Transcript
Peloton Announcer (0:00)
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Palmolive Announcer (0:56)
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Dr. Josh Axe (1:23)
Shop now@palmolive.com if you've tried thyroid medications, birth control, antidepressants, metformin, TRT or HRT, and you're still dealing with fatigue, weight gain, or brain fog. You don't have one hormone problem. You actually have what I call a hormone cascade problem. Today, I'll show you how hormones work like dominoes. When the upstream signal breaks, everything downstream fails. And I'll cover the biggest cascades behind issues like hypothyroidism, stress and insulin resistance, pcos, infertility, low testosterone, and menopause. And I'll walk you through exactly how to restore the signal at the source and heal your hormones at the root cause. Welcome to the Dr. Josh Axe Show. So I can't tell you how many patients I've seen over the years, and they've told me, Dr. Axe, I've tried thyroid medications. I've tried hormone creams, birth control, even insulin, but nothing is working for me. But when I zoomed out, I was able to realize something crucial. They were treating the symptoms, not the root problem, which is a hormone cascade. Issued. And once we fixed the upstream signal, the downstream hormones corrected themselves automatically. Now, most doctors today treat hormones like isolated light switches. One hormone is on or one is off, and they try to fix it in isolation. But hormones don't work independently. They work in sequences. They work synergistically together. Think of hormones like a domino chain or a waterfall. One signal triggers the next and the next and the next. And this happens over time. Now, I want to give you an example of how this happens, and I'm going to walk you through exactly how you can heal the root causes of, as I mentioned, pcos, low testosterone, insulin resistance, hypothyroidism, and menopause with this strategy. But an example of this would be with the endocrine cascade. You know, one of the things that happens so often when people eat foods that can imbalance blood sugar. And it could be not just sugar, processed carbohydrates, it could be even certain types of dairy. And what this will do is all of a sudden, your blood sugar is off. Okay, so we see blood sugar is off. And then what happens is insulin's impacted, right? So we see insulin. Well, when insulin increases, that increases stress on the adrenal glands. So then the adrenal glands start impacting your pituitary gland. And this is where you're releasing cortisol and stress horm. And then your thyroid is impacted. And then your sex hormones, like estrogen and testosterone, then those are impacted. And we see that there are different initial dominoes that will kick off hormone imbalance. And if the first domino falls the wrong way or the water source is disrupted upstream, everything downstream is then impacted. Even those glands themselves that are perfectly healthy, those are impacted. And that's why fixing one hormone number often doesn't fix how you feel, because the original signal never got restored. I can tell you from taking care of thousands and thousands of patients with hypothyroidism, even when they get on a T4 medication like levothyroxine, they still don't feel 100%. There's still metabolism issues, there's still thinning hair problems. There's still low body temperature. There's still weight gain, there's low energy. All of those things are still there. Now, some of them change a little bit to where you get a little bit of relief, but those problems are still underlying there because you never got to the root of that first diet domino causing the hormone imbalance in the first place. Listen, I believe 80% of hormone issues actually start in the brain. So it's not a Gland, like your thyroid gland, it is in the brain. And treating a final hormone like T4 or estrogen or insulin often misses the root problem and doesn't put an end to the symptoms for good. And this is why you continue to have you feel a level of chronic stress. There's a level of inflammation, right? And with that inflammation, you don't look as young or feel as young as you want to. And that's the key, is if we can start to fix things at the root, you will feel younger, you will look younger, your hormones will balance out, right? And these are examples of hormone cascade issues, because it's not just one hormone. It's many hormones that are impacting each other. So let's dive into the thyroid cascade. Now, here's a common scenario. Someone is exhausted, gaining weight, and just generally struggling, feeling overwhelmed, and they finally go to their doctor and get told, your thyroid is low, okay? So they're prescribed a thyroid medication. Their labs improve, but they still don't feel like themselves. One in four people on thyroid medication still report symptoms despite absolutely and completely normal lab values. And that's because what looks like a thyroid problem is actually a bigger issue. So here's what's typically causing this cascade. In hypothyroidism, it never starts with a thyroid, okay? In fact, hypothyroidism is almost always starts in the brain or the gut or the adrenals or the liver, okay? So everywhere, pretty much anywhere. But the thyroid is where thyroid problems start, okay? And for a lot of people, it starts with this hormone cortisol. And you have something called your HPA axis, your hypothalamus, pituitary, adrenal axis. And so your pituitary is impacted, and this is really where TSH is released that then impacts the thyroid. Your thyroid then releases T4. But then in order for your body to function properly, okay, for your cells and your organs to be fueled like they should, they need a hormone called T3. So your T4 that your thyroid produces needs to be converted to T3. And 80% of that conversion happens in the liver, and another 20% happens in your gut microbiome. And the pattern works something like this. The hypothalamus senses chronic stress, inflammation, or blood sugar swings, okay?
