Trump's Surgeon General Pick OUT, Anti-ICE Protest Assault, Meat-Alzheimer's Study: AM Update 5/1

Summary

---

The Megyn Kelly Show — AM Update 5/1/26

Host: Megyn Kelly
Air Date: May 1, 2026
Theme: A rapid-fire roundup of political, legal, and cultural headlines, including the fallout from Trump’s withdrawn Surgeon General pick, a progressive shake-up in Maine’s Senate race, an assault against a conservative reporter at an anti-ICE protest, and research on the links between meat consumption and Alzheimer’s for those with specific genetic risks.

---

Main Topics Overview

In this AM Update, Megyn Kelly breaks down several pressing news stories:

• President Trump pulling his Surgeon General nominee, Dr. Casey Means, after GOP resistance.
• Major developments in the Maine Senate race, with Governor Janet Mills bowing out and the rise of progressive Graham Platner.
• Details on an assault against conservative reporter Savannah Hernandez at an anti-ICE protest in Minneapolis.
• New research from Sweden suggesting certain genetic profiles may benefit cognitively from higher meat consumption.

---

Key Discussion Points & Insights

1. Trump Withdraws Surgeon General Nominee Casey Means

[02:28 - 08:42]

• Nomination Stalled:
  President Trump withdrew Dr. Casey Means’ nomination for U.S. Surgeon General after opposition from GOP Senator Bill Cassidy, a physician, due to Means’ vaccine positions.
• Senate Hearing Exchange:
  • Sen. Cassidy: “Do you believe that vaccines, whether individually or collectively, contribute to autism?”
    [02:58]
  • Dr. Means: “We do not know as a medical community what causes autism. … We should not leave any stones unturned.”
    [03:04]
  • Dr. Means: “I do accept that evidence. I also think that science is never settled.”
    [03:38]
• Political Fallout:
  Trump’s social media posts blamed Cassidy for stalling the ‘MAHA’ movement (Make America Healthy Again), and encouraged Louisiana voters to oppose Cassidy:

  “Hopefully all of the great Republican people of Louisiana, which I won big three times, will be voting Bill Cassidy out of office…” [03:42]

• Means and Allies Respond:
  • Dr. Means: “I genuinely believe in my heart that the Trump administration is trying to figure out how to move the balls forward. Yes, there are some setbacks, but there are some huge wins.” [04:44]
  • RFK Jr. (HHS Secretary): “By sabotaging this appointment, Bill Cassidy once again did the dirty work for entrenched interests seeking to stall the Maha movement and protect the very status quo that has made America the sickest nation on earth.” [04:44]
• Replacement Nominee:
  Trump nominates Dr. Nicole Saphier, Fox News contributor, who shares some of Means’ parental vaccine discretion views. No confirmation hearing date set.

2. Progressive Upset in Maine’s Senate Race

[08:42 - 11:34]

• Governor Janet Mills Exits:
  Mills steps out of the Democrat Senate primary, citing lack of financial resources despite national endorsements.

  "I very simply do not have the one thing that political campaigns unfortunately require today, the financial resources." [08:42]

• Rise of Graham Platner:
  Progressive Graham Platner surges, backed by Bernie Sanders and Elizabeth Warren, and raises significantly more funds in recent quarters.
  • Platner to supporters:

    “We're going to show the rest of the country that this is the politics of the future and that working people can organize and they can win.” [08:42]

• Controversies:
  • Nazi-linked Tattoo: Platner admits on Pod Save America to an old Marine Corps tattoo linked to Nazi imagery, claims ignorance of the emblem’s history at the time. [09:10]
  • Reddit Comments: Past online comments include racial stereotypes, leftist rhetoric, and disillusionment with U.S. politics.

