use this quite a lot today probably, but this analogy of bringing the doorbell and running away suddenly because we've extended the half life now, turn this into a drug, they're keeping the finger on the doorbell for longer so you start to desensitize or the receptors. So now they need to start increasing the dose and it's staying in the body for five to seven days depending on the glp. And that's when we see side effects. So essentially when we take a GLP is hitting multiple receptors at the same time. The higher the dose, the more receptors gonna hit. And it's staying in the body for an average of six days. That's the downside of what I would call a peptide drug, the pro to a peptide is that they don't stay in the body very long. They bring the doorbell run away for sometimes for minutes. The downside to that is you have to take them multiple times a week or sometimes multiple times a day to
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B
get the optimal outcome okay, so that's the basics of what they are in terms of the sort of the stigma and the potential downsides and disadvantages for health. What might that be for a peptide?
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A
I think it's misinformation because I say we see a real safety profile with peptides. I've never really seen any side effects from my clients or people on advising, educating for 11 years. And we always stay safe, low, slow, stay safe in the parameters, take, you do the correct cycle, six weeks on, six weeks off for many. And I think what's happened now is that I'm trying to be diplomatic here is a lot of medical people have jumped on the back, of course, influencers, PTs, everyone. But it's, for me, it's more dangerous for the medical people that are jumping on the bandwagon because these are the people you should, you should be listening to in theory. And they will say, well, only use a medical professional for peptides. Well, by default that doesn't make sense because peptides in general, apart from the peptide drugs, are research only. There are a few that are FDA regulated now, but in, in the mass or not. So there is no human studies. So if they're saying use them for medical purposes, then that actually is probably more gray than what I'm doing because I'm not a medical professional. So we need to be really careful here. So then you get these people, these doctors all over social media trying to monetize from peptides. I say, well, these have got popular. Just use me, I'm medical professional. And then some of the protocols that I'm seeing from them, probably because I'm noticing more really, really worrying. Yeah, MOT C is a big one. So Motsi is trending a lot at the moment. That's exercise mimetic. So basically all the benefits you get from exercise about doing exercise, of course you should do the exercises. And the problem with this is that this does stimulate the receptor proteins. It does ring the doorbells, but it's going in a deeper level. It's DNA encoded. So because we have mitochondria, it's a mitochondrial derived peptide, because we have mitochondria in every cell in the body, it's literally hitting every cell in the body. So taking this like a normal peptide, which is generally five days on, two days off for six weeks, is actually quite dangerous because it trigger mast cell activation, as in a histamine response without you being allergic to the actual peptide that you're injecting because it's so potent. So I'm seeing these Protocols from these doctors and online and hearing it through clients that come to me that they're taking this peptide every single day for six weeks. Ridiculous. I was told eight years ago, I mean, moxie's quite new. It's 2015, I think it was founded, and people are taking that every day because they think they should take it like a normal peptide where in fact you just pulse it like three times a week for two weeks. Take a break.
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B
Yeah.
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A
And that way you avoid the histamine response. And I've seen some really bad outcomes actually from top doctors in the US given these protocols. And people are going into anaphylactic shock
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B
and this is just simply ignorance on their part, not understanding the effects or they're just wanting to monetize by selling more.
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A
Both, both. They said, you know, this is how peptides work. I've been on a two week course and that's what they do because they didn't learn about this at med school. And I feel like I'm really targeting doctors. I'm going to just do a caveat at the moment, but. So they just get this two weeks of information. They have no real life data on it because I haven't been working in it for the time that we have or people that I aspire to have. So, you know, I've got a couple of thousands of hours now of educating, feedback, anecdotal feedback. I see what a client's response is after four weeks. I know how to adjust the protocol. They don't have the information, they just don't. And it's so individual. I just want to say a caveat now is that the people I aspire to, the best people I work to in the industry are doctors. But they've been doing this for 15, 20 years. They've been doing in clinics, they're based in the us, they train at the Peptide University in the us and these are the people that I aspire to and have learned from. But they've been doing it for a long time.
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B
Yeah.
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A
So I just wanted to caveat that
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B
it's, it's something I've seen a lot now, even from just purely fitness influencers who have seen the potential for making money with peptides, suddenly announced that, oh yeah, I'm launching my new peptide companies. Like, what the fuck do you know about peptides? Like that's, it's ridiculous. But it's, that's just the way the world works. When there's money to be made, people will just jump onto it.
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A
Yeah.
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B
And I see it a lot with personal trainers and getting their clients in shape even out here. Like they will just recommend their clients to start taking these steroids just so they can get their client in shape and get the transformation. Because they get the transformation. They can put that on social media, they get more clients, but they have no consideration into the health damage that they're causing for their client and the, the permanent side effects that they're going to have after that. So it's. Yeah, it's a, it's a pretty sketchy area to be in it really. So how, if someone's like browsing through social media, what are the red flags and things that you should be aware of when people are talking about peptides and then who should you be listening to and taking advice from?
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A
There's a few variations that I think. Firstly, doctors have just started talking about peptides and, and you can see and they normally, the ones that say only use a medical professional, that's a red flag straight away because that's not really the case because these are generally research compounds. Number two is when it says not for human use, that's worrying. They say that to protect themselves. But there's a, you know, I had legal, as you can imagine, I had legal advice on this many years ago. And putting for research purposes only is fine. Putting for research purposes only, not for humans. When you are saying and selling this product for humans, it's just not, you know. Yeah, it's not ethical. So that's, that's number two. And number three is a little bit difficult to explain. But it's just over the years I can visualize and see when a peptide sold online if it's a cheap peptide or not and hasn't gone through all the testing and studies. And the other red. And a good thing to ask people that are buying peptides or you're buying peptides from is when they say their purity is high. So 99 purity or whatever. We see it all the time. I would always say to them first, can you tell me about the toxin endotoxins? And that was. And if they respond by saying the purity level is really high, they don't know what they're talking about because purity doesn't relate to toxic level.
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B
Okay.
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A
But they think it does.
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B
Okay. So, yeah, that's, that's one thing again I wanted to dive into is the sourcing of the peptide itself. The best peptides, is there a specific area where they're usually produced? Is there other areas in the world where they tend to have a lower quality, a higher toxicity Level compared to others.
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A
Yeah. So again, diplomatically from, from Asian countries, China. I've been doing this a long time. So diplomatically. Look, peptides from China is, is they have a bit of a stigma associated with them. Not that, not always so fair because you know there's a small percentage of, of labs in, in China that probably produce some of the best peptides in the world. But then we're talking about the raw material. So when you go from raw material to putting into vials, this is when you start having toxic exposure. And this is where you know, some of these sort of developing countries if you like, they sort of struggle. So at the very worst case to have the raw material from a good CGMP certified lab in China sent to somewhere in the US that have a lot of experience this at a CGMP certified lab in the US that are doing the filling. That's a good place to start. Ultimately at the moment where we tend to get our peptides from is it's all created in the US The CGMP C lab is in the US and they also connected to our lab in the EU where we're having the ready made peptide pens and that comes from a lab that's CGMP certified and they also deal with oncologists. So we know we're dealing at a good level here. So it does take a bit of research. But you know, going online, seeing these little 3ml vials, silver foil, you know, shiny foil labels selling BPC for 50, 60, you know, it's a real red flag for me.
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B
What's, what's on? Because you mentioned the, the foil label, what is actually the logo?
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A
Well so they, in generally they will get this from a source in far, you know, in Asia or the Far East. And I would say can you just give me BPC 157 10mg. They buy it for $5 and they say oh yeah, we'll customize this for you. A white label. So white label it there, stamp it, get sent to them in the UK or wherever. And then it is tricky.
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B
Like how would you, if you were a consumer and consumer and you get it like you, you just, you wouldn't really be able to know. It's not like you can do a home test.
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A
No.
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B
And this is something you're just going to put into your body.
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A
Absolutely.
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B
Like that freaks me out. I thought of that and I'm trying to go back to what you originally said. The original peptide could be fine, but it's the container that it's put into. That's the problem.
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A
Yes. In the labs generally they will have, they will receive the raw powder. So the raw peptide powder, the compound, that compound needs to go into a vial so they can sell it. So they might buy this powder for very, very cheap, for one kilo. That's a lot of 10 milligrams.
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B
Yeah.
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A
Right. So then they need.
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B
But it's good quality, though. It could be good.
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A
It could be good quality. Absolutely. But then it's that process, you know, what, what, what method are they using? You know, for example, the, the lab in EU that we're using, they have got, you know, got the, the shielding, the glass shielding. They put their hands through these gloves.
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B
Oh, yeah, yeah. So it was very sterile environment.
