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As the holidays approach, I want to say welcome and thank all of my good friends for coming back to the Juice Box Podcast over and over again.
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Hi there, my name is Sarah and I officially have latent autoimmune Diabetes of adulthood.
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This is part two of a two part episode. Go look at the title. If you don't recognize it, you haven't heard part one yet. It's probably the episode right before this Near Podcast player the episode you're about to listen to was sponsored by touched by type 1. Go check them out right now on Facebook, Instagram and of course@touchedbytype1.org check out that programs tab when you get to the website to see all the great things that they're doing for people living with type 1 diabetes. Touched by type1.org if you're looking for community around type 1 diabetes, check out the Juice Box Podcast. Private Facebook Group juice box podcast type 1 diabetes but everybody is welcome. Type 1 type 2 gestational loved ones it doesn't matter to me if you're impacted by diabetes and you're looking for support, comfort or community, check out Juice Box podcast type 1 diabetes on Facebook. Nothing you hear on the Juicebox Podcast should be considered advice, medical or otherwise. Always consult a physician before making any changes to your healthcare plan. The episode you're about to listen to is sponsored by TandemMobi. The impressively small insulin pump Tandem Mobi features Tandem's newest algorithm, Control IQ technology. It's designed for greater discretion, more freedom and improved time and range. Learn more and get started today@tandem diabetes.com Juicebox Today's episode is also sponsored by the Eversense 365. The Eversense 365 has exceptional accuracy over one year and is the most accurate CGM in the low range that you can get. Eversensecgm.com Juicebox and do you see less significant spikes around food?
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Yes. Like here's a really good example. I currently have an addiction to Sprite which is terrible. I have not like since my diagnosis. I probably had like two regular soda pops in that entire or like sodas in that entire seven years. When I started Mounjaro I like had some belly upset and like all I wanted was Sprite and I was able to dose for it and not go into the three 50s which that's never happened to me in my life. And it, it's like something is totally different. Like I can manage this with insulin and it's not going to put me over the edge, which to me is like, mind blowing.
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Do you know, I just was actually working on something this morning before you and I jumped on. And I didn't realize we'd be talking about this, but I'm pulling together a list of current trials or ideas for trials that are going on right now for GLP, beyond weight and type 2 diabetes and pre diabetes. It's also being looked at for cardiovascular disease, heart failure with preserved EF, chronic kidney disease, peripheral artery disease, general CV risk, reduction in obesity, obstructive sleep apnea, MASH NASH. I don't even know what this means. MASH NASH and NAFLD Essence Phase 3 and other programs, Alcohol associated liver disease, Alzheimer's disease, Parkinson's, alcohol use disorder, knee osteoarthritis with obesity, polycystic ovary syndrome, acute ischemic stroke. They are looking into it for. Let's see, what else? Anemia. Let's see. There are no anemia treatments right now. In a large cohort, inhibitors were associated with lower incidence of anemia with glps. Dermatology? Not definitive, but they're starting to talk about it as possible eczema treatment. There's strong evidence for joint pain, osteoarthritis, and there are active trials right now about long Covid recovery. Yeah, like, so it takes people like you who sit around and think, what else do I. Like, what do I not know right now? What should I be looking into? And what things are, you know, maybe sound crazy, but aren't. Aren't maybe not worth a shot. I'm not particularly ready to talk about this yet. I went to my wife two weeks ago. She was what I will call seven weeks deep into a long Covid flare. She was melting. Like, I don't know how she was alive, even. And I said, kelly, listen. I said, there's some people online, and I shudder to tell you this because I. I think first glance, these are not people who I'd listen to and go, all right, let's try it. I was like, but this thing that they're talking about, it's very low impact. It takes a month to figure out if it's going to work. Why don't you try a 7 milligram nicotine patch daily and see if it will help with your long Covid. There are people saying that it's helping with long Covid. And I said, I don't have all the details, but something about the spike proteins and how they grab onto the nicotine receptors, blah, blah, blah, like, I don't know. I'm just telling you, like, that's it. My wife looks at me. She's like, you're an idiot. Blah, blah, blah. And I was like, all right, fine. Like, whatever. Maybe a week later, I'm interviewing somebody, and she says, I have long Covid but it's getting a lot better. I said, oh, no kidding. What are you doing for it? She said, oh, I've been wearing nicotine patches.
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Wow.
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So I went back downstairs and I said to Kelly, I'm like, listen, it is not going to hurt you to wear a nicotine patch every day for 30 days. Like, it just isn't. And I ordered them and they're coming. And here, slap this on. And it's been two weeks, and you should see how much better she is.
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Wow.
