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Dr. Ali Crum
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Dr. Ali Crum
I turned off news altogether.
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I hate to say it, but I.
Dr. Ali Crum
Don'T trust much of anything.
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It's the rage bait.
Dr. Ali Crum
It feels like it's trying to divide people.
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We got clear facts. Maybe we can calm down a little. NBC News brings you clear reporting.
Dr. Scott Barry Kaufman
Let's meet at the facts. Let's move forward from there.
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Dr. Ali Crum
I think that what meditation does, what mindfulness does, is it helps you realize that you have mindsets, that the world, your beliefs aren't just sort of a reflection of reality as it is that like, could be this way or could be that way. And you kind of like sit back and you sort of see the kind of absurdity of it all. So that's part of it. But then what, right? Then you need to go live your life. Like, then you need to get back in the game. And so it's, you know, it's stepping back in and saying, now I'm going to live my life and I'm going to choose to view stress as enhancing.
Dr. Scott Barry Kaufman
Hello and welcome to the Psychology podcast where we explore the depths of human potential. I'm your host, Dr. Scott Barry Kaufman, a cognitive scientist and Columbia professor. On this episode we have my dear friend Dr. Ali Crum, whose research focuses on how changes in subjective mindsets, the lenses through which information is perceived, organized and interpreted, can alter objective reality through behavioral, psychological and physiological mechanisms. Her work is in part inspired by research on the placebo effect, a remarkable and consistent demonstration of the ability of the mindset to elicit healing properties in the body. She is interested in understanding how mindsets affect important outcomes outside the realm of medicine in the domains of behavioral health and organizational behavior. More specifically, she aims to understand how mindsets can be consciously and deliberately changed through intervention to affect organizational and individual performance, physiological and psychological well being and interpersonal effectiveness. This chat was very sentimental to me personally. I met Dr. Crum in graduate school at Yale and we connected immediately. I remember fondly our deep chats and I'm so proud to see her become such a superstar in the field. I hope you find this chat just as informative as I did. So, without further ado, I bring you Dr. Ali Crum. Oh my God, Ali. How do you look exactly the same?
Dr. Ali Crum
I mean, you look exactly the same. It's so good to see you.
Dr. Scott Barry Kaufman
So good to see you too. I mean, like, you're exactly like, you know, Yale dance. What was that? I don't know, some party gypsy bond. I think it must be something. Yeah, the memory I have of you in my mind is like exactly the same. Anyway, congratulations on keeping your health and vitality in youth and for your amazing, amazing ascendancy in the field. Of psychology successes and research and everything. It's been such a delight and honor to watch you soar.
Dr. Ali Crum
Oh, my gosh. Well, I feel the same about you, Scott. I like I seeing you brings me right back to New Haven. You know, I remember going to your dissertation, remember meeting your mom right outside of the hall of Graduate Studies. And, you know, just we were just, you know, we were so such kids then. But at the same time, you know, I think both of us, I was drawn to you because I got a sense that this was your passion, right? This was your calling. And you weren't doing it to get some credentials. You were doing it because you knew it mattered. So it's been fun to watch from afar and listen to all your work and.
Dr. Scott Barry Kaufman
Likewise. Thanks. Thanks. Well, let's back up before we even met. Let's back up to your undergraduate at Harvard. Hova. You were a TA for a very special and popular course on happiness by Tully, is that correct?
Dr. Ali Crum
Yes. Tal Ben Shahar changed my life.
Dr. Scott Barry Kaufman
Can you tell me a little bit about that experience and how it influenced you for the research you've continued to do?
Dr. Ali Crum
For sure. I mean, I think in order to understand the effect that that class had on me, it's important to share a little bit about my childhood. So I grew up in a household. My father was a teacher of Transcendental Meditation. He was a master of the art of aikido. He started a foundation called Windstar foundation with John Denver, the singer songwriter, where they would host speakers retreats, where people would come basically to study in the mind body arts. And so I grew up going to all these retreats. You know, my summers were filled going to meditation and aikido seminars and retreats. And so when I got to Harvard, I realized, you know, fairly quickly that that was not a normal upbringing, that that wasn't the status quo for the other students there. And, you know, for a while, I was a little bit lost. I was feeling, you know, a sense of imposter syndrome, a sense of, like, you know, I, I, I've learned a lot, but I haven't learned all they know in terms of, you know, the academics. But it wasn't until I met Talb and Shahar, Ellen Langer, Anne Harrington, that I realized that, you know, even though my childhood was unique, it was, it was actually being researched at the time from a neuroscientific standpoint. You know, the rise of positive psychology was happening. The nerve, excuse me. The neuroscience of meditation was just beginning, and people were starting to take this work really seriously from A scientific standpoint. So that class, you know, it didn't necessarily, like, open my mind to things that I hadn't learned or heard of before, but it made me feel at home. It made me feel like I belonged.
Dr. Scott Barry Kaufman
So you did some. You contributed to some seminal research, even as an undergrad in Harvard, which I think paved the way for a career on mindsets and stress. So can you talk about some of that seminal research?
Dr. Ali Crum
Yeah. So the original research that I did, you know, I mentioned I had sort of been. I had experienced the power of the mind to affect the body, both through watching my dad teach meditation, teach aikido and the martial arts, also as an athlete. I was a elite gymnast for a number of years, and then I was a Division 1 athlete at Harvard. I was an ice hockey player. And I was taking a class actually with Ellen Langer at the time. And she said, you know, you know, I think I came back all sweaty from a practice to lab or class or something. And she was like, ah, you know, exercise, that's just a placebo. And I was sort of like, wait, what?
Dr. Scott Barry Kaufman
Really?
Dr. Ali Crum
What are you talking about? And, you know, but it caught my attention. And, you know, I think at the time, I was really struggling with this sense, this question of, like, what is enough exercise? Like, I was training two to three hours a day, and then I would, like, go work out after practice even further. And it kind of got my attention. I was like, what if it's all in my head, the benefits of what I'm doing? So I started researching placebo effects, actually sequentially. Ann Harrington was teaching a class on the history of medicine, and she made a comment one day in class that some. She said something like, in many ways, studying the history of medicine is like studying the history of the placebo effect. And so these two things kind of got in my head. Wow, what is the placebo effect? How strong is it? And I did a lot of research looking into that. And then the study that Ellen and I did was looking at hotel housekeepers. We found that they were getting a lot of exercise but weren't aware of it. And what we found was if we could make them aware of that, help them to see not only are they getting above and beyond the Surgeon General's requirements, they are. You know, they're probably getting more exercise than most people in the United States. That that shift in mindset didn't just change how they felt, but also had measurable changes on their blood pressure, their body fat, their weight, and so forth. So that really kicked it off.
