Podcast Summary: The Dr. Josh Axe Show – "How to Fix Your Metabolism | Haylie Pomroy"

Introduction

In the January 16, 2025 episode of The Dr. Josh Axe Show, host Dr. Josh Axe welcomes Haylie Pomroy, a New York Times bestselling author and PhD candidate in neuroimmunology. The episode delves deep into understanding metabolism, its intricate connection with hormones, and actionable strategies to optimize metabolic health. Targeting individuals struggling with weight loss despite healthy eating and regular exercise, Pomroy shares her expertise on repairing and stoking metabolism through nutrient-dependent pathways and personalized dietary approaches.

Understanding Metabolism and Hormones

Pomroy emphasizes that metabolism and hormonal health are intrinsically linked. She explains, “[...] how we secrete our hormones, how we make them bioavailable, so the body can utilize them. How we bind with receptor sites are all metabolic processes” (04:20). Metabolic imbalances can lead to hormonal disorders such as hypothyroidism and Hashimoto's disease. According to Pomroy, addressing these imbalances requires not just medication but a comprehensive healing of metabolic pathways through proper nutrition and lifestyle adjustments.

The Fast Metabolism Diet: A 28-Day Rehab

Pomroy introduces her signature approach, the Fast Metabolism Diet, which spans 28 days and focuses on cycling nutrients to repair and optimize metabolic pathways. The diet is divided into specific phases:

1. Phase 1 (Days 1-2): High Complex Carbs

   • Emphasizes complex carbohydrates like mangoes, watermelon, brown rice, and sweet potatoes.
   • Aims to increase serotonin, dopamine, and other neurotransmitters by effectively metabolizing carbs.

2. Phase 2 (Days 3-4): High Lean Proteins and Alkaline Vegetables

   • Focuses on breaking down proteins into essential amino acids.
   • Balances protein intake with alkaline vegetables to support DNA synthesis and hormone production.

3. Phase 3 (Days 5-7): Lower Glycemic, High-Fiber Complex Carbs

   • Incorporates low glycemic, high-fiber fruits and healthy fats.
   • Supports liver detoxification and fat metabolism while ensuring metabolic pathways are not overstressed.

Pomroy asserts, “We rotate the diet through the week […] We want to reinoculate, we have to excite enzyme and hormone secretion, we have to wash hormone receptor sites and we have to reincorporate” (29:25). This cyclical approach prevents metabolic fatigue and promotes sustained weight loss and hormonal balance.

Nutrient Dependency and Common Deficiencies

A central theme is the reliance on nutrients to maintain and repair metabolic functions. Pomroy highlights several key nutrients often deficient in modern diets:

• Omega Fatty Acids (Omega-3 and Omega-6): Essential for anti-inflammatory processes and hormone production. Pomroy notes, “They are naturally the building blocks for their natural anti-inflammatory hormones” (60:15).

• B Vitamins: Crucial for methylation and energy production. However, Pomroy cautions that without a healthy gut microbiome, even adequate intake may not be effective.

• Vitamin C: Vital for immune function and hormone metabolism. She recommends sourcing non-corn-derived Vitamin C to avoid exacerbating conditions like mast cell activation (62:59).

• Probiotics: Essential for gut health, which in turn supports nutrient absorption and metabolic efficiency.

Pomroy underscores the importance of a high-quality multivitamin: “I really do believe in a high-quality multivitamin […] our food is deficient and devoid” (60:15).

Peptides and Weight Loss Drugs: A Cautionary Tale

Discussing contemporary weight loss solutions, Pomroy expresses concern over peptides like Ozempic and Wegovy. She states, “It breaks my heart because it's wrecking immune […] the metabolism is wrecking it” (40:20). While acknowledging the potential of peptides in certain medical contexts, she warns against their widespread use without addressing underlying metabolic health, arguing that such drugs may disrupt natural metabolic pathways and immune function.

Agriculture, Food Quality, and Environmental Toxins

Pomroy draws parallels between regenerative agriculture and human health, emphasizing that just as soil quality affects plant health, the food we consume directly impacts our metabolism. She criticizes the prevalence of processed foods laden with additives and preservatives, stating, “Food is not the enemy. It's the things that are allowed to be called food” (50:25). Pomroy advocates for whole, unprocessed foods and supports regenerative farming practices to ensure nutrient-rich produce.

Hormone Replacement Therapy (HRT): Proceed with Caution

Pomroy advises caution regarding HRT, especially for women experiencing hypothyroidism and menopause. She emphasizes natural hormone support before considering exogenous hormone therapies: “The first thing you should do is try and help your body make more estrogen, make more progesterone in the right levels yourself” (71:32). Pomroy warns that unnecessary HRT can disrupt the body's natural hormone production and lead to further metabolic imbalances.

Stress, Mindset, and Metabolic Health

Addressing the psychological aspects of metabolism, Pomroy highlights how stress and mindset significantly influence metabolic function. She explains, “If you have shame, if you're feeling shame and guilt, what that is doing to your cortisol, what that's doing to your adrenal hormones, what that is doing to your metabolism is tanking it” (38:22). Pomroy advocates for a holistic approach that includes stress reduction, emotional resilience, and spiritual growth to support metabolic health.

Practical Steps to Optimize Metabolism

1. Adopt a Rotational Diet: Follow structured dietary phases to keep metabolic pathways active and prevent fatigue.

2. Emphasize Whole Foods: Focus on nutrient-dense, unprocessed foods to provide the necessary building blocks for metabolic functions.

3. Supplement Wisely: Incorporate essential supplements like Omega fatty acids, B vitamins, Vitamin C, and probiotics to address common deficiencies.

4. Support Gut Health: Maintain a healthy microbiome through diet, probiotics, and mindful eating practices.

5. Manage Stress: Implement stress-reduction techniques such as meditation, exercise, and adequate sleep to support hormonal balance.

6. Avoid Over-reliance on Medications: Prioritize natural metabolic repair over quick-fix medications and consult knowledgeable healthcare practitioners for personalized guidance.

Notable Quotes

• “You cannot out medicate or even out supplement a bad metabolism.” (00:00)
• “There is no species in the world where diet means deprivation.” (01:00)
• “Shame and guilt have no place in getting well. Guilt and shame have no way to move the scale, period.” (38:34)

Conclusion

Haylie Pomroy provides a comprehensive guide to understanding and optimizing metabolism through nutrient-dependent pathways and personalized dietary strategies. By emphasizing whole foods, addressing common nutritional deficiencies, managing stress, and adopting a rotational diet approach, individuals can repair and enhance their metabolic health. Pomroy's insights challenge conventional weight loss methods, advocating for a holistic, sustainable approach grounded in science and regenerative principles.

For those seeking to transform their metabolic health and achieve sustainable weight loss, this episode offers invaluable strategies and a fresh perspective on the intricate dance between diet, hormones, and overall well-being.

About the Guest: Haylie Pomroy

Haylie Pomroy is a renowned health expert, New York Times bestselling author of "The Fast Metabolism Diet," and a PhD candidate in neuroimmunology. With over 30 years of experience, Pomroy has helped countless individuals achieve optimal metabolic and hormonal health through her evidence-based, personalized approaches.

Resources Mentioned

• BeyondBloodwork.com: For deeper insights into cellular health and metabolism.
• Fast Metabolism Diet Book: Available on Amazon and HayliePomroy.com with free shipping options.