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Chris Brigham
Foreign.
Ed Gaudet
Welcome to Risk Never Sleeps where we meet and get to know the people delivering patient care and protecting patient safety. I'm your host, Ed Gaudet.
Saul Marquez
Hello everyone. Welcome back to the aimed 25 insight series. I'm Saul Marquez, here with my co host Ed Gaudette. Hey Saul, how you doing?
Ed Gaudette
I'm hanging in there. It's been a lot of fun around the corner.
Saul Marquez
Yeah, it's been such great conversations with just great thinkers, great doers in the business of AI and healthcare. And here with us today we have Chris Brigham. He's the founder of SmartMed HX AI. Such a pleasure to have you on the podcast with us, Chris.
Chris Brigham
So it's great to be with you. With you Ed, is an amazing event.
Ed Gaudette
Yeah. Really, truly has. And I hear you're going to be in the shark tank tomorrow.
Chris Brigham
Yes, I hope to swim and not get bitten.
Ed Gaudette
Yeah, because that won't end well, will it?
Chris Brigham
Be a bloody mess.
Ed Gaudette
But you'll have plenty of doctors around to help you.
Chris Brigham
This is true. This is true. You'll first consult chat GPT.
Saul Marquez
Survival.
Ed Gaudette
Man in water with a shark. What do we do? Pray this comes the answer, Chris.
Saul Marquez
So what are you enjoying about the meeting thus far and what brings you here?
Chris Brigham
What I enjoy about the meeting is sharing innovative concepts that improve healthcare, improve efficiencies and to meet with other like minded people.
Ed Gaudette
There's a lot of like minded people around here, that's for sure.
Chris Brigham
Yeah.
Ed Gaudette
How did you get into healthcare?
Chris Brigham
Well, a convoluted route. My background is it. Back in the 1960s, I was president of the first high school computer club in the us as far as we know, you're the guy. Vacuum tube computers, machine language.
Ed Gaudette
He's a ground zero for that.
Chris Brigham
Seriously. And then I had the good fortune to leave a lot of my high school in classes and do courses at Princeton in computer science.
Ed Gaudette
A Jersey Boy.
Chris Brigham
A Jersey boy. So I missed US History and social graces and other things. But I became assistance programmer for dow Jones at 17. Then a teaching assistant at the medical school Rutgers when I was 18. And then at the Laboratory Computer Science Master General when I was 21. So I was clearly a nerd.
Ed Gaudette
Fun at parties though.
Chris Brigham
Well, not. I would never be invited to parties. Come on.
Ed Gaudette
I would invite you to my party.
Saul Marquez
But you'd still show up though, Chris. Right.
Chris Brigham
But you weren't bored yet.
Ed Gaudette
Actually, I was.
You probably had the. You probably had the chemical compound for lsd, right? You're probably doing that in the basement. No, just kidding, Chris, back then is.
Chris Brigham
I was really intrigued by IT and how it could be applied to medicine. So I was planning to go down on an IT track, but instead I went to medical school. I went to Washington University School of Medicine, my MD there, and then boards initially in family practice, then preventive and occupational medicine. And my path has been how do we improve what we do in healthcare through innovative approaches and use of technology.
This has had different manifestations. I've written a few books and a few publications. About 300 and some odd.
Ed Gaudette
So Jama, you and Jama.
Chris Brigham
I was editor for a number of the AMA publications, so I had some involvement.
Ed Gaudette
Saul, where's the background on this guy? This guy's the real deal.
Saul Marquez
Seriously.
Chris Brigham
But I actually prefer not to talk about myself.
Ed Gaudette
And what, that's what you're here for?
Chris Brigham
Well, that's what I've been advised. So anyways, one of the things I've noticed over the years is that what's fundamental to understanding a patient is their history, their story. And we've lost the ability to listen because we don't have the time. We have an average of 16 minutes with a patient and we tend to interrupt patients within 11 seconds. Although Anthony Chang corrected me yesterday, he said it was seven seconds.
Ed Gaudette
That's a true stat. Really?
