The Skinny Confidential Him & Her Podcast: Featuring Dave Asprey on Effective Biohacking for Enhanced Well-being

Release Date: May 26, 2025

In this compelling episode of The Skinny Confidential Him & Her Podcast, hosts Lauryn Everts Bosstick and Michael Bosstick engage in an in-depth conversation with Dave Asprey, a luminary in the biohacking community. Known as the founder of Bulletproof Coffee and the Bulletproof Diet, Dave Asprey delves into transformative strategies for optimizing health, increasing energy, and mitigating factors that contribute to aging and various health issues.

1. Dave Asprey’s Biohacking Journey

[00:25] Dave Asprey:
"Dave Asprey. He is the founder of Bulletproof Coffee, the Bulletproof Diet, and really the entire biohacking movement. It is so on brand that the father of biohacking is on the him and her show today."

Dave Asprey introduces himself as a pioneer in the biohacking arena, highlighting his achievements as a four-time New York Times bestselling author, CEO of Upgrade Labs, and host of the award-winning podcast Human Upgrade. His extensive background sets the stage for a conversation rich in expertise and practical insights.

2. Overcoming Personal Health Struggles

[01:13] Laurie Everts:
"I was 300 pounds and when I was 14, they said you have arthritis... I just realized I'm eating too much lettuce, or maybe it doesn't work."

Lauryn shares her personal struggle with severe health issues, including obesity, chronic fatigue, fibromyalgia, and high risk of cardiovascular diseases by age 30. Traditional diets and exercise regimens failed her, leading her to explore unconventional methods. Her epiphany came from observing discrepancies in weight despite diet and exercise, sparking her journey into biohacking.

3. The Evolution of Biohacking and Longevity

[05:13] Lauren Everts: "The original definition of biohacking was the art and science of changing the environment around you and inside of you so you have control of your own biology..."
[05:26] Lauren Everts: "I tried every diet. I tried the Zone diet, I tried the Atkins diet..."

Lauren discusses her extensive experimentation with various diets, eventually discovering that optimal intake of animal-based proteins and fats, alongside a controlled approach to carbohydrates, significantly influenced her weight loss and health improvements. She emphasizes the importance of quality protein intake, citing “1 gram per pound of body weight” as a benchmark for satiety and metabolic efficiency.

4. Rethinking Plant-Based Diets and Toxins

[08:05] Dave Asprey:
"What if I laid out a bunch of vegetables?"
[12:08] Lauren Everts:
"Spinach is so full of oxalate. Oxalate is a chelator. It sticks to minerals, stealing them from your bones..."

A significant portion of the discussion revolves around the hidden toxins in commonly lauded superfoods. Lauren challenges the conventional wisdom surrounding vegetables like spinach and kale, explaining how high levels of oxalates can bind essential minerals, leading to deficiencies and health issues such as kidney stones and interstitial cystitis. She advocates for a more selective approach to plant consumption, focusing on lower-toxin vegetables like arugula and romaine.

5. Optimizing Coffee Consumption for Health

[15:22] Dave Asprey:
"How do you consume coffee at this point?"
[15:31] Lauren Everts:
"I always brew my coffee with a metal filter... Danger Coffee has a therapeutic dose of trace minerals and electrolytes."

Lauren highlights the significance of coffee quality and preparation methods in biohacking. She recommends using metal filters to preserve essential coffee oils like cafestrol and kahweol, which have anti-inflammatory properties and beneficial effects on cholesterol levels. Her preferred brand, Danger Coffee, is formulated to be mold-free and enriched with minerals, enhancing both taste and nutritional value.

6. The Role of Meditation and Trauma Healing in Biohacking

[27:21] Michael Bostick:
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[27:31] Lauren Everts:
"I went through this journey where I'm kind of anxious and miserable and angry... it was like an altered state."
[34:10] Lauren Everts:
"I had a traumatic birth... Your nervous system was primed for threats instead of safety."

