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Right now, everyone is obsessed with Ozempic and GLP1s because they shut off hunger fast so you can lose weight. But what most people don't know is that your gut already has its own natural Ozempic. And Big Pharma would rather sell you the drug version than remind you that your body has a switch that does the same job. Ozempic only works because it tries to copy that switch. The drug forces a signal to your brain that says, we're full. Stop eating. But your gut can send that signal on its own without a needle, without a prescription, without a bill, and without a lot of side effects. When your natural switch is active, appetite drops on its own, cravings quiet down, and visceral fat stores start burning away the way they're supposed to. And today, I'm going to show you exactly how this natural switch works, why it shuts down in so many people, and how to turn it on using simple tools to restore the system that Ozempic is trying to hijack. And yes, this is classical biohacking knowledge from the guy who created the biohacking movement. Part 1. Hunger is not a math problem. It's a hormone problem. Before we talk about the fix, we need to talk about the mistake almost everyone makes. See, most people think the secret to weight loss is eating less or counting calories. In my Quest to lose £100, I found out that does not work, as has every person who's ever tried to lose weight sustainably that way. And trust me, calories in, calories out is one of the biggest myths in the medical field. And they've been telling us this is how to lose weight. It's not. The system wants you to think that your body is a simple calculator. If you eat fewer calories than you burn, the fat should just melt away. This is why the diet apps track every bite, why meal plans obsess over numbers, why you feel guilty every time you go over your limit, even though you don't really even know how many calories are in that cookie. It's just a guess. When you overeat, you blame yourself for not having enough discipline. You start to think hunger is a mindset problem, something you should be able to out think or outwork if you just try harder. This was my life for years. When I weighed 300 pounds, I went to the gym 90 minutes a day, six days a week. I was constantly starving. So hungry I feel that gnawing feeling. It just doesn't work. And a few people lose weight for a short period of time. And then it comes bouncing back just like it did for me, over and over. Because in the calories, in calories, out story, quantity matters more than biology. So you keep tightening the rules and hoping the math is finally going to work. Newsflash. It's not that you're not doing it, it's that it doesn't work. But visceral fat, the hidden fat that builds up deep inside your organs, that's actually a hormone problem rooted in the brain's miscommunication with the gut. And visceral fat is the most dangerous kind of fat. I have low levels of visceral fat for an 18 year old, and the calendar thinks I'm slightly over 50. My lab test would tell you I'm younger. Your brain does not stare at a calorie chart after you eat. It listens to chemical signals that come from your gut, your fat tissue, and from your blood. One of the most important messages is the I'm full signal. That signal depends on hormones your gut is supposed to release after a meal, but not if you don't know how to eat. When those signals are weak, your brain never really hears that the meal is over. So you finish your plate and you're still unsatisfied. So you just keep going. And on the other side, there are hunger hormones, especially one called ghrelin. They stay high even after large meals. So your body keeps pushing you towards food even when logic says you've had enough. As a result, your brain and your body want different things. Your logical mind is counting calories and saying, I should stop. But your biology is screaming, I'm still hungry. And your biology will win, because as you cut calories harder, your body senses danger. It thinks you're entering starvation, so it slows down your metabolism to conserve energy. And then you get fat on less calories. You burn fewer calories at rest. You feel colder, more tired, and more obsessed with food. And the harder you try to eat less, the louder the hunger signals become. You will not win. Over time, dieting turns into a constant war between what you know and what your body feels. And most people eventually lose that fight because hormones always win over willpower. So your gut's not just a tube that digests food. It's an endocrine organ. These types of organs secrete hormones directly into your bloodstream. They control bodily functions like growth and metabolism and fertility. Your gut releases hormones that control hunger and fullness, or satiety. One of the most important of those is GLP1. When you eat specific cells in your intestine are supposed to release GLP1 into your bloodstream. That hormone tells your brain food is here, you can slow down. It helps your pancreas release insulin in a healthy way. It slows stomach