
Naveen Jain shares his journey from growing up in rural India to becoming a billionaire entrepreneur dedicated to solving humanity’s biggest challenges. In this episode, he reveals why moonshot thinking, not small steps, is the key to innovation in health, space, and beyond. His perspective challenges every founder to think bigger about their impact on the world.
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Vivek Garipalli
Morning.
Dan Martell
One sausage McMuffin with egg please.
McDonald's Cashier
Okay, your total is.
Vivek Garipalli
Wait. Let's negotiate. How's about you throw in hash browns for a dollar?
McDonald's Cashier
Well yes sir, that price is already a dollar.
Dan Martell
Take it or leave it.
Vivek Garipalli
Take it I guess. Buy one, add one for a dollar on sausage McMuffin with egg, hash browns and more with McValue. Most locations open 5am or earlier.
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Price and participation may vary. Limited time only.
Vivek Garipalli
Valid for item of equal or lesser value. Ba da ba ba ba.
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Dan Martell
So Naveen, this is my first question because you didn't want to know and I love that. But I want to be a billionaire. How can I be a billionaire and is it just about focusing on money?
Vivek Garipalli
So first of all, making money is simply a byproduct of doing things that help other people's lives. So if you can build any product, any service that helps a billion people live a better life, you can create a $100 billion company. But you never wake up in the morning and say what should I do to create a billion dollar company? It is like having an orgasm. If you focus on it, you're never going to get it. So just enjoy the process.
Dan Martell
I've never heard that before said that way and I love it. So you came to America with $5. What was the moment that you realized or you said to yourself, I will never be poor again.
Vivek Garipalli
You never. Honestly, anyone who tells you that there was a particular moment that changed their life. It's rarely two. It's like telling someone that it is the last straw that broke the camel's back. It is really all the straws that came before that is what breaks the camel's back. So our life is really these strings of experiences. And every single moment in your life makes you a different person. Every conversation, every interaction changes who you become. And one day you wake up and someone who has not seen you for 20 years, you say, oh my God, you're such a different person. And you live with a person like your spouse and you say, you are still the same that I married 20 years ago.
Dan Martell
So how do you deal with that? Because I've seen that too, right? You know, you go back to see people that you grew up with and you realize you have nothing to say or even maybe because of your success and fame and notoriety, they just don't want to talk to you anymore.
Vivek Garipalli
Well, you know, to be honest with you, you can't control what other people think. You can't control what other people say. You can't control the world around you. But what you can control is how you react to it. So it's your job to make them feel comfortable. It's your job to make them feel that they're still this. You are still the same person and you still care about the same thing and your friendship still matters. I mean, the fact is, when I came here, the people I knew at that time, I are still the same people I know today. There's nothing had changed. This idea, Dan, that I have heard time and time again, that money makes you an asshole, I can tell you that's completely not true. You have to be an asshole to begin with. And money simply allows you to become who you were to begin with. And if you were a good human being, money doesn't make you a bad person. If you are a terrible human being, money just simply allows you to be terrible now.
Dan Martell
Amplifies.
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Right.
Dan Martell
What do you think? That is the biggest misconception around either a founders who have created billion dollar companies, unicorns, whatever, or just billionaires in general.
Vivek Garipalli
As I said, money doesn't make people what they are. The misconception that I think it's a common thing everyone knows there is no such thing as overnight success, you know, and behind every success there is years, if not decades of hard work that goes into it. And one day you wake up and say, oh my God, I can't believe that company is so successful without realizing someone has been slogging away day in Day out. Right. People think the success is a straight line forward. And more of us who have been a founder realize as a founder, you live like you're alive. And how do you know you're alive? You, you have a heartbeat. What does a heartbeat look like? It goes up and down and up and down. When it's smooth, you're dead. So the day you find yourself living a smooth life, you're chosen to live a life of a dead person. These ups and down tells you that you're still alive. When you're on top of that beat, you always, never become too cocky because you know the winter is coming. And when you are at the bottom of the beat, you never, ever worry because you know the next beat is going to be the upbeat.