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A
Absolutely. And this is what you need to do. You know, no corners in the room, so there's no bacteria being caught in the corners. There's a, there's another level of, think of, of, of conversation and majority of the stuff on the market, I'm pretty sure, doesn't cover all those aspects.
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B
Damn. Okay, so people need to be very careful and cautious.
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A
Absolutely.
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B
Moving on to. I want to go through some of the most popular and trending peptides per sort of category. If we move on to the peptides trending in research and metabolic health. Retatrutride, Retro, Tri, Retrutride, Retatrue, Tide. Say it for me, please.
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A
Retatrutide.
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B
There we go.
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A
Yeah.
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B
So what's that one all about? Why is that the trending at the moment?
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A
So that's a triple agonist. It's going through medical research at the moment, should be launched for doctors and clinicians later this year. So that's evolution. So that's what they call triple agonist. So we had Ozempic, which was a single agonist. We had then Mounjaro, which was a dual agonist, and now we have Retatrutide, which is triple agonist.
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B
Okay, so what the hell does that mean, agonist?
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A
Agonist. It means it's triggering receptors in the body to perform born better.
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B
So you're saying it's like what, triple agonist is three times better?
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A
Essentially.
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B
Very simplified.
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A
Essentially, yeah, yeah. I mean, if I just break it down a little bit about being too boring. So Ozempic, which was the GLP one.
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B
Yeah.
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A
So that's appetite suppressing, slowing down, gastric emptying. And then you have Mounjaro, which is a GLP one, and a GIP which is a glucoline insulinotropic polypeptide. And that's basically enhancing what the first one did. We then have retatrutide. Now what seems to be happening with these new, these additional agonists, they seem to be mitigating this potential side effect, side effects from the previous agonist. So what happens with glucagon is it helps balance your glucose variability. So like when a diabetic takes their insulin and their glucose levels drops too low, they then need to take a sugar pill. Glucocon in theory is doing that. There's no sugar. It's balancing out that glucose variability. And that's why I took it because minimizing glucose variability is really good for anti aging longevity. So you take that, you get a more balanced glucose levels.
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B
So you weren't taking it because you were just being a little fatty like eat too much. You actually wanted for the, the other
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A
health reasons as well, for longevity. I, I've, I mean apart from a little thing I did last year, I've never wanted to lose weight. I've always struggled to put on weight. So I would never take a glp. It goes against everything that I want to do. Yeah, but because of longevity aspect, that's why I took Retitrutide. So that's the triple agonist. Glucagon has other benefits like helps you maintain muscle while you're losing fat. That was a big thing. When people were taking Ozempic and Mounjaro they were losing too much muscle. So it seems to balance that out and that's why people are, are really enjoying that particular product. And because this is a peptide drug, my guidance and education to people is to do a microdose. Because what we're trying to do is we're trying to take a peptide drug and turn it into a therapeutic peptide like the bpc. So the best way to do that from my experience is doing a super low dose two or three times a week.
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B
And what would that look like?
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A
Super individual. But generally it's half a milligram. Monday, Wednesday, Friday. Some people, someone I worked with the other day, I've got them doing 0.2. So that's 0.6 of a milligram per week. But 0.5 seems to yield the best results for the less side effects. Put this just to put this into context. From what I can see when it's launched medically, they're going to get people taking one shot, 9 milligrams to 12 milligrams per week. 10 times more than what we're working on and seeing good results from.
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B
Okay. And for what period of time? And there's. It needs to be a cycling aspect.
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A
Six weeks on.
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B
Yeah.
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A
And then the six weeks, then we say six weeks off and then decide whether you need to do it again. The whole idea of taking peptides is to get your body, your base level to a certain level and then it's about your lifestyle. The better your lifestyle is after you've got to your optimal outcome with the peptide, then by default the reason why your peptides are less functional is because you're aging. So the better you do with your lifestyle to maintain aging at a cellular level, then the less time you'll need to do peptides. If you finish a retitute, I'd say I've rebounded and now I'm eating crap, going out, drinking, you know, sleep's all over the place and you're going to need to go back on it sooner.
- [21:23]
B
Does that tend to happen?
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A
There are some people that it's habitual because they've stopped taking the retro truth. It doesn't work anymore. And they've told them so. I'll be bound.
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B
I'm really hungry. Yeah.
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A
I say, well, that's not. I don't think that's really the case.
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B
Yeah.
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A
And that's more psychological. And then it's about. All of this is about lifestyle. First, all the peptides. We're discussing the icing on the cake.
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B
I guess that's one of the biggest things that would be up for debate is the dosage and the cycling and duration of the cycling. Because I could ask probably loads of people, maybe even like a lot of people like you who really know their stuff, and I would probably. I don't think I would get the same answer back every single time.
- [22:03]
A
No, similar. I would say similar. As long as they really do know what they're talking about. And this sort of 4 weeks to 12 weeks, I know that's quite a difference, but that does depend on the individual. You know, the Peptide University I'm planning to do some work with, they. They run a lot of their cycles for 12 to 16 weeks, which is a long time. It's very hard for me to go against what I've learned because I've seen such great results with no side effects and it's low, slow effect, generally five days on, two days off, six weeks on, six weeks off. I've seen such good results. There's no reason why I would feel I'd need to change that.
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B
Yeah. Is this something you can easily get at this point?
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A
What sets. Yes.
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B
Yeah.
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A
Yes. Yeah. I mean this is all for research purposes, obviously.
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B
Yeah. So what does the future look like for this in particular? Like, is this going to literally solve obesity in America, for example?
- [22:53]
A
Absolutely. That's, that's the, I mean, it's 20. I mean even lipid panel, we've seen improvement with lipid panel, brain fog, hormone health and weight loss. Of course, my concern is the level that I'm hearing they're going to go to market at that, that worries me because then we will see side effects for sure. You know, I've seen what that, what
- [23:12]
B
they're going to be recommending.
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A
Yeah. So they're saying between 9 milligrams and 12 milligrams, one shot per week. And then we've been seeing that 0.5, three times a week. Works well with no side effects. Some people have had side effects. Myself, I stopped after two weeks because I noticed that we've been too graphic. I noticed my stool quality wasn't as good. So, you know, I said, well, this isn't good, you know, if my stool quality is not as good as what it was, something, it's going somewhere. So I stopped, took six weeks off and then did it again. And it seemed that my two weeks is just at my maximum level. So that was so individual. Yeah, but of course we're, my job really is educated and working with healthy people to make them healthier or, you know, longevity, anti aging prevention in medicine. That's not what they're doing. They're working with obese diabetics. So at 9 milligram, 12 milligram might, might be what's working for them. But you know, the researchers and the biohackers and the health optimizers, they need to take that into consideration. I've seen rebuttal on my, on my posts and, you know, YouTube videos I've done before. They said, oh, you shouldn't be doing microdosing. Retitrutide. Who told you this nonsense? You know, you've got to hit all your receptors at once, do high dose, one shot. Where'd you get all this rubbish from? Okay, well, firstly, it's based on my anecdotal evidence for the last year. I've seen some great results. And secondly, I'm always trying to avoid side effects and, and you know, it's basic science. The more receptors and the longer the half life you're hitting all at once, the higher chance you've got a side effect.
- [24:29]
B
Yeah, I guess we're only going to find out in like five years, 10 years, 20, you might even Be looking back and be like, oh, dear, that was a. That was a big mistake. Because it is. We are in the early stages. Like, there's. There isn't really any long term scientific studies done on this quite yet. It's the same thing with, like all this biohacking equipment.
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A
Yeah.
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B
It's trending and like, everyone's like, oh, I gotta do the red light therapy and the oxygen stuff, the saunas and the cold plunges. And it's just like, this is. Maybe it's not actually as good as we think it is. Maybe it's still that placebo thing in the head.
- [25:02]
A
Absolutely, yeah. I mean, generally, you know, most of us are intuitive enough to know if something feels good or not. You know, training, energy levels, sleep. Now, if all these things are optimized and you notice that from something you've been. Protocols you've been running, then generally that's a. That's a good sign, I'd say.
- [25:15]
B
Yeah.
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A
There's a. Let's see what the future may bring.
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B
Yeah. What about. Oh, God, I can't even pronounce these, Ty. I think I'm like a little bit dyslexic. We'll find that out today. Tazepeptide. Tirzepeptide. Tiraserpeptide.
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A
Tirzepatide. Tirzepatide, that's Mounjaro. So that's a double agonist that we just spoke about.
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B
Okay. That's another name, Semaglutide.
- [25:41]
A
Semaglutide is the ozempic. So that's the single agonist. So Semaglutide, which is Ozempic, was first, Tirzepatide is Mounjaro, was second. And now retatrutide, which doesn't have a medical name yet, but it's called retatrutide.