Chris Brigham
Yeah, that's a true stat, which is seven seconds. Yeah, we just don't have time. So we have systems like Avian Scribes, which are getting a lot of popularity and response. From my perspective, they're not as effective as it could be because they're passive. They're listening to a conversation is why not have a process of doing AI driving that? So my first involvement in AI was in the early 70s and with patient communication systems more rule based and now half a century later, because it took me some time in the past three years, is to develop an AI based system where a patient in advance of a visit would have a conversation with a caring, thorough, detailed historian interviewer who's AI. And in voice or text, in any language, effectively, which gives access to groups that otherwise have problems entering the healthcare system and gives global opportunities. So the history could take an hour. That information is then reviewed with the patient by the AI. So it's say so I understand you are concerned about this. Let me review this with you. And is this correct? Anything you have to or you want to modify with it and then takes that information, analyzes it, and then prepares a very detailed report for the physician. So at that point, then when I'm seeing the patient, I could say, oh, Saul, thanks for being so thorough with the history. Let me review some key points and some other questions. So we dramatically save the time. The physician doesn't have an hour in the additional hour to document that. We actually get that information beforehand. So it's an approach that I'm excited about. Is it in production or no, it's in reality.
Ed Gaudette
No. Is it in production? Is it being used with.
Chris Brigham
It's being used. It's just launched.
Ed Gaudette
Oh, awesome.
Chris Brigham
And it's starting small.
Ed Gaudette
Yeah.
Chris Brigham
But the response has been very positive by both the users who say that they're getting information that they otherwise would not get. And it's incredible. Timesaver. Yeah. So if we improve quality of information that gives a better understanding of the patient and we give an opportunity to really listen to patients and have them tell their stories.
Ed Gaudette
So we've been replaced and we don't even know it.
Chris Brigham
Well, you're not. No, no, you're not replaced ed, because what you could do.
Ed Gaudette
No ED has been placed and we don't even know it. That's a big.
Chris Brigham
So your AI is going to be.
Ed Gaudette
Caring, is going to ask questions. That sounds like what we do.
Chris Brigham
But let's say now. Doctor.
Ed Gaudette
All right, we're done. Chris, with you.
Chris Brigham
But you know what you can do now is instead of spending the time going over, getting all the information, you can now relate as a healthcare provider.
Ed Gaudette
We would know your background ahead of time.
Chris Brigham
You would know it be more effective. You can then give more feedback, more thought, less burnout, more efficiency. Tremendous.
Ed Gaudette
Interesting.
Chris Brigham
It's a different use case.
Ed Gaudette
I didn't heard about this.
Saul Marquez
Not just history from the EMR or the chart.
Chris Brigham
No, from the patient.
Ed Gaudette
It's key because everyone knows their story, right?
Chris Brigham
They should.
Ed Gaudette
They should. Yeah.
Saul Marquez
And then you leverage AI, right, to summarize everything for the doctor and maybe even listen to voice biomarkers that can tell you things.
Chris Brigham
Well, you can do biomarkers or what we do. And this is audio. So obviously we can't see what's here, but this is like a very detailed eight page history creating also a timeline.
Ed Gaudette
This all came out through the hours.
Chris Brigham
This is all through AI diagnoses, case summary, identifying key issues, giving some recommendations on what needs to be reviewed or what needs to be done next. And also insights to the historian. Is this somebody who was reliable or inconsistent or emotional?
Ed Gaudette
Did they lie about their smoking?
Chris Brigham
We don't know that. But we can start looking at inconsistencies. Yeah, right. And it's just gives. It's adaptive to the patient too. Because if you bring up an issue, it's not A structured questionnaire people don't like that it responds to. So you mention something, it will explore that.
Saul Marquez
Adaptive.
Chris Brigham
It's very adaptive. And it also adapts to the healthcare literacy of the individual. So if somebody's very sophisticated or simple.
Ed Gaudette
You gotta try this.
Chris Brigham
So this is. You know, what I want to give back to medicine. Yeah.
Ed Gaudette
I love it.
Chris Brigham
And I want this to go out globally because I want to provide care to those that are not able to access care. Yeah.
Saul Marquez
Just on the other side of the hotel at the Marriott is the Behavioral Health Tech Conference.
Ed Gaudette
Yes.
Saul Marquez
And I'm just thinking what a great application for behavioral health as well. Right?
Chris Brigham
Absolutely.
