
Hosted by Lex Fridman · EN

Michael Saylor is the CEO of MicroStrategy and a prominent holder and proponent of Bitcoin. Please support this podcast by checking out our sponsors: – Scale: https://scale.com/lex – Coinbase: https://coinbase.com/lex to get $10 in free Bitcoin – Audible: https://audible.com/lex to get $9.95 a month for 6 months – NetSuite: http://netsuite.com/lex to get free product tour – SimpliSafe: https://simplisafe.com/lex and use code LEX EPISODE LINKS: Michael’s Twitter: https://twitter.com/saylor MicroStrategy: https://microstrategy.com/ Michael’s Book: https://amzn.to/37J2iA0 Book mentioned: https://amzn.to/3jwsIaP PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:09) – Grading our understanding (19:27) – Inflation (39:03) – Government (1:00:13) – War and power (1:11:23) – Dematerializing information (1:42:45) – Digital energy and assets (1:54:23) – Oil barrel vs Bitcoin (2:03:43) – Layers of Bitcoin (2:20:53) – Bitcoin’s role during wartime (2:25:37) – Jack Dorsey (2:41:58) – Bitcoin conflict of interest (2:48:39) – Satoshi Nakamoto (2:54:04) – Volatility (3:06:30) – Bitcoin price (3:18:46) – Twitter verification (3:27:42) – Second best crypto (3:33:24) – Dogecoin (3:37:57) – Elon Musk (3:43:26) – Advice for young people (3:54:54) – Mortality (3:57:59) – Meaning of life

Karl Deisseroth is a professor of bioengineering, psychiatry, and behavioral sciences at Stanford University. Please support this podcast by checking out our sponsors: – BiOptimizers: http://www.magbreakthrough.com/lex to get 10% off – BetterHelp: https://betterhelp.com/lex to get 10% off – Notion: https://notion.com/startups to get up to $1000 off team plan – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off EPISODE LINKS: Karl’s Twitter: https://twitter.com/karldeisseroth Karl’s Website: https://web.stanford.edu/group/dlab Projections (book): https://amzn.to/3NKmdiJ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:58) – Mental disorders (15:31) – Intelligence (18:10) – James Joyce (26:47) – Writing (30:11) – Projections (33:46) – Translation (36:17) – Poetry (45:00) – Love (50:34) – Psychiatry (53:46) – Sigmund Freud and Carl Jung (1:02:30) – Data in cells (1:06:33) – Optogenetics (1:22:01) – Neuralink (1:34:49) – Psychedelics (1:41:13) – Depression (1:56:38) – Talk therapy and psychoanalysis (2:00:19) – Good Will Hunting (2:10:55) – Darkest moments (2:12:26) – Suicide (2:29:31) – Autism (2:49:09) – Schizophrenia (3:00:18) – Why we cry (3:07:30) – Consciousness (3:22:01) – Mortality (3:23:41) – Meaning of life

Yann LeCun is the Chief AI Scientist at Meta, professor at NYU, Turing Award winner, and one of the seminal researchers in the history of machine learning. Please support this podcast by checking out our sponsors: – Public Goods: https://publicgoods.com/lex and use code LEX to get $15 off – Indeed: https://indeed.com/lex to get $75 credit – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – NetSuite: http://netsuite.com/lex to get free product tour – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off EPISODE LINKS: Yann’s Twitter: https://twitter.com/ylecun Yann’s Facebook: https://www.facebook.com/yann.lecun Yann’s Website: http://yann.lecun.com/ Books and resources mentioned: Self-supervised learning (article): https://bit.ly/3Aau1DQ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:58) – Self-supervised learning (17:17) – Vision vs language (23:08) – Statistics (28:55) – Three challenges of machine learning (34:45) – Chess (42:47) – Animals and intelligence (52:31) – Data augmentation (1:13:51) – Multimodal learning (1:25:40) – Consciousness (1:30:25) – Intrinsic vs learned ideas (1:34:37) – Fear of death (1:42:29) – Artificial Intelligence (1:56:18) – Facebook AI Research (2:12:56) – NeurIPS (2:29:08) – Complexity (2:37:33) – Music (2:42:28) – Advice for young people

