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Anecdotal stories suggesting that weight-loss drugs can help people shake long-standing addictions have been spreading fast in the past few years, through online forums, weight-loss clinics and news headlines. And now, clinical data are starting to back them up.Over a dozen randomized clinical studies testing whether GLP-1 drugs like Ozempic can suppress addiction are now under way, and neuroscientists are working out how these weight-loss drugs act on brain regions that control craving, reward and motivation.Scientists warn that the research is still in its early stages, but some researchers and physicians are excited, as no truly new class of addiction medicine has won approval from regulators in decades.This is an audio version of our Feature: Will blockbuster obesity drugs revolutionize addiction treatment? Hosted on Acast. See acast.com/privacy for more information.

Marc Abrahams created the Ig Nobel prizes in 1991, after years of collecting examples of weird research that he included in the Journal of Irreproducible Results. The aim of these satirical awards is to honour achievements that “make people laugh, then think”.While the initial response from the scientific community was mixed, last year the prize received more than 9,000 nominations. Several researchers who have won an ‘Ig’ say that it has improved their careers by helping them to reach wider audiences, and spend more time engaging with the public about their work.This is an audio version of our Feature: How a silly science prize changed my career Hosted on Acast. See acast.com/privacy for more information.

Many people around the world feel lonely. Chronic loneliness is known to have far-reaching health effects and has been linked to multiple conditions and even early death. But the mechanisms through which feeling alone can lead to poor health is a puzzle. Now, researchers are looking at neurons in the hopes that they may help explain why health issues arise when social needs go unmet.This is an audio version of our Feature Why loneliness is bad for your health Hosted on Acast. See acast.com/privacy for more information.

A new generation of anti-obesity medications are displaying striking results: drastically diminishing weight, without the serious side effects of previous medications.These drugs have raised hopes the weight can be pharmacologically altered in a safe way, but some researchers are concerned about the drugs' high cost, and that these medications could feed into some societies' obsessions with thinness.This is an audio version of our Feature: The ‘breakthrough’ obesity drugs that have stunned researchers Hosted on Acast. See acast.com/privacy for more information.

At the beginning of the COVID-19 pandemic, many countries introduced strict lockdowns to help prevent spread of the disease. Since then, researchers have been studying the effects of these measures to help inform responses to future crises.Conclusions suggest that countries that acted swiftly to bring in strict measures did best at preserving lives and their economies, but analysing the competing costs and benefits of lockdowns has been tough, as this work often comes down not to scientific calculations, but value judgements.This is an audio version of our Feature: What scientists have learnt from COVID lockdowns Hosted on Acast. See acast.com/privacy for more information.

A host of private companies are promising commercial fusion reactors in the next decade.After decades of promise, it finally seems that nuclear fusion is approaching commercial viability. Companies around the world are securing huge amounts of funding, and advances in materials research and computing are enabling technologies other than the standard designs to be pursued.This is an audio version of our feature: The chase for fusion energy Hosted on Acast. See acast.com/privacy for more information.

Lake Kivu, nestled between the Democratic Republic of the Congo and Rwanda, is a geological anomaly that holds 300 cubic kilometres of dissolved carbon dioxide and 60 cubic kilometres of methane.The lake has the potential to explosively release these gases, which could fill the surrounding valley, potentially killing millions of people.Researchers are trying to establish the likelihood of such an event happening, and the best way to safely siphon the gases from the lake.This is an audio version of our feature: How dangerous is Africa’s explosive Lake Kivu? Hosted on Acast. See acast.com/privacy for more information.

As women’s soccer, rugby and other sports gain in popularity a growing body of evidence suggests that female athletes are at a greater risk of traumatic brain injury than men - what's more they tend to fare worse after a concussion and take longer to recover. Now researchers are racing to get to the bottom of why and ask how treatment might need to change.This is an audio version of our feature: Why sports concussions are worse for women Hosted on Acast. See acast.com/privacy for more information.

A deluge of trials has stress-tested the systems that produce evidence.Around the world, researchers have raced to test therapies to treat COVID-19. The speed and urgency of this task has revealed both the weaknesses in the collection and use of research-based evidence, and how well-run trials have helped save lives.This is an audio version of our feature: How COVID broke the evidence pipeline Hosted on Acast. See acast.com/privacy for more information.

Scientists are trying to figure out whether these pervasive plastic specks are dangerous.Wherever they look – from the bottom of oceans to the top of mountains – researchers are uncovering tiny specks of plastic, known as microplastics.Scientists are trying to understand the potential impacts of ingesting these pervasive plastics but early results are ambiguous, as some experiments might not reflect the diversity of microplastics that exist in the real world.This is an audio version of our feature: Microplastics are everywhere — but are they harmful? Hosted on Acast. See acast.com/privacy for more information.