The Skinny Confidential Him & Her Show

Episode: The Glucose Goddess Jessie Inchauspé on The Truth About Blood Sugar, Energy, & Managing Cravings

Date: March 9, 2026
Guests: Jessie Inchauspé (Glucose Goddess)
Hosts: Lauryn Evarts Bosstick & Michael Bosstick

Episode Overview

In this highly requested episode, Lauryn and Michael sit down with Jessie Inchauspé (aka the Glucose Goddess), a renowned French biochemist and best-selling author. Jessie is devoted to translating the cutting edge of glucose science into actionable, everyday tips for better physical and mental health. The conversation ranges from managing energy and cravings, glucose's impact on pregnancy and child development, to busting nutrition myths and offering approachable blood sugar hacks for all stages of life.

Key Discussion Points & Insights

1. Food Environment: France vs. USA

[01:31-03:00]

• Jessie, as a Parisian, describes how eating healthy is much easier and more affordable in France compared to the U.S.
• "In France, it's cheap to eat healthy. ... Here, it's a trek. I have to go to Whole Foods to get the nice produce. And things are way more expensive." (Jessie, 01:38)

2. Eye-Opening Glucose Discoveries

[03:20-04:27]

• Most mind-blowing finding: The order in which you eat your food dramatically affects glucose response.
  • Eat veggies first, then proteins/fats, then starches/carbs = smaller glucose spike.
  • "Veggies first. I need to make like a T-shirt that says that." (Jessie, 04:03)

3. The Impact of Pregnancy Diet

[04:27-06:42]

• What you eat during pregnancy can shape your baby’s brain, body, and lifelong health—DNA is not the only factor.
• Example: Baby A (with prenatal choline, omega-3s, low sugar) has better IQ, coordination, and lower diabetes risk than Baby B (nutrient-poor, high sugar diet).
• Jessie’s new book focuses on practical guidance for pregnancy nutrition.

4. Unpacking Glucose & Spikes

[07:47-11:18]

• Glucose = body’s primary energy source, supplied mainly by carbs (starches & sugars).
• Glucose spikes result from eating too many carbs/sugar at once—leads to inflammation, weight gain, fatigue, and faster aging.
• "With every glucose spike, you're aging faster." (Jessie, 10:19)

5. Glucose Monitors: Why & How

[11:18-12:37]

• Jessie and Michael discuss wearing continuous glucose monitors for real-time feedback.
• Glucose crash after a spike explains many cravings and mid-day fatigue.

6. Hacks to Manage Glucose

[12:15-18:05]

• Pair carbs/sugar with protein, fat, or fiber: e.g., eat almonds with sweets to slow glucose spikes.
• Alcohol: Wine alone doesn't spike glucose, but cocktails with added sugar do.
• Vinegar: A tablespoon before a carb meal can reduce the spike by up to 40%.
  • "Vinegar contains this magical molecule that slows down how quickly carbs turn to glucose." (Jessie, 17:44)
• Move after meals: Walking or doing mild exercise helps lower glucose.

7. Kid & Family Strategies

[18:05-19:07, 50:23-51:08]

• Give kids veggies before dinner or snacks to start with fiber.
• Replace sugary juices with whole fruits; avoid fruit juices and smoothies.
• "Veggies first, move after eating, put clothing on your carbs." (Jessie, 18:32)

8. The Personal Story: Why Glucose?

[27:04-30:05]

• Jessie’s health struggles after a back injury included severe mental health symptoms, only improving after glucose monitoring revealed that spikes triggered her episodes.
• Led to her passion in researching and teaching about glucose management.
• "Nobody ... ever said look at your diet, ever. ... Thank you, universe, for showing me this." (Jessie, 29:10)

9. Mental Health & Blood Sugar

[35:15-35:47]

• Studies show more glucose spikes correlate with increased depression and anxiety symptoms.
• Low glycemic (glucose-steady) diets help people report fewer mental health symptoms.

10. Food Myths & Practical Application

[36:01-40:18]

• Fruit: Whole fruit is fine, juice/smoothies spike glucose.
• Most supermarket fruit is much sweeter than wild/ancestral varieties.
• "All the fruit in the supermarket today has been bred for centuries to make them super sweet and juicy." (Jessie, 39:06)
• "If you do like a vegetable juice, it's fine, because vegetables don't contain sugar." (Jessie, 40:03)

11. Veganism & Nutrient Gaps

[41:25-42:06]

• Vegan isn't automatically healthy; many vegan foods are highly processed and sugary.
• Prioritize protein, omega-3s, whole foods.