    • “Why don't black people tip? I work as a bartender and it always amazes me how solid the stereotype is… I did used to love America, or at least the idea of it. These days I'm pretty disgusted by it all.” [10:03]

  • Platner’s Response:

    “I was… effing around on the Internet at a time when I felt lost and very disillusioned with our government… Of course I’m not a socialist. I'm a small business owner, a Marine Corps veteran and and a retired shitposter.” [10:23]

• Platform:
  Open to court-packing, impeachments, aggressive Senate investigations. [10:23]
• Polling:
  Platner leads against incumbent GOP Senator Susan Collins by 7.6 points (RealClearPolitics average). [11:34]
• Senator Collins on Mills’ withdrawal:

  “I'm sure this was a very difficult decision for Governor Mills and I wish her well. She has devoted her life to public service in the state of Maine.” [11:06]

3. Turning Point USA Reporter Assaulted at Anti-ICE Protest

[13:05 - 16:47]

• Incident:
  Reporter Savannah Hernandez assaulted by three members of the Ostrushko family during an anti-ICE protest at the Whipple Federal Building in Minneapolis on April 11. [13:05]
• Indictments:
  • Christopher and daughter Paige charged with interference and assault.
  • Mother Diana charged with assault.
• Footage:
  Hernandez is surrounded, physically blocked, shoved, and ultimately thrown to the ground.
  • Hernandez: “Get away from me. Stop touching me.” [14:10]
• Defendants’ Defense:
  On a podcast, Christopher claims he acted to protect his family.

  • “You said it and I, that's what I believe. I just wanted her to leave so that this whole thing would stop.” [15:33]

• Legal Response:
  Acting Attorney General:

  “These deplorable actions, as charged in the indictment, will not be tolerated in America… this Department of Justice will always punish unhinged acts of political violence.” [15:45]

• Hernandez’s Reaction:

  “I am incredibly grateful that both the FBI and DOJ have prioritized this and have brought these charges swiftly… this sets a very strong precedent and sends a very strong message to the left wing that under this FBI, they're not going to be able to attack people anymore.” [16:13]

4. Meat and Alzheimer’s: New Study Links Consumption and Genetic Risk

[16:47 - 21:51]

• Research Recap:
  Swedish study finds APOE4 gene carriers, who are at higher genetic risk of Alzheimer’s, showed lower dementia risk when regularly eating unprocessed meat (e.g., beef), compared to those who eat less or no meat. [16:47]
  • Dr. Jacob Norgrian:

    “If you have the APOE4 gene, your Alzheimer's risk is higher… these risk genotypes make up approximately a quarter of the population, but they account for the majority of Alzheimer's cases.” [17:38]

  • Examples: Gwyneth Paltrow (APOE4 carrier), Chris Hemsworth (two copies).
• Potential Mechanisms:
  • Higher cholesterol and brain plaque in APOE4 carriers.
  • Meat may supply key nutrients (B12, iron, zinc) that aid brain health specifically for this group.
• Broader Implications for Nutrition:
  • Dr. Sarah Garcia Tachik:

    “Brain health needs to be considered when we're writing dietary guidelines… If we can replicate this across cohorts… this would open the door for precision nutrition or recommendations tailored to people's genotype.” [20:28]

• Genetic Testing:
  Blood or cheek swab tests can reveal APOE status but not commonly done outside of dementia workups. [21:28]
• Takeaway:
  Kelly notes the science could eventually reshape dietary guidelines to be more personalized rather than one-size-fits-all.

---

Notable Quotes & Memorable Moments

| Timestamp | Speaker | Quote or Moment | |------------|------------------------|-----------------------------------------------------------------------------------------------------------------------------------| | 03:38 | Dr. Casey Means | "I do accept that evidence. I also think that science is never settled." | | 04:44 | Dr. Casey Means | “There are some setbacks, but there are some huge wins. And the way that culture has moved forward in the past year is monumental.”| | 08:42 | Graham Platner | "We're going to show the rest of the country that this is the politics of the future and that working people can organize and they can win."| | 10:03 | Graham Platner (AI) | "Why don't black people tip?... I did used to love America, or at least the idea of it. These days I'm pretty disgusted by it all."| | 10:23 | Graham Platner | "I'm a small business owner, a Marine Corps veteran and and a retired shitposter." | | 11:06 | Sen. Susan Collins | "I'm sure this was a very difficult decision for Governor Mills and I wish her well. She has devoted her life to public service in the state of Maine."| | 14:10 | Savannah Hernandez | "Get away from me. Stop touching me." | | 15:33 | Christopher Ostrushko | "I just wanted her to leave so that this whole thing would stop." | | 15:45 | AG Todd Blanche | "These deplorable actions, as charged in the indictment, will not be tolerated in America… this Department of Justice will always punish unhinged acts of political violence."| | 16:13 | Savannah Hernandez | “I am incredibly grateful that both the FBI and DOJ have prioritized this and have brought these charges swiftly... this sets a very strong precedent and sends a very strong message to the left wing...”| | 17:38 | Dr. Jacob Norgrian | "If you have the APOE4 gene, your Alzheimer's risk is higher... these risk genotypes make up approximately a quarter of the population, but they account for the majority of Alzheimer's cases."| | 20:28 | Dr. Sarah Garcia Tachik| "We need to do more research on the cognitive effects of diet and in particularly, look at this effect of APOE... this would open the door for... recommendations that are tailored to people's genotype."|