Michael Malice is a political thinker, podcaster, author, and anarchist. Please support this podcast by checking out our sponsors: – FightCamp: https://joinfightcamp.com/lex to get free shipping – Linode: https://linode.com/lex to get $100 free credit – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off – Sunbasket: https://sunbasket.com/lex and use code LEX to get $35 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Michael’s Twitter: https://twitter.com/michaelmalice Michael’s Community: https://malice.locals.com/ Michael’s YouTube: https://www.youtube.com/channel/UC5tj5QCpJKIl-KIa4Gib5Xw Michael’s Website: http://michaelmalice.com/about/ Your Welcome podcast: https://bit.ly/30q8oz1 Books & resources mentioned: The Anarchist Handbook (book): https://amzn.to/3yUb2f0 The New Right (book): https://amzn.to/34gxLo3 Dear Reader (book): https://amzn.to/2HPPlHS The Idiot (book): https://amzn.to/3zdHdHH Six-Word Memoirs (book): https://amzn.to/3zg51uv PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (09:07) – Truth, goodness, and beauty (19:35) – Save one life (26:26) – Jeffrey Epstein (45:21) – Jeffrey Epstein and Bill Clinton (51:33) – Christmas and New Years for Russians (58:14) – Russian cynicism and suffering (1:05:52) – Gift exchange (1:18:48) – Michael’s move to Austin (1:24:14) – The Anarchist Handbook (1:30:46) – Ghislaine Maxwell (1:35:20) – Jeffrey Epstein (1:37:34) – Lex’s move to Austin (1:46:21) – Elon Musk (1:49:31) – Writing The White Pill (1:54:18) – Camus (1:59:16) – Writing The White Pill continued (2:04:34) – New Year’s resolutions (2:18:09) – 2024 elections (2:30:38) – National divorce (2:45:15) – Joe Rogan and Bret Weinstein vs Sam Harris (2:54:26) – Conversation with CEO of Pfizer (3:07:59) – Anthony Fauci (3:13:28) – Advice for young people (3:23:30) – Wife and kids (3:28:57) – Immortality

Sean Kelly is a philosopher at Harvard specializing in existentialism and the philosophy of mind. Please support this podcast by checking out our sponsors: – Coinbase: https://coinbase.com/lex to get $5 in free Bitcoin – InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off – NetSuite: http://netsuite.com/lex to get free product tour – Ladder: https://ladderlife.com/lex – Sunbasket: https://sunbasket.com/lex and use code LEX to get $35 off EPISODE LINKS: Sean’s Twitter: https://twitter.com/sean_d_kelly Sean’s Website: https://scholar.harvard.edu/sdkelly Sean’s Wiki: https://en.wikipedia.org/wiki/Sean_Dorrance_Kelly PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:50) – Existentialism (26:58) – Nietzsche and nihilism (44:35) – Dostoevsky (1:00:02) – Camus and suicide (1:18:31) – The Big Lebowski (1:26:20) – Ayn Rand (1:36:28) – Evil (1:47:03) – Heidegger (1:58:43) – Hubert Dreyfus (2:04:35) – Moby Dick (2:15:51) – David Foster Wallace (2:36:03) – Can AI make art? (2:55:46) – Meaning of life

Michael Malice is a political thinker, podcaster, and author. Please support this podcast by checking out our sponsors: – Gala Games: https://gala.games/lex – Indeed: https://indeed.com/lex to get $75 credit – BetterHelp: https://betterhelp.com/lex to get 10% off – MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Michael’s Twitter: https://twitter.com/michaelmalice Michael’s Community: https://malice.locals.com/ Michael’s YouTube: https://www.youtube.com/channel/UC5tj5QCpJKIl-KIa4Gib5Xw Michael’s Website: http://michaelmalice.com/about/ Your Welcome podcast: https://bit.ly/30q8oz1 The Anarchist Handbook (book): https://amzn.to/3yUb2f0 The New Right (book): https://amzn.to/34gxLo3 Dear Reader (book): https://amzn.to/2HPPlHS Podcast (Round 1): https://www.youtube.com/watch?v=BIk1zUy8ehU PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:00) – Animal Farm (11:02) – Emma Goldman (14:07) – Albert Camus (15:37) – How to be a hero in Nazi Germany (22:43) – Camus on Existentialism vs Nihilism (28:44) – Cynicism is a lie (33:52) – Nazi invasion of the Soviet Union (54:10) – Lex and Michael argue: can most people think on their own? (1:05:48) – How Lex and Michael use Twitter (1:15:11) – Life is beautiful (1:18:13) – Returning to Ukraine (1:20:07) – Michael is now an underwear model (1:24:13) – The Anarchist Handbook (1:25:59) – Tolstoy was an anarchist (1:38:41) – Anarchy debate between Lex and Michael (2:07:49) – Why Michael doesn’t vote (2:25:04) – Austin and New York (2:33:40) – Alex Jones

