
Why are so many women doing everything right: eating clean, exercising — and still feeling exhausted, inflamed, and hormonally off? If your labs look “normal” but your body doesn’t feel normal, this episode uncovers what’s being missed.
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Dr. Josh Axe
If a doctor is putting a patient on a statin for them not to immediately put them on Coenzyme Q10, it's.
Dr. Austin Lake
An easy thing to do.
Dr. Josh Axe
Yeah, yeah. Or metformin, vitamin B12. I mean, we know clinically that your body's completely depleted of those nutrients. We're nearing all those medications. Study after study's proven it. That's not happening. And so what are medications actually doing to the body versus if you're getting somebody on a vitamin, a mineral, herb, how is the body responding differently to those?
Dr. Austin Lake
A lot of medications that we are currently using, we found the natural form of that in nature and then we've patented it and created it synthetically so that we can sell it and make money off it. Right, and make a bunch of money off it. So when you start to see, you know, like metformin and the comparison would be like berberine, like having a natural substance that will help to improve insulin sensitivity but not necessarily reduce CoQ10 or vitamin B12 like you were saying before with metformin. And so there are examples of that where we've taken something that God has created, created a synthetic form of it that now has consequences for its use and patented it and made money off it. And that to me is where I'm like, that feels beyond irresponsible.
Host/Announcer
When I first got into clinical practice, the single biggest thing that surprised me was how many women are struggling with hormone based conditions. Everything from hypothyroidism and Hashimoto's pcos, endometriosis, infertility, menopausal symptoms, and so much more. And today I'm bringing on one of the world's leading experts in women's hormones, Dr. Austin Lake. And we're gonna be talking about how to heal and overcome the root causes.
Dr. Josh Axe
Of a hormone based conditions. Hey, Dr. Austin, welcome to the show.
Dr. Austin Lake
Hey, man, I appreciate you having me.
Host/Announcer
Well, hey, we had a great time.
Dr. Josh Axe
Hanging out in London. I know that, that was a great trip. You know, I had actually one of my favorite interviews I've ever done. We had a bunch of Barbara o' Neal on and she was amazing. And I know I got to hang out with you and Ben Greenfield and Dr. Chris Motley and Gary Brecke, Will Cole, so many people. And it was really a great event. And I really enjoyed getting to know you and hear more about what you do as a practitioner. And I know today that when I'm practicing and seeing patients, one of the biggest conditions or group of conditions we see are women struggling with hormonal issues. And today I want to sort of center the conversation around what's causing these hormonal conditions. How do you practice specifically to get to the root causes and what are some of the results you see and just get really practical today on helping women heal their hormones.
Dr. Austin Lake
Yeah, I think it's something that rightfully. So we need to talk more about even looking at research. Research isn't being done on women as much as it is on men. And so you start seeing these discrepancies whenever it comes to treatment to actually help solve problems. I think when we think about women, we think that women just are complex because they are a more complex than male physiology. And technically their hormones are very fluctuating. Right. Like they have a lot of diversities with each day, with each month. And so I think whenever we're thinking about women's health, we have to kind of start to look at them from a more in depth perspective. And it takes time to do that, you know. And I think a lot of practitioners, at least my initial experience getting into women's health was not because I had necessarily a passion about it, it was based on a need of needing to solve a problem for my patients. Right. Like, they come in, they have low energy, they're gaining weight. You know, they feel terrible, they're told that it's just part of being a female or it's just part of their. That time of the month. And yeah, it's a lot of language that puts them into a box to where they immediately feel like, well, I just got to tough it out. Yeah, I just gotta be. I gotta put on my. My brave face and just kind of prevail on. And I think as practitioners, we have to kind of appreciate what they're dealing with. And a lot of us, at least I never did fully, you know, at that time. So that was kind of my initial kick kickstart into women's health and seeing that there were root cause problems that were driving their health issues that weren't just, you know, because of like these random hormonal causes.
Dr. Josh Axe
Yeah. And one of the things I think people start to discover as practitioners when you're dealing with women's hormone issues is that cookie cutter solutions don't fix the majority of women. You know, a lot of times today, if they're in the conventional medical model, of course this doesn't fix it. It's just like, hey, here's a drug like birth control or metformin or something like that. I mean that's what a lot of the treatments are around versus and then sometimes you get in the more holistic space and it's hey, let's reduce inflammation or let's go gluten free or even keto or carnivore or some other sort of extreme diet versus saying no. The way that I look at it is I remember in science class, this was when we were probably in high school, they talked about how every snowflake, not one single snowflake is the same. Right. And it's the same with women, it's the same with men. I mean there are very, very specific. Now there are some similar patterns that are associated with certain conditions. But it's really critical to go and look at each and individual patient, look at their unique bio, individual needs, and really customize a protocol to meet those needs.
Dr. Austin Lake
Yeah. And I think if you have that perspective going into it, you can then evaluate, okay, like with this particular woman in front of me or man in front of me, like what, what challenges are they facing in their environment, in their day to day in the relationships, financially, you know, when it comes to what they're consuming, what they're not consuming. And if you don't, if you don't have that perspective, it's, I think it's impossible to really help somebody solve a problem. And if anything, you can actually create potential shame by saying like, hey, you know, you're really inflamed or like you need to eat better or you need to sleep better. But then you're like, well, how do I, how do I do that? Right? Because I have this busy life or I have a bunch of kids I gotta take care of, or I gotta manage the household and provide financially, like how do I actually change these things? Because if you don't provide a solution that's practical, like what are they supposed to do with it except feel like it just adds more stress and more shame potentially.
Dr. Josh Axe
Yeah. Well, again, I would hear this constantly in practice as patients would come in and typically it was funny early on in my career I was always like the 10th or 20th doctor that they would see. And now sometimes it's the first because people are starting to be aware of, I don't want to go this conventional route. I want to use food and herbs and lifestyle medicine to heal.
Dr. Austin Lake
But.
Dr. Josh Axe
But again, it happened so often where they saw another practitioner and they said something like, you need to eat better and reduce stress, and that's it. And it almost is more stress, because then you're trying to figure out, well, how do I reduce stress? Am I stressed out? They start overthinking, and sometimes it just actually makes it worse. And that's not to mention some of the other issues with. They'll go in and get blood work done, and their doctor says, hey, your blood work's normal, right? You're good?
Dr. Austin Lake
Yeah. It's like, well, now, okay, yeah, now I've done the work and I did these tests, and I'm still not seeing what I'm supposed to be seeing. So I guess it is just me. I'm just being a hyperbole hypochondriac, or I'm exaggerating my symptoms. But I think when clients or patients figure out that, oh, maybe we didn't look at the lab work through the right lens, or maybe we didn't add enough specific panels to this to kind of get a better perspective, I think it helps patients to feel some relief to know that, like, hey, I'm not a crazy person. Especially women.
Dr. Josh Axe
Well, you know, one of the things I've talked about, started to talk about pretty frequently, is that a lot of these blood tests today, number one, they don't test for the right things, number the right markers. And number two, a lot of this blood work, it shows that you're in normal range, but not that you're an optimal range. Somebody could be at a 30 level of vitamin D, and their doctor will tell them, hey, you're normal, you're good. But really, 50 to 80 or so is really where optimal function is happening. So even at 30, and if you.
Host/Announcer
Have multiple markers like this, let's say.
Dr. Josh Axe
Your vitamin D is borderline, zinc is borderline, even iron. We know that your immune system is not functioning at full capacity and your body isn't healing at the optimal rate. So this is something, I think, that's really important. Do you run blood work with patients ever?
Dr. Austin Lake
So, yeah, I mean, it's an online practice. And what we do is if our clients already have blood work, we want to look at that, we want to evaluate that. Oftentimes our clients won't have any blood work at all. And for us, all the information we can get is always better. Right? Like, we want to take as much as we can. What I've started to do and recommend is looking at like a total toxic test or total toxin test through like vibrant labs and places like that. Because I think it's a good way to kind of give them a different perspective on what could be challenging their immune system and can be challenging their mitochondrial health. And when they start to view it through that lens, they can see like, okay, I had a thyroid panel done and my TSH was at three and a half and you know, my, my T4 is at 0.7 and my doctor said these are normal, but yet I don't feel normal. But when we can look at it and combine it with these other components of, hey, it turns out you have some heavy metal toxicity or there's some mycotoxins present or there's some, you know, PFAS in your, in your, in your system, like that will complicate these numbers and make it more challenging for your body to actually heal and feel optimal. And when also when you're talking about labs having the understanding that as you were saying before, like normal doesn't mean that it's, it's normal physiology means that it's common within society. Right. Like those are common ranges that we will see for the population. Right. And so a vitamin D, like you're saying, of 30 is what we'll typically see. That's a non pathological state, you know, for, for the common person coming in. But the optimal state, as you were saying, is 50 to 80, you know, like that's where we want to see people. And so when our clients come into us, when we're working virtually online, we always want to start with as much information as we can get. If their doctors have already run, you know, thyroid panels or you know, hormone panels, which is rare, rare to see that most doctors aren't doing that. But if they're doing a common CBC or cmp, you know, we'll take that information, we'll look at it and do the best we can to help them create a game plan. But our job is always to help them get off of medications if that's what is wise and the best course of action and in alignment with their doctor. More times than not, their doctors aren't, you know, necessarily opposed to getting off medication, but they're not usually for it either, you know.
