The AI CEO Podcast is a show for CEOs, founders, and business leaders navigating the biggest technology shift of our lifetime. Each episode explores how artificial intelligence is reshaping leadership, business strategy, marketing, and growth—translating complex AI concepts into practical insights leaders can use to make smarter decisions and stay competitive.

AI is no longer optional—it's redefining how companies operate, compete, and lead. In this episode of The AI CEO Podcast, Talisha Padgett breaks down why successful AI adoption starts with people, process, and data, how leaders should view AI as a strategic partner, and what CEOs must do now to build resilient, human-centered organizations in an AI-driven world. In this episode, you'll learn:

-Why "people, process, and technology" must evolve together -How CEOs should think about AI strategy—not just tools -Real-world marketing and AI use cases that save time and money -Why data quality is the real competitive moat -How to keep humans in the loop while scaling with AI Timestamps:

00:00 – How CEOs should think about AI and change 01:15 – Podcast and guest introduction (Talisha Padgett, Microsoft) 03:00 – People, process, and technology in AI transformation 06:30 – Human Loop Consulting and change management 09:00 – Fear, jobs, and keeping humans in the loop 12:00 – Learning AI as a non-technical leader 18:00 – Why AI pilots fail and how to succeed 25:00 – Microsoft Copilot and practical AI adoption 33:00 – Personalization at scale and real-world examples 39:00 – AI's impact on marketing roles 46:00 – Privacy, regulation, and responsible AI 57:00 – Deepfakes, security, and data protection 59:00 – Unlocking value from existing business data 01:02:00 – AI strategy for startup CEOs 01:06:00 – Early-stage growth and positioning 01:10:00 – AI maturity, leadership responsibility, optimism 01:15:00 – Final reflections on AI, humans, and the future 01:19:00 – Closing thoughts and wrap-up

About Talisha Padgett

Talisha Padgett is the General Manager of Marketing Technology & AI at Microsoft and the Founder of Human Loop Consulting, where she operates at the intersection of marketing transformation, artificial intelligence, and human-centered change management. With over two decades of experience leading digital and marketing transformation across global brands—including Microsoft, Under Armour, Marriott International, and Comcast—Talisha brings a rare blend of enterprise-scale execution and strategic clarity. Her work focuses on helping organizations modernize marketing operations by aligning people, process, data, and technology to real business outcomes.

LinkedIn: https://www.linkedin.com/in/talishapadgett/

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About Seema Alexander

Seema Alexander is the Founder of Disruptive AI, Co-Chair of DC Startup & Tech Week, and host of The AI CEO Podcast. She guides CEOs, founders, and business leaders through AI adoption, organizational transformation, and the future of business. She is also an international keynote speaker on AI and business for global audiences.

Her upcoming AI CEO School and AI Business Conference will provide strategic education, tools, and frameworks for non-technical CEOs and founders navigating the AI era.

IG: https://www.instagram.com/seemaalexander/ LinkedIn: https://www.linkedin.com/in/seemaalexander/ Disruptive AI: www.getdisruptive.ai

Connect with The AI CEO Podcast

Instagram: https://www.instagram.com/theaiceopodcast/ LinkedIn: https://www.linkedin.com/company/the-ai-ceo-podcast/

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