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Really kind of crazy, right? And so then I dug around in it a little more, and, you know, there are peop. Again, this is. This isn't studied. This isn't. I'm not telling you. I mean, there are studies about nicotine, and you can go find them for yourself, but, like. But this isn't widely studied. There's no doctor running around telling you to try a nicotine. I'm not telling you to try it. Like, right. But there are people who say that they use it locally on joints to alleviate, like, RA symptoms and blah, blah. And I'm like, this is like. I don't know if that's true or not. I want to be completely clear. But that's what you need. You need people to say, like, here's the whole toolbox. I wonder what this would do. And not just randomly. I don't want you hitting a nail.
Episode #1718: Knowing All Your Tools – Part 2
December 24, 2025
Host: Scott Benner
Guest: Sarah
This episode continues the "Knowing All Your Tools" conversation, focusing on practical, real-world strategies for living well with Type 1 diabetes. Scott and Sarah delve into experimenting boldly and thoughtfully with treatments—both mainstream and unconventional—for diabetes management and related health challenges. The tone is open-minded, curious, and supportive, encouraging listeners to explore beyond the conventional with critical thinking and self-advocacy.
Sarah describes how her use of Mounjaro (a GLP-1 agonist) transformed her ability to bolus for sugar-laden foods, specifically Sprite.
Prior to Mounjaro, drinking regular soda would result in extremely high blood sugars ("the 350s"). With Mounjaro, she can dose insulin successfully without dramatic spikes.
Quote:
"When I started Mounjaro... all I wanted was Sprite and I was able to dose for it and not go into the 350s—which that's never happened to me in my life. And... something is totally different. Like I can manage this with insulin and it's not going to put me over the edge, which to me is like, mind blowing."
— Sarah [02:18]
Scott details the broad array of GLP-1 trials happening beyond diabetes and weight loss: heart failure, chronic kidney disease, cardiovascular risks, sleep apnea, liver diseases (MASH/NASH, NAFLD), Alzheimer's, Parkinson's, PCOS, knee osteoarthritis, anemia, dermatology (potential for eczema), and even long Covid recovery.
Quote:
"They're looking into it for... anemia... dermatology—it's starting to talk about it as a possible eczema treatment... There's strong evidence for joint pain, osteoarthritis... and there are active trials right now about long Covid recovery."
— Scott [03:03-03:54]
Scott emphasizes the importance of always exploring the full range of available tools, even if some ideas sound "crazy" at first.
Scott shares an anecdote about suggesting nicotine patches to his wife, Kelly, during a severe, weeks-long flare of long Covid, motivated by online testimonials—even though the research is preliminary.
Initially met with skepticism, Kelly later tried the patches after Scott interviewed a guest who had similar recovery success. Kelly's condition significantly improved over two weeks.
Quote:
"I said, Kelly, listen... Why don't you try a 7 milligram nicotine patch daily and see if it will help with your long Covid?... My wife looks at me. She's like, you're an idiot. Blah, blah, blah... Maybe a week later, I'm interviewing somebody, and she says, 'I have long Covid, but it's getting a lot better.' I said, 'Oh, no kidding. What are you doing for it?' She said, 'Oh, I've been wearing nicotine patches.'"
— Scott [03:57–05:47]
Quote:
"And it's been two weeks, and you should see how much better she is."
— Scott [05:48–06:06]
Scott underlines the importance of curiosity and safe trial:
Quote:
"That's what you need. You need people to say, 'Here's the whole toolbox. I wonder what this would do.' Not just randomly. I don't want you hitting a nail..."
— Scott [06:07–06:26]
Sarah on dosing success with Sprite and Mounjaro:
"I can manage this with insulin and it's not going to put me over the edge, which to me is like, mind blowing." [02:35]
Scott on GLP-1 trial diversity:
"...they are looking into it for... anemia... for eczema treatment, joint pain, osteoarthritis... and there are active trials right now about long Covid recovery." [03:45]
Scott’s anecdote about nicotine patches and Kelly’s long Covid:
"I said, 'Kelly, listen...just try a 7 milligram nicotine patch daily and see if it will help with your long Covid.'...It's been two weeks, and you should see how much better she is." [04:00–06:06]
On the value of curiosity:
"That's what you need...people to say, 'here's the whole toolbox'...Not just randomly." [06:07]
The episode is conversational, candid, and deeply practical—urging listeners to remain fearless, resourceful, and scientifically curious in their approach to diabetes and related health challenges. Both Scott and Sarah stress the need to be “bold with insulin” and to keep an open mind, while always remaining grounded and consulting vetted medical advice before trying new interventions.