Dr. Josh Axe
Yeah, yeah, I found a lot of doctors, they're just not, they're indifferent. Yeah, they're non helpful.
Dr. Austin Lake
Right?
Dr. Josh Axe
Yeah, they're not. And I've told patients this for years that hey, if you do, if you had a doctor prescribing medication, I can't take you off that. That's something you have to work with.
Dr. Austin Lake
Them on, that's their responsibility.
Dr. Josh Axe
But also if they're unwilling to do it, find a different doctor who's willing to work with you and weaning you off and getting off of it.
Host/Announcer
Because I don't think that most people.
Dr. Josh Axe
Fully grasp how bad being on most medications is long term.
Dr. Austin Lake
When have you ever seen a medication? Medications aren't designed to heal or fix anything. I mean really, in reality, if you look at most most of them have a consequence to them, not a super positive benefit from them. Like it may keep you alive a little bit longer. If you have a heart attack, taking a nitroglycerin is going to be very helpful in saving your life. But taking a long term statin drug, there have been no real benefits. If anything, there's a lot of consequences to doing that long term. Specifically what it does to your mental health and seeing things like Alzheimer's and dementia rise drastically. So I think again, not to say that all medications are bad all the time, but long term chronic use, rarely do you see that it actually fixes anything. It creates more problems.
Dr. Josh Axe
I mean, there are every medication that I can think of depletes your body of something. And so if you're on it long term, and I actually consider this generally, I don't know that malpractice is probably too strong of a word, but I would say being irresponsible, that if a doctor is putting a patient on a statin for them not to immediately put them on Coenzyme Q10, it's an easy thing to do. Yeah, yeah. Or metformin, vitamin B12. I mean we know clinically that your body's completely depleted of those nutrients where, you know, those medications, study after study's proven it. That's not happening. And so what are medications actually doing to the body versus if you're getting somebody on a vitamin, a mineral, herb, sort of. How is the body responding differently to those categories?
Dr. Austin Lake
Well, if you think about it all, most, I shouldn't say all, but a lot of medications that we are currently using, we found the natural form of that in nature and then we've patented it and created it synthetically so that we can sell it and make money off it. Right, and make a bunch of money off it. So when you start to see, you know, like metformin and the, and the, I guess the comparison would be like berberine, like having a natural substance that will help to improve insulin sensitivity, but not necessarily reduce CoQ10 or vitamin B12 like you were saying before with metformin. And so there are examples of that where we've taken something that God has created, created a synthetic form of it that now has consequences for its use and patented it and made money off it. And that to me is where I'm like, that feels beyond irresponsible, you know, when we start thinking about that long term and we start to extrapolate that over the course of all these other different forms of medication where, and I don't want to open a can of worms on this topic, but where you look at how they use a lot of different, you know, different. They call them peptides, but a lot of them are actually venoms from different, you know, snakes and different, you know, like the Gila monster, like it's a lizard, you know.
Dr. Josh Axe
Yeah, there's a couple, there's examples of that.
Dr. Austin Lake
We're using these different mechanisms of action to create a suppression of symptoms within the human body that again, maybe it's yielding the result that you want for that particular symptom. But what are the other consequences that then unfold from that?
Dr. Josh Axe
Well, I think the other sort of philosophical reality here is that, you know, the dose determines the medicine or the poison. You know, what's happened a lot of times with medication is they have taken that extract from the plant and so it's an isolated compound now. So it's no longer, you know, curcumin from turmeric is an example. You know, okay, so now you have this and then we're going to take that and we are going to do an ultra high dose of it and it's going to be synthetic. So it's the difference of having raw honey versus high fructose corn syrup. Now, I mean, it's an ultra processed thing that's isolated where the dose is incredibly high. And I'll say this, and a lot of people aren't aware of this and people in the natural health community don't speak about this much. But if you do certain herbs in an ultra high dose, which your general supplement, it's almost never an ultra high dose ever. So it's almost something you don't have to worry about. But if you took something in a very high dose, I'll give you an example, berberine. If you did really high doses of that in Chinese medicine, it's known to really cool your nervous system and it's actually going to start causing some issues with your GI and your bowel movements. If you did a really high Dose long term. And so a very similar thing, metformin is a very high dose. I believe metformin actually comes from lilacs. French lilac. Yeah. But all that being said, the dose and what it's accompanying, what it's accompanied with is incredibly important.
Dr. Austin Lake
Yeah. I mean, they always say the dose makes a poison. But if you look at, you know, these different examples of how, you know, fluoride, for example, like, you know, they'll look at the different doses of this and saying if you consume this, it's not a big deal if you swallow more than this, like you need to call, you know, hazmat control or you know, your doctor and get, and get help. But I think the dose makes the poisoning analogy. I think, you know, I think, I think we're seeing a compounding effect that happens when we have a little bit of this, a little bit of that, and we start to have all these environmental poisons, toxins that get into our system and by themselves in isolated form, maybe not a big deal, but when you start to consume a lot of it or you combine it with other environmental toxins, you start to see a toxic soup that can go up.
Dr. Josh Axe
Well, yeah, there's no doubt that doses every day for a long period of time and multiple of other things that can be harmful are going to add up and cause issues to your point.
Dr. Austin Lake
Yeah.
Host/Announcer
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Dr. Josh Axe
Yeah.
Dr. Austin Lake
And so again, I think the medication thing, again, I'm not a physician. I'm not one of the people that would say I'm an expert on pharmaceuticals, nor do I want to be. But I also think it's important for the popic, the general public to understand that, you know, there are other natural forms that God created that are healing and don't maybe have the consequences that a pharmaceutical, patent and synthetic form of that same thing can have on the human body. And I always try to first focus on those things. And if you are on a medication and if we're seeing changes in your lab markers and your doctors on board, like we can start reducing that dose and maybe get off it, you know, safely.
Dr. Josh Axe
Yeah. One of the things I've always sort of described to people is that when you look at medications and a lot of cases, they're kind of forcing your body to do something that it doesn't want to do. I mean, you're forcing your body into something rather than kind of gently nudging it or creating an environment where it can thrive in a better way. You know, herbs, what they should be doing in most cases is just creating a more friendly environment. I mean, that's how it was used in Chinese medicine and Ayurveda and throughout history is, you know, for instance, if you're doing bitter herbs like gentian, it creates a more a drier environment, getting out dampness and candida and bad microbes. You know, a lot of those herbs that get rid of microbes are very bitter. If you've had like wormwood or black walnut, I mean, they're very bitter.
Host/Announcer
And bitter is drying.
Dr. Josh Axe
So now parasites and a lot of these things can't thrive as well when you move it out of that sort of damp, you know, microbe rich environment. So really, herbs are meant to just help change your environment so your body can better function in a better environment. Just like a plant will grow better. An environment with sun and water and then vitamins and minerals, you know, very different thing. It's just, it's just giving your body what it needs to function optimally.
Dr. Austin Lake
Yeah, yeah. And again, I think I always tell my clients, I want you to get your, I want your food to provide that as much as possible, you know, whenever, whenever you possibly can. But understanding that our soil is depleted, you know, like it's not the same that it used to be. When you have, you know, a vitamin, an orange, the amount of vitamin C has probably been depleted up 30, 50% compared to what it used to be. And so there are plenty of examples like that to where people are. I was one of these people 10 years ago, I'd be like, well, why do I want to have expensive urine? You know, it's like I'm just buying all these supplements for expensive urine. But the more I realized that we're not getting as much through our food as we used to and we're not getting as much through our soil. So vitamins and minerals and supplements take a very, very important role in our bodies. Getting what our bodies need to actually not just to survive, but to actually get into a thriving state. And a thriving state, for those who haven't experienced it since they were a kid, is an amazing place to be. You know, when you have mental clarity, you have energy, you heal and recover quickly. Your body can't do that unless it's meeting its nutritional needs on a daily basis. You know, you talk about, like daily bread from a biblical perspective, there's a daily need that that has to occur. And again, if you get chronic states of deficiency, people call it, you know, it's just part of getting older. But I really think that aging is just a. You have more time in a state of deficiency. Like, you're spending more time in this environmental world that's full of toxins, and then your body is deficient. And you're trying to, you know, you're trying to solve a problem that your cellular health can't solve because it doesn't have the raw materials that it needs. But if you give it the raw materials, you give it plenty of oxygen. Our bodies are designed to thrive for a long time, I think, but society, we've kind of lost sight of what that looks like because we've gotten so used to it.