David Sinclair is a geneticist at Harvard and author of Lifespan. Please support this podcast by checking out our sponsors: – Onnit: https://lexfridman.com/onnit to get up to 10% off – Clear: https://clearme.com/lexpod and use code LexPod to get 2 months free – National Instruments (NI): https://www.ni.com/perspectives – SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera – Linode: https://linode.com/lex to get $100 free credit EPISODE LINKS: David’s Twitter: https://twitter.com/davidasinclair David’s Website: https://lifespanbook.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (09:34) – Staying young at heart (13:31) – Bringing people back to life (19:05) – Wearables and tracking health data (28:18) – How to solve aging (38:23) – Why do we age? (43:50) – Genetic reset switch that reverses aging (46:20) – AI in biology (48:52) – Health data (56:58) – Fasting (1:04:29) – Diet (1:12:41) – Exercise (1:18:01) – Sleep (1:26:29) – Data (1:32:00) – Extending lifespan (1:34:42) – Immortality (1:40:28) – Denial of death (1:43:45) – Meaning of life without death

Vitalik Buterin is the co-founder of Ethereum. Please support this podcast by checking out our sponsors: – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off – Indeed: https://indeed.com/lex to get $75 credit – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Vitalik’s Twitter: https://twitter.com/VitalikButerin Vitalik’s Blog: https://vitalik.ca/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:18) – Shiba Inu story (25:35) – Regulation (29:48) – Crime (34:54) – Proof of stake vs proof of work (47:43) – Miner extractable value (53:19) – Scaling (54:42) – Bitcoin blocksize wars (1:00:51) – Hard fork vs soft fork (1:04:34) – Craig Wright (1:11:18) – Scaling: Sharding (1:18:07) – Scaling: Rollups (1:26:30) – Polygon and other Layer 2 technologies (1:34:11) – Merging PoS and PoW chains (1:43:49) – Lessons learned from Ethereum 2.0 failure incidents (1:52:35) – Bitcoin vs Ethereum (1:58:30) – Dogecoin (2:04:38) – Elon Musk (2:07:15) – Chainlink (2:10:35) – Charles Hoskinson and Cardano (2:18:08) – AI safety (2:23:07) – NFTs (2:25:57) – Scams (2:35:34) – Longevity (2:44:55) – Does death give meaning to life? (2:50:38) – Lex and Vitalik speak Russian (2:54:29) – Meaning of life (2:59:48) – Dan Carlin’s Hardcore History and WWII

Bryan Johnson is the founder and CEO of Kernel, OS Fund, and previously Braintree. Please support this podcast by checking out our sponsors: – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – NetSuite: http://netsuite.com/lex to get free product tour – Grammarly: https://grammarly.com/lex to get 20% off premium – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Bryan’s Twitter: https://twitter.com/bryan_johnson Bryan’s Website: https://www.bryanjohnson.co/ Kernel’s Twitter: https://twitter.com/KernelCo Kernel’s Website: https://www.kernel.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:57) – Kernel Flow demo (16:10) – The future of brain-computer interfaces (49:39) – Existential risk (55:18) – Overcoming depression (1:10:36) – Zeroth principles thinking (1:18:50) – Engineering consciousness (1:25:03) – Privacy (1:29:33) – Neuralink (1:39:11) – Braintree and Venmo (1:54:54) – Eating one meal a day (2:01:07) – Sleep (2:20:49) – Climbing Mount Kilimanjaro (2:27:47) – Advice for young people (2:32:23) – Meaning of life

Anthony Pompliano is an entrepreneur, investor, writer, and podcaster on topics of decentralized finance. Please support this podcast by checking out our sponsors: – Theragun: https://theragun.com/lex to get 30 day trial – Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Indeed: https://indeed.com/fridman to get $75 credit EPISODE LINKS: Anthony’s Twitter: https://twitter.com/APompliano Anthony’s YouTube: https://www.youtube.com/c/AnthonyPompliano Anthony’s Website: https://anthonypompliano.com/ Pomp Letter: https://pomp.substack.com/ Pomp Podcast: https://anthonypompliano.com/podcast/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:54) – Army (16:35) – Iraq (24:14) – Will there always be war? (31:27) – Bitcoin maximalism (39:56) – Money is a belief system (42:27) – Bitcoin (46:03) – Censorship (50:35) – Bitcoin as main currency (59:27) – Scarcity creates value (1:01:08) – Money is time (1:09:34) – Eric Weinstein vs Bitcoin Community (1:23:23) – Ray Dalio (1:40:31) – Bitclout (1:43:43) – How to get Bitcoin (1:54:28) – Investing (2:05:05) – Volatility (2:18:08) – Philosophy of the meme (2:28:03) – Dogecoin (2:37:33) – NFTs (2:43:21) – Virtual reality (2:48:17) – AI (2:54:18) – Bitcoin resources (2:58:44) – Book recommendations (3:01:22) – Can money buy happiness? (3:03:16) – Meaning of life