---

Key Timestamps for Segments

• [02:28] Trump’s Surgeon General pick withdrawn; Hill opposition, hearing highlights
• [04:44] Social media responses; nomination process outlook
• [08:42] Maine Senate primary shakeup: Mills out, Platner surges
• [09:10] Platner controversies: tattoo, social media history
• [11:06] Sen. Susan Collins on the shakeup
• [13:05] Savannah Hernandez assailed at anti-ICE protest; charges, reactions
• [16:47] Swedish study: meat, genetics, and Alzheimer's explained

---

Engaging Takeaways

• The politics of health in the US remain deeply contested, with vaccine debates and the “MAHA” movement influencing top appointments.
• Progressive economic populism is upending Democratic primaries, even in moderate-leaning states like Maine, though not without scandals.
• Assaults on journalists continue to draw national attention and DOJ action—highlighting the ongoing battle over political violence and free speech.
• Rapidly evolving science could soon make personalized nutrition the norm, upending decades of one-size-fits-all health advice—especially for those at genetic risk for dementia.

---

Transcript

[VRBO Advertiser]

Early birds always rise to the occasion for summer vacation planning because early gets you closer to the action. So don't be late. Book your next vacation early on VRBO and save over $120. Rise and shine. Average savings $141. Select homes only.

[Megyn Kelly]

Good morning, everyone. I'm Megyn Kelly. It's May Friday, May 1st to be exact, and this is your AM update. Trump withdraws his Surgeon General nominee, Dr. Casey Means out after facing resistance from one GOP senator.

[Graham Platner]

We're gonna make this happen and we're gonna show the rest of the country that this is the politics of the future.

[Megyn Kelly]

Governor Janet Mills dropping out of the Maine Democrat Senate primary, clearing the field for a surging progressive challenger to take on GOP Senator Susan Collins in the general election.

[Savannah Hernandez]

Get away.

No, keep the upcoming Stop touching me.

[Megyn Kelly]

Three members of the same family now facing federal charges accused of assaulting a Turning Point USA reporter, an anti ice protest and new research suggests eating more meat could lower your risk of developing Alzheimer's if you carry a specific genealogy. All that and more coming up in just a moment on your AM Update.

[PureTalk Advertiser]

Paying 70, 80, 90 bucks a month to Big Wireless for unlimited data is insane. Especially when PureTalk is going to give you unlimited high speed data for just 34.99amonth. Unlimited high speed data at PureTalk used to start at 55 bucks a month, but because Pure Talk is constantly pushing to give you more for less, you can now get unlimited high speed data

[Megyn Kelly]

for just under $35. So if you have looked at Pure

[PureTalk Advertiser]

Talk before and did not make the move, check again. Okay. If you are wondering, is Pure Talks

[Megyn Kelly]

network really as good as the other

[PureTalk Advertiser]

overpriced Big guys, try it for 30 days with no contract, no cancellation fees,

[Megyn Kelly]

you have nothing to lose.

[PureTalk Advertiser]

Their US Customer service team is standing by to help you switch in as little as 10 minutes. Just dial £250 and say Megan Kelly to claim Claim unlimited high speed data for just 34.99. Again, dial £250 and say Megan Kelly to switch to America's wireless company Pure Talk. Try it out.