Dr. Josh Axe
And hence, this is one of the main causes that we're seeing that causing female hormone issues in general and male as well. When you think about what the biggest root causes are, some of the biggest things you're looking for and you're seeing these patterns of this is caus causing the female hormone issues today, what are you seeing?
Dr. Austin Lake
Well, not to be too generalized, but inflammation is the biggest driver. I think when you look at things like pcos and endometriosis and subsequently infertility, which is a lot of what the hormonal female issues are, inflammation, is that the main culprit there? So then the question is, what is inflammation? For somebody listening, I'm sure your audience is pretty well aware of that. But for most people, they think of like, I sprained my ankle, it gets swollen, it's inflamed for a few days and maybe a few weeks, and then it starts going back to normal. But chronic inflammation is this destructive, repetitive cycle, right? Like that we get caught up in. And so for a female or for anyone listening, male or female, when you have inflammation, typically what you're going to start to have is higher insulin. You know, you have more of this insulin resistance problem that develops. And for females with endometriosis and pcos, high insulin is, in my opinion, the biggest driver of that. And again, there is a genetic component that can make you more susceptible to those types of problems. Especially with pcos, where you have more follicles in your ovary that are not being, you know, they're not maturing to a certain point, so they start to get immature and they start to kind of create some ovulatory problems. But for a lot of women, the main driver of that is higher insulin chronically. And then in my opinion, the driver of that is usually a high level of inflammation chronically. So that's where I see as like the primary driver for females. And then you add on top of it. You know, the source of that inflammation can be, you know, emotional stress, like having too much on your plate, you know, managing too much at home or at your workforce, or having poor sleep patterns or circadian rhythm undereating. You know, like, that's a stressor over exercising stressor. Um, so I, I always try to tell my clients, like, it's not just like you have, you know, you take some curcumin, phytosm, curcumin, like that's gonna fix all your inflammation. It's like, well, what if the source is coming from what's happening up here? Or like what's happening in your relationship with your spouse? Or what's happening every night before you go to bed and you're watching, you know, something on your phone, you're getting blue light simulation, and then you're not sleeping as deeply that night. And then you wake up and you drink a bunch of caffeine, you maybe skip breakfast, you go to the gym and then you go off and do your work. That's a huge source of stress and inflammation that I think drives not, not like a, not like a dysfunctional pathological state, but actually an adaptive state. And what I mean by that is when women have, let's say, pcos, what's happening is you're taking this progesterone that would normally help you to fertilize an egg, and you're creating androgens, right? Those antigens are going to be the result of that. And those androgens are essentially making you more male. Like, and to me, that's actually an adaptive thing that happens by design to help you survive the stressful situation that your body thinks you're in. So making a baby is not going to be productive, but maybe having more androgens or testosterone will help you to survive whatever the stressful situation your body thinks that you're in. And so again, I like to kind of give the body the benefit of the Doubt more times than not because about only 5 to 10% of hormonal issues are truly genetic. Right. And so we have 90, 95% of these things that are lifestyle epigenetic type factors that are influencing how your genes are being expressed. But we can't always blame these hormonal issues on genetics. We just can't.
Dr. Josh Axe
Yeah, yeah. You know I, I did a genetic test recently, I had my 5 year old daughter do it too.
Dr. Austin Lake
Oh, smart.
Dr. Josh Axe
And it was really telling, you know that there. Most people at this point have heard of mthfr. Okay. And that's a methylation spec looking at methylfolate and seeing how well your body converts into methylfolate, which is needed for methylation, thyroid function, a number of things. But there are so many other gene variants you can have. One that I used to see a lot in practice, still do today is hla. And that's really tied to your body being able to detoxify mold specifically. So a lot of times there's about 24% of the population where if they go into a moldy building or home, it just keeps cycling through their body because their body isn't good at binding to it and releasing it. But there's such great value in knowing, hey maybe what, what gene variant do I have? And sometimes you just don't even need a test. You just know, hey, I took this, I felt better or anytime around mold I have a problem. And you just generally know. But, but, but yeah, genes are as you and I have talked about so often, they're like they have to be turned on, there has to be a switch there and you can switch them back on or off based on to your point, lifestyle, you know, the things we're doing on a regular basis. Something else you said, it made me think of this when you were talking about inflammation being a big driver and then what was causing that in related to insulin and then stress and those types of things. But there is a, in Japan they operate now this really started in their motor vehicle division, but they would say, okay, if there's a problem with a car vehicle, we're going to practice something called the five whys. And we're going to keep asking why, why, why, why? Until we get to this was the actual root of it. And so for instance, with what you're saying, if you have a woman with endometriosis, maybe the first thing is, well, why does a woman have endometriosis? Well, there's inflammation of this lining. Okay, well why is there inflammation of this lining? Well, it's because insulin is spiking. Well, why is insulin spiking in this person in particular? Well, sometimes on blood work or looking at lifestyle, it's actually because cortisol. It's not you're eating too much sugar because your diet's perfect. It's actually cortisol's high. Well, why is your cortisol high? Well, because you're really, really busy and sometimes this is where we always end up with a lot of these conditions.
Host/Announcer
Why are you so busy all the time?
Dr. Josh Axe
Well, because I feel the need that I have to please people and say yes to everyone. And then it goes to childhood trauma. Because at one point in my life, my parents taught me that my worth and value was in how much I got done in checking off a task or something like that. But my point there is when we're doctors of root cause, we're looking at why, why, why, why, why. And the further you can get to.
Host/Announcer
The why, the bigger results you're going.
Dr. Josh Axe
To see long term with patients.
Dr. Austin Lake
And so absolutely, I think I couldn't have said it better myself. But again, having that perspective in your mind, you would think, well, that's going to take a lot of time to ask those five whys and to kind of dig with your patient. But once you do, and if you do that up front and you prioritize that, the amount of work that can be done, that can be expedited after that is, is exponential, right? Because now you're no longer like, tiptoeing around like all these potential problems. You're actually getting right to the meat of the problem. And I think for practitioners, I'm not sure many practitioners listen to this. Like, I can't express how important is just to take some time to like, ask. I've never thought of it that way of those five whys. But I think that's, that's a perspective I've always taken. But that's so important to actually get to the root, the true root of it. And it's not, it's not always just like, you know, if you obviously, if you have mold in your house, you want to get rid of that. You want to get rid of the source of that stuff. But how many those people have especially, again, this is why I like working with women. How many women have been told that they're just little men? You know, like, they're, they're, they're the same. They're just little men. They just have like smaller physiques. But the reality is, like, in God's design, they're totally different creatures, right? Like, women are, have a, they have the role of bringing life to this world and nourishing that. And men have this role of like protecting that whole thing, right? At least in my opinion, from a biblical perspective. And so if women think that they're supposed to be little men, that they have to just like toughen up and like, you know, pull their, their bootstraps, you know, up on their bootstraps, they're going to, they're going to go through life maybe telling their body to like, be quiet and like not listen to their symptoms and kind of just put on a facade of like, I may have this ovulation pain or I may have this, like this severe cramping that's like actually debilitating. But I have to be tough. I have to be a little man and kind of like push through and I have to kind of like overcome my own body's communication that's trying to communicate with me. And I think if we don't acknowledge what women are actually going through on a day to day or monthly basis, we're going to encourage this masking of their symptoms that then perpetuate the hormonal dysfunction that can exist after that. And I think men, especially as a husband, you know, part of the reason I got into women's health was my mom and my wife. And then now that I have daughters, it's just made it me even more passionate about it. But when you see like for my mom, for example, you know, she has an autoimmune disorder, adult onset stills disease, that I think was, you know, expressed after my brother had cancer. So her son had cancer and he was 14. He survived and all that. But it was extremely, you know, very, very challenging after that. My dad had several heart attacks and he went through all the stress that because he was working 80, 100 hours a week and trying to provide for everybody. And so my mom took on a lot of emotional stress and a lot of stress of taking care of the household, and she starts getting, you know, these symptoms coming out of nowhere and turns out it was an autoimmune condition. In hindsight, looking at it now, it's like, it makes a lot of sense to me at the time. Didn't make much sense to me at all. But the whole point of all this is that she took on all these extra responsibilities and worry and stress and anxiety and all these things of just trying to keep your son alive that I think, you know, some women just go through more than they're supposed to, you know, like they carry more weight than they're. They're supposed to carry. And especially single mothers or women who are, you know, working and taking care of the household. Yeah. You know, running kids all over the place and feeding them all this different stuff. I think that's why God created, you know, a husband or a spouse, a partner, to like balance that responsibility, take.
Dr. Josh Axe
Off some of the load. Yeah, yeah.
Dr. Austin Lake
And women don't get that. A lot of women don't get that offload because I think they. I think they think they're supposed to be something that maybe they're not. You know, it's like they're supposed to be able to take on all these responsibilities and just like tough it out. But the reality is when you tough it out, you are just inducing the survival mechanism that we're talking about. And I think this is where we see infertility. It skyrockets. Because why would your body want to make another human when you're trying to just keep yourself alive?