- [25:52]
B
How can it not have a medical name yet? But it has a name.
- [25:54]
A
So it's got a scientific name. So the scientific name for Ozempic was semaglutide.
- [25:58]
B
Okay.
- [25:58]
A
The scientific name for Mounjaro was Tirzepatide. And now the scientific name for retatrutide is retrotrutide because it hasn't been launched into the market yet.
- [26:07]
B
Okay, so that's gonna have a new name.
- [26:09]
A
I guess so. I guess so.
- [26:10]
B
Who the hell's naming all these, by the way?
- [26:11]
A
I guess it's big pharma. Yes.
- [26:13]
B
So they. Yeah, the big pharma. Whoever, like, creates it. It's like, I'm gonna call it this.
- [26:17]
A
Yeah, yeah. So Eli Lilly is the producer for Retrotrutide.
- [26:21]
B
If you created one, what would you call it?
- [26:25]
A
DH super fat burning peptide.
- [26:28]
B
Okay. Moving on to recovery, regeneration and performance. This would be obviously interesting for me because I want to maximize performance, maximize and optimize recovery. We have a couple of ones here. I guess the popular one, the BPC157. Yep. Body protection compound.
- [26:50]
A
Yeah.
- [26:51]
B
Why is that so good?
- [26:52]
A
That's probably one of the longer standing peptides that most people have been working with. When you mentioned why did I get into peptides? The regeneration aspect. BPC157 was the first one I took. So that's a 15 chain amino acid that's found in, in the stomach and gastric juices and that helps your gut repair. So taking it systemically will go around the body and look for parts of the body to repair. It works well with blood tissue cell migration. Sorry, blood vessels cell migration. Soft tissue like connective tissue helps rehabilitate this. I've seen some amazing results over the years. Just even today someone posted messaged me saying how quickly their knees recovered. And even just for you know, a lot of the hyrox athletes now they take BPC as part of their training because you are better from training, you just rehabilitate better. You're able to push harder in the gym especially if you're planning or training for an event. And yeah, that's a 15 chain amino acid that focus on connective tissue mainly but also really good research around heart health because of the blood vessel optimization.
- [27:46]
B
Okay, that's interesting. So I guess for those people who are training regularly and need to perform at their best, that is something that would be worth looking into. Because I imagine if somebody is just casually going to the gym taking seriously but they're going three times per week, would there be a need for them to take it? Because assuming that they're eating right and they're sleeping right and then having like a rest day or two rest days in between each session, very unlikely.
- [28:15]
A
But you know, if there's someone that gets quite a lot of niggles and you know people, you know doing shoulder press and their shoulders are getting nigga, they don't seem to recover then for me that was the last time I did bpc. I just got a little niggle in my shoulder. It was doing something really silly actually. I wasn't training, I won't talk about that but. And it had a niggle there and then you know, I took the BPC and I can just tell, you know, when I get this I thought oh, that will hang around A while to. The BPC cleared up in five days. I know previously it would have taken weeks.
- [28:38]
B
Yeah.
- [28:39]
A
And I was back training again. So there's always a, always a possibility to take it. But you're right, you know, just let the body recover, eat well, do your saunas or whatever and see how you feel. But if you're still not recovering.
- [28:49]
B
Yeah.
- [28:50]
A
And that happens when you get to my age. It can happen. Then you start, then you might need
- [28:53]
B
something like, guys, this is 78 by the way.
- [28:59]
A
I act like. Yeah. So, yeah. So for regeneration, it's, it's good for training, recovery. And as I said, if you're an athlete and you're competing, then I think
- [29:08]
B
for me, because I, I'm obviously at the point where I'm shifting quite a lot of weight and the form is controlled, I don't feel like I'm overdoing it at this stage. But I have noticed recently, whenever I've been pressing, particularly any kind of like incline press or shoulder press, there is a, I'm aware of something in my shoulder that's like limiting me from really giving a hundred percent. And I'm always a bit wary of that. Usually what I would do in that scenario is I would just not press for a while.
- [29:37]
A
Okay.
- [29:38]
B
Or maybe I would completely change the position of the pressing. So instead we do a neutral press and just leave out any pressing where I'm sticking the elbow up. But I feel like something like this could just heal it.
- [29:50]
A
Yeah. Especially if it's something you're aware of and it's been around for a little while and it's niggling then. Absolutely. I mean, you know, I've seen, the thing is, I've seen, I shouldn't call them kids, but 25 year olds taking BPC and they've got tendonitis in their elbow and they heal in three days. Because their receptors are so sensitive, they still optimize as a, at a cellular level, the peptides still optimum in their body because they're so young. Whereas someone a bit older or you know, closer to my age and they take it for tendonitis. You can see it can say two to three months.
- [30:20]
B
Okay, that's interesting. So the older you get, the, the slower the response might be more often than not.
- [30:25]
A
Yes.
- [30:25]
B
Yeah, yeah. And is, is there a point where, you know, you could be too young and should be completely avoiding it or is that not an issue?
- [30:33]
A
I think really just, just by default, I, I, I, anyone under the age of 21 just seems pointless. You know, you should Be at your optimal recovery anyway, you know, even up to 25. That's when start, that's when a lot of these sort of peptide functions and growth hormone everything starts to decline. But any, anything below 21 would seem a bit ridiculous.
- [30:50]
B
You're pretty much invincible that age. Yeah, I would go straight into the gym and crack on with my working heaviest weight without any warm up and I'll be absolutely fine. Then you realize after doing that like you get into your late 20s, like you definitely can't do that. No, no, you'll have a wake up call.
- [31:06]
A
I think I spent half an hour warming up, 10 minutes training.
- [31:10]
B
We'll get back to the podcast in a second. But first of all, I want to say a massive shout out to Bionic. I have been using their supplements for the past four years. I never knew what supplements I needed to take. I'd always go into the pharmacy and buy a load of random bottles and end up popping pills all day, every day, not having a clue if I was consuming the vitamins which I should be consuming at all. But Bionic came to save the day. They are a tailor made supplement company that will put together your own specific formula based on your activity, your gender. I have Bionic Pro where I get the blood test done every three to four months and based on that blood test I get my own personalized formula for those people who don't want to do a blood test or don't have access to that. Then you can go with Bionic. Go where you just have to fill in a short questionnaire. And based on that questionnaire you will get your tailored supplements with a surprisingly high degree of accuracy. So stop the guesswork, sign up to Bionic and ensure that you remove those deficiencies and build up your immune system. Okay. TB500.
- [32:17]
A
Yeah. TB500. So that, that works very well. It's synergistic with BPC157 frequently put into a blend. So it's from the thymus. It's generally a fragment of Thymus and beta 4. So Thymus and beta 4 is in basically all the cells in the body. This helps regeneration. That's a 43 chain amino acid thymus and beta 4. TB500 is a synthetic version of that does very similar to bpc but it focuses on soft tissue tissue. So where BPC was connective tissue, this is soft tissue. So muscle fascia, so it does that. So working the two together is amazing for rehabilitation. TB 500 is often referred to as a fragment 1723. So that's a 17 chain amino acid, which is extracted from that 44 chain amino acid. Seven of those and then it's got another 10amino acids to make it more stable and more effective in the body. But it's just sometimes people called TB500, TB500, when it should be called 1723. The only difference is it's more targeted. Whereas TB500 and it's 44, 43 chain amino acid for it is more systemic. It goes around the body more broad spectrum. When you take it in the 1723, the 17 chain, that's more specific to the target area.
- [33:31]
B
Okay.
- [33:32]
A
Important for both. They can be used intramuscular or with a clinician or medical professional. So I've had my elbow using both of those under ultrasound. So very long needle. And then they've put it into the area and that's not fun. Yeah, but then. But when it's intramuscular, then it's less systemic, so it's going to stay in the target area. I get that question all the time. People say I've got my insulin needle where, you know, and I've got a bad shoulder, so I inject it in my shoulder. For me, it's ludicrous. I mean, it's subcutaneous. So unless you've got a long needle, you're actually going into the area. Which I certainly wouldn't suggest doing at home. Yeah. Subcutaneous would always be the safest option.
- [34:10]
B
So you mentioned a blend. Is that something where you're getting the two individuals and you're putting them together?
- [34:21]
A
The labs will generally make a blending for you. Yeah. So it'd be. It'd be just. It'd be in one vial or in one pen. And they'll put the blends together. They're normally synergistic.
- [34:29]
B
There's a specific ratio which is.