Dr. Scott Barry Kaufman
For me, yeah, that's pretty revolutionary research. Pretty revolutionary foundation.
Dr. Ali Crum
Thank you. Yeah. I think what it did was brought two fields together that hadn't been integrated before. There was all this work on behavioral health being, you know, the modern medicine. Right. We need to eat well, we need to exercise, we need to stop stressing, we need to stop smoking. And it's brought the research on placebo response into that and said, well, yeah, we do need to do all those things, but also, we need to pay attention to our beliefs, to our mindsets, to how we're thinking about these things.
Dr. Scott Barry Kaufman
Yeah, for sure. And then when you got to Yale, you worked on. You continued this research, you published this paper in 2011 called Mind over Milkshakes. A classic, classic in the field. Mind over milkshakes, not just nutrients, determine ghrelin. Is that how you say it? Response. So can you just tell what is ghrelin? You know, and I know it's related to hunger, but give me a little more technical description and, you know, how does our mindset affect that?
Dr. Ali Crum
Yeah. Well, first of all, do you remember, I think I asked you to read a draft of this paper back in New Haven? Maybe it hadn't made such an impact yet, But I remember 2009, something like that. We were sitting at a restaurant somewhere in New Haven, and I had given it to you to read because I was struggling with how to frame it, but you were really helpful.
Dr. Scott Barry Kaufman
Oh, yeah. Isn't that funny?
Dr. Ali Crum
It is funny. It's all full circle. But, yeah. So this study, quite frankly, this is my favorite study I've ever done it mostly because of how profoundly it changed my life as a result. So ghrelin is a hunger. Hunger hormone. Medical experts call it the hunger hormone. It helps regulate hunger and metabolism. So, you know, I don't know what time it is. I think you're in New York, so maybe you've already eaten lunch, but I haven't yet. So my ghrelin levels are slowly rising, and the purpose of that is to send signals to my brain and body that I need to seek out food. So rising levels of ghrelin signal hunger. And also rising ghrelin slows metabolism just in case we don't get the food that we need. And then theoretically, or at least prior to the study, it had been assumed that in proportion to the amount of calories you consume, ghrelin levels will drop. So say I go out after we chat, and I have a giant hamburger and a milkshake. Then my ghrelin levels will plummet, telling my brain okay, you can stop feeling hungry, stop searching out food, and I'm going to rev up the metabolism to consume the food that you just ingested. So, you know, actually these, these gut peptides, these hunger hormones, hadn't really been fully discovered until the late 1990s. And we're still just now figuring out what they do and how they work in concert. But what we were interested in in this study was does our body's physiological response and in particular our body's ghrelin response, does that differ, might that differ if we have different beliefs about the food that we're eating? In that study, we worked with the Yale New Haven Hospital and we gave people the exact same milkshake. So it was about a 350 calorie milkshake. And we either told them that it was 620 calories, high fat, high sugar, or 120 calories, 140 calories low fat, sort of sensible diet shake. And we had them hooked up to an iv. We were measuring ghrelin levels through their bloodstream. And what we found was that even though the shakes were exactly the same, when people thought they were consuming an indulgent shake, their body responded as if they had had more food. So the drop in ghrelin was about three times as great compared to when they thought they were consuming a sensible kind of low fat diet shake.
Dr. Scott Barry Kaufman
That sounds like a big effect statistically. Can you like, subjectively describe what that difference is? Does that make sense?
Dr. Ali Crum
Totally. So. Well, first of all, the findings were significant, important in the sense that no one had ever documented just any physiological change based on the belief. So that was one thing that was important. But the second reason why this study was important was realizing actually the direction in which the belief had an effect. So I went into this, remember, like, thinking, okay, placebo effects are basically, if you think you're going to be healthy, you'll have a healthy response. So I assumed that the sensible shake, if, you know, if it made any difference at all, that would be the better mindset to be in. And what we found was exactly the exact opposite. Right. Assuming you want to maintain or lose weight, when, if you're consuming something in the mindset that you're eating sensibly healthy, it conveys to the brain a sense of, of scarcity or restraint. This sense of, like, I didn't eat enough. And what that does is it perpetuates ghrelin, perpetuates the hunger signals, slows metabolism, and so forth. So the mindset of sensibility or restraint or Scarcity actually counteracts the hard work that you might be doing actually reducing your caloric intake. Does that make sense?
Dr. Scott Barry Kaufman
It does. But the effect you found of three times less is that the equivalent of literally going from signaling that it's time to eat versus like I don't feel any hunger at all or is it like just not as strong or. I guess I'm trying to qualify. Qualify it, not quantify it.
Dr. Ali Crum
Yeah, I, I don't know. It was three fold greater compared to the sense.
Dr. Scott Barry Kaufman
Definitely an important effect. It's definitely important.
Dr. Ali Crum
But how much did that affect their subjective sense? And honestly I. The subjective sense is less important than the physiological sense.
Dr. Scott Barry Kaufman
That's a good point. Yeah.
Dr. Ali Crum
In that, in this case, and I think everybody's different and I think, you know, I've since that time wanted to do my sort of dream study is, you know, because I was just. They were sitting in there for two hours, right? We're measuring their response to the shake. So it's like, okay, how much does this really matter? But you know, what if we could take somebody over the course of a month, right. And not only change their diet but change their beliefs about what they're eating. So maybe they're starting a low carb diet diet or low fat diet or whatever it is. But if they believe that it's enough, will that actually change weight, change their body composition and so forth. But we haven't been able to do that because as you can imagine, it's hard to deceive people for a long period of time. And we wouldn't want to deceive them for a long period of time.
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Hey everyone, Ed Helms here. And hi, I'm Kal Penn and we're the host of Irsay, The Audible and iHeart Audiobook Club. This week on the podcast, I am sitting down with Jenny Garth, host of the iHeart podcast. I choose me to discuss the new Audible adaptation of the timeless Jane Austen classic Pride and Prejudice. This is not a trick question. There's no wrong answer. What role would I play?
Dr. Ali Crum
You know what? I can see you as Mr. Darcy. You got a little call in Firth.
Kal Penn / Ed Helms (Podcast Hosts)
Okay, that's really sweet. I appreciate that. But are you sure I'm not the dad? I'm not Mr. Bennett here. Listen to Earsay the Audible and iHeart Audiobook Club on the iHeartradio app or wherever you get your podcast.
Dr. Scott Barry Kaufman
Hi all. I want to take a moment to make a few important announcements that I'm really excited about. As you all know, I'm committed to helping people self actualize. In the service of that, I just had a new book come out called Rise Overcome a Victim Mindset. Empower yourself and realize your full potential. In this book I offer a science backed toolkit to help you overcome your limiting beliefs and take control of your life. Are you tired of feeling helpless? This book will offer you hope. Not by identifying with the worst things that have happened to you, but by empowering you to tap into the best that is within you. Rise above is available wherever you get your books. Are you a personal coach looking to take your coaching to the next level? I'm also excited to tell you that our Foundations of Self Actualization Coaching three day immersive experience for coaches is backed by popular demand. Foundations of Self Actualization Coaching is a course offered to enhance your coaching practice by offering you evidence based tools and insights to equip you to more effectively help your clients unlock their unique creative potential. You can learn more about the course and register by going to centerforhumanpotential.com sac that's centerforhumanpotential.com Sac okay, now back to the show. No, that's cool. That's really cool. Well, you've done some really great extensions of this work. In 2013 you teamed up with Peter Salovey, who was he head of the Yale Graduate School at that time? I think.
Dr. Ali Crum
Yeah, he was, I think Dean when we started to work working together and then Provost when I left.
Dr. Scott Barry Kaufman
Yeah. Great. And. And this guy called Sean Acre was a co author in this paper as well. But you are the lead author. I want to state for the record, you're amazing. Ali Crumb. And this, this paper is rethinking stress. The role of mindsets in deterring the stress response. And so what I want to talk about in this paper is you developed a measure called the stress mindset measure. Can you give me. I hate to put you on the spot, but can you give me one or two items like how do I know if I score high on this measure?
Dr. Ali Crum
Yeah, of course. You love self report psychometrics, you ask.
Dr. Scott Barry Kaufman
I love psychometrics.
Dr. Ali Crum
I do too. So we have that in common. So this is the stress mindset measure. The SMM asks questions like experiencing stress enhances my performance and productivity. So do you. Strong. You know, do you disagree with that? Agree with that? Strongly agree with that, experiencing stress depletes my health and vitality. That one is reverse scored. Experiencing stress. I think we had a health and performance vitality. Oh, it enhances my learning and growth. So we wanted to cover these sort of three dimensions. Health and vitality, learning and growth, performance and productivity.
Dr. Scott Barry Kaufman
And for the record, these items, if you score high in this, it's not the majority of participants who tend to think this way. Way. Correct. I mean, most of us don't think, when I say stress to every person on the street, they don't think, oh, that's going to improve my performance. So what were percentages and things?
Dr. Ali Crum
Yeah, I think our, you know, we've studied this now in many different populations. It's been translated in many different languages. And the average score is always, almost always below the midpoint. So categorically you would put that into the belief that stress is debilitating. The only group, at least that I've sampled in my life so far that is on average in the enhancing side of the scale over the Midpoint are Navy SEALs. And it makes sense, right? These are people who are literally choosing to go into some of the most stressful experiences you could dream up, in part because they know they can handle it and they know they'll, they'll thrive under. That makes sense.
Dr. Scott Barry Kaufman
I mean, I'm sure that like the whole West Point cadet, you know, vibe is, is that, you know, when they come in. And so you found. This is so cool. You found that those who score higher on the scale showed moderate cortisol reactivity and high desire for feedback under stress. Now, this is not the norm. This is not the norm. So explain the really important implications of this kind of these changes to cortisol and your desire for feedback under stress.
Dr. Ali Crum
Yeah, well, first of all, it's important to kind of take a step back and understand what this measure is. Right. So, you know, the truth about stress is that it is a paradox, right? There's lots of research showing that stress can have damaging effects on our health, on our learning, on our growth, on our well being and so forth. But if you actually dive deeper into the literature, you realize that, you know, it's not all bad. And in fact, the body stress response was not designed to kill us. Like, it was not designed to hold us back. It was designed to help us rise to the occasion, to meet the demands we're faced with. In fact, Hans Selye, who sort of, you know, humorously called the father of stress when he first wrote about stress, he wrote about the stress responses non Specific, Right. It's just the body's reaction to the challenges that it faces. And he also talked about, you know, not just stress as only bad, but stress as being both distress when it causes negative effects and eustress when it actually helps the brain, body system grow, learn, perform. So we want to distinguish between kind of what is the true nature of stress, which is like most things in life, a paradox, many types of outcomes are possible and what we're interested in, which is our belief or mindset, the core assumption that we have about the nature of stress. Now if you probe somebody further, they might say, well I get that it could be good here and da da, da, they can get all nuanced in their thinking. But you know, when we operate, when we act in the world, we are acting based on these default assumptions, right? Our first inclination is going to be based on where on that scale did we stake our claim on average. And so there's variability in that. Even though on average most people are on the stress of debilitating side, there's variability in people's beliefs. And what we find is that that variability matters. So people who believe hold the mindset that stress can be enhancing, they show more adaptive cortisol response. And I'll talk about that in a second. And they also show more willingness for feedback. And it makes sense, right? If you think that stress is bad for you and then you're faced with something stressful in your life, how do you feel right now? Not only are you stressed because something just happened, but now you're stressed about the stress and you're upset that you're stressed and you're a little depressed that you have to deal with the stress and you're worried about the cardiovascular ramifications of the stress. So the mindset itself just made the stress stress worse. So emotionally it changes motivationally. We also are influenced by our mindset. So if you believe that stress is debilitating, that it's bad for you, that it's going to kill you, what are you motivated to do? You're motivated to either, yeah, to like get the hell out of there. Like either pretend that this problem isn't there, you know, that you're, you're boyfriend or girlfriend didn't just give you negative feedback or to overcompensate, to overreact, to like make sure this problem goes away. So those two responses, either hyperactivity around the stress or you know, avoid and hypoactivity show up physiologically. So either people freak out or they check out. And what we found is people who believe that stress can be enhancing. They're somewhere in the middle. They're like, okay, I didn't want to be dealing with this stress, but it's here. And the stress response is designed to serve me. So what do I have to learn from this? How can I engage with this in an appropriate, thoughtful, useful way? What feedback do I actually need to hear? And that shows up physiologically in moderate levels of cortisol, which is important because most people get this wrong. They think cortisol is all bad. But actually, you know, cortisol is linked with attention, focus, engagement. Right. So you want to be somewhere in the middle with respect to cortisol.
Dr. Scott Barry Kaufman
You know, there's an old saying that goes, when you worry, you suffer twice. And you had me thinking that it's, you know, you have the stress, but the whole avoidance and we should use the word fear that enhances.
Dr. Ali Crum
Yes.