Dr. Josh Axe
Yeah. I think there's something to that, is that a lot of women are just trying to tough it out. They're just trying to tough it out and do more and more and more versus sometimes do less or take a pivot of do something really specifically in alignment with what God's called you to do. And this is true for men and women if we're operating outside of God's design and what he's uniquely called us to do. And it can be different for one woman versus another, one man for another. But I think that's an important thing. I think any operating in the lane that God's designed for you, there tends to be. Not always. I mean, I was going to say the word ease, but maybe a piece of knowing this is where I'm supposed to be, this is what I'm supposed to be doing. And that's so life giving. I want to talk about some other conditions specifically. So we talked about endometriosis a little bit. Talk to me a little bit more about the root cause of issues like in your mind, of hypothyroidism and Hashimoto's.
Dr. Austin Lake
Yeah, Well, I mean, again, when you look at the research, you know, 80% of. Of autoimmune issues are auto or not autoimmune. Hypothyroid issues are autoimmune driven. Right. So autoimmune thyroiditis and women are accounting for most of autoimmune conditions. I can't remember the stat. I mean, I think. Do you know the stat off the.
Dr. Josh Axe
Top of your head? Yeah, but it's much. It's like, it's. It's much higher.
Dr. Austin Lake
Yeah, it's like, you know, it's. Yeah, it's a ton. And so I think when we. The big thing that really triggered me back in the day when I started looking at this was like, okay, why are women, you know, proportionally more having issues with autoimmunity in general? Not even just hypothyroidism, but autoimmunity in general? Like, why are women more subject to hormonal imbalances? And, you know, why do women perceive stress 40% more than men? Like, you know, these are all things that really got me thinking about how can I help women truly solve these problems? Instead of just like, hey, you have a problem, good luck dealing with it. It was like, I have to provide the implementation or help them implement this stuff to be successful. And so I need to understand, like, what challenges they face on a daily basis. And. But when it comes to hypothyroidism, you know, you mentioned mthfr. That's a huge connecting point. When you look at the inability to methylate very well or take in meth, you know, meth, or essentially folate and use it for essentially creating glutathione and detoxing and creating energy. Like, all these things are. Are, you know, if you're burdened by mold, if you're burdened by heavy metals, if you're burdened by parasites, if you're burdened by, you know, just existing in a stressful world, if you don't methylate well, your thyroid is now, because it's a master gland, is having to compensate to kind of just keep again, to keep you alive. And I think when we start looking at, you know, obviously iodine deficiency can be a big role. It can also be a problem in thyroiditis. You know, we're making it worse. But there's a. There's a balance there, especially if you protect your thyroid of selenium. And there's some good ways you can do that. But for a lot of women, I think if you look at the HPA axis, which is your, you know, hypothalamus, your pituitary and your adrenal glands, and then you look at your thyroid, they're all working in conjunction with each other. And so if the brain is interpreting this stressful environment and again, trying to prioritize cortisol just to kind of get you through naturally, you're going to have some suppression of that T4 to T3 conversion, and it's going to Long term, it's detrimental. You know, it's called hypothyroidism. Short term, it happens all the time throughout your day. Like, if you were to look at a live analysis of your thyroid, you will see it fluctuates all day long, and that's normal. But when you see a trend of TSH and T4 and T3 and reverse T3 and all and all that, you'll start to see that, yeah, we're trending in the wrong direction. That's becoming more in a low functioning state. And in my opinion, again, it's protective. It's kind of like insulin resistance, where your body is pushing back against the potentially benefits of insulin. If it's chronic, it starts saying, hey, we can't keep doing this because we're not going to survive this if we keep allowing insulin to dictate. So we're going to become resistant to your effects. I think cortisol does the same thing. There's cortisol resistance, and so you start seeing that affect the thyroid. So a lot of women, I think, are in that state where there's deficiencies, there's environmental toxins, there's food sensitivities like gluten and dairy that can interfere with your thyroid, especially if it's autoimmune based. And then there's just the chronic state of circadian rhythm disruption and all that.
Dr. Josh Axe
Stuff, the way you started that. And this is where I want to just, I want to, I want to piggyback on this. And that is that why do women have more autoimmune disease than men? And I believe it's because women are more emotionally driven. You know, if you think about it like this, I mean, I mean, you know, this is typical if you're a woman or man, everybody listening here, you'll recognize this. I know for myself, you know, Chelsea is thinking, thinking, thinking, thinking constantly. And sometimes when I get home, it's easier for me to just shut my brain off and not think. I think about my mom and dad growing up. My mom was always thinking, always worrying, whatever, and my dad was just watching tv. Yeah, we're waffling. Yeah, exactly.
Host/Announcer
And so there's a lot more of.
Dr. Josh Axe
That, and in Chinese medicine, it's known, and this is the reality in all of our scientific community as well, is that when you're worrying and thinking constantly, it starts to drain energy from organs. It's draining your. It's causing cortisol to stay up because you're having to be alert while you're thinking like that. It Actually then impacts insulin. So all those hormones are affected if you are worrying, analyzing, obsessing, if your brain is on more and you're thinking. So I think that's a major driver. I mean, one of the greatest things women can do is try and turn their brain off, go for a walk, play pickleball, do lunch with a best friend. Because I think a lot of women, what's happened is, and you see a lot of women like this in your practice as well. It's like they have something scheduled from the moment they wake up to the moment they go to bed. And they're a full time, a lot of them, full time mom, full time chauffeur. Sometimes they're working as well, making food. I mean there's so many things and their whole day's packed. And so it's like there's just no downtime, you know. And so I think prioritizing rest and just doing things that you love, like scheduling peace just throughout the week, you know, that'll kind of, that'll get you out of it.
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Dr. Josh Axe
Yeah.
Dr. Austin Lake
And I think, I think as husbands, you know, there is this challenge and I did it with my wife one day where it's like it says something on the screen of like something that men can do that that women can't. And it's just like this, this guy like staring at the camera and the woman's staring at the camera as well. And the guy's just sitting there quietly, just, like, turned his brain off, you know, you can tell. And the woman's like, what? Like. Like, what are we doing? Like, what is it? Like, what are you talking about? Like, I don't understand it. And it's just like I did with my wife. And, you know, I think it's the same thing. Like, when you're driving with your wife, like, I'm not sure if you had this experience, but they'll gasp a lot. They're kind of like. Like, think you're gonna crash into somebody or.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
You know, they're something like that kind of.
Host/Announcer
Here, let me say this.
Dr. Josh Axe
Chelsea now knows that it bothers me. Yeah.
Host/Announcer
And by my.
Dr. Josh Axe
My wife of. And compared to other women, she's much more. Even killed emotionally. I mean, it's really like, I'm, like, astounded that she is so like that. So I have a wife that's less like that than probably others. Yeah. But I definitely have. I'm thinking my mom and sister more. They. They are, you know. Yeah.
Dr. Austin Lake
But, like, in my wife. We've talked with my wife, and she. She's pretty good about that. But there's. I've noticed, like, I don't do that ever. Like, that doesn't. I don't. I don't do that kind of stuff. But I've noticed with. With her and other women, their. Yeah. Their nervous system is just upregulated. Right. Like.
Dr. Josh Axe
Yeah. And I think there's a greater.
Host/Announcer
There's a greater level of women. And this is such a gift.
Dr. Austin Lake
Yeah.
Dr. Josh Axe
But it also can be used too much of just that awareness. I mean. I mean. And that's, you know, it's a form of emotional intelligence.
Dr. Austin Lake
Yeah.
Dr. Josh Axe
I mean, emotional intelligence is such a gift. It's such a blessing. Be able to know what's going on in your own heart, knowing what's going on, and perceive what's going on in the heart of others. Reading the room, feeling the room, it's such a gift. But it's like, you know, if you ever had the music on full blast, maybe you can listen to a song or two. Like that. Sure.
Host/Announcer
But if it's like that all the.
Dr. Josh Axe
Time and you're listening to that, it starts to just. You get brain fog. It's a form of stress when you think.
Dr. Austin Lake
So again, with women, there's a lot. So, you know, my wife's had four kids. You know, your wife has had two kids. Like, the stress and toll it takes to make a human and then provide care for that human for the first. Like, that's a two year process. Right. Until you're kind of out of the woods a little bit and you're sleeping a little bit and you're more consistent. So many women I've talked to, they start saying, like, yeah, like, I was on. I was on birth control for, for five, 10 years, and then I got pregnant and then I had a baby and I didn't sleep for a year or two. And then now, like, I had another baby. And then it's just like, now they're in their 40s and perimenopause hits and they're like, I don't know what happened and doctor wants to cut out my uterus. And it's like, you know, like, holy cow. If you, if you start to look back on, on all the things that led them there.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
It makes a lot of sense why their nervous system's dysregulated, you know, why they have deficiencies that haven't been met yet. Why their circadian rhythm is playing a huge role in their ability to heal and control the nervous system and control their absorption, these nutrients they're taking in. And then you start to add on, like, yeah, you gotta eat healthy. It's like, well, of course you do. But you also have to fix those other things that happened before all that.