Saul Marquez
But if you could get the background of someone. Right. The story.
Seems like it'd be really useful.
Ed Gaudette
And that's like two therapy sessions in one. Yeah.
Saul Marquez
Can you bill for it?
Chris Brigham
The whole issue of billing is a different thing. We used to bill based on time.
Ed Gaudette
We don't care about billing, do we?
Chris Brigham
We should look at the value of what we're providing. But we could give feedback. Depends who you talk to. People.
Ed Gaudette
But he says he's giving it back.
Chris Brigham
No. Yeah. Well, I'm trying to give back. I've had experiences over a lifetime that maybe I can provide a legacy that.
Ed Gaudette
Yeah, that's great. That's more important than the money, is the legacy.
Saul Marquez
Yeah.
Ed Gaudette
We'll remember Chris Brigham.
Chris Brigham
Right.
Ed Gaudette
Before we forget Saul Marquez. For sure.
Chris Brigham
Totally. Right? Totally. And I may be the oldest person here at the conference.
Ed Gaudette
Yeah. I'm not going to say anything about it. I'm going to ask you a couple questions.
Chris Brigham
Sure.
Ed Gaudette
It'll be fun. So let's see, you're on a desert island, five records. Now, you're a child of the 60s, so these ought to be interesting.
Chris Brigham
Oh, I don't. Cat Stevens, Beatles.
Ed Gaudette
Nice. Yeah.
Chris Brigham
Peter, Paul, Mary.
Ed Gaudette
Oh, thank God. A human being who knows music.
Chris Brigham
Yeah.
Ed Gaudette
What else you got?
Chris Brigham
Two more. Oh, I don't know.
Ed Gaudette
What are you listening to now?
Saul Marquez
I was just gonna ask that James Taylor.
Ed Gaudette
Oh, nice. James Taylor's good. He wasn't a nice person, though, early in the.
Chris Brigham
I didn't. I didn't know that.
Ed Gaudette
Yeah. He was really Nora Jones. Oh, yeah.
Chris Brigham
Nora Jones. Smooth.
Ed Gaudette
Do you know who Nora Jones parents are?
Chris Brigham
Yes. And folk singer. Who's it se. Who was it?
Ed Gaudette
No, it's Robbie Shankar. Right. Oh, right.
Chris Brigham
It was Robbie Shankar.
Ed Gaudette
Who's the woman? Somebody we wouldn't really expect. Yeah. Yeah.
Chris Brigham
Shoot. Parents are very.
Ed Gaudette
They're celebrities. And Ravi Shankar's 60s, right?
Chris Brigham
Yeah, he's 60s now. Remember I was a nerd So I was working with the computers and not listening to the music all the time and at the parties that you were at. That's true.
Ed Gaudette
We need to get you out more, Chris.
Go back in time and see your 20 year old self. What would you tell him?
Chris Brigham
Live life fully. Yeah, live life fully. And my faith is also very important, so my relationship with the Lord. And you follow that, what's your religion? I'm a Presbyterian Christian.
Ed Gaudette
Okay, recent or something you found recently?
Chris Brigham
Well, it's varied in intensity and more of a focus now of my life. Nice.
Ed Gaudette
What makes it a focus?
Chris Brigham
Well, my whole purpose here is to glorify my Lord and to live a life that reflects that. And it's through the grace of Christ.
Ed Gaudette
You're a good person.
Chris Brigham
Well.
That'S debatable.
Ed Gaudette
And then he's got that smile that.
Saul Marquez
Like he's ready for the shark tank. He's ready for the shark tank.
Ed Gaudette
Okay, I have a couple more questions.
Saul Marquez
That's right.
Chris Brigham
Yes.
Saul Marquez
All right.
Chris Brigham
Make them easy.
Ed Gaudette
What's the risk? No, wait a minute. You have experience. You're the oldest guy here. You've lived a life full. Right. What's the riskiest thing you've ever done?
Chris Brigham
Probably the riskiest was sailing my sailboat from Maine down to Hilton Head.
Ed Gaudette
Oh.
Chris Brigham
And being offshore in conditions that I should not have been offshore in. Really? How big were the waves? Maybe like 15ft. Wow.
Ed Gaudette
During a storm or massive.
Chris Brigham
Just during bad judgment. Yeah.