emptying just enough so you feel satisfied, not stuffed. When your body releases GLP1 correctly, cravings drop. Your energy feels more stable. Your meals naturally come to an end without a flavor fight. And when your gut doesn't release GLP1 the way it's supposed to, hunger hormones dominate and your whole system leans towards storing fat instead of burning it. This is why two people can eat the same calories and get very different results. One has a gut that speaks clearly to the brain. The other has a gut whose voice has gotten quiet. So sustainable weight loss requires reactivating natural satiety hormones instead of constantly using your willpower to fight hunger and then lose. The goal is not to live the rest of your life on strict calorie restriction and feel miserable every day. The goal is to fix the signal so you can naturally eat less and you're not going to feel like you're at war with yourself anymore. When GLP1 levels rise naturally, your meals start to become self limiting. You feel satisfied sooner and you don't feel the same pull to keep going and you don't want to snack afterwards. Your energy stays steady instead of crashing in the afternoon. Cravings and emotional eating just fade away because your body actually feels nourished. This means you need to shift from how little can I eat? To how do I get my hormones working for me again? The first step is to stop pure willpower. Dieting for the next 30 days, or maybe for the rest of your life doesn't mean you want to overeat on purpose. It means you stop slashing calories to extremes and you stop punishing yourself with tiny portions. Give your body a break from starvation signals so your metabolism can stay. Stop defending every pound. Next, switch from all day grazing to structured meals. Aim for two or three real meals a day with clear gaps in between. When you snack constantly, your hormones never get a full cycle. When you eat distinct meals, your gut can send clear waves of hunger and fullness. Instead of a constant blur of maybe I should eat something else at each meal. Make sure you eat enough protein and fiber so your gut hormones will get rid of least. Protein gives your body building blocks and increases satiety. Fiber slows digestion and provides raw material for your gut to make signaling molecules. To start listening to hormones instead of just numbers. You pause before and after each meal and Ask one simple am I physically hungry or is this habit or emotion? Physical hunger builds slowly. It often shows up like an empty or gnawing feeling inside your stomach, but it's gentle and it's not tied to a specific food. Emotional hunger and cravings feel urgent. They appear suddenly, and usually you want a very specific comfort food. You don't need to judge the answer, you just need to notice it and be aware. Over time. That trains you to see when your hormones are driving the bus and when old patterns are taking over. I had to deal with both. Most people don't understand this part. For me, I had to fast for four days in a cave all by myself to figure out what was emotional and what was actual hunger. They're very different, but most of us have them blended together. As you're starting this process, begin to identify the things in your day that are killing your GLP one Response Liquid sugar, frequent snacking, ultra processed foods, and eating late at night will weaken your I am full messaging. You don't have to remove these things all at once, but you do want to mark them as suspects because something you're doing is causing you to be hungry when you shouldn't be. So for the next week, just notice when they show up. Once you see the pattern, it becomes much easier to Change it. Part 2 why synthetic GLP1 ozempic often backfires but when people finally hear about GLP1 and understand how important it is, they usually don't fix the system that makes it. They just inject the signal. Instead, they resort to drugs like Ozempic that artificially try to mimic something that's a natural part of weight loss. When someone feels out of control around food, the idea of a simple injection that shuts hunger off sounds like a miracle. And it can be. There's nothing wrong with using Ozempic under doctor's care if you take care of all the other side effects. It's just that you may not have to because of this video. Ozempic works by pretending to be GLP1, the same hormone your gut is supposed to release after you eat it. It slows stomach emptying, so food sits there longer. It makes the brain feel full, faster, and for a much longer time. Appetite drops sharply, calorie intake plummets without effort, and the number on the scale finally starts to fall. From the outside, it looks like magic. It's a fix everyone's been waiting for. But the mechanism is pharmacological, not physiological. Ozempic doesn't repair your natural appetite system, it just Overrides it. Instead of helping your gut produce real GLP1, the drugs force the signal in from the outside. Your pancreas, your gut and your brain start depending on the artificial message to manage hunger and blood sugar. That said, GLP1s