Dr. Josh Axe
Yeah. Can I tell you something that happened recently too, just as an example of this to a degree. So Chelsea and I, we are, you know, we were in Puerto Rico for a time. We lived in Nashville for a long time before and then moved back to Nashville. We were in a home renting while we remodeled a home.
Dr. Austin Lake
Okay.
Dr. Josh Axe
And then in between, we ended up going and having to, like, do an Airbnb and live with family because we thought it was going to be done. Of course, all construction. You think it's going to be done in time. It's not. So we had a period of about two and a half months where we were not in our own home. And Chelsea and I wear oura rings when we sleep at night. And one thing that's tracked is hrv. Yeah. Well, Chelsea, we went and tracked, like, she went from being in a home that we're used to HRVs. She has great HRV in the 50s, stable.
Dr. Austin Lake
We go there.
Dr. Josh Axe
It's in the 20s.
Dr. Austin Lake
Oh, wow.
Dr. Josh Axe
I mean, we cannot get it. I mean, it's in the twenties for two and a half months. Finally, like, get comfortable in a home. And it took about a month after getting in there and then, oh, now all of a sudden it starts creeping back up and gets balanced again.
Host/Announcer
But like, my HRV didn't change. It made absolutely no difference.
Dr. Austin Lake
Isn't that amazing?
Dr. Josh Axe
Yeah.
Dr. Austin Lake
I think I've always said, I got told this in college. Like, men are like trailers. We're made to pull a heavy load. We pull a straighter with the heavy load. And for anyone that's pulled a trailer, that makes sense. But for women, I think again, as a husband listening to this, like, there's important things you have to consider if you don't know. First of all, your wife should know. If you're a female, you should know your cycle. Like, you should know what a consistent cycle looks like for you. A lot of women I've talked to, they don't even know what a regular cycle is for them. Right. And so they don't know if it's supposed to be 28 days or 25 or 35 or whatever. So you want to get a good idea of where your cycle is supposed to be consistently. Ideally, you know, day 20 is what would be referenced as obviously is optimal, but a day or two plus or minus is fine. But for men, I think we should also understand our wife's cycles. Like, we should know, like, hey, she's in the beginning of her cycle, she's menstruating or she's, she's about to ovulate. Like, she's in a really good time of her cycle where we can be a little bit more intense, a little bit more intimate. You know, we can have more, be more of these intenser conversations even. But if she's at the end of her cycle, beginning of her cycle, understanding how to love her well is something that I think men should take a class in because it's one of those things that it's not only gonna benefit her, it's gonna benefit you. And how you can kind of analyze that. She's not like you. Like, you have a 24 hour cycle. You're very consistent. She's up and down all throughout her day, all throughout her month. And again, when your body isn't able to make a human and you're trying to, you know, thicken the uterine lining and then thin it back down again. And then if it doesn't, you know, if you don't implant an egg and fertilize it, then you don't make a baby, then you start the whole cycle over again. Like your body is not for female, it's not going to be able to take exercise the same way at the beginning of the month versus the middle of the month versus the end of the month. It's not going to be able to take fasting maybe as well as it could at the beginning of the month and vice versa. So there's all these variables and factors that men have to understand about the woman. And again, for me, it makes sense. As a provider, I view myself as the head of the household, not in the sense of I get to have authority and dominate and rule over my. My family and dictate as, like a. As like a ruler, but I have the responsibility of providing protection and providing whatever nourishment or, you know, safety I can for not just my kids, but my wife. And when we had kids, every time my wife would have a baby, she would. She would just, like, protect them like a. Like a mother bear and just, like, have this, like, supreme level of protection. But I. The way I looked at my wife was like, I have the same protection over you so that you can protect our kids.
Dr. Josh Axe
Yes.
Dr. Austin Lake
And I think viewing it that way and telling her, this is how I view you, and this is how you are viewing your child, like, I view you the same way. So how can I love you? Well, because sometimes I think if we just ask the question, like, what can I do for you to love you? Well, like, what do you need? It provides a huge sense of relief to where the female doesn't feel like she's being a burden to you and she feels like she can get loved properly.
Dr. Josh Axe
You know, there's this. Communication is so key to great relationships. And I think there's this element of, you know, I think what women want is for men to ask that question. And most men, it's hard because there's such a lack of awareness in most men due to. Due to just never being, you know, brought up that way in the way you were fathered and not learning of these things. And so a lot of men just don't know to even ask. But then a lot of women know it, and they should probably ask, but they don't want to because they want the men to ask them and take the initiative. There's a cycle, and that's such a challenge. But I do think a message for all men here is, is that one of the greatest things you can do? I mean, I'm thinking about the book of Ephesians right now where it's saying, submit to one another. So thinking about Ephesians and Corinthians where it's like, love your spouse, and part of loving them is getting to know them Getting to know them, like, what are their needs? What are their heart's desires? What makes them feel safe? And you don't get to do that by asking them. I think most men just assume, hey, I'm providing, or I'm doing this and I'm here and that's enough. When typically women want more. And sometimes just you asking and them knowing that now you know, there's such value there. So I think that when we're talking about this conversation about women's hormones, it's about getting the root cause of women's hormonal issues. There is an element of, you need to eat these foods. These supplements can be beneficial. But there are also such an element of awareness of the woman in knowing her cycle and her needs. The manifestation, becoming more aware and loving his wife and protecting her in that way, too. That just is so important. Yeah.
Dr. Austin Lake
And I think, again, it doesn't need to be. It's not a drastic change. It's just like you said, the awareness, I think, is the key word there. If you have the awareness of where she is or the awareness that maybe she's taking on more than she should. At least for me, when I get out of my little compartmentalized brain and I step into this other compartment of caring for my wife, I'm like, oh, obviously I want to. I want to do whatever I can to love you and support you. Like, tell me what I can do. Like, I want a task that to get done. But having even the ability to ask that question or the awareness to ask it, and then having your wife reciprocate and tell you specifically what she needs, I think is a game changer for marriage.
Dr. Josh Axe
For marriages.
Host/Announcer
Yeah.
Dr. Josh Axe
And there's always kind of two steps to this. And even in health as well, in the very same way, there's awareness and then once you're aware, taking action, doing the right thing. Right. Because, I mean, I see this in patients. When I take care of patients, if somebody sees great results, it's because of one of two things. If they don't, it's because of one of the two things. One, if they're not seeing results, sometimes it's because they're just doing the wrong thing. Like, I see this with women a lot with hormone issues. They think I should be eating healthy. So that means a lot of salads and a lot of smoothies.
Host/Announcer
And it's like, well, that typically is.
Dr. Josh Axe
Actually messing up your digestive tract. We need to do more soups and herbal teas and sweet potato. So a lot of times it's just they're not aware that they're not doing the right thing. And then sometimes they're aware of, okay, I need to be doing this, but I'm not going to follow through and do it. Maybe because I don't have, I have a poor sense of self esteem or there could be all kinds of things there that are driving that. But again, it's so important to become aware of what do you need? What vitamins do you need, what minerals, what foods, what, what do you need? And then having a plan and being able to actually follow through with what those things are.
Dr. Austin Lake
I always call it the two eyes. You know, there's ignorance and iniquities. You know, ignorance are the things that you do unknowingly that are harming you. As Hosea, chapter four, verse six says, God, you know, God says my people are destroyed for lack of knowledge. Like we need to know what we don't know. Very important. And then iniquities are things that we do knowing they're bad for us and we do them anyway. And I think that's a spiritual issue of not loving yourself, not honoring God with your body, not, you know, all these different elements that can go into your self worth and your trauma and your childhood history, all that different things. And so I think, yeah, there's the two eyes. And I think if you can have that perspective with your patients or with yourself, for me it's a game changer because then I can identify like, what is the problem here? Is it a lack of knowledge or is it a lack of self care or self worth?
Dr. Josh Axe
Yeah, yeah. You know, one thing, it was funny because I, as part of my, the health institute where we see a lot of patients coming in and we do blood work and look at all these things. I have practitioners, I've trained. And one of the things, when I came in there and started training them, one of the things I think they were most surprised by is. And I had one of them say this to me, they said, when I.
Host/Announcer
Become a practitioner, I didn't know I.
Dr. Josh Axe
Would need to be like a therapist and psychologist, a theologian probably. Yeah. And I said to them, I said, listen, everybody needs advice on diet and this awareness piece as we've been talking about.
Host/Announcer
But also people need hope.