Dan Martell
I always think to myself that, you know, it's not that people can't be an entrepreneur, anyone can. But I think if you're going to be successful, it's a very small. Because of those ups and downs, it's so hard. So what was for you? Obviously, you know, building billion dollar companies and, and really being at the forefront. I'm sure you've had some dark moments. Like you said, those down moments, maybe what was a moment for you or maybe you were like, I'm just going to give up. This is too much.
Vivek Garipalli
Yeah. You know, to be honest with you, this is one of the things that come from my eastern philosophy that when things happen, it is when we label them as good or bad is when you start to feel good or bad. When things happen, you simply say, that happened. And, and what am I supposed to do with that now? Right. So think of it as everything you do in life is an experiment and there is no success and there is no failure. An experiment has an outcome A or outcome B. When outcome A happens, you do C and D. When outcome B happens, you do E and F. And when you do, each one of them allows you to take the next step. And that's what entrepreneurship is all about. You take the next step, it gives you two more possibilities and you take the next route and gives you two more possibilities and you keep moving forward. And that is really what the life is all about. There is no up and down. There is no success, there is no failure. And I can give you the stories. In every culture, there is a story about do you think it's good or bad? So in Indian culture, there's a story about a king and his wise men. So they go out on a forest to hunt and the king falls down from his horse and lowe's knows that.
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Dan Martell
BRICS is on one of the biggest.
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Vivek Garipalli
And the wise men say, so that happened. And well, it's probably good. And the king is so angry and says, what do you mean so it is good? And he puts the wise man into the dungeon. He said, now let me show you what that is, what that good means. And he said, so that happened. It's good. And now the king goes off to the the forest again and goes hunting. This time he gets caught by the native tribe and they catch him and they want to sacrifice him. So they get him ready for sacrifice and the priest comes and priest says, let him go. Why? We don't sacrifice a broken man in front of the God. We only sacrifice a man that's not broken. Let him go. He's a broken owl. He has a broken owl. He goes home and he goes to the wise man and he says, oh my God, you were so right. That was so good and that you saved my life. The wise men said, no, I'm so glad it was so good that you put me in a dungeon because you saved my life. If I was with you, they would have sacrificed me, right? The point is there is no such thing. Good or bad. Good or bad, you may not know for years to come. So when the moment happens, you believe the universe is your friend and everything that's happening is for your good and you keep moving forward.
Dan Martell
You know, something I gathered from what you just said was enjoying how you feel in those moments because I think for me, I get trapped in the feeling, right? It's not necessarily what's happening, it's the feeling. Anxiety, fear. If you tell yourself, if your mind says, you know what, that fear is actually a nice feeling, it feels good, then it feels good and doesn't create anxiety. And I'm sure I've hear, we've had some guests on talk about how anxiety and all this stuff can cause like really difficult, you know, our body can just die basically from stress and everything.
Vivek Garipalli
That could, you know, and it creates, and it creates a loop that allows you to spiral down because just by labeling that this is bad thing, just simply labeling it bad, it allows you to Spiral down. If you say, well, universe is my friend. If this happened, it's probably for my good, suddenly you say, oh my God, look at all the goodness that's coming out of that experience that I had. The girlfriend that I thought that broke up with me was going to be end of my life. And I'm thinking, oh my God, what a nightmare I avoided.
Dan Martell
That is true. That is true. So since you're talking about, you know, somebody breaking their arm, I'm very fascinated with how AI and emerging technologies are transforming healthcare. It's one of the most exciting, exciting things I'm finding when it comes to technology. And you said illness can be optional. So what is. What does that even mean? Because I imagine that people are shocked when you say that. And is there something that you're finding that is shocking about what we can solve?
