On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26.

Host: Daniel Griffin and Sarah Dong

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Links for this episode

Viral
Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM)
Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID)
Bacterial
Eagle effect (Wikipedia)
THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM)
Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection)
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine)
Caring for Adult Patients With Sepsis (JAMA)
Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine)
Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine)
Caring for Pediatric Patients With Sepsis (JAMA)
ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians)
Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA)
Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications)
Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases)
Fungal
The Last of US Season 2 (YouTube)
Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID)
Clinical and Radiological Predictors of Invasive Fungal Sinusitis (OFID)
Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness (JID)
Can fluconazole be used to treat non-resistant Candida (Candidozyma) auris infections? Preclinical PK/PD data from a Galleria mellonella infection model (JID)
Parasitic
Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial (LANCET: Infectious Diseases)
Miscellaneous
Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-Related Career Decisions in Infectious Diseases (OFID)
Number Needed to Treat (NEJM)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

Infectious Disease Puscast #103