Dr. Josh Axe
I mean, I've found this in practice. So many people come in downtrodden and they've tried. I mean, a lot of people have been working hard. Oh yeah, they're exercising hard. They've been following diets, they've been taking and they're Just they're a little bit worn out oftentimes mentally and emotionally, and a lot of them have lost hope. And I said, one of the, you know, what we also have to bring is we have to bring hope. We need to bring good counsel. We need to help be able to coach people in reducing stress and lifestyle. Like, one thing we do with most patients is we'll give them a list of, if they want to. This is optional, but Bible verses to meditate on. Like, if they're struggling with worry and that's causing GI issues, hey, here's 10 verses we just want you to meditate on daily. But it is important as practitioners, the best practitioners, they're not just recommending one supplement or a fad diet. They're really going through more of this holistic body, mind and spirit support for people in that way, too. Another condition I want to hit on, that I know that you've talked about before, is menopause. There are so many women struggling with menopause. I think that before, here's what happened for a lot of years, women would say, I'm just going to deal with it and suffer through it. And they didn't know what to do. And then there's been times where some women felt, okay, taking hrt. Okay, I would love to get your opinion on what's the root cause of menopausal issues from the way you see it, and then also get your opinions on hrt.
Dr. Austin Lake
Well, I think menopause in a state of health is you go from a fertility state to a stability state. And so that's kind of cool if you go from having a lot of fluctuations to now being very stable with your hormones. The benefit is you can now be a source of stability and wisdom for the people around you. And I think that's. That's the beauty and the optimal side of menopause that doesn't maybe get talked about enough. And I think that's by God's design. Obviously, the dysfunctional side of it is all these things that we just talked about that's happening in perimenopause or even before that, when you're younger, going into menopause that hasn't been corrected. And now menopause, what typically is going to happen is you're going to start to reduce your production of progesterone in your ovaries. Right. And so progesterone is that calming stabilizing hormone that creates that balance between estrogen. Right. And so if estrogen is going unopposed and it's now creating an estrogen dominant state, you're going to create more of a discrepancy between estrogen and progesterone. That in my opinion, makes you more susceptible to stress. It makes you more susceptible to all these environmental factors that can make you feel worse. And so for a woman who's going through menopause or perimenopause and the gap is widening, that's a problem. But what happens when you go through, when you're postmenopausal is now your estrogen starts to go down lower. Right. And so you have low progesterone and now declining estrogen. And that's where you start seeing a lot of issues with osteoporosis, osteopenia, to where your bone health is not being, your bones aren't being protected, you're more at risk for cancers. And I think that's where you start to have longer term problems. But like, while you're transitioning through menopause, a lot of women, again, they go on to HRT because they never corrected anything before this. And so they have to get some relief from, from hot flashes or from the crazy mood swings they're experiencing or whatever, inability to sleep. And so if you don't make enough progesterone in your ovaries, I think what I always tell my clients is you start to make it in your, you only make it in your adrenal glands. And your adrenal glands are now, because they're dealing with the stressors of the world and the demands of the world of like, oh, we have a stressful situation. Make more cortisol. If you're gonna make more cortisol, you're going to decrease progesterone.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
And that's when you start to see an immediate like, oh my gosh, I'm feeling really flushed. I'm feeling very like an adrenaline, adrenaline rush basically, because that's kind of what's happening. And so for a lot of women, if they're eating foods that, that worse than that, or they have insulin resistance or, you know, maybe they're not getting good consistent sleep, or maybe they're getting, you know, they wake up and they drink some caffeine and they don't eat a good protein fat rich breakfast and now they have, you know, dropping blood sugar that's going to spike cortisol even more. And so all these things create more of a, of a worsening of that progesterone to where you're being, you're going to be more susceptible to the menopause effect, I guess.
Dr. Josh Axe
It's such a great job explaining that too. And one thing a lot of people don't realize is that this balance of progesterone, estrogen, it's almost like again, this is a very different category of health. But this omega 3, omega 6 balance, right, you have to have a balance there in a certain ratio or there's inflammation and things are, things get off, you know, one thing I think I've noticed when I think about the women I've taken care of with breast cancer in particular, I feel like the most diagnoses. And again, I don't have a statistic on this, I'd be interested to look this up. But a lot of times it happens in the 40s. And the 40s is this perimenopausal time too, when sometimes progesterone is dropping and estrogen might even stay a little bit higher and you get this estrogen based breast cancer. But again, I think, and that was my mom, 41 years old, in that phase, diagnosed with breast cancer. But progesterone acts sort of as a protectant buffer to estrogen as well being high. So I think to your point, that's incredibly important. You know, when I was talking to Barbara o', Neill, one of the things when we were talking, I asked her, I said, hey, what do you believe in all the women you've seen, the biggest cause of hormonal issues is from a hormone standpoint. And she really pointed to progesterone and she talked about using wild yam cream. I mean, this is something that's been used in Chinese medicine in Asia for a really, really long time. But I do think it's a hormone that probably needs even, we need to pay even greater attention to, of how can we support progesterone in particular in that way. But I love the way you described sort of what's happening in Chinese medicine. The way that they view it is when progesterone and estrogen both drop, those hormones are partly responsible for cooling and moistening the body. And this is why you get hot flashes, this is why you get dryness, is those hormones. And so in Chinese medicine they'll say eat more. What we call yin built. And so yin is more feminine, yang is more masculine. But yin tends to be bananas. And even dairy and sweet potatoes are on that list. And things that sort of in a lot of Omega 3, a lot of good oils because those help bring moisture to the body.
Dr. Austin Lake
Yeah, I love the way you describe that. And I think when you hear that, the cooling effect in my mind From a Western medicine perspective, I mean, that's the only thing I was really trained in. It makes sense to me when you say cooling. And so I like that, that I like that perspective of, of just how to support somebody. And I think for the, the person hearing that, hopefully it, it kind of resonates on what you can do. Right. Like, I want people to hear this and be like, okay, what can I do to fix this? And so when you talk about, you know, fibers, fiber is something that, again, depending on your GI tract and what, what benefits you, fiber is very helpful. At least 25, 30 grams a day are helpful at binding estrogens and removing them out of your GI tract. Right. And so I, this is where, again, having, having a diet that you're like, okay, what does it look like to eat healthy? I always assume that, like, people know what that looks like. Right. And I'm sure you probably do. Maybe you've been.
Dr. Josh Axe
No, here's what I've realized. No, I don't think that at all.
Dr. Austin Lake
Yeah.
Dr. Josh Axe
And the reason is it's probably smart.
Host/Announcer
Because it's what I talked about earlier.
Dr. Josh Axe
I think that I am so ingrained in personalized nutrition. Like, I found that, you know, somebody with cancer versus irritable bowel disease, those are completely different diets. A woman that's in her 20s versus a woman that's in her 50s, that's.
Host/Announcer
Oftentimes a really different diet. Like, a woman in her 20s, I would almost never recommend.
Dr. Josh Axe
They have soy.
Dr. Austin Lake
Right.
Dr. Josh Axe
A woman in her 50s or 60s. Wow. Organic soy, man. That's a flax.
Host/Announcer
Those are great foods.
Dr. Austin Lake
That's a good point.
Host/Announcer
So, no, I mean, actually, my state is typically that the person probably is.
Dr. Josh Axe
Doing not the right thing dietarily, because.
Host/Announcer
Generally most people aren't.
Dr. Josh Axe
I mean, in terms of a percentage. So I do think people learning the exact right diet for their body. So when I'm customizing nutrition plans, I'm very aware of, okay, I looked at your blood work, I looked at your tongue diagnosis, looked at your history, looked at all of this. Let's create the exact ideal foods and make sure you're getting all of those in your diet in order so you give your best chance of healing.
Dr. Austin Lake
Yeah. I call it for our clients, like a diagnostic diet. You know, it's like we want to figure out what. What works for them. And again, you don't really know that until you diagnostically implement something and then start to work through a progression.
Dr. Josh Axe
That's right.
Dr. Austin Lake
It looks at. And so. But again, I think for the person Hearing this, it's like, you know, again, whether it's, you know, I personally like to ascribe to more of a, again, I like to kind of do a combination of either like a low fodmap up with an autoimmune protocol with something else.
Dr. Josh Axe
Right.