[Megyn Kelly]

President Trump yesterday pulling his nomination of Dr. Casey means as Surgeon General means his nomination stalling on the Hill amid opposition from some, including one senator in particular skeptical of her views on vaccines, which align closely with those of HHS Secretary rfkj. Here, an exchange from KC Means's February confirmation hearing with that Senator Bill Cassidy of Louisiana, a Republican and medical doctor.

[Senator Bill Cassidy]

Do you believe that vaccines, whether individually or collectively, contribute to autism?

[Dr. Casey Means]

The reality is that we have an autism crisis that's increasing and this is devastating to many families. And we do not know as a medical community what causes autism. The administration has just committed a huge amount of funding to look at the exposome of all environmental factors that could be contributing to autism. And until we have a clear understanding of why kids are developing this at higher rates, I think we should not leave any stones unturned.

[Senator Bill Cassidy]

There's been a lot of evidence showing that they're not implicated. Do you not accept that evidence?

[Dr. Casey Means]

I do accept that evidence. I also think that science is never settled.

[Megyn Kelly]

President Trump posting to Truth Social quote, For months, Senator Bill Cassidy of the great state of Louisiana has stood in the way of RFKJ's nominee, Casey Means, for the important position of US Surgeon General. In a subsequent post, President Trump adding, quote, hopefully all of the great Republican people of Louisiana, which I won big three times, will be voting Bill Cassidy out of office in the upcoming Republican primary. Senator Cassidy is speaking yesterday to reporters about the President's comments.

[Reporter/Interviewer]

What do you say to the President? Are you disloyal to the President of the United States?

[Senator Bill Cassidy]

To the United States of America. And I'm going to do my darndest and work with the President when we have a working for the best of the United States of America.

[Reporter/Interviewer]

Is he going to knock you out of your Senate seat?

[Senator Bill Cassidy]

President I don't think so.

[Reporter/Interviewer]

I mean, you're not concerned, you're not concerned about the President's opposition to you?

[Senator Bill Cassidy]

The people in Louisiana are going to vote for someone who's delivered for Louisiana. And I can look at the things that I have delivered for the state of Louisiana and it is far more than any of my opponents.

[Megyn Kelly]

In addition to Senator Cassidy withholding support means his nomination reportedly remaining stalled in committee after Republican Senators Susan Collins of Maine and Lisa Murkowski of Alaska declined to back her, according to the New York Times. In an interview with the Times, Means saying she will continue to advocate for the Maha movement, adding, quote, I genuinely believe in my heart that the Trump administration is trying to figure out how to move the balls forward. Yes, there are some setbacks, but there are some huge wins. And the way that culture has moved forward in the past year is monumental. Callie Means, brother to Casey, is a top advisor to Secretary Kennedy. Posting to X today, quote, Senator Cassidy worked to smear Casey as anti vaccine for not saying every American should submit their children to mandatory injections without parental or medical input, which is his view. Secretary Kennedy writing, quote, President Trump's Surgeon General nominee Casey Means stands as one of the Maha movement's most powerful evangelists. By sabotaging this appointment, Bill Cassidy once again did the dirty work for entrenched interests seeking to stall the Maha movement and protect the very status quo that has made America the sickest nation on earth. Yesterday afternoon, President Trump announcing the nomination of Dr. Nicole Safire for the Surgeon General position. She's a current Fox News contributor. Mr. Trump writing, quote, nicole is a star physician who has spent her year guiding women facing breast cancer through their diagnosis and treatment while tirelessly advocating to increase early cancer detection and prevention. She is also an incredible communicator who makes complicated health issues more easily understood by all Americans. Dr. Safire in the past making similar statements to those made by Casey Means, advocating for parental discretion regarding certain vaccines. A date for her confirmation hearing is not yet set. Maine Governor Janet Mills dropping out of the Democrat US Senate primary yesterday, clearing the way for controversial progressive left candidate Graham Platner to take on Republican Senator Susan Collins in the November general election. Governor Mills assumed to be the shoo in pick to challenge Senator Collins, who has held the seat since 1997 as Maine shapes up to be a crucial election for Democrats hoping to take back the Senate despite her establishment endorsements including Senate Minority Leader Chuck Schumer, Michigan Governor Gretchen Whitmer and Kentucky Governor Andy Beshear. Mills consistently trailing Platner in the polls, often by double digits. Democrat primary voters increasingly rallying behind Platner's message, centering on economic populism, anti establishment reform and pushing back against corporate influence in politics. Governor Mills releasing a statement, quote, while I have the drive and passion, commitment and experience and above all else, the fight to continue on, I very simply do not have the one thing that political campaigns unfortunately require today, the financial resources. The governor opting not to endorse Platner now running in the primary against two other candidates, each averaging a meager 2 points according to the RealClear polling average. Platner receiving endorsements from several high profile progressives, including Senator Bernie Sanders of Vermont and Senator Elizabeth Warren of Massachusetts. Platner's campaign raking in the dough reporting 4.1 million raised in the first quarter of 2026, in addition to 4.6 million raised in the previous quarter. Governor Mills campaign reporting about half that 2.6 million raised in the first quarter and 2.7 in the last one, according to Politico. Senator Collins on the Republican side raising about 3 million in the first quarter with 10 million already in the bank. Platner posting a video to social media yesterday following the governor's announcement.