Dr. Scott Barry Kaufman
These reactions and these physiological responses that cause damage to your body, quite frankly, and your mind. So in some ways it's like a double whammy. You know, you have the stress itself and then you also have the avoidance response. So it just seems like the more you can have this stresses enhancing mindset, the more you're kind of like avoiding a double whammy. Does that make any sense?
Dr. Ali Crum
Totally. You know, in some of the work that I did with Peter Salovey, he coined the term emotional intelligence. Back before Dan Goldman rolled with. Yes, yes, yeah, David Caruso. But one of the things I remember Peter talking about, and later Mark Brackett and others, is this idea of dirty discomfort. So you have clean discomfort, which is like the stress or the fear or the sadness. And then you have dirty discomfort, which are your judgments and concerns about the discomfort. Like, I can't believe I'm feeling this way. I shouldn't be feeling this way. This is going to be harmful for me and so forth. And so, you know, it's. It's nuanced. Right. The goal is not to, you know, get rid of all negative feelings. Right. It's to feel them but not make them doubly damaging, as you say, not make them worse. Right. There's enough to learn from them. And that's important, I think to say with respect to this stress is enhancing mindset is sometimes people misunderstand that. They think, oh, that means that you should seek out more stress in your life. And it's like, well, no, like, if you care about anything in life, you're going to experience stress surrounding it. In fact, you know, the definition of stress at least that I use is stress is the experience or anticipation of encountering challenges in your goal related efforts. That's super jargony. But like, you know, for all intents and purposes what matters is that you only experience stress in domains that you care about. Right. If I told you that Johnny was failing school, you wouldn't really be stressed about that unless you were Johnny or your son was Johnny or you cared about the Johnny's of the world. So we're going to have stress in our life. You don't need to seek it out. A stress is enhancing mindset also doesn't mean that the stress stressor is a good thing. And I think you know, you know this with all your work on trauma and your great book that you just wrote recently. Like, you know, when you say you can rise above, right. Trauma, it doesn't mean that like the trauma was a good thing. Like stress, the stressor is not a good thing. But going through it can lead to enhancing outcomes and that mindset makes those outcomes more likely.
Dr. Scott Barry Kaufman
Yeah, it seems like a bedfellow of a Carol Dweck's growth mindset, but applied to a different domain.
Dr. Ali Crum
Exactly. Yeah. No, Carol's work has been very inspirational. I think her use of the term mindset to kind of define a core belief that we have about the nature of intelligence as fixed or malleable is just so profound and important. And what we're doing here is we're trying to, you know, expand that, but it's different right now the topic is stress and the modifiers are, you know, is stress enhancing or debilitating? Not necessarily growth or fixed. Right. So it's. We have mindsets about all sorts of things and they. Turns out they matter.
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Dr. Scott Barry Kaufman
They see us.
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Crypto trading involves risk of loss and is offered to US customers excluding New York and Maine through PayWord Interactive, Inc. View legal disclosures@kraken.com legal disclosures terms and conditions apply. Time for a Sofa Upgrade Introducing Annabe Sofas where designer style meets budget friendly prices. Every Ana Bay sofa is modular allowing you to rearrange your space effortlessly.
Dr. Ali Crum
Perfect.
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Perfect for both small and large spaces, Anabe is the only machine washable sofa inside and out. Say goodbye to stains and messes with liquid and stain resistant fabrics that make cleaning easy. Liquids simply slide right off. Designed for custom comfort, our high resilience foam lets you choose between a sink and feel or a supportive memory foam blend. Plus our pet friendly stain resistant fabrics ensure your sofa stays beautiful for years. Don't compromise quality. For price, visit washablesofas.com to upgrade your living space. Today sofas start at just $699 with no risk returns and a 30 day money back guarantee. Get early access to Black Friday now. The biggest sale of the year can save you up to 60% off plus free shipping and free returns. Shop now at washablesofas.com offers are subject to change and certain restrictions may apply.
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Kal Penn / Ed Helms (Podcast Hosts)
So let me get this straight. Your company has data here, there and everywhere, but your AI can't use the data because it's here, there and everywhere? Seems like something's missing.
Dr. Scott Barry Kaufman
Every business has unique data. IBM helps your AI access your data wherever it lives.
Kal Penn / Ed Helms (Podcast Hosts)
To change how you do business, let's create smarter business. IBM.
Dr. Scott Barry Kaufman
They do matter and we can get even nerdier. You proposed a metacognitive approach to mindset change. Just when you thought it didn't get nerdy enough. You create your stress mindset scale. What is the metacognitive approach that you published in 2023 where you evaluate your rethink stress mindset intervention from 2013? Yeah. Anyway. Yeah, let's go.
Dr. Ali Crum
I'm so glad we get to nerd out together, Scott.
Dr. Scott Barry Kaufman
Me too. It's been too long.
Dr. Ali Crum
We need a better term for this, but it's so crucial. The truth of stress is a paradox. Our mindsets matter if we know the goal is to get people to adopt more of a stresses enhancing mindset because we know that's useful for them. How do we do that? One approach could be to just try to convince them that that's the true mindset, that's the right way to think about stress. And in fact, we did that in that early study with Peter Salovey and Sean Acre. We worked with UBS bankers who were going through layoffs after the 2008 financial recession. And what we did, we gave them three minute video clips that shared the science, science of stress anecdotes, et cetera, but they were oriented towards one or the other of these truths. So, you know, one group in the study saw all the information that kind of reaffirmed how bad stress is for you, and the other group saw all the information that showed that stress actually wasn't designed to be that way. It was designed to support your immune system and narrow your, your attention in ways that can support you. And what we found is over the course of the week, just watching those videos did change their mindset, and it did have effects on their health and performance. But I left that study feeling like, you know, that wasn't really ideal because it's not fully true. Right. Like we're not lying to people. Everything that we put in those films were, you know, was based on evidence or it was a true anecdote, but it wasn't the full picture. Right. So then I was left with this question of how do we get people into the mindset that stress can be enhancing? Not by kind of, you know, you know, trying to teach them or getting them to see that that's the true nature of stress, but by getting them to see that that mindset is useful.
Dr. Scott Barry Kaufman
Yes.
Dr. Ali Crum
And so what we decided to do was to create an intervention where people learned the true nature of stress. They learned all the whole messy story of stress. It can be the worst thing for you. Right. And some people really thrive and grow from stress. All of these things are true. And your mindset about it matters. It can shape Your attention, it can shape your feelings, it can shape your motivation, it can even change your body. So you choose. Right. Like, how do you want to choose to view stress? Right. Do you want to view it as debilitating or do you want to view it as enhancing? So by meta mindset, what we mean by that is we inspire people to adopt the mindset. A particular mindset, such as the mindset that stress can be enhancing not because they're manipulated into it because. But because they choose consciously that that mindset is a more useful one to have.