- [34:31]
A
Yes. Yeah. And that can work for you and against you. There's a lot of. Again, there's some doctors online that are making me smile at the moment talking about disassociation. When you put one peptide with another in, the ph level will start to interact with each other. It's absolutely. It's mainly nonsense. But to optimize sometimes BPC and tb, for instance, bpc, Ultimately, if you're trying to recover from an injury, you should take twice a day, five days on, two days off. TB500, you should probably either take every day or Monday, Wednesday, Friday, as an example, a slightly higher dose, but only in the mornings because TB500 can disrupt sleep. So if you take them together, you're Already losing. If you, if you, I mean, if you're not, if you don't care about disrupting sleep, it's fine. But if you want to have maximum sleep, which is the key for a foundation for recovery, then you don't want to take TB 500 in the evening, which means you can't take it with a bpc. So I get it, but it's not always optimal.
- [35:23]
B
Interesting. Okay. CGC1295+Hypermorelin. The same.
- [35:34]
A
Yes.
- [35:35]
B
Get it. This is the first time I'm saying half of these. You know, this is the, the growth hormone releasing peptide.
- [35:41]
A
Yeah. Growth hormone secretogs.
- [35:42]
B
Yeah. Okay, so that's good.
- [35:46]
A
Yeah. So growth hormone secrets are really good. So we talk about the doorbell again. So the doorbell in this instance is
- [35:51]
B
saying, create more growth hormone, more of
- [35:54]
A
your own growth hormone. So it's stimulating the pituitary gland, it's ultimately stimulating the pituitary gland to increase your own endogenous growth hormone. Really good. That's the one I was psyching whenever I'm, you know, trying to do body comp. That's what I cycle the most. Everybody loves these. You know, you're getting the, the, the benefits of growth hormone potentially without the side effects of injecting synthetic growth hormone into the body.
- [36:16]
B
Yeah.
- [36:18]
A
And yeah, you, you, you put on muscle easier, you sleep better, you've got more energy, you lose fat better. So it's just optimizing again when you're 25, your growth hormones, when it reached its peak, or probably a bit before that, but it starts to decline from age 25. And we know, as we just said, you know, you can train harder.
- [36:31]
B
Yeah.
- [36:32]
A
Sleep better, have less sleep, have loads of energy. So that's what optimized growth hormone does.
- [36:36]
B
Does. And it's something women could take as well.
- [36:38]
A
Absolutely. Yeah.
- [36:39]
B
Yeah.
- [36:40]
A
I mean, explain the differences. There are slight differences. So. Tessamerella, NASA 44 chain GHRH, growth hormone releasing hormone. Your growth hormone releasing hormone that's produced by the protruding gain is actually 44 chains. So Tesrella matches that almost identically with a slight modification to extend half life. That's a GHRH. CJC 1295 is also a GHRH, but that's a 29 chain amino acids. That's an extract from the 44 chain that generally if, based on my experience, other people may, may, may differ. Based on my experience, the, the tesserin is a safer place to start than CJC1295 because the latter seems to. And can stimulate a histamine reaction. So I would generally start with Tessarin, which is FDA approved for burning fish or fat actually. And then ipamrenan is a growth hormone releasing peptide. A GHRP does the same thing. Eventually it targets the pituitary gland, but it goes through the ghrelin hormone first. And the graying hormone is responsible for hunger. Hunger. A lot of people get worried, say I'm going to be more. It doesn't. It disassociates itself from the hunger stimulation and just goes from there to the pituitary gland. And then what you've got. People take these together, Testament, the GHRH and ipamorelin, ghrp. And that gives you the full spectrum, or close to the full spectrum of taking a growth hormone, an actual growth hormone synthetic drug. So this is. So taking the two together will give you potential.
- [37:56]
B
That's pretty amazing. So then would that kind of cancel out the need for you actually having full on growth hormone hormone?
- [38:03]
A
In many cases this would be where you'd start. And this is why Tess been approved and even semirelin I think was approved as a, you know, for the same effects as growth hormones. This is the safer way to do it. About putting exogenous growth hormone into the body. And then you, you got all these, you know, potential side effects. And most. You should do these first. You know, my, in my, in my opinion, it becomes an age when, because remember, we're just creating what's already in there to optimize. So there will be an age when maybe when I really am 78. Thank you for that. Where my, my, where my growth hormone's not really anything to grab onto.
- [38:34]
B
Yeah.
- [38:34]
A
So at that point there's no point me taking a secret that's going to stimulate growth hormones. There's nothing there. So then we'd start to take GH maybe.
- [38:41]
B
Yeah. So, okay, that makes sense. But if you, if you're trying these and taking these, you really have to be keeping an eye out for how your body's responding and whether or not it's actually working. So let's say for example, I'm, I'm the typical guy who's going to the gym. I want to get stronger, I want to improve my body composition, lower body fat, increase muscle mass. You know, I don't want to be jacked beyond belief, but I just want to, I want to have more energy, feel better, look better. What out of those ones we've just discussed would be an appropriate thing to do moving forward?
- [39:15]
A
Very popular protocol is TESS and IPAMILIN or CJC and ipamorelin for all the things we just discussed for optimized growth hormone and BPC and TB500 and you can get blends for both. So you can, you can do a blend of the, the GHRH and ghrp, the Tesla and you can do a blend of the BBC and TB500. So with that you've got recovery building muscle is. Yeah. Burning fat. So you've got a combination of two.
- [39:39]
B
You take all of them. All of them.
- [39:41]
A
And the thing is because, because you can do a blend because if you either inject yourself four times or two times. So if you do the blend, you only need to inject yourself.
- [39:47]
B
But you couldn't put it into one blend, all four of them.
- [39:55]
A
I would suggest not. I mean if you, if so what some people do. And again a doctor did this in the UK and there is an issue with this. But if you pull them all into one syringe, bit fiddly, you see, if it's not in the pen and you just pulled from four vials and put into one syringe and took it immediately, then that's the way of going around not having to inject four, do four injections at once. I did hear of one doctor that did this with all these different crossovers of peptides. Different families, different groups put them into a syringe for their client. It's quite a high end client. And said, right, take these away with you. And all these peptides are all.
- [40:24]
B
And they all died.
- [40:26]
A
I mean they're just gonna be so less effective and you know, they start, they will. The blends once reconstituted, don't disassociate. But all these, you know, mixing a bioregulator with thymus now for one. And you know, there's a reason why these labs again, a lot more, a lot more intelligent myself are doing certain blends are not.
- [40:42]
B
Yeah.
- [40:42]
A
So for these doctors I just put all in one syringe and keep in your fridge for six weeks.
- [40:45]
B
Yeah, yeah. Okay. Yeah. Just genuinely curious. And then for. There's a big topic at the moment of men having less testosterone than, you know, 20, 30 years ago. Whatever. Will these have an effect on overall testosterone production? Is there anything you can take to help guys improve their testosterone or is something they should do just literally by, you know, improving their sleep, reducing stress, all these other things.
- [41:14]
A
Yeah. Let's get the basics right first. We have to keep caveating this before we talk about peptides. So making sure you're going to bed around the same time every night, getting your minimum hours of sleep, eating food, lifting weights. Do this for, for a long period of time. And then if you're, if your testosterone is still not optimizing, you're taking all the different supplements and it's still not increasing, then we can look at some peptides, precursors really to producing testosterone. Because we're not, again, we're not putting synthetic hormones into the body. So there's one called Kisspeptin, which stimulates LH and FSH hormones. So that's like your precursor to your, your testosterone production. So again is all we're doing is ringing the doorbell to try and tell the body to produce more testosterone. We're not putting testosterone into the body, so that's really good. Also the test is bioregulated, as we haven't discussed the BIR regulators yet, but there are subcategory of peptides, 2 to 4Amino acid chains that you can take orally. And these come from animal, so this would come from the ball of an animal. So pretty much similar to your organ meats but a lot more defined. So and these, what's in it? They're basically 42 to 4 chain amino acids from the ball of balls, right from the testes of balls. And, and they naturally find the target area so they match up sort of the amino acid sequence. So they would in theory target the epigenetic environment of your testes, of your testicular function and optimize that, regulate it. So if it's down, if it's already down, regulated or upregulated, if in very unlikely event you was producing too much, it would downregulate it. So it's creating regulation for the target area, acting always. It's like a DNA switch. It's not changing your DNA, it's a dimmer switch. It's either going to increase or decrease. So really for thyroid, if you had hypothyroidism, it down regulates it. If you had hypothyroid, it would upregulate it. And there's 21 those.
- [42:52]
B
Yeah, yeah. It's fascinating because there's so many guys in the industry who are just so quick to hop onto TRT just because they want results quickly and they're, they're, they're either impatient or they've not looked at other areas of their life which can drastically improve. It's funny, I wonder, like, you know, you could be on all these different protocols of peptides and I guess you can kind of still class yourself as being natural. Like it'd be funny in the future to try and figure out at what point are you not natural? This is like a weird obsession people have in the fitness industry. Massive discussion people have about me and like other people, is he natural? Is he not natural? And then like in the future, you could be on this peptide protocol and doing all these different things, but technically not taking any steroids.
