Podcast Summary: The Spiritual Hustler

Episode: Peptides, GLP-1s and How to Reinvent Yourself with Stephanie Gambetta

Host: Jessica Zweig
Guest: Stephanie Gambetta
Date: December 23, 2025

Episode Overview

This episode features an inspiring and deeply personal conversation between Jessica Zweig and Stephanie Gambetta—health coach, founder of The Loopway, and podcast host. The central theme is personal reinvention, focusing on embracing authentic alignment, overcoming limiting beliefs, and leveraging scientific wellness tools (namely, peptides and GLP-1s) to support a vibrant life. The discussion intertwines entrepreneurship, spirituality, optimal health, and the power of sisterhood and quantum healing.

Key Discussion Points and Insights

1. Stephanie’s Transformation Journey & Claim Your Light Retreat

• Origin Story: Stephanie recounts shortly before joining Jessica’s retreat, she was at a crossroads feeling uncertain and out of alignment in her career and life.
  • "I was coming in with a decision I wanted to make. Did I want to launch this coaching business...?" (10:54)
• Catalyst for Change: The investment and energy required to join the retreat drew her to seek out other women on the same path.
• Breakthrough Moment: A transformative breathwork session at the Mexico retreat led Stephanie to release deep-seated shame, pain from her divorce, and guilt toward her children.
  • "I started visualizing... my children... my girls... and I'm telling them I'm sorry that I got divorced... and they were the opposite. They were like, oh my gosh mom... we're brave, we're here." (17:21)
  • Experienced a multidimensional, almost ancestral healing: Stephanie felt her late grandmother's presence urging her to "stop playing small" and step fully into her voice. (19:24)
• Post-Retreat Shift: Stephanie became physically ill after the retreat—interpreted by another attendee as her body "catching up to where your soul went." This led to a rapid download that birthed her business, Loop. (24:00)

2. Birthing the Loopway: Business From Authentic Alignment

• Logo & Meaning: Loop’s infinity logo symbolizes life’s flow and ongoing transformation.
• Rapid Growth: In under 8 months, Loop scaled to a team of 10, launched a supplement line, and became a sought-after platform for peptide-based health coaching. (30:32)
• Alignment as the Engine: Stephanie credits alignment and releasing self-doubt (not giving a f*ck) as her primary strategy for business acceleration.
  • "That's the strategy. Not caring. Just going for it." (35:28)
• Role of Sisterhood: Several major collaborators and team members were women she met at Jessica’s retreat, highlighting the power of intentional networking and authentic community.

3. Redefining Success and Hustle After 50

• Breaking Age Stereotypes: Stephanie started this chapter at 50, debunking the myth that it’s “too late” to begin again.
  • "Every one of us feels at some point... that it's too late... and the fact that you decided to double down on your innate design at 50 is inspiring..." (41:31)
• Public Presence: From an extremely private Instagram account and reluctance to share, Stephanie now embraces visibility, leveraging podcasts and social media as tools for her mission.

4. Science & Business of Peptides and GLP-1s

• Peptide Education: Peptides = short chains of amino acids; the body recognizes and uses them to optimize function, rather than simply replace what is missing (like traditional meds).
  • "A peptide goes and says, okay, what receptor is this supposed to stimulate and put to work? ...it enhances and optimizes what you already have in your body." (48:00)
• GLP-1s (e.g., Ozempic, Wegovy):
  • Get negative press due to abuse and improper dosing, but can be life-changing for weight management, insulin resistance, inflammation, and even brain health.
  • Stories: Jessica shared how microdosing GLP-1s helped her mother reverse prediabetes and her own journey overcoming years of inflammation. (51:24)
  • Stephanie explained the risk of high dosages and the medical system’s short appointments, advocating for careful, individualized care.
    • "They're not putting the lifestyle together that you need to add to the GLPs... they're like 'oh, it's not working? Take more.' " (49:37)
  • