On episode #105 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/9 – 4/22/26.

Host: Daniel Griffin and Sarah Dong

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Links for this episode

Viral
Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients (NEJM)
Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir (NEJM)
Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP)
Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection (NEJM)
A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage (JID)
First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID)
Bacterial
Tetanus Surveillance — United States, 2009–2023 (CDC: MMWR)
Notes from the Field: Tetanus in Four Children — Idaho, Minnesota, Missouri, and Wisconsin, 2024 (CDC: MMWR)
Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults (JAMA)
Efficacy and safety of vancomycin versus 13 alternatives in MRSA-confirmed skin and soft tissue infections: a meta-analysis of 39 randomized controlled trials (Infection)
Methicillin-Resistant Staph Aureus (MRSA) Nasal Swab Utilization as a Predictor for MRSA Skin & Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID)
Practice variation, outcomes and definitions of suppressive antimicrobial therapy for prosthetic joint infections: a systematic review and expert consensus statement (CIC)
Efficacy and safety of VPM1002 and Immuvacin preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial) (BMJ)
Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis (CID)
Do C-Reactive Protein Measurements Predict Treatment Failure in Native Vertebral Osteomyelitis? (OFID)
Fungal
The Last of US Season 2 (YouTube)
Rising burden of severe pediatric coccidioidomycosis: a 25-year single-center study (Journal of the Pediatric Infectious Diseases Society)
Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024 (CID)
Test Performance and Clinical Utility of the cobas® eplex Blood Culture Identification Fungal Pathogen Panel (OFID)
Cutaneous Paraconiothyrium cyclothyrioides Infection in Lung Transplant Recipient, Georgia, USA (Emerging Infectious Diseases)
Azole Resistance in Aspergillus fumigatus From Diverse Environments in Ohio, United States, Is Primarily Driven by TR34/L98H and TR46/Y121F/T289A Environmental Signatures (OFID)
Parasitic
Fatal Donor-Derived Disseminated Acanthamoeba Infection in a Liver Transplant Recipient (OFID)
Miscellaneous
Host–microbiome archetypes differentiate infection from pathogen carriage in the human lower airway (Nature Communications)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

Infectious Disease Puscast #105