- [43:39]
A
No.
- [43:40]
B
So it's like, oh, we were. Technically, I'm still natural. Yeah, I'm not taking any steroids. But really, are you natural anymore without like everything you're taking?
- [43:49]
A
Here's some, here's some stories. So, but based on this conversation. So firstly, WADA or water, they banned a few peptides. Now, even though they're not deemed as pds, they have banned them. There was an American football team, I believe I was told this by one of my American counterparts that took BPC157 during training. So going back to the start, when you take these peptides are in out the body very quickly, you can't find them. You can't test for peptide levels in the body. In theory, you know, started saying, can I test your collagen levels? It's just not, not really possible. I mean, anything's possible, but you'd have to, you know, so it's. All we're doing is stimulating what's already there. Who can say that my production of testosterone isn't this high? Because all you're seeing is endogenous testosterone. There's no synthetic testosterone going into the body when I take his Peptin. But so the BPC157, they're all using it for their training. And then they went out and I think they won, you know, the bowl or something. And they were just so advanced, more than everyone, everyone else. And I said, what? What are you doing? And they said, we're taking this peptide, BPC157, it's fine, it's natural. And they said, and they looked into it and said, actually, you can't use this because you're able to train better. So because you can train better, that's not fair in everybody else.
- [44:55]
B
Yeah, because that is going to be a big thing now in the Olympics, all these other big sports categories. I mean, what's your opinion? Like you think, like, surely it's okay.
- [45:05]
A
Everyone's take it.
- [45:06]
B
Yeah.
- [45:06]
A
On a level playing field, it's fine. You know, and it's. And again, these things don't work unless you're enhancing your lifestyle. Anyway, anyway, so it's about your. I mean, if you're just Taking BPC and sitting around doing nothing. It's not going to do anything really. It might heal your gut, but not much more than that. Yeah, and it's for me, I, I shouldn't simplify it so much, but let's call it an advanced supplement.
- [45:28]
B
One which I'm becoming increasingly interested in moving on to cognitive and nervous system peptides. So this is I guess the peptides which is going to improve brain function, alertness, focus, all these things start off with Semax. What's this one?
- [45:47]
A
So Cemex. So Russian derived peptide. Founded in the 1970s or 1960s, it was used during the Cold war I believe for more focus for Russian soldiers. Loads of human data on it. And this helps stimulate neuroreceptors to be more cognitive. For cognitive energy and focus. I think I mentioned at the beginning it comes from the stress hormone in the body. So it's a four amino acid extract. Added another three amino acids to make it a seven amino acid chain. And the reason why they do that is so it breaks through the blood brain barrier and is more stable. And that really works well as nasal spray actually. So because you're, it's just common sense, you know, rather than take it subcutaneous right into the cream, straight to the neuroceptors and actually the great, the great. Even though you're taking it as a protocol for long term compounded benefits, when you do take as a nasal spray, you do feel a little boost straight away. It's important to understand where it's not a stimulant. We're just optimizing the neuroceptors to perform better. We're not stimulating.
- [46:45]
B
Okay, so it's not taking a caffeine shot, a whole lot of coke.
- [46:48]
A
No, no.
- [46:50]
B
Okay. What so, so if you took that, could that potentially fix a. An individual who just has poor focus and just has a poor attention span?
- [47:02]
A
Yes, absolutely. Yeah. Very common actually for females at perimenopause. They suffer from brain fog. Y often guide them to use C max as part of their protocol to help them with just uplifting mood. Well, more, more cognitive energy and focus and to help with brain fog. And over time we are seeing some good responses from it.
- [47:18]
B
Yeah. Okay. And then celan and am I saying that right?
- [47:22]
A
Silank is good? Yeah.
- [47:23]
B
Yes. PE2228.
- [47:26]
A
Yeah. So the solank is so I always remember slang by cilantro as in anxiety.
- [47:32]
B
Okay.
- [47:33]
A
And same thing, except for interestingly that come. That's the same as the C max is a seven Chain amino acid, but that comes an immune protein and that's been adapted to be a 7 chain again to do the same thing, be more stable and go straight to neuroreceptors. And that's really good for mood regulation, depression. So a lot of people are using that rather than antidepressants. Again, I couldn't advise on to people to come off antidepressants, but yeah, I've
- [47:58]
B
not heard good things about antidepressants. But we won't go into that obviously.
- [48:04]
A
Let's not do that today.
- [48:05]
B
Okay. And then the one which I am actually trying. Guys, guys, we are like five days deep into this one. Dihexa. I'm curious about this one. I mean for me and just my general approach to it so far I, I'm really quite happy with how my obviously my physique is, my performance in the gym. I don't feel like I'm taking a long time when it comes to recovery because my programming is so dialed. My sleep is on point and everything. But with my job on a day to day basis, I just need to be so switched on all the time. Time, like creatively doing these podcasts, being on video, like I just need to be always on point. So I'm speaking to you, speaking to Vadim about potential peptides for just improving brain function. And this, this is a good one apparently. I mean it said when you're taking things like this, you're not going to immediately start to see a difference. It would take, let's say for example, if I was taking this once per day, how long until things really start
- [49:02]
A
to research is around about four weeks. Yeah, but whether it, whether it's placebo or not, so many people start this and within a week they said they feel amazing. And really Dihexa, this is for learning and memory. And the research dictates that the more damage your brain is, the more effective it will be. But you know, brain damage in the terms that we're using is aging. You know, as I said to you earlier, my daughter's learned Spanish and six months I'm still struggling. Six years later I just say hello and goodbye. You know, and that's because my learning optimal. I don't learn as optimal as I do. So taking something di exa should get us back to that, that base level. Yeah. And again, yeah, that's just a nine chain amino acid. It comes from the, it's a, it's a derivative of the hormone that regulates blood pressure and they just add it again. They modified it and turned into A nine chain. And again this makes it more stable and for cognitive performance.
- [49:56]
B
Yeah, because for someone like me, for example, you're sitting down, you're doing a podcast with someone and they're just, just they're coming at you with so much information. I want to remember everything and it's so hard. So I'm hoping this can help to improve that.
- [50:09]
A
Yeah, I, I, this, this is probably really bad analogy or anecdote but we, I, I started taking Daxa so I, I watched these Netflix, you know, sit down with my wife, watch Netflix series or whatever and all these people when they watch it, they're talking about the actors, the actresses, the name of the program. I said I just don't remember that stuff. Yeah. You know anything about peptides? I remember it forever but stuff like this I just don't. In di exa we went out for lunch with some friends. I remember the name of the series actors and I just surprised myself. I said I really don't normally remember. So it's really good for remembering non important things.
- [50:43]
B
Is there anything you could potentially take for sleep quality and maybe even just like switching off and falling asleep quickly?
- [50:51]
A
Yeah. So two, two, two peptides to look at. Firstly the peptide bioregulator epital on the first one I ever took because it's enhancing anti aging. We know that the foundation of health is sleep. So what this does, it helps BAL or circadian rhythm. You can take it as a injection subcutaneous or you can take it as a capsule by a regulator because it's only two to four amino acid chains. So it does the bioregulation, the DNA switch that I mentioned earlier and that is really good for long term sleep, deep sleep. In fact the first 10 days you take it, everyone who takes it for the first time they need to take afternoon naps.
- [51:25]
B
Oh yeah.
- [51:26]
A
Which is good where I'm in Spain because we just haven't called it siesta. Right? Yeah. Everyone else is sort of, you know and it was just wiping me out. I just had to sleep, felt great, but got to sort of 1 o' clock in the afternoon, took a 20 minute nap and I felt good. Went to bed at 9 o'. Clock, deep sleep, amazing for that. And again that's the, just the, that's almost like the precursor to what it's for. It's for longevity and increasing telomeres.
- [51:47]
B
Well that's weird though because he's taking something to improve your sleep but then it's going to make you more sleepy in the day. So it's Kind of like. Yeah, there's a trade off there a little bit.
- [51:55]
A
There is 10 days, generally seven to 10 days. And then after that the next time you do it, it's not quite as
- [51:59]
B
profound, I think from my. Obviously I wear. Whoop. You've got aura ring, don't you?
- [52:04]
A
Yeah.
- [52:04]
B
So like there's ways to track it. Debatable as to how reliable and truthful it is, but I mean, we can say it's, it's quite good. But one thing I've noticed is I don't think I get as much deep sleep as I should. It seems to kind of max out at like one hour or an hour and something. And I don't know if that's got something to do with. Maybe I should try to go to bed even earlier than I am because at the moment it's. I'm probably falling asleep between 12 and 1.