Lauren delves into the profound impact of meditation and trauma healing on overall well-being. She narrates her transformative experiences with various therapeutic practices, including holotropic breathing and shamanic training. Through addressing deep-seated traumas, especially those stemming from childhood and birth, Lauren emphasizes the importance of emotional regulation and the ability to enter peaceful, empowered states of mind—a core aspect of effective biohacking.

7. Managing Emotional Triggers for Enhanced Performance

[36:37] Dave Asprey:
"If someone's impatient and irritable all the time, how do they get connection? How do they switch it?"
[48:39] Lauren Everts:
"Your chosen state is peaceful and powerful... You reduce the amount of energy you waste on fear."

The conversation shifts to the management of emotional triggers and maintaining a desired mental state. Lauren introduces her Reset Process, a structured meditation framework aimed at identifying and transforming emotional triggers into states of gratitude and forgiveness. By reallocating mental energy from fear and anger to peace and curiosity, individuals can achieve greater congruence between their inner states and outward behaviors, enhancing both personal and professional performance.

8. Optimizing Sleep and Light Exposure

[56:53] Michael Bostick:
"From your perspective, what do you think people are doing to cause issues with longevity?"
[57:11] Lauren Everts:
"Light exposure is a major toxin. The type of light and timing greatly affect sleep quality."
[59:24] Michael Bostick:
Discussion about using TrueDark glasses to block toxic blue light.

Lauren underscores the critical role of light exposure in regulating circadian rhythms and overall health. She advocates for minimizing exposure to blue light from artificial sources in the evening by using specialized glasses like TrueDark, which block harmful wavelengths below 490 nanometers while allowing beneficial blue light during the day. Proper light management not only enhances sleep quality but also supports hormonal balance and cognitive function.

9. Genetics and Personalized Nutrition

[72:23] Michael Bostick:
"So I have a weird genetic background... How do you think genetics play into diet?"
[73:07] Lauren Everts:
"Genetics make a big difference. Figure out what your ancestors ate... Was it rice or wheat?"
[75:43] Lauren Everts:
"Avoid wheat until farming practices improve. Opt for grass-fed meats and fermented foods if possible."

Addressing the interplay between genetics and diet, Lauren emphasizes the importance of personalized nutrition. She advises individuals to consider their ancestral dietary patterns—such as the predominance of rice or wheat—and adapt their modern diets accordingly. Lauren recommends focusing on high-quality, grass-fed animal proteins and incorporating fermented foods like sourdough, which can reduce gluten content and enhance nutrient absorption.

10. Addressing Electromagnetic Fields (EMFs) and Environmental Toxins

[77:22] Michael Bostick:
"What about EMFs?"
[78:06] Dave Asprey:
"TrueDark glasses block toxic blue light, which is beneficial for managing EMFs."
[80:42] Dave Asprey:
"Protect yourself by keeping phones away from sensitive areas and turning off Wi-Fi at night."

The discussion broadens to environmental health, specifically the impact of Electromagnetic Fields (EMFs). Lauren explains how EMFs can disrupt cellular function by affecting voltage-gated calcium channels, leading to cellular swelling and mitochondrial damage. She suggests practical measures such as keeping electronic devices away from the body, using airplane mode, and minimizing Wi-Fi exposure during sleep to mitigate EMF-related health risks.

11. Enhancing Sexual Health and the Wasabi Method

[84:02] Lauren Everts:
"The Wasabi Method involves using shockwave therapy to enhance blood flow and nerve growth in the genital area."
[86:36] Dave Asprey:
"This method can significantly increase penile size and improve erectile function."

Addressing sexual health, Lauren introduces the Wasabi Method, a form of shockwave therapy designed to promote the growth of blood vessels and nerves in the genital region. This technique not only addresses erectile dysfunction but also enhances sexual performance and satisfaction. Lauren shares her personal experiences, noting substantial improvements in size and functionality, thereby underscoring the method's efficacy in biohacking sexual health.