Dr. Scott Barry Kaufman
Well, so it's just like a flexible stress mindset. Yeah, strategically flexible.
Dr. Ali Crum
Yeah. It's sort of like, you know, I think that what meditation does, what mindfulness does, is it helps you realize that you have mindsets, that the world, your beliefs aren't just sort of a reflection of reality as it is. That, like, it could be this way or it could be that way. And you kind of like sit back and you sort of see the kind of absurdity of it all. So that's part of it. But then what? Right? Then you need to go live your life. Like, then you need to get back in the game. And so it's, you know, it's stepping back in and saying, now I'm going to live my life and I'm going to change. Choose to view stress as enhancing.
Dr. Scott Barry Kaufman
It's my life. Okay, where's your piano? I don't know, but I can beatbox. No. So I mean, this is this. There's a whole. There's so many extensions, so many offshoots of this. I mean, where there's some fascinating stuff found that you can change cancer mindsets. You know, a brief mindset focused digital intervention was effective at improving physical, social, emotional and functional hr Q O L. Okay, what does that mean?
Dr. Ali Crum
You gotta love jargon. Yeah. So, you know, we did the stress mindset stuff. That stuff's still ongoing. So important as you know, sadly. Well, we can come back to this. But I thought, you know, we would do this research and then everybody would learn about it and then everybody would have a stresses enhancing mindset. I think, sadly, you need to write that book. I'm working on it.
Dr. Scott Barry Kaufman
Yeah. Yeah.
Dr. Ali Crum
But sadly, I feel like our culture has even taken a step back in having this belief that stress is bad, all stress should be avoided. We should protect everyone from stress and so forth. But we can talk about that. The cancer work is really near and dear to my heart. This is work that I've done with Shawn Zion, former grad student in the lab Lydia Shapira and others, Jonathan Barak. And we wanted to understand what are mindsets that people have about cancer. And, you know, what we learned is that, you know, like stress, there's, you know, cancer is complicated. It doesn't just have one effect on people's lives, but people have mindsets about it. Three of the mindsets that we know people hold are, you know, either you view it as kind of an unmitigated catastrophe. My life as I knew it was over. Nothing will ever be the same. Why me? Poor me. You know, yeah, the cancer is a catastrophe. But people can also view it more as something that's manageable. Right. They have a mindset that, yeah, I'm diagnosed with cancer, this is not what I would have hoped for. This is not what I wanted, but I can manage this. I can handle this. And there's a third mindset that we see actually quite frequently in people with cancer, and that is that cancer can be an opportunity. So again, that doesn't mean you wanted it doesn't mean it's a good thing in and of itself.
Dr. Scott Barry Kaufman
Post traumatic growth potential for post traumatic growth.
Dr. Ali Crum
Exactly. The experience of going through cancer can, yeah, help you reorganize your priorities, help you, you know, deepen your values, help you self actualize, help deepen your relationships. And you know, unlike stress, actually in the normal population, when you look at people with cancer, this is actually pretty strong. Right. And I think when you're really faced with tough things, you kind of are forced to see the light in it, to see the silver linings. But here again, there's lots of variability. And what we find is that interestingly, these mindsets aren't correlated with the severity of cancer. So you have people who have stage 4 metastasized cancer who believe it's an opportunity, feel like it's manageable, and you have people with stage one, no big deal kind of cancers that feel like their whole life's over. And here again, these mindsets matter in shaping how people feel, how they're motivated to engage with treatment, how their bodies are responding physiologically, and what they pay attention to in their treatment. And the intervention that we designed is also a metacognitive strategy to changing people's mindset. So you can imagine, you know, we didn't want to go in and say, hey, you who just was diagnosed with cancer, you should think this way or this is the right way. We don't do that. What we do is we showcase stories from former people who have been formally diagnosed. They're cancer survivors. Talk about the role of their mindsets in the cancer journey. And they're not just the people who had great mindsets for the start. They're people who initially felt like this was a catastrophe and then realized the impact of their mindsets, chose more useful mindsets and reaped the benefit of doing that. So the intervention is watching others talk about their mindset. And what we show in that study is that, you know, that intervention, which is a total of about an hour long of documentary style films, changes mindset and that confers the benefit on health related quality of life. So health related quality of life is, you know, basically how well are you functioning? Are you getting up and doing the things that you want to do? Are you, you know, you feel good about your relationships? Are you physiologically, in terms of symptom, sort of managing okay, that's cool.
Dr. Scott Barry Kaufman
There's another category of people that you might want to consider in your further studies on the topic. There was a woman who got a lot of press for the way she handled her cancer diagnosis. She was told that she had stage four cancer and maybe had two years left to live. And she decided she was going to completely surrender to it. Actually not. She said, I'm not going to fight. I'm not going to fight a battle with cancer. I'm going to enjoy my life for two years and accept it. Accept that I only have two years left. And I just don't feel like you don't hear that about that option often enough. You find like you're almost like feeling pressure to fight it to, you know, oh, yeah, what are you doing to fight it? What are you doing to fight the battle with cancer? Cancer. She's like, I don't want to fight the battle with cancer. I want to enjoy my life. And so that's just. It might be an interesting. If you get a large enough sample.
Dr. Ali Crum
Of people like that, 100%. I'm so glad you brought that up because I think Sally Crumb, another place where people misinterpret the work, you know, and, you know, having the mindset that cancer is an opportunity or cancer is manageable doesn't mean you're kind of happy about cancer. It also doesn't mean you're sort of denying. Also doesn't mean you're 100% going to beat it. Right. It's just to get there. The first step is really to acknowledge and accept the reality of your diagnosis.
Dr. Scott Barry Kaufman
Yes.
Dr. Ali Crum
And it's only when you do that that then you can choose how you're going to handle that. How you're going to approach it. And that might mean going all in and getting the treat, every single, you know, treatment that you can. Or it might mean, you know, I don't want to do that. I want to live out the rest of my days, you know, doing something else. But you can only get there through acknowledging it and through having a mindset that is useful.
Dr. Scott Barry Kaufman
Yeah, I want to shift a little bit to what happens when you get information about yourself and how that changes those actual things without you trying to change them. So that's a long winded way of talking about a study that you were a co author on with Chernwald and colleagues in 2019. Learning one's genetic risk changes physiologic physiological physiology independent of actual genetic risk. I mean, that's mind blowing. I mean, it's just so mind blowing to me. Okay. Because so many of us are able with 23andMe, right. We're able to find out all this information about our genetic risk estimates for this and that. Alzheimer's, cancer, obesity, all sorts of diseases. What did the study find about just merely learning about that?