- [52:32]
A
Okay. Quite late.
- [52:33]
B
Yeah. But then I wake up at like 9. So it's, it's not like the duration of sleep is bad. But more people I've spoken to have said you're going to get more deep sleep if you go to bed earlier. And then obviously you have to ensure that you eat a reasonable time before that.
- [52:51]
A
Yeah.
- [52:52]
B
Everybody's saying now that most of your calories should be consumed in the morning, early afternoon and then you kind of have a. I know this is probably going to be problematic in Spain because everybody likes to eat at like 10 o', clock, 11 o'. Clock.
- [53:03]
A
Yeah, definitely not us. We're the most boring family in Spain.
- [53:06]
B
Yeah. So yeah, there's like, there's a couple of experiments that I would like to make, but the sleep one.
- [53:11]
A
Yeah, well, there's so, so I've been taking dsip, which is delta sleep inducing peptide or deep sleep inducing peptide, which could be interesting for yourself. And that's a nasal spray. Again, it's targeting neuroreceptors and I take that when I'm traveling and I've been taking that this week. And yeah, generally when I get to hotels, particularly in Dubai and all the connecting flights, I sleep terrible. And I've been taking a couple of sprays before bed. And my deep. My sleep, my. Actually my sleep score's gone up since I've been here. I've been here four nights and my sleep score's gone up on my aura rather than when I'm at home. So that never happens. So yeah, dsip, really good. And you don't wake up drowsy, you feel good. I mean, maybe a little bit drowsier because you've had such a deep sleep.
- [53:49]
B
Yeah.
- [53:50]
A
But not like you've taken a sleep.
- [53:51]
B
Okay. So let's say, for example, I was, I was needing to travel and I'm going to be traveling for a week and then I've got the. There's the time zone difference. There's like new bed, new environment, maybe a little bit of added extra stress for whatever reason. Something like this you could do for that week or maybe the two weeks to get used to the time zones. And that should fix quite a lot of it.
- [54:14]
A
Absolutely, yeah. My only for this is fine. And the reason why I'm taking now when I'm traveling, so I don't take it when I'm at home.
- [54:20]
B
Yeah.
- [54:20]
A
Some people that really struggle with sleep, then I have research protocols for them which would be three times a week, Monday, Wednesday, Friday, if you're going to take it as a protocol. Because then my concern would be dependency. Even then, though it's acting as a peptide, you have this habitual type dependency. If I'm not putting something up my nose, I can't sleep properly, you know, so that's what we need to try and stay away from. And that's with a few peptides, oxytocin and things like that, where you get such a good dopamine response. You think, if I don't take the peptide, I'm not going to feel good. And this is when we need to be really sensitive.
- [54:49]
B
Yeah, I can see this being a big issue when people are taking things that they're noticing the positive side effects. Then there's the placebo on top of that. And the habit of doing, doing it to, to come off might make you think like, oh, no, like I need, I need to get back on it. It's like some guys who are taking steroids, like they get their body into this elite condition which they cannot achieve naturally. And they know that the only way to look at this is by taking the steroids. And they come off the steroids because you need to go off the steroids because you're going to destroy yourself. And then their physique is not. It's not as easy to maintain. They don't look as good. The body composition is not the same. And. And they're like, oh, I need to get back on it again.
- [55:30]
A
Yeah. And is it, I mean, maybe different for that, but there is placebo because you know what we're doing, as I mentioned with peptides, we're just increasing your baseline again. So when you stop, it doesn't just Stop working. That's not how peptides work. It's not a drug. And I have a girl in Ibiza at the moment who struggles from really bad anxiety. Even when she gets in a car, she can't drive, she's so anxious. So I got, I advised her to look at Sri Lankan, a peptide bi regulator called central nervous system. So she run these two together to regulate a central nervous system and take cellang before she gets in the car. And she just sent me a voicemail, she's almost in tears, where she said, I can't believe how good I feel. I'm not taking any of the stuff I was taking before for anxiety. I feel amazing now.
- [56:07]
B
She's speeding.
- [56:09]
A
I was gonna send me fines for speeding tickets, but then she said, I've come off them now and I'm really worried. And I said, well, you know, you didn't. She goes, I feel so good, I don't want to come off them. I said, okay, well this is when you need to understand the science behind it. It's not. Take a drug, it stops working. We're building up your base level. Yes, that base level might start to decline, but this is when you need to be intuitive. You know, peptides, you know, I think you need to have a certain IQ level to take them and be very intuitive and very aware because it's all about. It's a natural outcome, it's innate. And you need to just be very mindful, not just ignorantly take peptides. I think that's really, really important.
- [56:44]
B
I guess one of the hardest things is to, to measure its effectiveness because you could say to yourself, right, I'm gonna start taking these peptides, but at the same time I'm also going to focus on my diet and start eating cleaner. I'm also gonna start exercising more and also I'm gonna try and focus on my sleep. So you're doing all these positive things. How do you then know that these results have come from the peptide or from these other things that you might be doing?
- [57:15]
A
It's, as you say, it's almost impossible to test. Uh, interestingly, not for someone like yourself, but interestingly, people are more motivated when they take the peptides. See that a lot. So say right now, I'm taking the peptides, I'm going to stop drinking, I'm going to train harder. And they say, I feel amazing. I say, well, that was probably because you're training harder and stop drinking. And the peptides just maybe just gave you a little bit of enhanced effects, that's all Peptides are doing enhancing what you're trying to do naturally. So it's probably a combination of the two, but probably 80 lifestyle 20 the peptide.
- [57:42]
B
Yeah.
- [57:42]
A
And you can't test that, but you know, when people stop taking the peptide and they continue with their lifestyle, it's great. And then after a while they see a little decline, but it's no more than optimizing what you're doing naturally.
- [57:52]
B
Yeah. So let's move on to cosmetic and skin care peptides. So peptides are going to be making us look youthful and beautiful and all of that. So one which is quite common is the, the copper peptide. G, H, K, C, U. Yeah. Why is this so popular?
- [58:13]
A
Well, I think it's because it has multiple applications. It's a, it's a tripeptide, a small chain amino acid. So you can take a. It orally for gut health. Because it's so small, it just goes in and fixes the gut to go back. It's stimulated. It's the collagen doorbell.
- [58:28]
B
Okay.
- [58:28]
A
So it's ringing the doorbell to stimulate collagen endogenously. So you're basically creating better collagen production internally to externally rather than externally to internally.
- [58:37]
B
Yeah, I was going to say, like, obviously there's lots of collagen powders. Is one superior to the other or it's just. They're just different.
- [58:46]
A
Um, I think because you're talking about subcutaneous now, because you're taking it subcutaneously, you're hitting the, all these receptors more directly. So it's going to encourage more collagen stimulation than taking an oral peptide or, or a collagen. Because really collagen's been. There are some theories that it does the same thing with stimulating receptors, but in reality, most of it's been broken down in your gut. And fixing your gut, which has amazing benefits for skin because you're fixing your gut health, but you're not, you're not hitting the same receptors. The other thing with ghkcu, you can take it topically, you can do microneedling, you can do it in a serum, and you do it orally and you can take as an injection.
- [59:21]
B
So topically, what you talking about? Oh, okay, yeah, sorry. I've had a hair transplant. So any topically? I just assume.
- [59:28]
A
Okay, yeah, yeah. So on your skin topical application, and there are some serums where people are rubbing it into their scalp as well.
- [59:34]
B
Okay. And that would be okay to take. Let's say, for example, you did a blood test, you find out your copper levels are actually above. Above optimal or high, it's not gonna be a problem.
- [59:43]
A
Not a problem. But for those people, I would take zinc with it, just to balance it out.
- [59:46]
B
Okay. Okay. And then. Matrixyl and acetyl. Hep. Hexapeptide. Ape, common in skincare for wrinkle reduction and surface.
- [60:03]
A
I wasn't aware of those. It's doing it.
- [60:05]
B
I probably weren't aware of it because of the way I said it, to be honest.
- [60:08]
A
No, no. Well, that was the start. I was thinking, oh, I don't know about these peptides. Um, but I have seen them. A lot of people ask me questions, and I'll be. To be brutally honest, I don't have much information on them. They're. They're being discussed a lot in the cosmetic industry. And, you know, all the peptides we're talking about. I've got a lot of research and data and time. I don't know those two, so.
- [60:26]
B
Okay.
- [60:27]
A
I would. I wouldn't comment on something I don't have much knowledge on.
