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I'm Dave Asprey. That's Dave spelled D A I V

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E. And this is your 10 minute weekly upgrade on the biggest stories in biohacking, longevity and the world of health.

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Let's go.

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Is the air you're breathing making you sick? Just because you don't see mold doesn't mean it isn't there. My friend Jason Earle has been on a mission for over two decades to help people understand the history of hidden role of indoor air in their health. He's one of the world's leading experts on mold and indoor air quality. And he created the Got Mold Test kit to make professional grade air testing simple and accessible. It uses cutting edge air sampling tech that top inspectors trust. And it's engineered for you at a fraction of the cost. It takes just minutes to get samples using the patented Biovac air sampling pump. Then you send them prepaid to one of the most prestigious microbiology labs in the world. No guesswork, no paperwork and no hidden fees. You get fast results, intuitive reports and great support. And since you keep the pump, you can retest anytime for less. It even comes with a lifetime warranty. Mold may be invisible, but its impact isn't. This kit helps you understand your environment so you can take action for your health. Go to gotmold.com and use code DAVE10 to save 10% and see what's in your air. Because the best biohackers don't guess. They test.

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And Doug, there's nowhere I wouldn't go to help someone customize and save on car insurance with Liberty Mutual. Even if it means sitting front row at a comedy show.

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Hey, everyone.

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Check out this guy and his bird.

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What is this, your first date?

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Oh, no. We help people customize and save on car insurance with Liberty Mutual together. We're married. Me to a human, him to a bird.

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Yeah, the bird looks out of your league. Anyways.

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Only pay for what you need. @liberty mutual.com.

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There's a good chance your cat is

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making you stupid, your protein shake is taking years off your life, and the best stress tool on the planet is blooming outside your front door right now. This week got weird fast, and here's why. So bartonella is a bacterial infection that gets transmitted through cat scratches and bites. And it's been showing up in research on chronic illness a lot more these days. What's changing is the diagnostics. We now have PCR testing that can actually find this thing in the body where older antibody tests kept missing it because the bacteria hides inside red blood cells and vascular tissue. It doesn't behave like a normal infection. It kind of digs in and just stays. I've been talking about stealth pathogens on this show for a long time and this is the classic playbook. Someone gets scratched by their cat or one roaming their neighborhood maybe years ago, and then slowly develops brain fog, mood instability, fatigue, and they spend the next decade getting handed diagnoses that don't quite fit. Depression, anxiety, chronic fatigue. The doctor is pattern matching symptoms and completely missing what's actually driving them. I think Bartonella is dramatically underdiagnosed and the reason is that the standard antibody test misses a significant portion of cases. You need PCR and most conventional doctors won't order it unless you push. If you have a cat, you've been scratched and something in your cognitive or mood picture has never fully resolved, go find a Lyme literate MD and ask specifically for a Bartonella pcr, not a standard tick panel pcr. This is the one that I keep coming back to this week. A Mendelian randomization study which is one of the stronger research designs we have for establishing causation in nutrition short of locking people in a lab for a decade, looked at nearly 270,000 people and found that higher circulating tyrosine is associated with almost a full year of lost lifespan in men, not in women, men specifically. Here's why this matters beyond the headline number, tyrosine is present in a ton of things right now. It's in pre workouts, it's in fat burning formulas and it's loaded into high protein keto diets because meat is full of it. And the reason men get hit and women don't comes down to an enzyme called myeloperoxidase. In men, excess tyrosine gets oxidized into a compound called meta tyrosine which is inflammatory, which drives up the exact markers IL6, CRP, TNF alpha that accelerate aging. Testosterone appears to upregulate that pathway. So the higher your testosterone, the more you might be paying a price for excess tyrosine. If you've been a listener to the show, you now know why. This is such an interesting study. That has certainly got me thinking. For those that may be supplementing with tyrosine or eating a full carnivore diet, it might be wise to go run a panel. Quest and LabCorp both run Plasma tyrosine and phenylalanine. Based on this study you Want your ratio under 10:1. Know your number before you decide. Alright, this one I find pretty remarkable and I want to explain why. Because on the surface tinted contact sounds like a marginal upgrade, and it's not. A company called Altius has developed a tinted contact lens that cuts chromatic aberration by 53% and improves visual contrast by 20 to 30%. Chromatic aberration is the fact that your eye can't focus every wavelength of light to the same point at the same time. Blue light focuses slightly in front of your retina, red light slightly behind it, and your brain is constantly running a background correction process to compensate. That process costs energy. Every hour you're in front of a screen, your brain is burning resources just to make sense of noisy visual input. This is actually something I've been working on for a long time. I created TrueDark glasses specifically because I saw this problem and wanted to solve it. Filtering the light spectrum before it hits your eye so your brain isn't constantly doing damage control. The difference between TrueDark and what most people think of as blue light glasses is the same difference between actually fixing the input and slapping a band aid on it. Most blue light glasses block maybe 15% of the blue spectrum. TrueDark was built to go much further than that because I knew from my own experience that the brain cost of bad light was real and most people had no idea they were paying it. What Altius is doing takes that same logic and moves it to the cornea itself, which is a meaningful step forward. Instead of glasses sitting in front of your eye, the lens is filtering the spectrum at the source. Your retina gets quick information, and your brain does less work. I spent years after my mold exposure dealing with visual processing issues. And I know from personal experience how much cognitive bandwidth gets consumed by corrupted sensory input. When the signal gets cleaner, you get sharper. Not because you got smarter, but because your brain stopped wasting processing power. Esports players are reporting real performance improvements. TBI patients are reporting less overstimulation. This is first principle stuff, and it's the same first principle I was working from when I built TrueDark. If you're not ready for contacts, TrueDark glasses are still a strong starting point. And stack either one with flux or iris on your screens. So this study came out of the University of the Philippines. Real randomized crossover trial, real placebo control. And what they were measuring wasn't energy in the stimulant sense. They were measuring effort, motivation. Specifically whether people would choose harder tasks when the reward was worth it, or whether they just default to the easy path. After four weeks on a combination of Taurine, B6 folate, and B12, people were more willing to exert effort for a reward and showed measurably fewer attention lapses on a validated test. The mechanism is what I want you to pay attention to here. Taurine combined with folate upregulates glutathione in astrocytes, the support cells that keep your neurons running. Better astrocyte function means your prefrontal cortex has more resources to do the thing that most people call willpower. A lot of the people I talk to who describe themselves as unmotivated or stuck are probably just running depleted depleted B vitamins, low taurine, and they're blaming themselves for a nutrient problem. This combination has been kicking around energy drinks for years, but nobody was looking at it mechanistically until now. The data is worth acting on. 2 grams of taurine methylfolate 800 micrograms P5P 50 milligrams methylcobalamin 1 milligram activated forms only in the morning before you eat. Give it four weeks before you judge it.