Here's the Scoop: Are GLP-1 Medications Okay for Children's Use?

Release Date: July 21, 2025

Introduction to Pediatric Obesity and GLP-1 Medications

In this episode of "Here's the Scoop," host Yasmin Vossoughian delves into the pressing issue of pediatric obesity and the emerging use of GLP-1 medications as a treatment option. Highlighting findings from a study published in Nature Medicine, Yasmin discusses how certain genetic variants can increase the risk of obesity in children. This genetic insight has led some parents and their children to consider genetic testing and, subsequently, the use of GLP-1 medications like Wegovy and Saxenda.

Expert Insights with Dr. Casey Berman

Yasmin is joined by Dr. Casey Berman, a pediatric endocrinologist at Hassenfeld Children's Hospital at NYU Langone, who specializes in diabetes care for children and teens. Dr. Berman provides valuable perspectives on the use of GLP-1 medications in pediatric populations.

• Rising Prescriptions Amid Obesity Epidemic
  Dr. Berman explains the surge in GLP-1 prescriptions:
  “I definitely am. So I think this has been in response to the rising, you can call it, obesity epidemic, where the rates of obesity have really been increasing.” ([02:07])

• Criteria for Prescribing GLP-1 Medications
  She outlines the criteria for prescribing these medications:
  “We reserve these medicines for those in Class 2 or Class 3 obesity, especially if they have comorbidities like prediabetes or high cholesterol.” ([02:47])

• Long-Term Use and Safety Concerns
  Addressing concerns about prolonged medication use, Dr. Berman states:
  “Obesity is now thought of as a chronic condition. It's something a lot of people will live with long term.” ([03:56])
  She further reassures that studies have shown no negative impact on growth and puberty over at least one year of use.

• Importance of Lifestyle Interventions
  Emphasizing a holistic approach, she says:
  “It's important to stress that when starting one of these medications, it really needs to be a combination of interventions. Most importantly, first and foremost is the healthy lifestyle changes.” ([04:48])

Patient Story: Morgan and Florence

To shed light on the real-life impact of GLP-1 medications, Yasmin introduces Morgan, a 13-year-old patient, and her mother Florence.

• Morgan's Transformation
  Morgan shares her experience:
  “I lost about 56 pounds... I feel way more active and comfortable now.” ([10:30])
  She mentions initial side effects like fatigue and nausea but highlights significant improvements in her daily life.

• Florence’s Perspective
  Florence discusses their decision-making process:
  “We tried dieting and it didn't work, so we sought medical help.” ([12:28])
  She emphasizes the importance of seeking professional assistance when lifestyle changes alone are insufficient.

• Sustaining Weight Loss
  Morgan expresses confidence in maintaining her weight loss:
  “I think I definitely have more control on, like, what I eat now and stuff. So I think I'd be okay if I stopped taking it.” ([12:37])

Key Takeaways

• Effectiveness of GLP-1 Medications:
  GLP-1s can be a valuable tool for children with severe obesity, especially when combined with lifestyle interventions.

• Safety Profile:
  Current studies indicate that GLP-1 medications do not adversely affect growth or puberty in children over at least one year of use.

• Need for Further Research:
  While promising, more research is necessary to understand the long-term effects of GLP-1 use in both children and adults.

Headline Highlights

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Conclusion

In this episode, "Here's the Scoop" provides an in-depth look at the use of GLP-1 medications in treating pediatric obesity, featuring expert opinions and personal stories that highlight both the potential benefits and the considerations involved. Additionally, the episode covers a range of current headlines, ensuring listeners are well-informed on significant global and cultural events.

Thank you for tuning into "Here's the Scoop" from NBC News. Stay informed and join us again tomorrow for more insights on the stories that matter.