- [60:30]
B
Good answer. For most people, they want their skin to be better and they want to reduce the risk. Wrinkles. Would there be. I mean, apart from those are the ones that are, you know, maybe you don't know so much about. Is there any other ones which are gonna be good just for looking better?
- [60:45]
A
Well, the GHKC copper, for sure.
- [60:47]
B
Yeah. That's the main one.
- [60:48]
A
That's the main one. And that's stimulating. Everybody loves that because it's stimulating collagen production. And also this is really good. Some people add that to their injury repair. Because your tendons are 90 collagen. So you're taking BP. This is a stat, by the way. BPC, TB500 and GHKCU together, you're healing your tendons. So people love that. With the side effect having better skin and collagen production. Yeah, so that. That work works really well. And the collagen microneedling, the GHKC microneedling, There's someone in Dubai that does it. My daughter does it in the uk. She's an aesthetics nurse, and she uses the GHKCU to stimulate collagen in the face directly. So within two weeks, you see really good results. Actually taking the two together, subcutaneous and in the face, micro needle, and you're going to see some great results. And then hair loss, my expertise, obviously, I'm out. The amount of people that ask about hair loss, it's a strange one, but no, I missed the boat there. Obviously. Ghk, so AC Copper again. It stimulates the hair follicles so good for hair thickness. And then rubbing a serum.
- [61:42]
B
I'd be so annoyed if I took that. I right, let's get some like thicker hair. And then I just end up having like the hairiest test ever. I'm like oh nice, cool. Like just back hair.
- [61:52]
A
Imagine, imagine. Yeah, that work. It tends to work well and as I say some people getting the exosomes and the GHKCU micro needing this, the scalp that, that tends to work quite well. So there's a lot of advancement in, in hair regeneration at the moment I'm not there. Some people say they've got found some results in actual hair loss in baldness. So some people saying the nail got some products on that. But yeah, I'd have to leave someone else to discover that because I look really silly with hair. So you know me walking around with an afro.
- [62:23]
B
I can tell you that a few of the ones, I mean, I guess one thing that I wanted to discuss versus gut health because I think that's very underrated and is a cause for many issues that a lot of people will be experiencing. So I think maybe some of them can have a positive effect for the, for the gut health. Is that, is there a peptide in particular that is sole focus is to improve gut health or does that, does it all work like that?
- [62:48]
A
Yes, it does, absolutely. There's a combination that I like because it's one that we haven't discussed yet today. Lorraine. So lorazatide is an 8 chain amino acid that's actually not found in the body, it's found in a bacteria and water. So this is one. When I said most peptides target receptor proteins, some that don't, this is one that doesn't. This one actually targets tight junction proteins and they're like the little guardians that are responsible for intestinal permeability and protecting your cells. So when people have got leaky gut or intestinal permeability, they take something like lorazatide orally. It closes up the permeabilities in the gut. So this is. And it's been studied heavily for celiac disease. Yeah, just to heal your gut. It's going to be very difficult to heal your gut if you've still got leaky gut. So starting with lorazatide is really good. GHKCU is good again helping the collagen. BPC which is found in the intestinal, in the intestines is juices is really good. TB500 is good. So all this sort of systemic Healing we're getting for subcutaneous injection because these amino acid chains, they don't break the endothelium when you take them orally, so they don't go into the bloodstream as such. But they are healing your gut. You don't need it to go any further. And the only one that would add to that which is also good for skin actually is kpv. That's a tripeptide. That's at the end of the alpha melanocyte stimulating hormone which is responsible for melanotam 1 PT141 for sexual is melanoton peptide. Yes. So this is when the bodybuilder bros start coming out. So I've been taking peptides for 30 years.
- [64:13]
B
No, I had no idea that was a peptide.
- [64:15]
A
Yeah, that's a, it's a bit of a ridiculous.
- [64:17]
B
I don't think, really think I've seen anybody take that and look good. I mean they, they, they look purple.
- [64:22]
A
Yeah.
- [64:23]
B
Like they get like if I, if I took melanotype, this is what people don't understand. They look at me and like, oh, he's taking Melanie Lancet. Like no, I'm not. Like, if I was taking that, you know I'd be taking that. Like I would be purple.
- [64:33]
A
Yeah.
- [64:34]
B
Doesn't it make your eyes more blue or something?
- [64:35]
A
I saw, I saw a guy that was really into peptides. He was actually one of the people that trained me early on in 2015, 16 and I saw him at a peptide conference and he walked in the room and his eyes were. Oh, he had red eyes. His blue eyes are bolding out. His skin was purple. I was like, he's been testing his own product. Clearly melanotan one or maybe melanotan two. So yes, that is a peptide. That's a 13 chain peptide. The, the hormone, it comes from the AMSH hormone that's responsible for anti inflammatory skin pigmentation. And that's the 13 Chamberlain 10 is a 13 Chan modified Melanitan 2 is a 7 chain modified PT141 for libido sexual health. Erectile dysfunction is a 7 chain from that AMSH and then KPV is at the end of the 13 chain. So it's 3 which is really good as a for pro inflammatory cytokines. Inflammatory cytokines are fighting those because of that chain. I think it really helps good with skin inflammation. Um, but to answer your question, when you take it orally, it helps with gut inflammation as well.
- [65:34]
B
Yeah.
- [65:34]
A
So that, that, that list of peptides there and actually we have one compound In Europe where it's got all of those in one capsule.
- [65:41]
B
Yeah.
- [65:41]
A
So the kpv, tb, ghkcu, you know, we have that lorazotype, we have the full listing, one capsule.
- [65:47]
B
I really feel like based on this conversation, there is a solution for almost everything. Maybe not everything, but if you are struggling with something, there might be a peptide that can help. Is there anything that you have, I don't know, come across that a peptide can't fix? I mean obviously everybody's going to die. So peptides can't quite.
- [66:12]
A
Haven't prevented death yet. No, no, we haven't found that one. I mean as I said, I work with healthy people to make them healthier. Longevity, anti aging, prevention to a degree. So there's lots of peptides in medical research at the moment. Deep in medical research. PNC 27, that's for cancer. So that's been researched at the moment. I mean, what the one peptide we haven't discussed today and so I digress a lot but there's a peptide called ARA290, that's an 11 chain amino acid and that has been shown to regenerate and fix nerves.
- [66:49]
B
Okay.
- [66:49]
A
And there's been human studies on this. This is, this might, this is the conspiracy part maybe. But you take Ara290, there's been loads of studies since early 2000s, 2010 where people struggling very badly for nerve pain and this has regenerated and fixed their nerves. Not. It's not blocked it like some of the medication would take. It's fixed it and the studies have just stopped on it.
- [67:11]
B
Yeah, that's when, that's when you know something sketchy is going on.
- [67:15]
A
I dare say I won't.
- [67:16]
B
Yeah, let's not get this video taken down. Is there any other ones we've not mentioned? We mentioned, mentioned Motsi.
- [67:26]
A
Motsi. I spoke about that at the beginning. It needs. It's. But it is, it's a really good peptide. Super potent for mitochondria, health, energy. It's an exercise mimetic and really good but has to be taken very, very carefully. Can trigger mast cells and histamine reaction. Even seem not my clients but people going to anaphylactic shock. So it shouldn't be treated like another peptide. So just make sure you work with someone that knows what they're doing and not if. If the person consulting on this peptide tells you take it every day or five days on for six weeks, just don't work with them because they don't understand peptides at a deeper level and Some people, and people listening to this have probably taken Motsi because it's trending, or some people would have done. And I say, I've been great. I took it for six weeks. I was fine. Great. Wait till the next cycle and the cycle and the cycle after that. That's when you need to be careful because you're creating that compounded effect and that your. Your. Your immune system is. Is protecting you. So the mast cell, that's what mast cells do. Right. They're like bodyguards to your immune system. So if you keep poking them, you know, eventually something might happen. So be really careful with moxie.
- [68:24]
B
Okay. And then just one thing, which I want to clear up just for myself is there's the three ways to take them. There's the injections, there's the pill form, and then there's also nasal. I'm curious to know why. Why some are specifically needed to be taken in a particular way. I mean, I know stuff that for the. The brain, it makes sense because it's just gonna. Anything you take nasally just goes straight to the brain. But the pill and the injection, will it get to a point where everything could be in pill form or do it not? Doesn't work like that.
- [69:00]
A
There's always, you know, it's 20, 26. There's always people looking for new methods to try and get away from doing subcutaneous injection. Subcutaneous injection for systemic effects seems to be the best way at the moment. Anything, Anything for the gut orally.
- [69:14]
B
Yeah.