can be miracle drugs for longevity. You should just do it the natural way first. Over time, the gut brain loop becomes quieter because the drug is doing the talking for it. The body adapts to the injection instead of rebuilding its own natural rhythms. And this creates a false sense of stability that only lasts as long as the drug is in your system. This becomes a problem the moment you stop. And as the artificial signal fades, appetite doesn't just return to normal, it rebounds hard. Just like if you overcut calories, your brain, which has been held back for months, is going to overcorrect. Hunger surges, cravings spike, and the calm relationship with food that the drug created collapses overnight. Many people regain the weight they lost, and a large number even overshoot it because months of injections suppress their appetite hormones. The body tries to protect itself from what it believes was a starvation period. And it stores fat more aggressively than before. The same thing happens if you practice starvation, dieting and over exercising. You lose weight and then you gain more. So artificially forcing GLP1 signaling may not build the metabolic stability your body actually needs. GLP1 drugs like ozempic can reduce appetite, but they don't heal the system that controls appetite. That's your job. And that's why long term use of these drugs often comes with nausea, fatigue, digestive discomfort, and slowed digestion. That just doesn't feel natural. If I could have used GLP ones when I weighed 300 pounds, I would have. And there's no reason that you couldn't do it. But I never got sustainable weight loss until I learned when I'm sharing this video about controlling my natural hunger hormones. Some people even lose muscle along with fat when they use GLP1s, which lowers your metabolic rate and makes future weight loss even harder. And your hormone imbalance starts relying on the injection instead of your own biology. And that muscle loss is why people develop a zynpic phase and which is a sunken, aged look caused by fast loss of facial fat and the underlying muscles. But you don't need Ozempic in the first place because your body already has its own built in ozempic system and it activates through what you feed your gut. Your microbiome is a vast community of trillions of microorganisms that live in your gut. And certain Gut microbes produce short chain fatty acids that talk directly to your brain and metabolism. And one of the strongest of those molecules is called butyrate. Your gut bacteria make butyrate when you feed them the right kind of carbs. Butyrate is powerful because it directly stimulates the cells in your intestine that release GLP1. And when those cells detect butyrate, they open the valve and release natural GLP1 into your bloodstream. That's how your gut is supposed to tell your brain that the meal is over. And to understand how this works, you need to understand resistant starch. Resistant starch is a special form of carbohydrate that resists digestion in your small intestine. It moves through your system intact until it reaches your colon. And that's where the magic happens. If you have them, your gut bacteria grab onto this resistant starch and they use it as fuel. They ferment it slowly and it turns into butyrate. And that butyrate then signals your intestinal L cells to release GLP1, the same hormone Ozempic tries to mimic. And the result is smoother blood sugar control, a quieter appetite, and a natural stopping point. At meals, you feel full without forcing yourself to be full. You eat less because your biology says that was enough. Now this is interesting. You can take resistant starch, you could eat more foods with resistant starch, or you could actually take butyrate itself as a supplement. And my favorite brand is linked in the bio. And as a side effect, butyrate also raises ketones in your body. So if you're on a low carb diet, it could actually help you. Well, this pathway from resistant starch to to butyrate to GLP1 is the hidden pathway that drug companies copied. Ozempic forces GLP1 in from the outside, and resistant starch triggers GLP1 from the inside. One overrides your system, the other restores it. That's why eating foods rich in resistant starch helps your gut produce its own GLP1, which turns on your natural appetite regulation. When resistant starch and butyrate are high, your hunger goes down, especially between meals and when most of us struggle. I don't think about food for at least four hours after meal because I fix the system in myself. And I used to weigh 300 pounds and eat eight times a day. I eat twice a day now. Cravings start to fade because your blood sugar stays stable. When you do this, you don't get the crashes after sugary or an ultra processed meal, you stop Thinking about food all day because your gut finally has the raw materials it needed to send a clear message to your brain that says, basically, don't think about food now, you don't need it. Your microbiome also can grow more diverse. Your inflammation drops and metabolism becomes way more predictable. This is how you unlock