Dr. Austin Lake
And just kind of like figure out where to start for them.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
But what that looks like is if you're just hearing this, it's typically going to be, you know, no gluten or dairy at least. Definitely no conventional gluten and dairy. Like where it's hybridized wheat and conventional raised dairy like that. That to me, if you have, especially if thyroid issues so beneficial to at least eliminate that potential source. Right. And get some diagnostic data on how you do without it. And so for a lot of people, I think, think if they don't understand how their immune system is functioning. Your immune system has memory to it. Right. And so that memory has a half life to it to where typically a three to four week time period will allow for. If you have something out of your system that's not challenging, your immune system for three to four weeks can show some signs of improvement to where it's like if it is a dietary trigger, you should feel better by having this out at the four to five week mark, potentially. Right. And so that's useful information for somebody to know. I can't cut it out for seven days. Maybe I'll feel better, but if I'm not feeling better, it's not because I'm not on the right track. Maybe I am on the right track and I just haven't given enough time to start seeing that this does trigger my immune system or this does trigger my GI distress or whatever. And so that's really important to communicate, at least in my opinion, to my clients to say you need more time, you got to give it four to five weeks. But what I was saying with the fiber thing, but because estrogen can get recirculated very easily from your GI tract and also can get trapped in a lot of your fat cells. A lot of our clients that have gut health issues have high beta glucuronidase. Right. And so beta glucuronidase is one of the things that helps to bind and remove estrogen from your GI tract. And so for people that are not fixing their GI tract and then just going on HRT or trying to transition through menopause, and they're not actually fixing their gut, they're not fixing their circadian rhythm, their detox pathways are blocked, maybe they had a gallbladder removal. They don't have good bile synthesis and bile flow, or maybe they have lymph stagnation, or maybe they have some kidney function, kidney dysfunction, where they don't clear out toxins from their kidneys. They're not going to be good detoxifiers. Right. And so they're going to be likely to recirculate a lot of this estrogen or other toxins that when they start to lose weight, which is a good thing right now, all of a sudden, they yo, yo very frequently, because they lose. They break down their fat cells, they release the toxins, they get circulated, and they just go right back to where they were, and they start to yo, yo very quickly. And so this is where I say it's. I would rather my clients, I always say, first get healthy, then get fit. You know, like, I'd rather you focus on detoxing. Well, fixing your diet, you know, removing things from your environment that would. That would trigger your immune system. And then once you want to start cutting, Cutting fat and getting in the gym and start building muscle, like, you can do it from a. From a stable foundation.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
But a lot of people, they, they. Especially this time of year, the gyms will open up, and New Year's, they all jump in the gym, start killing themselves in the gym, working out a ton. And none of the existing foundational problems have been addressed. And so now it's like they get injured quickly, they can't exercise very long, they get burned out very fast, and they don't recover. And next thing you know, they're just like, I, I'm trying. I'm doing what I'm told to do with diet and exercise, but I'm not actually getting any results. I actually feel worse now when the reality is if you fix some of those foundational things before you get really intense in the gym, I think you have a lot more success by doing it in that order.
Dr. Josh Axe
Yeah. Yeah. I think the idea is, play the long game. You're always going to be more successful the further out you thinking. Eternal thinking about when you're in your 80s, thinking about 10 years from now, you're going to be better off. And so thinking about, hey, what are the habits I can create that I can actually stick to and be doing these same habits in the same daily routine in five years. So I think the more you can think like that of, hey, what's doable? Not only now, but I can do this throughout this entire school year or year, that's gonna be a better mindset and more successful.
Host/Announcer
Hey, if you want practical, science backed guidance for living a healthier, longer, more vibrant life, you need to check out the biohackit podcast. It is hosted by my good friend Aman Hassan and it brings a thoughtful, compassionate perspective to wellness that so many women have been looking for. Every week, Aman breaks down the list. Latest research in longevity, hormones and metabolic health in a way that's clear and easy to understand leads to important conversations around women's health, fertility and the steps women can take to protect their energy, balance their hormones and support long term well being. She talks with top doctors, scientists and health experts about natural healing, nutrition, lifestyle choices that make a real difference. Ann sits down with entrepreneurs and thought leaders to explore how they stay strong, grounded and resilient in their personal lives and their work. If you want a show that speaks directly to health challenges, women are navigating today while offering hope, clarity and real solutions, tune in to biohack it every Thursday. Wherever you listen to podcasts, it is one of the most educational and uplifting shows in the wellness space and I.
Dr. Josh Axe
Think you're going to love it.
Dr. Austin Lake
I was listening to Jelly Roll, you know, you hear about him, he's on Joe Rogan and he's lost like 300 pounds. Yeah, so he was 500 pounds and I think now he's down to like 260 or something like that. So he's lost 250 pounds, half his body weight. And he said, you know, he's like, if I thought about all the weight I had to lose, it was like, it was overwhelming, right? Like it was too big of an elephant bite to take. And he's like, I started focusing on like, how can I lose eight pounds, you know, like in this next two to three weeks. And eight pounds for a 500 pound person is not very much, right? But you know, those small incremental changes, those incremental goals, I think is how we have to look at it. So for somebody listening to this, I would say, you know, how can I be consistent with my bedtime? Like, I'm gonna go to bed at 10 o' clock every night and I'm not gonna, I'm gonna let my body wake up naturally if I can, you know, if I don't have to miss work and stuff like that. And then from there it's like, well, how can I, how can I wake up and consistently drink water? You know, just like get some water and some minerals added into my, my filter or for into my body each and every day before I have Coffee or how can I wake up and, and have a breakfast? This is my recommendation at least is eat some food before I have caffeine. You know, like, how can I do that consistently? But if you start doing those little things and you have the belief that, that by doing it consistently and being boring with your life, like it actually yields results if you play the long game like you're saying, because if you're trying to solve a problem in three to four months so you can get fit for a wedding or something, that's going to, you know, be a one time event, you're not going to have the right, you're going to be, you're, you're in trouble from the get go, I think. But a lot of people, if they have the mentality of, I may be 45 right now, when I'm 55, 65, I want to be a healthy fit grandma or healthy fit grandpa and be a good example to my kids or grandkids and how to be healthy. That's my long term goal. Like I got 20 years to be consistent with these little incremental goals that I'm focused on. And that to me I think creates a lot of like leeway for grace for yourself and not putting a lot of, you know, feeling a lot of shame for not meeting your goals. Because I think a lot of women that invest in their health and don't meet their goals, they feel a lot of shame for it. You know, they just told her husband, like, I'm gonna, I'm going for it this time. I'm commit to it, gonna, gonna achieve my goals and be healthy. And then something doesn't work. You know, they fall flat on their face, they bit off more than they can chew. And then they spent a bunch of money on their, their health and they never actually achieved anything. That's gonna create a propensity for not wanting to take chances down the road for your health. Like it's gonna make you a little bit scared and skittish. And so I think it really is important to identify what your initial goals should be. Make them very small, tangible, achievable. And once you start feeling better, the bigger goals become easier to solve.
Dr. Josh Axe
Yeah, you know, it's so, it's so true. Yeah. Give me your top foods and supplements to support women's hormones.
Dr. Austin Lake
So foods. I love sweet potatoes. You know, I think I have all my, a lot of my meal plans have sweet potatoes built into them. My, my family, my kids are like so sick of sweet potatoes because we eat it all the time. But I think they're great. There's also, there's also different types of sweet potatoes and there's like purple, there's white, there's yellow. White are typically more lower glycemic index. So like they could be a little bit better for somebody that has, has blood sugar issues. But overall I think a sweet potato is fantastic for stabilizing blood sugar. It's a good source of fiber, some good phytonutrients. I love sweet potatoes a lot. And you know, they're not quite the same as yams. You know, wild yams are a little bit different, but there is a little bit of a component of, of helping progesterone production slightly. So there's, there's that benefit. Huge fan of, of berries. You know, I think berries are great antioxidants. They're great adding to your, to your meals as a little sweet treat at the end of your meal. Avocado. Big fan of avocado. It's a great source of monounsaturated fat. My kids eat that. So what we typically eat is like ground beef, you know, grass finished grass or grass, what am I trying to say? Grass raised or.
Dr. Josh Axe
I mean it's typically grass fed. Grass finished.
Dr. Austin Lake
Grass finished.
Dr. Josh Axe
Yeah.
Dr. Austin Lake
So we're a big, I like most places if you go locally, locally sourced, you can find, you know, grass finished beef. And I think if you're buying internationally, but across state lines, there's sometimes some regulations where it's hard to do that. But I've found every place I've gone you can get grass finished beef. And that's a big staple for us. And so we'll do that. We'll do sweet potatoes, we'll do avocado, we'll do berries. Eggs are tricky. I think if they're conventionally raised, store bought eggs, it's like you lose that protective, they wash that protective coating off the egg in order for them to be stored. One of my clients was a scientist and she studied eggs and how they're all manufactured and processed. And she said that basically all the eggs that you buy in the store, they all kind of go through the same process to end up in the store to where they are meeting their standards. And so if you have farm fresh eggs, they have that protective coating, they can sit on a countertop for weeks and not go bad a long time, months. But store bought eggs you have to put in the refrigerator. If you don't, they go bad because they lose that protective coating. Then also depending on how they're raising the Chickens, what they're feeding them, what they're injecting them with. In terms of vaccines, it definitely can affect, in my opinion, the quality of the egg. And so for somebody consuming eggs, I really want to figure out, again, diagnostically, how do you do with eggs? Because eggs can be a great source of nutrition, but if you don't do well with them, if your immune system doesn't do well. I don't like eggs for some of my clients with autoimmune issues.
Dr. Josh Axe
Yeah, it just depends.
