On this episode of inSpired, Mike Rockefeller, Co-Chief Investment Officer of Woodline, sits down with Dr. Leonard Schleifer, Co-Founder, President & CEO of Regeneron, at its headquarters in New York.

Len reflects on the 38-year journey of building Regeneron alongside co-founder Dr. George Yancopoulos, the company's deep pipeline, and the extraordinary story of treating President Trump for COVID-19.

They explore the growth runway for Eyela and Dupixent, its late-stage pipeline spanning obesity, multiple myeloma, anticoagulation, and the C5 franchise, as well as the Regeneron Genetics Center, curing genetic deafness, AI in drug discovery, and the company's disciplined M&A philosophy.

A candid take on science-first drug development and what it takes to succeed in the biotechnology industry going forward.

This is inSpired.

Recorded May 6, 2026.

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00:00 inSpired with Dr. Leonard Schleifer
01:49 Founding Regeneron in 1988
08:04 Working with Dr. George Yancopoulos
11:44 Top Moments and the EYLEA Approval
15:05 Treating President Trump for COVID
19:22 EYLEA and EYLEA HD Today
20:18 Dupixent and the Type 2 Franchise
23:20 Next Generation Immunology
29:39 Obesity: A GLP That Lowers Cholesterol
33:42 Lynozyfic in Multiple Myeloma
34:50 Factor XI Anticoagulation
39:46 The C5 Franchise
42:48 The Regeneron Genetics Center
48:06 Curing Genetic Deafness
50:03 AI in Drug Discovery
52:17 M&A Philosophy
55:47 Succession and Advice for the Next Len

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Mike Rockefeller is the Co-CIO of Woodline® Partners LP ("Woodline"), manager of the Woodline | Spire funds. All opinions expressed by Mike and podcast guests are solely their own opinions and do not reflect the opinion of Woodline.

Guests appearing on this podcast may maintain, or may have maintained, business relationships with Woodline or its affiliates. The views expressed by any guest do not constitute an endorsement or testimonial of Woodline.

This podcast is for educational and informational purposes only, is not directed at any investors or potential investors in any Woodline fund and should not be relied upon as a basis for investment decisions. Funds managed by Woodline, including the Woodline Spire℠ funds, may maintain positions in the securities discussed in this podcast. Any discussion of the past performance of any investment, sector, or market is not indicative of any future results.

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Episode Credits:
Directed by & Artwork Designed by: Brian Thompson / BT Design & Creative
Produced, Edited, and Mixed by: Dillon Mortensen Films
Music Licensed through: Epidemic Sound