[Graham Platner]

The win we get today, it comes because of you. It comes because of the work that you've done, that you've put into this. It comes from the fact that you guys believe in this kind of politics and that we're going to pull this thing off and we're going to make this happen and we're going to show the rest of the country that this is the politics of the future and that working people can organize and they can win.

[Megyn Kelly]

Platner maintaining strong support in the polls despite several early controversies. Heading his campaign in October, Platner turning to the Pod Save America podcast to publicly admit to having a Nazi linked tattoo on his chest. The ink a version of a skull and bones resembling a Totenkopf or death head associated with a Nazi paramilitary organization. Platner saying he was not aware of the connection when he and some fellow Marines got the tattoos while on military leave in Croatia. A former campaign manager disputing that account, calling Platner a history buff and saying he was well aware of the Nazi links. Platner also coming under fire for his prolific Reddit comments in which he posted a number of controversial statements. The Senate Republican's X account posting a video featuring an AI version of Platner reading some of the comments in question.

[Graham Platner]

Why don't black people tip? I work as a bartender and it always amazes me how solid the stereotype is. I got older and became a communist. Still got the guns though. I don't trust the fascists to act politely. I did used to love America, or at least the idea of it. These days I'm pretty disgusted by it all.

[Megyn Kelly]

Platner telling Politico he was, quote, effing around on the Internet at a time when I felt lost and very disillusioned with our government who sent me overseas to watch my friends die. I made dumb jokes and picked fights, but of course I'm not a socialist. I'm a small business owner, a Marine Corps veteran and and a retired shitposter. Platner has promised, if elected, to, quote, drag every single person in the White House by subpoena in front of Senate committees. Over and over again he has said he's open to adding seats to the US Supreme Court and wants to impeach President Donald Trump, Justice Thomas and Justice Alito. Great. Senator Collins speaking yesterday about the shakeup to cnn.

[Senator Susan Collins]

I'm sure this was a very difficult decision for Governor Mills and I wish her well. She has devoted her life to public service in the state of Maine.

[Reporter/Interviewer]

Will Platner be easier to beat in your view?

[Senator Susan Collins]

I'm not going to get into the November election at the this point, Senator

[Megyn Kelly]

Collins trailing behind Platner by 7.6 points according to the RCP average. The general election set for November 3rd. Coming up, a turning point. USA reporter attacked at an anti ICE protest. Now three members of the same family are facing federal charges and a new study linking greater meat consumption to lower dementia risk, but only for those with a genetic predisposition.

[PureTalk Advertiser]

Our sponsor, the Electronic Payments Coalition, says Washington politicians are always getting in your wallet and now they're messing with your credit card.

[Megyn Kelly]

They say your credit card and the

[PureTalk Advertiser]

security it offers are under attack.