Dr. Ali Crum
Yeah, this was such an interesting and fun study to run. We got people into the study under the study guise that we were looking at how personalized medicine, how we could create sort of personalized fitness plans. And this was very believable in the Stanford area. Lots of stuff on, on genome mapping and personalized medicine were happening at the time. And we in particular were interested in one gene called the CREB1 gene. And that gene had been linked with obesity and weight through exercise capacity pathways. So people with the risk allele of the CREB1 gene were essentially associated with less cardiovascular efficiency. When they exercise, you would run, you feel not very good at it. It's painful to run. And the theory was that was linked with part of the reason why these people had higher rates of obesity. What we were interested in in the study was what do your beliefs about your genetic risk influence the physiological effects of that gene? So not just. Well, first of all, 23andMe was big. Lots of this genetic genotyping was getting more and more common. And the theory was, I think that if you got information about your risk for certain things, that that would motivate you to compensate and engage in behaviors that would make you healthy. And a meta analysis had been done to show basically that that just wasn't true at all. Like, people would be told they were at risk for all these things and it just didn't motivate them to be any Healthier. So that was interesting. But what we were interested in in was even more kind of fundamental, which was if you believe that your genes make you bad at exercise, will that actually will that just the belief will change the genes.
Business Advertisement Narrator
Change.
Dr. Ali Crum
Yeah, change the genes express. Yeah. And so what we did was we. This was also a within subject study, like the milkshake study. So it was the same people did the same VO2 Max test. It was a cardiovascular efficiency test. This was done at the human Performance Lab run under Scott Delp. We hooked them up. We were literally measuring the amount of oxygen they were intaking and how efficiently they were able to convert it to carbon dioxide through their lungs. We did one exercise test, very stringent. It's sort of like a stress test if you know, if you've ever done one or a VO2 max test. And then we had them do the exact same test one week later. But before they did it, we gave them their genetic result.
Dr. Scott Barry Kaufman
Okay.
Dr. Ali Crum
So we gave that on this very official looking pamphlet and we said, you know, we just want to give you some important information that we got from your genotype. And they looked at it and half were told they had the risk allele, that they were the people who were likely to have lower exercise efficiency, or they were told they had the protective allele, that they had the good gene. Right, like this. They had the type of gene that made them good at exercise, basically. And then we had them run again the exact same test. Now what was interesting about this is we had their actual genotype too. And so we had their actual genotype and then we randomized them to getting the information. So the information they got was randomly determined. Therefore, we can separate the effect of the actual gene on the outcome and the perceived genetic risk on the outcome. And essentially what we found was the perceived genetic risk mattered. When people thought they had the risk allele, they converted oxygen into CO2 in a far less efficient rate. They also, you know, felt hotter, more pain, less motivation, you know, all a lot of other effects as well. But the physiological results were, were really interesting. And it was fully shaped by belief, not their genetics risk.
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Dr. Ali Crum
Chocolate ice cream. Sure thing.
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Dr. Ali Crum
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Kal Penn / Ed Helms (Podcast Hosts)
Kraken is built to make crypto simple. Buy Bitcoin, ethereum and over 450 other assets in seconds, fast account funding, fast withdrawals and recurring buys. If you want to stay on schedule, simple, secure and trusted for over 14 years, download Kraken on the App Store or Google Play. That's K R a K E N.
Commercial Announcer
Not investment advice advice. Crypto trading involves risk of loss and is offered to U.S. customers excluding New York and Maine through PayWord Interactive, Inc. View legal disclosures@kraken.com legal disclosures, terms and conditions apply. Time for a Sofa Upgrade Introducing Anibe sofas where designer style meets budget friendly prices Every Anibe sofa is modular allowing you to rearrange your space effortlessly. Perfect for both small and large spaces, Anabe is the only machine washable sofa inside and out. Say goodbye to stains and messes with liquid and stain resistant fabrics that make cleaning easy. Liquids simply slide right off. Designed for custom comfort, our high resilience foam lets you choose between a sink in feel or a supportive memory foam blend. Plus our pet friendly stain resistant fabrics ensure your sofa stays beautiful for years. Don't compromise quality for price. Visit washablesofas.com to upgrade your living space. Today sofas start at just $699 with no risk returns and a 30 day money back guarantee. Get early access to Black Friday now. The biggest sale of the year can save you up to 60% off plus free shipping and free returns. Shop now at washablesofas.com offers are subject to change and certain restrictions may apply.
Business Advertisement Narrator
Being a small business owner isn't just a career, it's a calling. Chase for Business knows how much heart and effort go into building something of your own. That's why we make your business growth our priority. Our team takes the time to understand your mission, where you are now, and where you want to go. Our broad range of solutions is designed with you in mind so you can bring your ideas to life. From banking to payment acceptance to credit cards, you can conveniently manage all your business finances all in one place with our digital tools. Looking for tips and advice? Our online resources are always available to give you the solutions you need to help your business thrive. See how your business can go farther with Chase for Business. Learn more@chase.com business chase for business Make More of what's Yours the Chase Mobile app is available for select mobile devices. Message and data rates may apply JP Morgan Chase Bank NA Member FDIC Copyright 2025 JP Morgan Chase & Co.
Kal Penn / Ed Helms (Podcast Hosts)
So let me get this Straight. Your company has data here, there and everywhere, but your AI can't use the.
Dr. Scott Barry Kaufman
Data because it's here, there and everywhere.
Kal Penn / Ed Helms (Podcast Hosts)
Seems like something's missing.
Dr. Scott Barry Kaufman
Every business has unique data. IBM helps your AI access your data.
Kal Penn / Ed Helms (Podcast Hosts)
Wherever it lives to change how you do business. Let's create smarter business. IBM.
Dr. Scott Barry Kaufman
Just to clarify some. I'm understanding this methodology correctly. They were given accurate information about their genetic risk. Right. You didn't have a condition where people were given. Because that'd be interesting too. A condition where people were given the complete opposite of.
Dr. Ali Crum
Yeah, sorry, I didn't explain that. So people.
Dr. Scott Barry Kaufman
That's why I'm just gonna clarify.
Dr. Ali Crum
Yeah, yeah, no, this is good. So we, we had their actual genetic risk, which is actually three types. You're either the risk allele, the protective allele, or the heterozygote, which is sort of right in the middle. And what we did was we took each of those three groups and we randomized them to getting to being told they're either protected or at risk.
Dr. Scott Barry Kaufman
So it wasn't actually accurate for everyone.