Ed Gaudette
I've been in 15 foot waves and it's. What kind of sailboat?
Chris Brigham
It was a saber. 30 foot.
Ed Gaudette
Saber's beautiful. Yeah. This was an. Well, let's see, it was a main ship, 46, coming out of Newport, Rhode Island. And the waves were so big that coming back into the harbor was a sailboat with the mask snapped in half. And we just kept going. My father in law was the captain and all of a sudden the waves. And he said something like, oh. And that's what. I knew we were in trouble. But he took, he, he went into the trough and pivoted that thing on a dime and I don't know, we would have been dead. Well, that's great survival. Yeah, but have you been capsized?
Chris Brigham
I have not, no.
Ed Gaudette
Okay, so you may have to. No Saber though, was that like, what was your name?
Chris Brigham
The. That one was Apple Wine.
Ed Gaudette
Apple Wine.
Chris Brigham
And now I have a trawler. You do What? What do you have? A saber.
Ed Gaudette
A saber.
Saul Marquez
You're a saber guy.
Ed Gaudette
I'm trying to get him to get a pie of saber right now. What.
Chris Brigham
How big 36ft.
Ed Gaudette
Yeah. That's what I'm.
Saul Marquez
Okay.
Chris Brigham
Exactly.
Ed Gaudette
The bonus. It's like a sweet spot. There's too much TE's, like there's too much teak on this thing. I don't want to. Do you have a lot of teak or enough teak? Enough, yeah. It's beautiful. That's a beautiful boat. You like the Hinkley?
Chris Brigham
I love the Hinkley.
Saul Marquez
Yeah.
Chris Brigham
In fact, the I. When I practiced clinical medicine years ago, it was in Mount Desert island. So I got to know the Hinckleys. And then a friend of mine, Henry's son Hank, became my chief operating officer when he was tired of the marine industry. So Hank worked with me for about three years. He had, before that, ocean cruising yacht.
Ed Gaudette
There's the story right there. See how we take that right out? We bring that. So they had a Sparkman Stevens.
Chris Brigham
Beautiful 40.
Ed Gaudette
That was like a 42, 44.
Chris Brigham
I don't remember.
Ed Gaudette
It was beautiful. Custom made. Yeah. My claim to fame on that boat was I was dating their daughter at the time and we were sailing down the Bahamas, I think it was like Staniel Key. You ever been down there?
Chris Brigham
No.
Ed Gaudette
Bahamas.
Chris Brigham
Well, I've been to Bahamas, but not the place.
Ed Gaudette
And I dropped the winch handle and it left like a 6 inch divot in his teeth. And he wasn't too happy with that.
Chris Brigham
I could understand.
Ed Gaudette
Yeah, he was pretty upset. But I'm surprised he let me marry his daughter, quite frankly.
Chris Brigham
But that happens.
Ed Gaudette
It does happen.
Chris Brigham
Did you still have the wench handle or did it go overboard?
Ed Gaudette
I think it went overboard, actually. I think it was a double. A double whammy, I think. Yeah. I was like, what's the problem? Don't you have another one of these?
Chris Brigham
Oh, man.
Ed Gaudette
Wasn't good. Another terrifying thing. You ever have a quadrant break on a sailboat while you're coming into harbor?
Chris Brigham
I've never wanted that to happen. Yeah, it's not good.
Ed Gaudette
It's not good. It's like the worst thing that can happen because it's your steering.
Saul Marquez
Yeah. And you pretty much.
Ed Gaudette
You know what you do when that happens? When you're coming in hot into the.
Chris Brigham
Harbor, you say the same words that were said before. Oh, no, worse.
Ed Gaudette
And when it's only two of you, him and me, he's screaming to get the pole. Like, I know what the hell the pole is. Get the pole. Get the. We didn't manually steer ourselves in with this pole.
Chris Brigham
Right.
Ed Gaudette
Whatever the hell that pole thing is called.
Saul Marquez
I forget.
Ed Gaudette
But it went right to the rudder in the back.
Chris Brigham
Yes.
Ed Gaudette
That's the backup, whatever that was, man. I found a pole and that is the backup.
Chris Brigham
Yeah.
Ed Gaudette
Now, do you get crazy when you're sailing or boating?