the same patho drugs like a zimpic use, but directly from real food. In my own experiments in my longevity book, by using resistant starch, I quadrupled the amount of gut bacteria and the number of species of gut bacteria, including the ones that grow butyrate. So you can change your bacteria, which changes your biology. And if you want your body to naturally produce its own GLP1 without wrecking your muscles, like ozempic does, all you have to do is feed the gut in a way that keeps inflammation low and keeps mitochondrial signaling high. The problem is that most people dump resistant starch foods like cooled potatoes, rice, oats and beans into the body, thinking they're helping, when in reality they're just creating inflammation and mitochondrial stress. So instead of turning on your natural ozempic pathway the way you want it, you end up bloated, tired, more insulin resistant, and probably farting a lot. Instead of those high toxin foods, you could use clean sources like green banana flour, acacia gum, tiger nut flour, or a small amount of raw potato starch. Those provide resistant starch without triggering inflammation. And along these, you can add prebiotic vegetables like small amounts of onions, garlic, or asparagus, because a healthy gut microbiome can't thrive on starch alone. But too much onion or garlic can cause problems as well. Your gut needs real fibers that feed beneficial bacteria without irritating the gut lining. And then you support all this by eating the right fats, which include grass fed butter that contains butyrate already naturally, or ghee or MCT oil, Because they stabilize your blood sugar, they lower inflammation, and they create the mitochondrial energy that your body needs for proper metabolic signaling. And instead of overwhelming your gut all at once, you just increase slowly and you start with tiny doses for that first week and gradually increase it once your body is ready. Because no one wants to fart that much, go slow. In week one, you introduce one resistant starch food per day in a small portion. In weeks two or three, you can increase to two meals per day that contain that resistant starch. By week four and beyond, you adjust based on how your body responds. If you get bloating or gas, it's not a signal to keep going. It's a signal your gut lining is irritated. You have too much fermentation and you need to slow down. You're retraining your gut bacteria to have the right bacteria present. But even the best resistant starch strategy is going to fail when your gut becomes too damaged to respond. You can eat all the resistant starch you want, but if the ecosystem inside your gut's disturbed, the bacteria that create butyrate can't thrive. They can't ferment resistant starch. That means that the butyrate can't send GLP1 signals to your brain because it's not there. And instead of feeling calm and satisfied after meals, you just feel hungry and as exhausted as you did before. This is the piece that most people overlook. They think they're doing everything right. But the inner environment is still too inflamed or too depleted or too stressed to activate the chemistry that controls appetite. And the modern world quietly destroys that environment long before you ever notice symptoms. Processed foods, sugar, glyphosate, industrial seed oils. They feed the wrong microbes and they starve the ones that produce butyrate. Artificial sweeteners confuse gut bacteria and interfere with the way they process energy. Chronic stress makes your gut lining way more permeable, which means tiny gaps open up in your intestines, and that lets things leak into your bloodstream. And your body doesn't need that in your blood. Those are called lipopolysaccharide toxins, and they cause brain fog and cravings. Chronic stress also sends danger signals throughout your body and and it disrupts the hormonal loop between your gut and your brain. When you don't sleep well, it throws off your circadian rhythm. And that rhythm is your body's 24 hour internal clock. It tells every system, including your sleep system, your hormones, your energy and your digestion when to turn on and off. And your digestion works best when it follows the circadian clock, which is why your gut breaks down food effectively and efficiently during the day. But it doesn't do a good job at night. And antibiotics, even just a few rounds, can wipe out entire colonies of those microbes that you need in your gut. And when you drink a lot, it weakens your gut lining and reduces the microbial diversity that you need in order to have all this energy. And day after day of diets that lack resistant starch and constant snacking can prevent your gut from ever entering true repair mode. And when all those forces combine, the consequences are predictable. You look like I used to look. You'll weigh 300 pounds. You'll be tired all the time your beneficial bacteria die off, the butyrate producing microbes that control your natural GLP1 release shrink or just go away entirely. Inflammation rises and begins to block the receptors that GLP1 needs to work. Resistant starch enters