[Megyn Kelly]

And that Senators Dick Durbin and Roger

[PureTalk Advertiser]

Marshall want to change the nation's payment system to benefit corporate megastores like Walmart and Target at the expense of you, the everyday American consumer. Credit cards can keep your payments secure. They can provide rewards that families help use to make everyday purchases much more affordable. And the Electronic Payments Coalition says that this Durbin Marshall thing, that it mandates

[Megyn Kelly]

letting corporate megastores cut corners on credit card processing and routing transactions over cheaper,

[PureTalk Advertiser]

untested networks with weaker security and fewer protections for you. Find out more about [e-mail] and consider telling Congress to guard your card.

[Megyn Kelly]

A federal grand jury indicting three individuals in connection with an alleged assault on Turning Point. USA Reporter Savannah Hernandez, 51 year old Christopher Ostrushko, 46 year old Dayana Marie Ostrushko, a married couple and their daughter, 20 year old Paige charged in the indictment. Christopher and Paige charged with interference with a federally protected activity and assault. Diana charged only with assault. The incident occurring April 11 at an anti ice protest held on federal property outside of the Whipple Federal Building in Minneapolis, the facility serving as an ICE field office and detention center. Hernandez telling Fox News tensions rose with the protesters when they discovered her association with TP usa. Videos filmed from multiple angles showing a group of people surrounding Hernandez shouting and blowing whistles and horns directly in her face as Hernandez attempts to walk away from the crowd. This moment recorded by Hernandez, who you hear asking to be left alone in this clip.

[Savannah Hernandez]

Get away from me.

Stop. Touching me,

You fucking talking.

[Megyn Kelly]

Another video showing Paige, the daughter appearing to throw several punches, then shoving Hernandez into a chain link fence. Mother Diana, seen on the video. Shortly after, Hernandez stands back up, appearing to lay a hand on the reporter. Then as Hernandez shouts, quote, stop touching me, Christopher steps in from behind, shoving Hernandez to the ground with two hands into her back. Savannah reporting she sustained a concussion Two sprains and bruises from the confrontation. Days after Christopher and Diana speaking out on the Pushing the Limits podcast, claiming they are not violent people.

[Podcast Host]

You are guys are making the claim that Savannah made physical contact first with your daughter. That's when your wife got involved. And then there was a little bit of a, for lack of a better term, mini scuffle.

[Christopher Ostrushko]

There was.

[Podcast Host]

And then at that moment when you pushed her in the back, you did that out of fear because you were protecting your family. And you are saying that your daughter and your wife were assaulted. Is that a fair characterization of your story of what took place?

[Christopher Ostrushko]

I believe that's a fair characterization. I mean, you, you said it and I, I, that's what I believe. And I just wanted her to leave. That's all I wanted. I just wanted her to leave so that this whole thing would stop.

[Megyn Kelly]

Acting Attorney General Todd Blanche posting to X. Hernandez was allegedly surrounded, physically assaulted and shoved to the ground simply because she was identified by the defendants as a conservative journalist. That is not peaceful protest. These deplorable actions, as charged in the indictment, will not be tolerated in America. And this Department of Justice will always punish unhinged acts of political violence. Hernandez, reacting to the charges Wednesday on Fox News.

[Savannah Hernandez]

I am incredibly grateful that both the FBI and DOJ have prioritized this and have brought these charges swiftly. So, I mean, I'm grateful for that and I really do hope that we see justice served and we see this case through because left wing violence has been a huge issue in this country for a long time. I'm not the first journalist this has happened to. I'm not, I'm hopefully going to be the last. But, you know, this sets a very strong precedent and sends a very strong message to the left wing that under this FBI, they're not going to be able to attack people anymore. And that in itself, to me, me means a lot.