Chris Brigham
What do you mean by crazy?
Ed Gaudette
He's like the nicest guy, but when he would be behind the wheel, whatever you want to call it, I'm kind of killing this.
He just became another person. So, like, if you're docking, you're bringing the boat in and stuff, like, if you're not precise with everything, he's like screaming at you.
Chris Brigham
Yeah. That's always the biggest challenge with the trawler. I have twin screws.
Ed Gaudette
Yeah.
Chris Brigham
And you have to do it entirely, you know, by that. Yeah. One going forward, one going reverse, turning around. And that's the high intensity time and.
Ed Gaudette
The wind and the tide and you got, you know, everything. Give a thruster to get into that.
Chris Brigham
No thrust. No thrust, no thrusters.
Saul Marquez
Thrusters help.
Chris Brigham
Thrusters help hard. Right.
Saul Marquez
So you get a little.
Ed Gaudette
You get a little excited, I bet.
Chris Brigham
Get a little excited. Right. Just get out my iPad and I go to ChatGPT and I don't.
Ed Gaudette
That's good.
Chris Brigham
That's good.
Saul Marquez
Listen, so if you wanted to share anything from the conference with our listeners that couldn't be here, what would you. What do you want to share with.
Chris Brigham
Them, Chris, is embrace AI. Recognize that there are challenges, but we need to innovate. We need to improve, we need to get better outcomes, we need to decrease costs. So just reinvent what we do in a way that's much more effective.
Ed Gaudette
I love that. Well, good luck in the shark tank.
Chris Brigham
Thank you.
Ed Gaudette
I think you're going to do gray well.
Chris Brigham
I'm looking forward to it.
Ed Gaudette
Yeah.
Saul Marquez
If people want to learn more about you and the work that you do, Chris, where can they reach out?
Chris Brigham
They can reach out to smartmedhx, AI or cbrigham.com that's awesome. All right, there you have it. Thank you so much. Thank you. Appreciate the show. And, Ed, it was a delight to be with you.
Saul Marquez
Pleasure to have you on.
Ed Gaudet
Thanks for listening to Risk Never Sleeps for the show. Notes, resources, and more information and how to transform the protection of patient safety. Visit us@SenseInet.com that's C-E N S I N E T dot com. I'm your host, Ed Gaudet. And until next time, stay vigilant because Risk never Sleeps.
Episode Title: The Path To Faster Medicines Starts With Better Trial Access
Guest: Chris Brigham, Founder of Smart Medical History AI
Host: Ed Gaudet (with guest co-host Saul Marquez)
Date: December 10, 2025
In this episode, Ed Gaudet and guest co-host Saul Marquez sit down with Chris Brigham, the founder of Smart Medical History AI (SmartMed HX AI), during the AIMED 25 conference. The conversation centers on how AI-driven patient history tools can transform medical trials and everyday healthcare by providing faster, more comprehensive, and more accessible clinical trial access and improved patient-provider interactions. Chris shares stories from his storied career in both IT and medicine, and the group explores the opportunities and challenges in digitally reinventing patient history taking.
Early Beginnings in Tech and Medicine
Accomplishments
Challenges with Current State
Limitations of Current AI Tools
Concept & Functionality
Benefits
Clinical Workflow Improvements
Adaptability and Reliability
Potential for Global and Behavioral Health Applications
Billing and Motivation
On Time Constraints:
On AI’s Impact:
On Providing Global and Inclusive Care:
On Motivation & Legacy:
On the Future of Healthcare AI:
Chris’s Musical Taste
Faith & Philosophy
Sailing Stories
Chris Brigham’s vision through Smart Medical History AI is bold and heartfelt: to use adaptive, inclusive AI to fill critical gaps in patient history-taking, fundamentally improving clinical care and trial access—while reclaiming time, focus, and relational depth for both patients and providers. As Ed and Saul note, it’s not just about technology: it’s about legacy, access, and honoring the patient story.
Contact for more info:
Memorable Closing Quote:
“Embrace AI. Recognize that there are challenges, but we need to innovate. We need to improve, we need to get better outcomes, we need to decrease costs. So just reinvent what we do in a way that's much more effective.”
— Chris Brigham, (17:51)