The Week in Diabetes & Endocrinology — Episode 002 | April 10, 2026

From Hormone Insight (hormoneinsight.com)

Six stories this week that endocrinologists, diabetologists, and internists need to know.

TIMESTAMPS:

0:00 — Introduction & This Week's Stories

1:30 — EZ-PAVE: LDL Under 55 Beats Under 70 in ASCVD (NEJM)

7:00 — CMS BALANCE Model: Medicare Covers GLP-1 for Obesity

11:00 — GZR4: Second Once-Weekly Insulin Beats Glargine AND Degludec

14:00 — CagriSema NMA at ACC 2026: Best Efficacy AND Tolerability

16:30 — BP Variability Predicts Dementia in Type 2 Diabetes (ADVANCE)

19:00 — Blood-Flow Restriction Training Boosts Mitochondria in T2D

21:00 — Closing Thoughts

REFERENCES & SHOW NOTES:

▸ EZ-PAVE (NEJM): https://doi.org/10.1056/NEJMoa2600283

▸ CMS BALANCE Model: https://www.cms.gov/priorities/innovation/innovation-models/balance

▸ GZR4 SUPER trials: https://www.prnewswire.com/news-releases/gan--lee-pharmaceuticals-once-weekly-basal-insulin-gzr4-injection-meets-primary-endpoints-in-two-pivotal-phase-3-clinical-trials-super-1-and-super-2-302730104.html

▸ CagriSema NMA (DOM): https://doi.org/10.1111/dom.70667

▸ ADVANCE BP variability (JAHA): https://doi.org/10.1161/JAHA.125.044061

▸ BFRT in T2D (Cell Metab): https://doi.org/10.1016/j.cmet.2025.12.016

ABOUT THIS PODCAST:

A weekly evidence-based review of the top stories in diabetes, obesity, thyroid, and endocrinology — modeled on Medscape's "This Week in Cardiology." New episodes every Thursday. For healthcare professionals.

▸ Website: https://hormoneinsight.com

▸ Full show notes: https://hormoneinsight.com/podcast

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️ This content is intended for healthcare professionals. It does not constitute medical advice for patients.

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