If you are eating well, exercising, and still gaining belly fat, losing mental sharpness, and waking up exhausted, your mitochondria are likely the missing piece. This is not a willpower problem. It is a cellular energy problem, and it starts earlier than most doctors will tell you.

In this episode, I sit down with Siobhan Mitchell, neuroscientist and mitochondrial health researcher, to explore how oestrogen loss disrupts mitochondrial function and why your gut microbiome plays a bigger role in oestrogen recycling than most women realise. We also cover S-Equol and why it is one of the most powerful compounds for perimenopause belly fat, brain fog, and night sweats. If you are looking for real answers on why your body feels different in your 40s and what you can actually do about it, this episode is for you.

WHAT YOU’LL LEARN

• Why belly fat shifts to your middle during perimenopause

• How the estrobolome recycles estrogen through your gut microbiome

• What S-Equol is and how it reduces brain fog, belly fat, and night sweats

• The difference between estrogen alpha and beta receptors and why it matters

• Why estrogen loss causes joint pain and frozen shoulder in perimenopause

• How NAD+ decline affects your energy and mitochondrial function after 40

• How chromium helps with blood sugar spikes and food cravings in perimenopause

TIMESTAMPS:

VALUABLE RESOURCES

• Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it.

👉 https://biosyncing.scoreapp.com/

A BIG thank you to our sponsors who make the show possible:

• MitoQ - Support your cells at the source with MitoQ NAD Plus Dual Action, designed to boost NAD levels and help your cells actually use them for steady energy and sharper focus

👉 https://www.mitoq.com and use code ANGELA for 10% off your first order.

ABOUT THE GUEST

Dr. Siobhan Mitchell is Chief Scientific Officer at MitoQ and holds a PhD in neuroscience with a postdoctoral fellowship in brain ageing from the University of Washington. She specialises in mitochondrial health and healthy ageing, with a particular focus on how estrogen loss affects cellular energy, metabolism, and brain function in women during perimenopause and beyond.

LinkedIn: https://www.linkedin.com/in/ellen-s-mitchell