[Megyn Kelly]

New research out of Sweden zeroing in on the link between diet and genetic risk for Alzheimer's. The findings, published last month in the Journal of the American Medical association, finding people with a certain genetic risk factor for Alzheimer's disease who consume more meat, particularly unprocessed meat like steak or ground beef, as opposed to bacon or deli meat, have lower risk of developing dementia. We spoke to the scientists behind the work, Dr. Sarah Garcia Tachik and Dr. Jacob Norgrian of the Karolinska Institute. At the center of it all, a gene everyone carries, the APOE gene, which comes in different variants. Some significantly increase a person's likelihood for developing Alzheimer's, Dr. Norgrian explains, we can

[Dr. Jacob Norgrian]

say that everybody has the APOE gene, and it comes in three different variants, the Apoe 2, Apoe 3 and Apoe 4. And you get one from each of your parents, meaning that there are six possible combinations, which we call genotypes. If you have the APOE4 gene, your Alzheimer's risk is higher compared to the APOE3.3, particularly if you have a double 4. So in this study, we studied the APOE3.4 and the APOE4.4 compared to the other genotypes. And these risk genotypes make up approximately a quarter of the population, but they account for the majority of Alzheimer's cases.

[Megyn Kelly]

Actress Gwyneth Paltrow says she's got the APOE4 gene. Actor Chris Hemsworth has two copies of it, dramatically raising his risk of Alzheimer's. The science is not settled on why APOE4 carriers face a higher risk of Alzheimer's, but research has linked the variant to higher cholesterol levels, with evidence suggesting buildup in the brain may interfere with neuron function and contribute to the plaque formation seen in Alzheimer's disease. According to the Wall Street Journal, APOE 4 carriers who consumed more unprocessed meat saw lower mortality and lower cholesterol than APO E4 carriers who ate less meat. The study showing that eating meat every day can lower the risk APOE4 carriers have to that of non carriers. Dr. Norgrian says there may be an evolutionary explanation for this.

[Dr. Jacob Norgrian]

What we know is that ApoE4 is the oldest genotype. ApoE3 is contemporary with modern humans. It's about 2,300,000 years old, and ApoE2 is even more recent. But the ApoE4 gene occurred for probably a few million years ago, and it might have been that our ancestors at that time consumed a more animal based diet and could possibly be adapted to a different diet than modern humans.

[Megyn Kelly]

The researchers suggest APOE 4 carriers may absorb more key nutrients from meat than they do from plant based foods, including nutrients like vitamin B12, iron and zinc that are linked to brain health. These findings also raise bigger questions about how we think about diet more broadly. Many public health guidelines take a one size fits all approach, but Dr. Garcia Tacek says this research underscores the role genetics play in determining the proper diet.

[Dr. Sarah Garcia Tachik]

I think one of the things our study shows is that brain health needs to be considered when we're writing dietary guidelines. We need to do more research on the cognitive effects of diet and in particularly, look at this effect of APOE and see if we can replicate it in other cohorts. We have to remind everyone that this is a relatively small cohort in Sweden and we need to make sure that this transfers to other populations in future. If we can replicate this across cohorts or even do a clinical trial and understand the mechanisms behind this, this would open the door for more of a precision nutrition or precision recommendations that are tailored to people's genotype.

[Megyn Kelly]

So how does one determine if they are an APOE4 gene carrier?

[Dr. Sarah Garcia Tachik]

There's a number of ways to get genotyped. It can be a blood test or other kinds of genetic tests. Some companies offer cheek swabs. It's not particularly complicated, but it's not usually done in routine clinical practice, at least not in Sweden. We do do it for individuals who are getting a workup for a suspicion of dementia.

[Megyn Kelly]

To those who say they'd rather not know, this is real, actionable data that may help prevent the onset of Alzheimer's. So maybe consider it. That'll do it for your AM Update, I'm Megyn Kelly. Join me back here for the MK show live on SiriusXM's the Megyn Kelly Channel 111 at New east, on YouTube.com Megan Kelly and on all podcast platforms.

[VRBO Premier Host Advertiser]

Premier hosts on VRBO deliver quality vacation rental stays with fast responses and clear instructions so you don't have to worry about surprises.

[VRBO Customer]

I asked our host a question about the house last night and he got back to me super quick.

[VRBO Premier Host Advertiser]

See, that's a premier host move right there.

[VRBO Customer]

I'll wish I had a premier group chat. I asked them where we should have dinner last night and they left me on red. I know you saw it. It says it.

[VRBO Premier Host Advertiser]

Classic group chat move. Don't walk into a surprise book a top rated verbo stay with a premier host. If you know you verbo.