12. Fundamental Glucose Tips

[42:27-43:02]

• Focus on proteins, healthy fats, veggies; eat carbs strategically.
• If Jessie could change one thing: eliminate sweet breakfasts in favor of protein-rich ones.
• "I'd replace all of those with an omelette." (Jessie, 43:16)

13. Pregnancy Nutrition Pillars (as in Jessie’s upcoming book)

[51:10-53:43]

• Choline: Key for brain development (eggs, liver, meat, fish).
• Protein: Critical for building baby's body (>1.5g/kg/day in later trimesters).
• Omega-3 (DHA): Boosts child’s IQ.
• Sugar: Intake passes directly to the fetus—spikes in mom = spikes in baby.
• Dispelling myths: Pregnancy diet does matter, baby does not always get needed nutrients.

14. Common Misconceptions About Jessie’s Work

[54:59-55:42]

• Jessie is not anti-sugar, nor is her approach about restriction.
• It’s about balanced, sustainable strategies—not eliminating the foods you love.

15. GLP-1 Drugs & Weight Loss

[55:42-57:01]

• GLP-1 (weight-loss) drugs curb hunger but don’t solve underlying food quality issues.
• "It's kind of like ... our solution is not to clean the water, but to give people a drug that makes them less thirsty." (Jessie, 55:49)

16. Glucose Management & Weight/Fat Loss

[57:38-58:59]

• Stabilizing glucose leads to fewer cravings and helps release stored fat.
• "Naturally ... when you have high glucose levels, your body is in fat storage mode." (Jessie, 58:19)
• Side effect—not main goal—of glucose hacks: losing excess weight.

Notable Quotes & Memorable Moments

• On the importance of eating order:
  “Start with the veggies. ...They create this sort of protective mesh in your intestine that slows down the arrival of the carbs in your bloodstream.” (Jessie, 04:03)

• On mental health and glucose:
  “Big glucose spikes could trigger these episodes of depersonalization. ...Nobody ... ever said look at your diet, ever.” (Jessie, 28:44, 29:10)

• On fruit myths:
  “All dogs have been, quote unquote, engineered by humans. Fruit is the same. ...All the fruit in the supermarket today has been bred for centuries ... to make them super sweet and juicy.” (Jessie, 38:52, 39:06)

• On pregnancy diet's power:
  “Your baby's body and brain is shaped by your pregnancy diet. Same DNA, but two different diets will give birth to two different babies.” (Jessie, 04:28)

• On balancing enjoyment and strategy:
  “It's not like you're telling people ... not to eat the donut. No, you're just saying have a strategy around the donut.” (Lauryn, 33:10) “I want to control my donuts. I don't want the donuts controlling me.” (Jessie, 33:28)

• On GLP-1 drugs:
  “It’s like ... if the water was toxic and our solution was not to clean the water, but to give people a drug that makes them less thirsty. That is literally what's going on with food.” (Jessie, 55:49)

• On child behavior & food:
  “I've talked about this on the show, but [kids] come home after a birthday party and they're maniacs ... because they've had the birthday cake and pizza ... Now I'm going to be more strategic with giving them veggies and protein before.” (Lauryn, 50:23)

Handy Timestamp Reference

• 01:38: Jessie on the French food environment
• 03:20: The shocking research on eating order and glucose spikes
• 04:27-06:42: Pregnancy diet shapes baby’s lifelong health
• 07:47: “Glucose” explained in everyday language
• 10:19: “With every glucose spike, you're aging faster.”
• 12:15: Why pair sweets/carbs with protein/fat
• 17:44: Vinegar hack for lowering glucose spikes
• 27:04-30:05: Jessie’s personal health journey: back injury to glucose science
• 35:15: Connection between glucose spikes & mental health
• 39:06: Modern fruit is much sweeter than ancestral/wild types
• 51:10-53:43: Four pregnancy nutrition pillars
• 55:49: GLP-1 drugs analogy

Practical Blood Sugar Hacks from Jessie

• Veggies first: Start every meal with vegetables (fiber protects against spikes)
• Eat proteins/fats before starches/carbs
• Pair carbs or sweets with protein/fiber/fat
• Vinegar: 1 tbsp in water before carbs = up to 40% lower spike
• Move after meals: Take a walk to use up circulating glucose
• Avoid sweet breakfasts: Switch to protein-based (e.g., eggs)
• Whole fruits over juice/smoothies
• For kids: Prep veggies/raw snacks before main meal; teach them to pair sweet treats with nuts or cheese

Jessie's New Book

Title: The Nine Months That Count Forever: How Your Pregnancy Diet Shapes Your Baby’s Future
Release: March 2026; Available for preorder.
Covers everything discussed on pregnancy diet pillars.

Connect with Jessie

• Instagram: @glucosegoddess
• Website/book: Glucose Goddess

This episode is an essential guide to making glucose management approachable and impactful for everyone—from parents and fitness enthusiasts to anyone seeking better energy, mind, and long-term health. Jessie’s perspective is warm, practical, and evidence-based, making complex science not only accessible but empowering—no food shame required.