the gut, but nothing useful happens because the microbes that were supposed to transform it are no longer present. It's like trying to run a factory with no workers and no robots. The raw material arrives, but the system that turns it into something valuable is missing. Until you rebuild that environment, the natural ozempic pathway can't wake up. So if you want to fully activate your natural GLP1 system, you've got to first rebuild the gut environment that makes it possible. You don't fix your gut by dumping in random superfoods. You fix it by feeding the right microbes, starving the wrong ones, and removing the toxins that damage your gut lining in the first place. You start by repopulating beneficial bacteria with low toxin fiber rich foods. In addition, you can take specific probiotics that actually work and specific prebiotics. And I've got links in the bio so you can tell the ones that actually work. There's also a supplement called GLPerfect that's specifically designed to help your body make more of its own GLP1. Ultra processed foods, seed oils, artificial sweeteners, fried foods, and anything laced with industrial additives. These all punch holes in your gut lining and distort the signals your gut sends to your brain. Unfortunately, that includes wheat from the United States because it's full of glyphosate that is well documented to damage your gut bacteria. So follow one simple rule. If a food didn't exist 100 years ago, it probably shouldn't be an everyday staple. And that instantly removes most of what harms your gut without needing detailed tracking. You don't need an app to tell you that Pop tarts aren't really good for you. Once you're eating the right stuff and you've taken the wrong stuff out of your diet, you want to support the communication between your gut and your brain. And that means you want to reduce your stress. If you allow yourself to be stressed all the time, even emotional stress or circadian stress, well, your gut's going to get old. Your gut won't work well, and you'll have more stress signaling and less of this GLP1 signaling. So you could do five minutes of slow breathing every day. You could keep your sleep schedule consistent because your digestive hormones follow a circadian pattern. Move your body gently by going for A walk after a meal and just five or 10 minutes of walking can totally change your gut motility and reduce blood sugar spikes. These are small adjustments and they create an internal rhythm that your gut relies on. And the next thing is kind of hard to do, but also kind of easy to do. You've got to adjust your meal timing to create a repair window. Don't eat all day long. Eat two or three main meals and make sure that your final meal of the day is at least 33 hours before bedtime so your gut can do its job before you go to sleep. That means you can create a 12 to 14 hour overnight fasting window so your gut lining can repair itself and inflammatory signals can calm down. And if 12 to 14 hours seems like a lot, you've probably slept for eight hours. And if you didn't eat three hours before bed, you got 11 hours. Have breakfast. An hour or two later, you got your 14 hours. It's not that hard. You're not going to starve. That simple structure gives your microbiome the time it needs to rebuild. Hydration is also really important. Drink water when you feel thirsty so your gut stays hydrated during digestion. And put a pinch of salt or some electrolytes in it so you're even more hydrated. And when you're drinking water, add electrolytes like sodium, potassium and magnesium if you feel dehydrated or just tired. My favorite brand is Element. Get the discount code@drinkelement.com Dave and avoid drinking large amounts right before you go to bed so nothing interrupts your sleep. If you really want to control your stress response and get better sleep so your gut can heal, wear the nighttime truedark glasses. I invented these about 10 years ago because nothing else actually blocks all of the wavelengths that shut off melatonin and wreck your hormone timing. It's not about blocking blue light. These have five optical filters in them that change many different light variables so that your body knows it's nighttime and your digestion can go into repair mode. It's one of the easiest ways to protect deep, deep sleep cycles. And we even published a study in a medical journal showing that TrueDark lenses shift your brain waves towards calm in about 15 minutes. Get your pair@truedark.com, use code DAVETUBE for my discount. As your gut starts to heal, resistant starch becomes more effective. That's because the microbes that fermented into butyrate can finally be active. And when they're active, they actually do what they're supposed to do. That's when your appetite control starts to just feel natural. It's when the switch begins to turn back on, and it's how you lose weight naturally and you don't have to end up with an Ozempic face. Subscribe to my email to get updated information on GLP1, including the safe protocols for using it if you need to, and to get all the other biohacking tips@daveasprey.com.