The Week in Diabetes & Endocrinology — Episode 004 | April 24, 2026

From Hormone Insight (hormoneinsight.com)

Six stories this week that endocrinologists, diabetologists, and internists need to know.

TIMESTAMPS:

0:00 — Introduction & This Week's Stories

1:15 — Tzield (Teplizumab) FDA Expanded to Age 1+ for Stage 2 Type 1 Diabetes

5:30 — AACE 2026 Annual Meeting in Las Vegas: What's Worth Watching

8:30 — Orforglipron ATTAIN-1 Subgroup: Consistent Weight Loss Across Every BMI

12:00 — First Generic Dapagliflozin Arrives: Cost and Access Implications

15:00 — GLP-1 Receptor Agonists and Erectile Dysfunction: Signal or Noise?

18:00 — AACE Thyroid Ultrasound Finding: A New Clue for Indeterminate Nodules

20:00 — Closing Thoughts

REFERENCES & SHOW NOTES:

▸ Tzield (teplizumab-mzwv) sBLA FDA approval: https://www.sanofi.com/en/media-room/press-releases/2026/2026-04-22-05-05-00-3278650

▸ AACE 2026 Annual Meeting, Las Vegas (April 22–24): https://pro.aace.com

▸ Orforglipron ATTAIN-1 BMI subgroup (AACE 2026): https://www.endocrinologyadvisor.com/reports/orforglipron-weight-loss-bmi-categories/

▸ First generic dapagliflozin FDA approval: https://www.fda.gov/drugs/drug-alerts-and-statements/fda-approves-first-generic-dapagliflozin-tablets

▸ GLP-1 RA and erectile dysfunction target-trial emulation (eClinicalMedicine): https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00104-5/fulltext

▸ AACE thyroid ultrasound presentation (post-microcystic reflection in indeterminate nodules)

ABOUT THIS PODCAST:

A weekly evidence-based review of the top stories in diabetes, obesity, thyroid, and endocrinology — modeled on Medscape's "This Week in Cardiology." New episodes every Thursday. For healthcare professionals.

▸ Website: https://hormoneinsight.com

▸ Full show notes: https://hormoneinsight.com/podcast

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️ This content is intended for healthcare professionals. It does not constitute medical advice for patients.

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