What if the next life-saving medical breakthrough isn’t a brand-new drug, but an old generic hiding in plain sight, waiting to be matched to the right disease?

In this episode of The People’s AI, presented by the Vana Foundation, we explore the upside of AI and data when used to solve consequential problems, from AI drug discovery and drug repurposing to ambient AI in clinical workflows -- to climate change science and preventing wild fires -- and to the often-overlooked importance of data portability and health data interoperability.

Key moments

[00:00:00] A rare-disease crisis becomes a roadmap for a new model of discovery with Dr. David Fajgenbaum
[00:02:00] Why this episode focuses on the promise of AI and richer, more granular data
[00:06:00] The incentives problem: why there’s little profit in finding new uses for generic drugs
[00:10:00] Every Cure’s approach: scanning the world’s knowledge to score drug–disease matches at scale
[00:11:00] Dr. İlkay Altıntaş on turning data at scale into scientific insights, faster
[00:13:00] Wearables and digital biomarkers: what Oura-style data revealed during COVID-era research
[00:17:00] Personalized medicine, dosage, and the return of tailored treatment through AI assistance
[00:18:00] Wildfire AI and disaster resilience: integrating fragmented data to predict risk and act earlier
[00:26:00] Dr. Marschall Runge on the healthcare talent crunch and what AI changes in practice
[00:27:00] Ambient AI / AI medical scribe: why clinicians embrace it and what it frees up
[00:30:00] Interoperability: why health records still don’t talk, and what AI can and can’t fix
[00:33:00] Data portability, explained with Art Abal: why “your data should follow you” is still rare
[00:35:00] The most “locked” data today: health trackers and social platforms, and why it matters
[00:38:00] Competition, innovation, and antitrust: how data silos shape who gets to build
[00:42:00] Surprising matches: examples like Botox for depression and lidocaine around tumors
[00:45:00] A provocative future: early diagnosis at home, continuous signals, and faster intervention

Guests

Dr. David Fajgenbaum — Co-founder and President, Every Cure
Dr. İlkay Altıntaş — Chief Data Science Officer, San Diego Supercomputer Center (SDSC)
Dr. Marschall Runge — Author, The Great Healthcare Disruption
Art Abal — Co-founder, Vana

The People’s AI is presented by the Vana Foundation, supporting a new internet rooted in data sovereignty and user ownership, where individuals, not corporations, govern their own data and share the value it creates. Learn more at Vana.org.