Podcast Summary: The Isabel Brown Show

Episode: We Need MORE Babies – Not Lab-Designed Ones. Nucleus Genomics Exposed

Date: November 24, 2025
Host: Isabel Brown (Daily Wire)

Episode Overview

In this episode, Isabel Brown critically examines emerging trends in fertility technology—specifically the rise of companies like Nucleus Genomics, which advertise “designer babies” and advanced embryo selection via platforms like PickYourBaby.com. While championing the pro-family message and expressing concern over America’s declining birthrates, Isabel debates the ethics of using genetic technology in family planning, cautioning against the commodification and eugenic overtones of such practices. She also reflects on her recent Wall Street Journal feature, the challenges and beauty of traditional family life, and society’s crossroads between reviving versus redefining family.

Key Discussion Points & Insights

1. Isabel’s Recent Personal & Media Milestones (01:21–04:30)

• Isabel shares excitement about being on the Wall Street Journal front page and recently meeting the President.
• Emphasizes her public advocacy for prioritizing family and encouraging young women to have children, pushing back against modern trends of delayed or absent motherhood.

2. The Rise of Nucleus Genomics and “Designer Babies” (04:30–18:50)

a. Discovery of PickYourBaby.com and NYC Subway Ads

• Isabel is disturbed by Nucleus Genomics' "Have Your Best Baby" campaign, highlighting targeted subway ads in NYC for “IVF Plus” and embryo selection.
• She describes the company’s pitch: "Anyone can have a taller, smarter and healthier baby with IVF Plus."
  • “What’s wrong with short people?... Justice for the short people." (Isabel, 05:12)
• Points out the eerie similarity to eugenics, where desirable traits such as height, IQ, and health risks are selectable.

b. Exploring the PickYourBaby.com Website On-Air

• Isabel walks through the site, noting its unsettling resemblance to an online shopping experience, featuring multiethnic babies and customizable options.
• The site promises “your baby's first preview” by combining parental DNA via cheek swabs before pregnancy.
• Isabel’s reaction:
  • "Does this not look like shopping for a baby? This is so weird." (12:13)
• Concerns raised about privacy and potential misuse:
  • "Who's to say they won't take your DNA and attempt to alter it in some way or edit it? I hate this. This is—no, no, no." (13:14)

c. How the Technology Functions: From Preview to Embryo Selection

• The company offers a "high-tech punnett square" predicting outcomes like eye color, hair color, IQ (which Isabel notes science does not firmly link to genetics), and autism risk.
• Isabel is skeptical about screening for autism:
  • "I'm sorry, I thought we didn’t know what causes autism… Now it’s totally fine to say that at your favorite store you can go shopping to find your ideal baby." (16:01)

3. The Dystopian Reality of Genetic Commodification (22:50–32:30)

a. Comparing and Ranking Embryos

• Isabel details how the site allows parents to compare embryos by sex, eye color, health risks, and IQ, ranking children as data points.
  • “They’ve been reduced to a chart on the internet. ... Like walking into the American Girl doll store... Disgusting." (27:40)
• She forcefully connects these practices to historical eugenics, referencing 20th-century atrocities and warning that “this is literally what the Nazis practiced and learned from us.”

b. Filtering Children by Traits

• Isabel demonstrates filtering embryos by a desired trait (like breast cancer risk), which instantly reshuffles the ranking:
  • "If the most important thing to me is that my kid has the lowest possible risk of breast cancer... It automatically reshuffles everything to say, Embryo 5 is your ideal choice here." (29:50)
• Argues this approach strips dignity from human life, transforming future children into consumer products.

4. The Founder and Investor Agenda Behind Nucleus Genomics (32:30–37:20)

• Brief background on Keon Sadeghi, Nucleus Genomics’ 25-year-old founder (Ivy League dropout, $30+ million in funding).
• Tech investors envision genetic matchmaking on dating apps—potentially simulating baby gene-reports from would-be couples’ DNA:
  • “No to kid simulations on our dating apps.” (34:41)
• Isabel suspects DNA data could be sold to third parties, calling this both dystopian and a gross violation of privacy.

5. The Flawed Compassion of “Screening Out” Imperfect Babies (37:20–43:35)

• Isabel reads from Sadeghi’s Reddit AMA, where he motivates his work via a family tragedy (his 16-year-old cousin dying of a genetic disease), saying everyone “deserves actionable, life-saving insights into their DNA.”
• Isabel sharply critiques this, noting that the real-world effect is denying life to babies who don’t fit genetic ideals:
  • "Because of a genetic disease that your 16-year-old cousin died for in her sleep… the answer is… that baby… to never have been born in the first place." (40:48)
• “That’s our solution? That’s our compassion? ...This is what we call modern family planning. ...It is straight up eugenics.” (41:56)

6. Societal Crossroads: Revive or Redefine the Family? (43:35–48:35)

• Isabel discusses her Wall Street Journal feature, which highlights a generational divide:
  • 75% of liberal women ages 18–35 are childless vs. 40% of conservatives (45:10)
  • "Conservatives: having kids is very much still a part of what it means to be a whole person."
• She draws a line between declining birth rates and the dangers of “over-correcting” by treating children as consumer products:
  • “The anti-family state of affairs in America as they so beautifully articulate ... also includes reducing your children to data points, to a chart.” (47:11)
• Argues instead for love, natural family formation, and accepting imperfections:
  • “Love is not based on percentage points. Love is not based on charts… Love is based in commitment.” (48:13)
  • “The answer... is not just to blindly make more babies... But we cannot commodify human beings in the process.” (48:56)

Notable Quotes & Memorable Moments

• On eugenics and embryo selection:
  "This is literally just eugenics. This is literally what the Nazis practiced and learned from us." (27:59)
• On love and family:
  "Love is not based on percentage points. Love is not based on charts. Love is not based on probability. Love is based in commitment." (48:13)
• On society's direction:
  "We have to be better than this in a society that we are truly proud to call home. ...Because this, the Giver Gattaca 1984 Brave New World vibes is just not gonna be it for me." (49:55)
• Isabel signs off wishing listeners a happy Thanksgiving, encouraging them to disconnect, enjoy family, and be present.

Key Timestamps

• 01:21–04:30: Isabel’s Wall Street Journal feature, pro-family message
• 04:30–18:50: Introduction to Nucleus Genomics, PickYourBaby.com, and her walkthrough of their website
• 22:50–32:30: Analysis and critique of genetic embryo selection features
• 32:30–37:20: Nucleus Genomics founder background, big tech’s role, and data concerns
• 37:20–43:35: Reddit AMA excerpt, critique of eugenics logic
• 43:35–48:35: Societal implications, Wall Street Journal feature discussion
• 48:35–End: Final reflections, call to cherish non-commodified family life

Tone & Closing Thoughts

Isabel’s tone is passionate, humorous at times (bantering with her baby), and deeply concerned about the moral implications of new genetic technologies. She is firm in opposing the commodification of human life, combining pro-family conservatism with warnings about technological overreach. The episode urges listeners toward gratitude, authentic community, and resisting trends that turn children and love into data-driven products.

For those who didn't listen:
This episode is a timely, spirited exposé of the alarming future being shaped by high-tech genetic “family planning,” juxtaposed with a personal call to cherish traditional family and the humanity of every child, flaws and all.