12. Genetic Engineering and Supplements for Longevity

[89:33] Dave Asprey:
"Stop wasting energy on being reactive."
[90:24] Lauren Everts:
"Low-dose nicotine and optimized supplements like glutathione support cognitive and physical health."

In the latter part of the episode, Lauren discusses advanced biohacking techniques involving genetic engineering and supplementation. She advocates for the use of low-dose nicotine as a cognitive enhancer and discusses the importance of supplements like glutathione for liver protection and detoxification. The conversation also touches on innovative products such as Zbiotic, a genetically engineered probiotic that mitigates the negative byproducts of alcohol consumption, thereby supporting liver health and reducing hangover effects.

13. Final Thoughts and Book Promotion

[95:07] Dave Asprey:
"Tell us where we can get a code for the coffee and the glasses and what the URLs are."
[95:17] Lauren Everts:
"Use code skinny at dangercoffee.com and truedark.com for special discounts."
[95:48] Lauren Everts:
"My new book 'Heavily Meditated' comes out in May. Available wherever books are sold."

As the episode concludes, Lauren promotes her upcoming book, "Heavily Meditated," scheduled for release in May. She invites listeners to purchase it through standard book retailers, emphasizing its relevance to the topics discussed. Additionally, she offers exclusive discounts on her recommended products—Danger Coffee and TrueDark glasses—using the promo code SKINNY at their respective websites.

Key Takeaways:

• Personalized Nutrition: Tailor your diet according to genetic predispositions and ancestral eating patterns, focusing on high-quality animal proteins and minimizing plant toxins.
• Optimized Coffee Consumption: Use metal filters and mineral-enriched coffee brands to maximize health benefits and reduce negative side effects.
• Emotional and Mental Health: Implement structured meditation practices to manage and transform emotional triggers, fostering a peaceful and empowered mental state.
• Light and Sleep: Regulate light exposure using specialized glasses to enhance sleep quality and support circadian rhythms.
• Environmental Health: Minimize EMF exposure by managing electronic device placement and usage, especially during sleep.
• Advanced Biohacking Techniques: Explore innovative methods like the Wasabi Method for sexual health and consider supplements and probiotics that support longevity and cognitive function.

This episode provides a wealth of actionable insights for listeners interested in biohacking and enhancing their overall well-being. Dave Asprey’s expertise, combined with Lauryn and Michael’s engaging dialogue, offers a comprehensive guide to navigating the complexities of modern health optimization.

Notable Quotes with Timestamps:

• Lauren Everts [01:13]:
  "I was 300 pounds and when I was 14, they said you have arthritis... I just realized I'm eating too much lettuce, or maybe it doesn't work."

• Lauren Everts [08:05]:
  "Spinach is so full of oxalate. Oxalate is a chelator. It sticks to minerals, stealing them from your bones."

• Dave Asprey [15:22]:
  "How do you consume coffee at this point?"

• Lauren Everts [34:10]:
  "You come into the world and something's trying to kill you... you will carry that with you until you do the work."

• Lauren Everts [48:39]:
  "Your chosen state is peaceful and powerful... You reduce the amount of energy you waste on fear."

• Lauren Everts [56:53]:
  "Light exposure is a major toxin. The type of light and timing greatly affect sleep quality."

• Lauren Everts [84:02]:
  "The Wasabi Method involves using shockwave therapy to enhance blood flow and nerve growth in the genital area."

• Lauren Everts [89:33]:
  "Low-dose nicotine and optimized supplements like glutathione support cognitive and physical health."

This episode stands out as an essential listen for anyone keen on leveraging biohacking techniques to achieve optimal health and longevity. Whether you're new to the concept or a seasoned practitioner, Lauryn, Michael, and Dave provide valuable perspectives and practical advice to elevate your wellness journey.