Vivek Garipalli
Absolutely. So first of all, then, we all believe being healthy is a choice. You agree, right? If being healthy is a choice, don't you think the reverse of that, that means being sick is also a choice? And that's what I mean. What if the illness was optional? And so that means is, can we provide people with insights and information of why, what is going on in their body, why it is happening, and what can they do about it so that they don't have that particular disease? Now, it's up to you to follow that guidance or not to follow the guidance. That's what I mean. Illness is optional. You tell people smoking is bad and you take the thing and people say, I'm going to light up the cigarette and smoke. Well, that's your choice. So being sick is a totally a choice you make. So the interesting thing about being a founder is your liabilities generally tend to be your assets. And I'm going to expand on that because if this is one concept, if I can teach entrepreneurs, that would change their life. Asking you, as an entrepreneur, the problems you solve are the questions you ask. So what questions are you asking that no one else is asking? By simply changing the question, it changes the problem. Right? So let me give you two examples. When I started Biome to actually say, look, what if we can actually understand what changes in the human body at the onset and during the progression of these chronic diseases? If we can find out what happens, then we will be able to diagnose them early, prevent them from happening, and, God forbid, outright reverse them. But what I noticed was that every single company in the industry, they were experts and they were looking at your DNA and your genes, and I thought, oh my God, why is it I am not a scientist. My first question was does your DNA change when you develop a chronic disease? So for example, you do my DNA test and I gained 200 pounds. Has my DNA changed? No. Now I have diabetes. Has my DNA changed? No. Now I have depression. Has my DNA changed? No. Then I get a heart disease. My DNA does not change. Then I die. And you look at my DNA hundred years after I die. It's identical DNA. So if DNA can't even tell you you're dead or alive, how will it ever tell you you're becoming healthier or sicker. So I realized the things that are changing is your gene expression or your rna, but not your DNA. So why not measure?
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Vivek Garipalli
Way to hire and that was my number one breakthrough. Number one breakthrough was I started to look at what is happening in the human body and it turns out then that 99% of all the genes in our body don't come from mom and dad. They come from these microbes that live in our gut, in our mouth, and all over us. 100 trillion microbes. And I start googling Parkinson's and microbiome, heart disease and microbiome depression and microbiome. It turns out that microbiome is involved in all these different diseases. And then it occurred to me, there are 10 companies doing microbiome testing. And then why is this problem not getting solved? But turns out every microbiome company until we started and to date, there's no. Every microbiome company simply tells you what organisms are in your gut. And we thought, wait a sec, it doesn't matter what organisms are there. What matters is what are they doing? Are they doing good things, are they doing bad things? It's like in my mind, these microbiome is like a tiny, tiny people. If you put them in a good environment, good behavior, you put them in the bad environment, the bad behavior. So why not focus on what they are doing, not who they are? And that changes everything. And all I had to do was find the technology that can allow me to do that. So not being an expert, my first thing was why not do the RNA testing? And every expert told me it can't be done. As an entrepreneur, I don't know if can or cannot be done. I'm thinking, if that's what we need to do, we're going to find a way to do that. Turns out at Los Alamos National Lab, they were working on a bioweapon and biodefense project, actually trying to understand what these organisms do and how they interact with the human body to create antidote for biological bomb. Guess what? I took that technology exclusive license. Started Wyoming eight years later. Brother. We have now analyzed 1 million people and collected over 100 quadrillion data. And when you do a test, I take a split of your saliva, four drops of your fingerprint, blood, and a touch of your stool, and I analyze for 100 million biomarkers, not hundred biomarkers, 100 million biomarkers. I can tell you now everything that's happening in your body. Your biological age, your cognitive health, your heart health, your immune health. But more importantly now, I look at the stuff and that's happening in your body and I tell you why it is happening. So Dan says, look, I've had constipation for a long time. What should I do? And my answer is, I don't know. I analyze your body and I say the reason you have constipation is the you have a high methane gas that's slowing the motility down and this is what you can do. Or do you have a low butyrate or do you have a low sulfite or do you have a high bile acid or do you have a low serotonin? So once we know the underlying root cause, then we can tell you what to do about that. And so what we do is we tell you don't eat avocado right now Dan, because your uric acid production is too high. You're going to get up gout. Or don't eat spinach or ox or almonds because your oxalates are too high. Or