- [69:14]
A
And anything for the brain intranasal. And of course, you've got the topical cream as well. All I'd say to people that are out there looking at all these new sort of delivery mechanisms or methodologies that are taking, like, sublingual, you know, peptides and what have you, I'm sure they have some efficacy. There's some good people that I aspire to or have a good reputation that are promoting these sort of products. But until the $30 billion insulin industry is not using it. Yeah, it's probably not that effective.
- [69:39]
B
Yeah. Okay. And then one shot stories about the nad. That's not a peptide.
- [69:43]
A
That's not a peptide? No. So that's.
- [69:44]
B
Is it commonly grouped into mistakenly?
- [69:47]
A
So, yeah. One of my frustrations. So NAD plus is a coenzyme. There is a level of signaling molecule to it, but it's not a peptide, doesn't have any amino acids. And again, when we see these peptide cheat sheets all over the Internet and they're talking about. On my peptide protocol, I'm doing NAD plus.
- [70:03]
B
And I say that's just like an immediate red flag. Like you don't have a clue.
- [70:06]
A
You don't know what I'm talking about. They do the same of SLU P332, which is an exercise memetic. And I do it. 5Amino 1 MQ. I saw a doctor this morning actually ranting on Instagram saying people, you know, miss selling these peptides. 5amino 1 MQ. And they're saying, you know, this peptide doesn't work like this. It's not a peptide. Yeah. It doesn't even have an amino acid in it. And that's what frozen. Because it's called five amino. They think it's got amino acids in, but it doesn't. It's just. Just need to do some research, have some knowledge and not just throw things out there because other people are talking about it.
- [70:32]
B
And then from just your. You're obviously an expert in this field. You are. Have almost been a guinea pig for. For yourself and trying to see what works, what's not working, what is your current protocol or the ones that you like personally for yourself.
- [70:49]
A
Yeah, I'd say, I'd say at the moment because, you know, we're at the. In the winter essentially. So Thymus and Alpha 1, which is the immune optimizing peptide. I've been taking that on and off for seven years around when I travel or seasonal depending if I'm in the UK or Dubai. So that's really good. I've not been sick sick where I've been wiped out with a sickness or proper bug since 2018. So we're pushing for. It was in the summer of 2018, so we're pushing. That was when I was in Bangkok. So we're pushing. For eight years I was tested positive for Covid, but I just had an achy quad. Yeah, so that was an odd one. So, yeah, so I, I really put that down to one along with lifestyle course I put that down to one of the reasons why I haven't got six sick Touchwood. Every time I talk about this, I'm worried I'm tempting faith.
- [71:35]
B
So that's something you've been taking every. Every winter?
- [71:37]
A
Pretty much, yeah. All round travel. You know, even if the summer I'm traveling into different climates, I just take myself personally. Again, this is not advice. I take 1.5 milligrams three times a week or every other day if I'm going to travel. When I get to the destination, I run the same sort of protocol until I leave and go back to My home country. And that seems to have helped because that's 10.
- [71:55]
B
It makes sense because I look back to the times when I've been ill and it's always around these periods of travel. I literally like after being on a long haul flight flight or something. And particularly in the like in the winter especially, I feel like in Dubai everything would be okay. But the fact that everybody from Europe comes to Dubai in the winter, they just bring all their germs and illnesses with them and just spread them to everyone. Then I end up getting it.
- [72:22]
A
Absolutely, yeah. When you're on the flights and everyone coughing, I'm like, oh yeah.
- [72:28]
B
Anything else which is noteworthy?
- [72:30]
A
Yes. And I'm running a little 37 at the moment. That's a 30, 37 chain amino acid. You run that with thymus and alpha. You shouldn't take it on its own because it's so strong it can have a. Almost have a negative effect on the immune system. It's the closest thing to an antibiotic in a peptide form and that's antimicrobial and sort of cleanse the germs. I took that for a few days. I actually felt like I was detoxing a bit on it. So I stopped that. And then since I've been here, deep sleep inducing peptide spray and of course C Max and select for all podcasts.
- [72:55]
B
Yeah, nice. So is there, is there been any horror stories or maybe sketchy incidents you've experienced with the patients, people you spoke to or even with yourself?
- [73:08]
A
Myself? No, I mean the LL37. I felt like I was going for a bit of a detoxing process. So I stopped that because I just felt, you know, when you detox feel dirty. I just, I didn't like that. So I stopped that immediately. Again, again, intuition, you know, just sometimes, you know, remember we're trying to optimize. That might mean I've got something deeper to evaluate at some point, but just not right now. I think the worst things I've seen personally with clients that I've worked with, I've got a lot of horror stories from doctors and what have you. But from clients I work with are histamine responses to growth hormone secretagogues. So they've start. This is before I had the knowledge was taking the of the CJC versus Tessa Rillin and why CJC might create a histamine response over Testamorelin and CJC 1295 I was taking it was building muscle, burning fat. Mix it, no problem. And then I had one client take it and they Got quite a few nodules, quite a few like lumps which you can get these, these just pass. And then the next they took it. And then this carried on for five days. On two days off in the following week they took it and they took a CJC injection around the right side and all the injection points came up where they'd been previously injecting. All these little nubs started popping up.
- [74:15]
B
Interesting.
- [74:16]
A
And I was like, whoa, I haven't seen that before. Yeah, this is quite a while ago. And then I understood it was just a complete mast cell response. And look, the peptides, it's not the peptide, it's the individual. Now if you've got your, your you know, DOA enzymes and optimal, you've got leaky gut and you're taking these sort of more histamine type response peptides, they're going to create a response because you're not healthy at enough to take them or your gut's not in a good enough position to take them. So we always start with the, the calming peptides, the lower peptides, the Tessamarin and KPV is really good place to start depending on who I'm working with.
- [74:45]
B
Yeah.
- [74:46]
A
So I think that answers your question.
- [74:47]
B
Yeah.
- [74:47]
A
Yeah.
- [74:48]
B
Okay then. I mean to wrap up, this all sounds very interesting and promising even for me. I'm like, what should we get started with? For, for the average person or the person who's listening, is this something that they could take into their own hands? And assuming they're purchasing good quality peptides, they can just start experimenting with themselves or go to a professional and have a discussion with them and maybe even show them some blood work and be like, hey, what, what do you think would be the best course of action for me?
- [75:24]
A
Yeah.
- [75:24]
B
Because I really just don't think most people can take this into their own hands. No, it is not going to end well.
- [75:29]
A
No, sorry I was interrupted but it'd be really irresponsible of me to say to people, buy peptides from a trusted source and start injecting yourself. Yeah, it doesn't make sense. But also, you know, just do your research on the person that you're going to be working with. You know, these are non medical professionals, but by all means work with a medical professional but make sure they have real experience. You know, there's, there's, there's lots of good doctors in all the regions in the uae, in, in obviously lots. There's one or two in Europe, one or two in the uk, a few here. Um, reach out to me and I can direct people, you know, I do the, the peptide education discovery calls. So I help people understand more about peptides and the education that I've learned for them to go on as a, as a guide. And then if they want to ultimately deal with a medical professional, then I can direct them to different doctors to work with. If that's their preference. I can tell them the blood data I like to see. Because the reason why we're looking at blood data is not to test for their peptide levels, it's to test the potential efficacy of the peptide. But this peptide probably won't work so well for. Because your guts, you've got leaky gut, or your hormones are imbalanced, you know, so. Or your kidneys are not functioning optimally even though they don't affect your liver and kidneys have the, they have to have the clearance, have to be able to. It's like an electrical circuit. If it's not optimal, then these peptides are not going to work as well. So yeah, there's. You just have. You have to do your research.
- [76:45]
B
Yeah. I think for me as well, like when I consider who I'm actually going to take advice from or maybe ask questions about, I would just look at their history and how long they've been in this game for. Like if, if they've dedicated a large chunk of their life to peptides, studying it, experimenting with it, then I'm going to listen to that person versus the person who's literally just been start to talk about it for the past six months or so.
- [77:10]
A
Absolutely.
- [77:11]
B
Yeah. Awesome. Wherever. Where can people find you?
- [77:14]
A
So we have got, well, Instagram is Dean E. Henry and then we've got Dean lab research, bionic lab.com and also UA peptides research dot com.
- [77:25]
B
Yeah. So is there physical places where people can go right now? I know there's Spot and Ibiza.
- [77:32]
A
Spot and Ibiza. At the moment that's for educational purposes. So they come in, educate them and then they can go and buy the peptides. We just go through some medical licensing there, but mostly for me it's through online websites.
- [77:44]
B
Nice. Awesome. This has been amazing. And I can't wait to turn into a superhuman in like a year or
- [77:50]
A
two after even more superhuman. So that's all we need.
- [77:53]
B
Thank you.
- [77:53]
A
Thanks, Mike. Thanks for having me.