Dr. Ali Crum
Some were right. So people who were actually protected, half were being told they were protected and half are being told the exact opposite.
Dr. Scott Barry Kaufman
Gotcha. Yeah.
Dr. Ali Crum
And so then we can kind of. We can look at. If you just compare the people who were told they were at risk versus told they were protected regardless of what their actual genetic risk was. Just that information changed their exchange rate of carbon dioxide and oxygen and carbon.
Dr. Scott Barry Kaufman
Dioxide changed it in a direction consistent with what they were told. Is that the idea?
Dr. Ali Crum
Yeah, exactly. So the belief that. Yeah, the belief that you are, you know, your genes make you less efficient when you exercise, less protective, created that reality.
Dr. Scott Barry Kaufman
That's. I mean, this. I just can't express enough how my mind was when I read, When I, When I read that paper. Yeah, it's amazing. And it just had to be thinking of studies that I want to conduct, you know, because there's. The GWAS approach is now starting to show not great predictability, but that there's something there with like predicting iq, for instance, and academic achievement potential, you know? You know, and it's. You're getting statistically significant effects. It's explaining maybe what, like 2 to 15% of the variance of the outcome. I mean, that's something. And so it makes me wonder, what if you start. What if you tell people their risk for like, iq, for instance, like higher, low iq, does that actually alter the expression of the genes that the GWAS studies are starting to show are relevant? I just think that would be such an interesting study and potentially controversial, I understand, but I'm just very curious.
Dr. Ali Crum
Yeah. And I love that idea. And how far does it go? Right. Again, this was another one of those studies where our effects were very temporary. Right. In part because it was an experimental manipulation. We were deceiving them, some of many of them about their genetics risk and that was important to do for the science. Right. We wouldn't know otherwise. But you know, if you want to do sort of a long term study of like, oh, how does learning that you're, you know, you're all the aggregate of your genes lead you to have high IQ and how might that affect you over decades? Right. Like that would be really interesting. But we got to be careful in, in how, how we, you know, glean that information as, you know, you know, these messages matter.
Dr. Scott Barry Kaufman
That's why I would want to do the studies is, is the way my mind was thinking about it is that can help show, I mean in a way this is a modern day version of the Pygmalion effect. You know, this is like a modern day fancy genetics update on that. You know, is, is, is it a self fulfilling prophecy, our genetic, is our genetic expression the way we think, A self fulfilling prophecy on our genetic expression. But you know, it's to me it's still along the similar lines, you know, totally.
Dr. Ali Crum
I had that same thought as you were sharing your ideas and I think, you know, some of the reviewers on our paper had a similar question which is like, you know, how important is it that this is genetic information? Like, yeah, if, you know, what if it was just like family history or you know, in the Pygmalion study, it was the Harvard aptitude test. Like you know, at that time. That's right. That was really important information that you believed. And in the day of age we're living in, or at least, you know, we were. I think we're changing slowly. But genes are like everything, you know, there's something, it's like, oh, that's just hardwired, right. If your genes, you know, predispose you to something that's meaningful, that's real, but at the end of the day that's just information. Just like some test or you know, your family history or otherwise.
Dr. Scott Barry Kaufman
That's exactly right. Exactly. I want to end this interview by discussing a very fruitful collaboration you've got going with Jar Clifton at University of Pennsylvania. You guys are quite the duo. Him looking at beliefs about the world at large and you obviously having a very illustrious career looking at beliefs and how it can affect physiology. So what does that mind meld look like? I saw that you recently published a paper in the American Psychologist. Is that right? This year?
Dr. Ali Crum
That's right. Yeah.
Dr. Scott Barry Kaufman
I mean, that's like a dream for psychologists to publish in the American Psychologist. So congratulations. It's probably not your first.
Commercial Announcer
Probably not.
Dr. Ali Crum
International Psychologists, but that's a good point.
Dr. Scott Barry Kaufman
That was very American centric of me to say that. Thank you for pointing that out. But have you. Have you been in the American Psychologist before and tell me about this paper a little bit. Yeah.
Dr. Ali Crum
No, that was the first time. Yeah. And thank you for that. I do. You know, I remember reading, you know. You know, the American Psychologist. It has, like, the picture of the Psychologist. I remember reading articles from some of my heroes and that. But yeah, I'm really excited about the partnership that I've started with Jer Clifton. I know you know him from Penn. Both of us share similar Penn roots. Jer is doing really critical work, I think, looking at the beliefs that we hold, the mindsets we hold about the nature of the world as one big place. And, you know, as. Just as I've extended Carol Dweck's work from looking at your core beliefs about intelligence to looking at our core beliefs about other domains like stress or cancer or exercise or diet or our genes. Right. What Jer's doing is looking at what are our core beliefs about the world, Right? Like, do you believe the world is dangerous or safe? Do you believe the world is abundant or scarce? Do you believe the world needs you, Scott Barry Kaufman. Or could it just live without you? You? Right. These are, again, neither true or false, right or wrong. There's lots of evidence to support either side of these spectrums. Spectrum.
Dr. Scott Barry Kaufman
But there's a lot of evidence that. No, sorry, go.
Dr. Ali Crum
The world needs you, Scott.
Dr. Scott Barry Kaufman
You're saying there's evidence for the world don't need me.
Dr. Ali Crum
Yeah, yeah, right. Well, the world. I believe the world needs you. I believe the world needs me. Right.
Dr. Scott Barry Kaufman
I believe that's actually objectively true, though. That's right. That's where I'm disagreeing with you.
Dr. Ali Crum
My mental mindset knows that it's not objectively true, but it is a mindset that serves me and keeps me motivated to do what I can to actually have that be true. But anyways, we did. We got off on a tangent there, but, you know, so Jer's work is. Was really methodologically advanced because instead of just, like, coming up with, you know, the beliefs that he thought mattered about the world, he did decided to take A systematic approach to uncovering what are all the possible beliefs that people could hold about the nature of the world. He looked at, you know, many thousand tweets. He looked at all the great religious texts, philosophical texts, you know, surveys in different countries and so forth. And, you know, I think my contribution to that work has been to kind of help define the type of belief we're talking about here. So these aren't, you know, nuanced kind of, you know, takes on the world that could. Could be falsified, like the world is flat or, you know, the world was made by God. Right. These are simple, adjectival and evaluative beliefs about the nature of the world. And they tend to have these modifiers like it's fixed or malleable, it's enhancing or debilitating, it's abundant or scarce, these adjectives that characterize the essence of what the world is. And in that paper, what was fun to write about with Jer is when it comes to the world, our beliefs are omnipresent, right? Why? Because we never leave the world. At least you and I haven't yet left the world. And so personality psychologists and social psychologists used to get in these epic debates about, like, is it the person, like, is it their personality that's shaping their behavior, or is it the situation?