don't eat broccoli because your sulfide is too high. But you can eat red meat if you want because choline and carnitine in the red meat is not microbiome is not making tma, that's your liver is not converting them to TMAO which is causes the heart disease. So we can tell you what foods to eat and why and give you a science paper for it. What foods not to eat and why and give you science paper for it. Then we tell you every nutrition your body is lacking, what vitamin, minerals, herbs, and we custom make it for you. We make you personalized probiotics, we give you personalized oral lozenges, we make a personalized toothpaste. And when you follow that, we did double blinded placebo controlled studies that shows 64% of the people who had IBS, 15% of us suffer from it. 64% of the people in 90 days became healthy compared to 10% on placebo people who were pre diabetic. Their A1C came down by 0.42 in 90 days from pre diabetic they became healthy. Now imagine depression and anxiety. We were talking about anxiety. Down by over 70% in the people in the intervention group compared to the 28% on placebo. So now imagine a person who had no knowledge of the science and biology simply asking a different question as a founder, putting together, assembling a team of experts and challenging them to do the things they thought was not possible. Eight years later, we have helped a million people live healthier and longer. Now we are just beginning, right? Imagine what you can do. The second thing is my liability was what? I am born in India, I speak with a thick Indian accent. Everyone thought I should learn to speak just like everyone else. And my thinking was no. That is how I control the room I go walk into. If you are, if I am in the room, you can't be multitasking and make any sense of what I'm saying. So you have to give me 100% of your attention. That is my asset. Now that when I walk into the room, everyone gives me 100% of their attention. So my liabilities become my asset.
Dan Martell
Hey, I like that. I've tried to do a British accent. I tried to do other accents. It sounds terrible, by the way. So I'm curious, based on this data that you've seen, what would you say is the biggest lie that we've been told about our bodies? And how is science and the things that you're doing proving it wrong?
Vivek Garipalli
So, number one thing, we were told that these are the food, the broccoli, the spinach. Remember that, Pop? I told you the spinach is good for everyone. Everyone should take a spinach, right? What we are, what we learned is there's no such thing as universal healthy food. A food that's good for one person may not be good for another person. What we find is 45% of the people are harmed by eating spinach because of the oxalate degradation. 42% of the people are harmed by eating broccoli and cabbage and brussels sprout. Think about that. 37% of the people are harmed for eating avocado. This was something I would have never thought is basically, we all knew what Hippocrates says 2500 years ago. All diseases begin in the gut. Let food be thy medicine. Let thy medicine be the food. And one man's food is another man's poison. That's it. I mean, that's really what we learned. There is no such thing as universal healthy food. There is no such thing as universal healthy supplements. So if people are saying everyone should take nad, guess what? Unless your name is everyone, just don't do it. Because NAD can be good for some people, or NAD can actually cause the progression of cancer, Right? So don't take these things because they are medicine. You won't take a medicine just because. So don't think of food and supplements as anything but a medicine. So test, don't guess.
Dan Martell
Test, don't guess. I feel like I need to throw out everything I've known. Like, everything I've known just needs to be thrown into the trash. And I need to do this test. My final question for you, and I love. I'm, like, blown away. We need, like, three hours of our time to keep going. But based on what you know about technology, advancements in technology, you've done so many different industries. If you had to start over tomorrow with something totally brand New and you were going to build a totally brand new billion dollar company, what would it be?
Vivek Garipalli
Look at any problem today you see that is impacting a billion people, 100 billion people. If you can solve that problem, you have a massive company, right? So you look at energy, you look at food, you look at agriculture, you doesn't matter which industry. Healthcare is a $4 trillion economy just in US alone. Every one of these company, every one of these things we call social problems are the entrepreneurs waiting for some entrepreneur to solve them. Non if you want to do a small good in the world you do a non profit. If you want to do a large good in the world, you do for profit company because profit is the engine that allows you to do more good in this world. World. So do good and do well. That is my philosophy and I really believe in the next five years that health care will be delivered at home using AI because they will know more about your internals of the body using the test like wyom, right. And they will use AI to tell you exactly what to do that your doctors will know. So med the health care of the healthcare will be delivered at home and the pharmacies are going. It's not going to be the pharmacies that deliver the medicine, it's going to be the farms that deliver the medicine. So the medicines of the future are going to come from pharm, not a pharmacy.