Dr. Austin Lake
Yeah, yeah, so it depends on that. But eggs are sometimes a food that we'll consume and recommend, but otherwise, yeah, those are like, some of the basic foods I like for my clients and for hormones. I think a lot of women don't get nearly enough protein with their meals. You know, they're getting very insufficient amounts. And so if you have to substitute with a protein supplement, I like them to do that after they've consumed food. Personally. Yeah, I think chewing your food is really important. I think if we're only relying on meal replacement smoothies and shakes all the time, you can start seeing some digestive issues potentially. So I like them to chew first and then can subsidize a little bit after that with protein powder if they need to. A lot of my clients don't do whey because it's dairy, but if they. If they can tolerate, that's fine. Otherwise, like a hydrolyzed beef. Bovine protein source is pretty good. Some pea protein sources are good, but, yeah, I think protein. I know you've. You've probably talked about this a ton on your podcast, but I like at a minimum of 100 grams of protein per day. Yeah, preferably, you know, it needs to match their body mass or muscle mass, you know, how much muscle mass they have. But overall, I think those are the big ones. A lot of women think they're eating enough protein, and the reality is, like you said, they eat a salad for lunch. You know, maybe they have, you know, like a smoothie for. For breakfast that's heavily based in, like, sweets or not sweets, fruit, fruit, you know, spinach, all that kind of stuff, and no protein. And then they have their caffeine, then they have a salad for lunch, and then they have a big meal at the end of the day, and it's like, you know, it's a hard. Hard for your insulin to manage that and for people to understand that insulin sensitivity is going to get worse as the day goes on. As the sun starts to set, your insulin sensitivity gets. Becomes less. And so that Means you're not going to be able to utilize the, the, the energy coming in and, and store it properly. Right. And so a lot of people are eating later into the day and then they're more likely to store that as fat. So eating with the sun is usually what I say eat. You know, 80% of your calories before 2 o' clock is typically like a, a rule I like to give my clients, but it's not required, just something for them to think about. And then when they do that, yeah, I think they start seeing a lot of energy improvements throughout their day. They start feeling like they recover faster at the gym and it's an easy thing to do once you get in rhythm with it. As far as supplements go, you know, my, my big ones are, I love a B complex. I think B complexes are great, especially because most women have mthfr. I think a methylated B complex can be very a game changer for a lot of people. You know, you do get a lot of these B vitamins from, from, you know, meat sources and things like that. But I think a methylated form that's more easily absorbed and gets you the dosage need to kind of meet the, meet the demands of your day. Like I have mthfr, my, my wife has, so our kids have it. Right. Like I see huge changes in my kids and sometimes I'm like, why did I give them a B complex? Or they're already crazy, like they're crazier now, but they have so much energy, they, they can run all day long. And you know, just in terms of daily detoxification, daily energy production, mental clarity, you know, even helping with your thyroid and helping with your sleep and helping with your anxiety. Mental health clarity. I think it's very important to have a good methylated B complex. Magnesium's my favorite mineral. You know, like most people, I'm a big fan of magnesium glycinate. I think it's, it's easier on the digestive tract, doesn't cause much nausea or, you know, discomfort in your gut. You can either typically take it on an empty stomach. But magnesium, there's a bunch of different forms of magnesium, like 3 and 8 and citrate, that could be useful too. So all those are up for discussion. Vitamin D, obviously, K2, most people are very familiar with that term now and kind of what that means, but I say typically 5000ius is a good place to start. Yeah, omega 3 fatty acids again are another favorite. You know, I think the population is experiencing about a 20 to 1 ratio of omega 6s, omega 3 fatty acids. And it should be closer to like a one to one ratio typically. And so, so I think we're way out of balance there. Whether it's through an Omega 3 fish oil supplement or you're getting it from somewhere else. I'm not sure what you Recommend for Omega 3.
Dr. Josh Axe
Listen, I typically like classic cod liver oil, like a good quality brand most of the time. But yeah, I think that omegas are up there. I mean, from a clinical standpoint, when you look at studies, one of the most beneficial long term is definitely going to be omega 3s and fish oil. So, yeah, I think those are. Sure, yeah, I think that's a great list. I think the B complex in particular because that's so important for liver function. Right. And detoxification and to your point, methylation, that, that's something that when we're talking about women's hormones that a lot of women can benefit from too.
Dr. Austin Lake
Yeah. And it's hard with hormones because once you get some specifics of pcos, you could look at Inositol as a great supplement to take for pcos. If you do have endometriosis, you can look at that like that. Anti inflammatory phytosom, mervir curcumin can be helpful for that if you have, you know, high. If you're not detoxing estrogen very well, like dim can be a great supplement to take. But those are all kind of specific to the, to the condition and the person to where I have a hard time making a statement about those types of supplements. And so that's where I usually don't.
Dr. Josh Axe
Go down the road. It's what we talked about earlier. Women need personalization. So I wanted to get a general hormone idea. But yeah, with every one of those individual conditions, there are specific supplements that they would need that are best going to help them address the deficiencies so they can function optimally. So I think there's so much wisdom there.
Dr. Austin Lake
But those first ones I mentioned, I feel like those, if you're anyone, like most people listening to this, can take those to some degree and they'll find benefit tremendously.
Dr. Josh Axe
Yeah, those are foundational. They're foundational. Well, Dr. Austin, I want to say thanks so much for coming on today. I really enjoyed this conversation. I have so many people that listen to the show here who want to optimize their hormonal health. So many women in particular. So really glad you were able to come on because I know you've worked with so many women and helping them with their hormones, and it's just an important topic in conversation. I wanted to say, hey, thanks, everybody, for tuning in here to the Dr. Josh Axe Show. Every week, we're diving deep into the science and principles of how you can heal physically, mentally, spiritually and take your health and your life to the next level.
Host/Announcer
Hey, don't forget to subscribe.
Dr. Josh Axe
It's the number one thing you can do to support the show. So thank you for all subscribing, thanks for sharing, and I'll see you on the next episode.
Guest: Dr. Austin Lake
Host: Dr. Josh Axe
Date: February 12, 2026
Dr. Josh Axe welcomes Dr. Austin Lake, a leading expert in women's hormones, for a deep dive into the epidemic of female exhaustion, inflammation, and hormone dysregulation. They explore why women’s health issues like hypothyroidism, PCOS, endometriosis, and infertility are so widespread; criticize the pitfalls of mainstream medical approaches; champion personalized, root-cause-focused natural care; and offer practical tips for both women and their families to restore hormonal health, physical resilience, and life satisfaction. The conversation is rich with clinical anecdotes, research insights, humor, and actionable advice.
Autoimmunity and Hypothyroidism
Menopause & Perimenopause
On the limits of pharmaceuticals:
“Medications aren’t designed to heal or fix anything... Rarely do you see that actually fixes anything. It creates more problems.”
— Dr. Austin Lake [11:14]
On the five whys and the true cause:
“When we’re doctors of root cause, we’re looking at why, why, why, why, why. And the further you can get to the why, the bigger results you’ll see long term.”
— Dr. Josh Axe [26:28]
On women’s hidden burdens:
“Some women just go through more than they're supposed to, you know, like they carry more weight than they're supposed to carry.”
— Dr. Austin Lake [29:55]
On practical lifestyle changes:
“How can I be consistent with my bedtime?... How can I wake up and consistently drink water?... Eat food before I have caffeine... those small incremental changes... if you play the long game...”
— Dr. Austin Lake [63:46]
On protein needs:
“A lot of women think they're eating enough protein... reality is... a salad for lunch, a smoothie for breakfast—no protein—and then a big meal at the end of the day. It's hard for your insulin to manage.”
— Dr. Austin Lake [68:45]
On hope and holistic care:
“What we also have to bring is we have to bring hope... The best practitioners ... are really going through more of this holistic, body-mind-spirit support.”
— Dr. Josh Axe [50:09]
| Timestamp | Segment/Topic | |-----------|-----------------------------------------------------------| | 00:24 | Nutrient depletion from meds; conventional medicine flaws | | 03:12 | Unique female physiology and need for individualized care | | 07:47 | “Normal” labs ≠ optimal labs | | 20:53 | Root cause: inflammation, stress, insulin resistance | | 26:28 | Using “Five Whys” for true root-cause diagnosis | | 29:55 | Women’s hidden emotional and physical labor | | 35:54 | Mental overload and importance of rest/play for women | | 53:51 | What happens during perimenopause/menopause | | 66:18 | Dr. Lake’s top foods for women’s hormones | | 68:44 | Foundational supplements: B complex, magnesium, D, Omega-3|
The episode blends clinical authority, empathy, humor, and practical wisdom. Dr. Lake and Dr. Axe move fluidly between technical explanations (lab testing, hormone pathways), vivid analogies (“the body’s not broken, it’s adapting”), and real-world stories (patients, their wives, their own families). They engage with Christian and traditional medicine perspectives but are inclusive, focusing on actionable steps for health and wholeness.
For women feeling worn out, inflamed, or “not themselves,” this episode is a compassionate, practical guide offering clarity, depth, and the promise of genuine healing.