Risk Never Sleeps Podcast: Episode #214
Pharmacy Roulette: Why Your Prescription Price Makes No Sense
Guest: Miriam Paramore, Founder & CEO of RxUtility
Host: Ed Gaudet
Date: April 28, 2026
Overview
In this episode, Ed Gaudet sits down with Miriam Paramore, the founder and CEO of RxUtility, to untangle the confusing world of prescription drug pricing. Together, they explore why it’s so difficult for consumers to know what their out-of-pocket drug costs will be and discuss how technology—especially data aggregation and AI—can help make prescription drugs more affordable and accessible. The conversation weaves practical insights about pharmacy and insurance practices with personal anecdotes, while also touching on risk, entrepreneurship, and Miriam’s personal passions.
Key Discussion Points
1. The Mission of RxUtility: Bringing Affordability and Transparency (01:04–02:00)
- RxUtility’s Focus: Making medications more affordable for consumers at the pharmacy counter, targeting the “wallet moment.”
- Miriam’s Mission:
“Our focus and our mission is to save people money on medicine.” (01:04–01:14)
- Industry Challenges: Consumers don’t know the cost of their medications until they arrive at the pharmacy, due to the opaque nature of drug pricing systems.
2. Miriam’s Background and Path to RxUtility (01:54–05:16)
- Journey into Health Tech: Started as a computer science and math major, worked as a programmer for Hospital Corporation of America (HCA), and gained leadership experience over 40+ years in healthcare IT.
- Entrepreneurial Experience: Ran consulting and software businesses prior to founding RxUtility.
- On Bootstrapping:
“I am the founder and the CEO and funding the business… Bootstrap, correct.” (03:15–03:21)
- Mission-driven Motives: A for-profit business that’s also “mission-driven,” aiming to give back and address real consumer needs.
- On Taking Risks:
“I decided to really put my money where my mouth was and see if I could build something that really helps consumers.” (03:49–03:57)
3. How RxUtility Works: Data, AI & Integration (05:16–08:38)
- Data-as-a-Service: Collects, aggregates, and organizes vast sets of drug and pricing data for integration into existing healthcare workflows.
- Uses both OpenAI and Claude large language models, with a robust, curated data foundation.
- Integration Points:
RxUtility does not compete with EHRs or pharmacy management; rather, it’s a utility offering API-accessible pricing data that partners embed for consumer-facing transparency.
“We sit as a business to business utility tool where they can subscribe to our data and then bring our data to the surface through their workflows that people already use.” (07:10–08:38)
- Market Forces: Regulatory requirements and consumer pressure are pushing even reluctant stakeholders toward transparency.
4. Direct-to-Consumer Evolution & Manufacturer Price Offers (09:04–11:15)
- Disruptive Market Changes:
2025 was the first year major pharmaceutical manufacturers sold directly to consumers, notably for GLP-1 drugs.
- Resulting Price Compression: Increased transparency leads to real marketplace dynamics and lower prices.
- Copay Coupons:
“There are about $30 billion of consumer savings available every year for consumers to use when they pick up a branded drug...a copay coupon can bring the consumer's cost down to $0, $5.” (10:34–11:15)
5. The Realities & Pitfalls of Drug Switching (11:15–13:09)
- Ed’s Personal Story: Prescription for lisinopril was switched to a different manufacturer without clear communication, raising issues about potential side effects and consumer agency.
- Miriam on Pharmacy Switches:
“There are switching programs that happen that the consumers never know and it’s wrong.” (12:03–12:23)
- Clinical Impact: Sometimes generic substitutions or manufacturer switches can cause adverse effects despite being classified as the “same” by the pharmacy/hospital system.
6. How RxUtility Delivers Value for Consumers (14:01–15:14)
- Insurance vs. Cash: Many consumers don’t realize that paying cash can be cheaper than using insurance for some generic drugs.
- “If you paid cash for that exact same drug, $2.18. But no consumer would know that because you just assume if I use my insurance benefit.” (14:44–15:14)
- Empowering Choice: RxUtility displays all pricing options (insured/copay and cash prices) so the consumer can always find the best deal.
Memorable Quotes and Moments
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On the confusion at the pharmacy counter:
“There’s really no way for a consumer to know until they show up to the pharmacy and then they’re told.” (01:36–01:44)
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On building with AI:
“It's astonishing the capital efficiency that you can... experience as an entrepreneur with very few human resources and you can create agents, write code for you. And we do.” (06:15–06:32)
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On receiving new, different drugs at the pharmacy:
“They say, ‘Oh, it’s the same, it’s the same thing. It’s the same.’ It’s not the same thing.” (11:54–11:57)
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On drug pricing and insurance:
“You still have a copay on a tier one drug... If you paid cash for that exact same drug, $2.18. But no consumer would know that.” (14:40–14:45)
Rapid-Fire: About Miriam (15:14–18:52)
- Advice to her 20-year-old self:
“Don’t be so insecure.” (15:24)
- Riskiest thing ever done:
“This is the riskiest thing I’ve ever done. In dollars.” (15:35–15:37, referring to funding RxUtility herself)
- If she weren’t in health tech:
“Politics... I believe in equality.” (16:54–18:03)
She speaks passionately about women’s rights, equality, and her hope for positive change in America.
Notable Segments and Timestamps
| Segment Topic | Timestamp |
|-----------------------------------------|-------------|
| Company’s mission and “cheap drugs” | 01:04–01:14 |
| Miriam’s health tech background | 01:54–05:16 |
| Technology and AI in RxUtility | 05:16–08:38 |
| Direct-to-consumer drug sales | 09:04–11:15 |
| Ed’s drug switch experience | 11:15–13:09 |
| Insurance vs. cash revelations | 14:01–15:14 |
| Personal rapid-fire Q&A | 15:14–18:52 |
Episode Tone
- Conversational and candid, with Miriam bringing both technical depth and passionate advocacy.
- Ed’s relaxed style invites openness and storytelling, with humor and personal anecdotes that spotlight both the struggle and opportunity in pharmacy pricing.
Summary Takeaways
- U.S. drug pricing is deliberately opaque, but technology and consumer advocacy are pushing toward more transparency and affordability.
- RxUtility is building the data infrastructure to democratize drug-pricing information, enabling both consumers and healthcare players to surface and act on the best prices available.
- There’s still much work to be done—on price transparency, consumer education, and broader issues of equality both inside healthcare and within society at large.
Memorable Closing Quote:
“It’s a bad thing if someone had a negative reaction after it was switched, but they needed to go back to the brand, and then they couldn’t afford the brand because your health plan dropped it from the formulary and now you’re just out in the cold.”
—Miriam Paramore (13:34–14:01)
For more information or to listen to the full episode, visit Censinet.com.
Prepared for listeners seeking deep insight into prescription drug pricing, technology innovation in health tech, and the personal drives behind healthcare entrepreneurship.