Dan Martell
Do good. Sorry, say it one more time.
Vivek Garipalli
Doing good and doing well.
Dan Martell
Doing good and doing well. I love that. This has been amazing. The farm is the pharmacy. Don't worry when I quote this I'm going to put your name on there. I swear if people want to get in touch with you, they obviously, I mean everyone like you said, a billion people, they need this. 8 billion people, 6 billion people. How can they do so please go.
Vivek Garipalli
To ym.comv as in Victor I O M E.com the reason I'm spelling is because people from India can't pronounce the word V. So I always say V as in Victor I O M e dot com and please go do the test. It will help you, it will help your family and it will help the billions of people live a better life. So please spread the word.
Dan Martell
Well the next time we do an interview I'm going to first talk about what came about from this and I'm going to, I'm going to do a follow up every week. How's that? This is going to be. I'm fascinated because I got a lot of stomach problems and I got a lot of I got a lot of problems that maybe that's why I was negative before we talked. But now I don't have problems because I'm enjoying the ride and my mind is switched now. So thank you for that. I needed this conversation today. I oddly enough. But this has been amazing. Viome, viome. Everyone needs it. Go and get it. But I'm super inspired by what you've done and thank you for joining us.
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Vivek Garipalli
First of all, Dan, I want to thank you for two things. Thank you for doing what you do because stories of every founder inspires other people to go out and solve bigger and bigger problem. So what you're doing, I want to my hat's off to you because you inspire everyone to go out and solve a massive problem and that means humanity will be better because of every single founder who goes out and solves a problem.
Dan Martell
You might be the kindest, most humble.
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Person I've ever had a chance to speak to.
Dan Martell
That's amazing, you know. Thank you. So you gotta come back in a couple months. You're coming back.
Vivek Garipalli
Promise. Promise you that.
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Is it time to reimagine your future? The right business skills may make a difference in your career. At Capella University, we offer a relevant education that's designed to focus on what you need to know in the business world. We'll teach professional skills to help you pursue your goals like business management, strategic planning and effective communication. And you can apply these skills right away. A different future is closer than you think with Capella University. Learn more at Capella. Edu.
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Lowes has the Labor Day deals you need to give your home a new look. Buy one get one free select interior paint via Visa gift card rebate then add the final touch with two for $8 on select 2.5 or 3 quart mums. Refresh your home and save big while doing it loaves. We have help you Save valid through 93 mums offer in store only. Selection varies by location while supplies last. More terms and restrictions apply. Seeloads.com rebates for details.
Guest: Naveen Jain, Founder of Viome
Host: Dan Martell & Vivek Garipalli (IBH Media)
Date: August 21, 2025
In this inspiring episode, serial entrepreneur Naveen Jain shares his journey from arriving in America with only $5 to creating billion-dollar ventures like Viome, which is pioneering hyper-personalized healthcare. Jain and the hosts discuss the true nature of success, why purpose must precede profit, misconceptions about entrepreneurship and wealth, and how technology—especially AI and microbiome science—are poised to revolutionize health at a fundamental level. Naveen also offers deep wisdom on mindset, resilience, and why what many founders see as liabilities can become their greatest strengths.