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Right.
Dr. Ali Crum
And obviously, like, the situation matters. You know, you're level of introversion and quietness is going to differ if you're in a movie theater or a party. But on the whole, you know, whether you're more extroverted is going to shape how talkative you are. But what Jer and I talk about in this paper is that personality, as defined as this is who you are on average, across many different situations, is not. It's here, too, also about a belief about a situation, right. It's in this case, it's a belief about the situation of the world, this place, that you never leave. So that's a little philosophical. But we're doing lots of fun work kind of trying to codify what are these beliefs? How do they matter? Like, what are the mechanisms and what's the role that they play in shaping not just, you know, our health and performance, which has been my focus, but who. Who we are, what are, how we show up in the world.
Dr. Scott Barry Kaufman
It's such deep, deep, profound and important work. Ali, I started off saying, I'm so proud of seeing your. Your journey. I just want to conclude by reiterating that and really view you as, you know, one of the brightest lights in our field in this generation at this time in human history. And I'm honored to be in the world, in the world with you at this time.
Dr. Ali Crum
Thanks so much, Scott. And I really, you know, when I look back at my days in grad school, which were stressful and uncertain and, you know, in many ways research was me search. I started the stress research. During that time. I, you know, having people like you in my life made it possible, made it doable, made it fun. And most importantly, people like you reminded me of why we're doing this. Right? We're not doing it for ourselves. We are doing it for the world. So thank you for the work that you do and all the sincerity and the, you know, really just the kind of joy that you bring to it.
Dr. Scott Barry Kaufman
Thank you. Thanks for letting. Having me remind myself about all that as well is really important as well.
Dr. Ali Crum
So.
Dr. Scott Barry Kaufman
Oh, boy. Thank you so much. And yeah, talk soon.
Dr. Ali Crum
To be continued.
Kal Penn / Ed Helms (Podcast Hosts)
Kraken is built to make crypto simple. Buy Bitcoin, ethereum and over 450 other assets in seconds. Fast account funding, fast withdrawals and recurring buys. If you want to stay on schedule, schedule simple, secure and trusted for over 14 years, download Kraken on the App Store or Google Play. That's K R a K dash E.
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N not investment advice. Crypto trading involves risk of loss and is offered to U.S. customers, excluding New York and Maine through PayWord Interactive Incorporated. View legal disclosures@kraken.com Legal disclosures, terms and conditions apply.
Kal Penn / Ed Helms (Podcast Hosts)
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Kal Penn / Ed Helms (Podcast Hosts)
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Dr. Ali Crum
This is an iHeart podcast.
Host: Dr. Scott Barry Kaufman
Guest: Dr. Alia Crum
Release Date: November 20, 2025
In this episode, Dr. Scott Barry Kaufman speaks with Dr. Alia Crum, a pioneer in the field of mindset psychology. They explore how our mindsets—the lenses through which we interpret information—can fundamentally shape our reality through psychological, behavioral, and physiological mechanisms. Together, they discuss Dr. Crum’s transformative research on the placebo effect, stress mindsets, physiological responses to beliefs about health, and the growing body of work on metacognitive mindset interventions. The conversation weaves through personal stories, landmark studies, and the power (and responsibility) we have in how we choose to view ourselves and the world.
"That class, you know, it didn't necessarily open my mind to things... But it made me feel at home. It made me feel like I belonged." – Dr. Crum (08:22)
"...if we could make them aware...that shift in mindset didn't just change how they felt, but also had measurable changes on their blood pressure, their body fat, their weight, and so forth." – Dr. Crum (10:50)
"...when people thought they were consuming an indulgent shake, their body responded as if they had had more food." – Dr. Crum (14:35)
"People who believe...that stress can be enhancing, they show more adaptive cortisol response. And...more willingness for feedback." – Dr. Crum (28:06)
"By meta mindset, what we mean...is we inspire people to adopt...the mindset that stress can be enhancing not because they're manipulated into it...but because they choose consciously that that mindset is a more useful one to have." – Dr. Crum (43:22)
"When people thought they had the risk allele, they converted oxygen into CO2 in a far less efficient rate... But the physiological results were, were really interesting. And it was fully shaped by belief, not their genetics risk." – Dr. Crum (57:54)
"...our beliefs are omnipresent, right? Because we never leave the world." – Dr. Crum (69:07)
On Beliefs and Reality:
“The world, your beliefs aren’t just sort of a reflection of reality as it is… You kind of sit back and see the kind of absurdity of it all." – Dr. Crum (03:05)
On the Placebo and Potential:
“That was really important...realizing actually the direction in which the belief had an effect.” – Dr. Crum (16:00)
On Stress Mindsets and Motivation:
“If you think that stress is bad for you...you’re stressed about the stress and you’re upset that you’re stressed...the mindset itself just made the stress worse.” – Dr. Crum (28:15)
On Choosing Useful Mindsets:
“You choose, right? Like, how do you want to choose to view stress?...do you want to view it as debilitating or do you want to view it as enhancing?” – Dr. Crum (43:21)
On Cancer Mindsets:
“You have people who have stage 4 metastasized cancer who believe it’s an opportunity...and you have people with stage one...that feel like their whole life’s over. And here again, these mindsets matter.” – Dr. Crum (48:04)
On Genetic Risk Information:
“They converted oxygen into CO2 in a far less efficient rate...it was fully shaped by belief, not their genetics risk.” – Dr. Crum (57:54)
On Self-Fulfilling Prophecies:
“Is our genetic expression...the way we think, a self-fulfilling prophecy on our genetic expression?” – Dr. Kaufman (65:29)
On Global Mindsets:
"What Jer [Clifton] is doing is looking at what are our core beliefs about the world, Right? Like, do you believe the world is dangerous or safe? Do you believe the world is abundant or scarce?" – Dr. Crum (67:55)
The discussion is warm, personal, and intellectually invigorating. Dr. Kaufman and Dr. Crum’s longstanding friendship brings an open, trusting energy. The conversation is a blend of academic rigor, accessible explanations, and authentic reflection, making complex science feel relevant for listeners’ lives.
Both Dr. Kaufman and Dr. Crum reflect on their shared academic journey, the joys and uncertainties of research, and their commitment to using their work for “the world.” The episode’s sentiment is one of curiosity, humility, and hope: we may not control all of reality, but we have astonishing power to shape how we meet it.
This summary captures the heart of the episode for those curious about how beliefs—about everything from milkshakes to mortality—shape our moment-to-moment reality and long-term well-being.