“Making money is simply a byproduct of doing things that help other people's lives. If you can build any product, any service that helps a billion people live a better life, you can create a $100 billion company.” (Vivek, 02:01)
“If you focus on it, you're never going to get it. So just enjoy the process.” (Vivek, 02:16)
“It's really all the straws that came before that is what breaks the camel's back... every conversation, every interaction changes who you become.” (Vivek, 02:40)
“Money doesn't make you an asshole, you have to be an asshole to begin with. Money simply allows you to become who you were.” (Vivek, 04:11)
“There is no such thing as overnight success…behind every success there is years, if not decades, of hard work.” (Vivek, 04:49)
“When it's smooth, you're dead. The day you find yourself living a smooth life, you've chosen to live a life of a dead person.” (Vivek, 05:18)
“When things happen, you simply say, that happened. And, and what am I supposed to do with that now?... There is no success and there is no failure. An experiment has an outcome A or outcome B.” (Vivek, 06:25)
“Good or bad, you may not know for years to come. So when the moment happens, you believe the universe is your friend and everything that's happening is for your good and you keep moving forward.” (Vivek, 12:05–12:11)
“Just by labeling that this is bad thing ...it allows you to spiral down. If you say, well, universe is my friend... look at all the goodness that's coming out of that experience.” (Vivek, 12:49)
The Provocation:
Jain claims that much chronic disease is preventable—and potentially reversible—by understanding the body, especially the microbiome.
“Being healthy is a choice... So being sick is a totally a choice you make.” (Vivek, 13:55)
Innovation Through Different Questions:
Jain’s breakthrough came from asking what actually changes in disease—gene expression, not the DNA itself.
“If DNA can't even tell you you're dead or alive, how will it ever tell you you're becoming healthier or sicker?... The things that are changing is your gene expression or your RNA, but not your DNA.” (Vivek, 15:34)
The Microbiome Breakthrough:
Instead of just cataloguing microbes, Viome looks at what they are actually doing—using technology spun out of Los Alamos National Lab.
“What matters is what are they doing? Are they doing good things, are they doing bad things?... Why not focus on what they are doing, not who they are?” (Vivek, 18:10)
Radical Personalization:
Viome analyzes 100 million biomarkers to provide unique nutrition, supplement, and health recommendations—including custom-formulated probiotics and toothpaste.
“We tell you what foods to eat and why and give you a science paper for it. What foods not to eat and why... Every nutrition your body is lacking, what vitamin, minerals, herbs, and we custom make it for you.” (Vivek, 20:45)
Outcomes:
Results from placebo-controlled trials:
Liabilities as Assets:
Jain reframes his accent as a feature, not a flaw.
“That is how I control the room... you have to give me 100% of your attention. That is my asset.” (Vivek, 22:25)
“What we learned is there's no such thing as universal healthy food. A food that's good for one person may not be good for another person... 45% of people are harmed by eating spinach… 42% broccoli… 37% avocado.” (Vivek, 23:27)
“So don't think of food and supplements as anything but a medicine. So test, don't guess.” (Vivek, 24:38)
“Every one of these things we call social problems are the entrepreneurs waiting for some entrepreneur to solve them… If you want to do a large good in the world, you do for profit company because profit is the engine that allows you to do more good in this world.” (Vivek, 25:35–26:01)
“The medicines of the future are going to come from pharm, not a pharmacy.” (Vivek, 26:36)
“Do good and do well. That is my philosophy.” (Vivek, 26:51)
“Go to viome.com. V as in Victor, I-O-M-E dot com...please go do the test. It will help you, it will help your family and it will help the billions of people live a better life.” (Vivek, 27:11)
“Money doesn't make you an asshole, you have to be an asshole to begin with. Money simply allows you to become who you were.” (Vivek, 04:11)
“When it's smooth, you're dead. These ups and down tells you that you're still alive.” (Vivek, 05:18)
“Being healthy is a choice... So being sick is a totally a choice you make.” (Vivek, 13:55)
“There is no such thing as universal healthy food... One man's food is another man's poison.” (Vivek, 23:27)
“The medicines of the future are going to come from pharm, not a pharmacy.” (Vivek, 26:36)
“Do good and do well. That is my philosophy.” (Vivek, 26:51)
This episode is a goldmine for aspiring founders and changemakers—a rare blend of practical lessons in business and health tied together with deep, actionable philosophy. Jain’s insistence that “illness is optional,” the emphasis on personalized health, and his reframing of setbacks into opportunities, will leave listeners empowered to challenge the status quo in any field. To those ready to rethink both their health and their ventures, “test, don’t guess”—and aim to do good and do well.
For more: Visit viome.com and continue following the Founder’s Story Podcast for more transformative conversations.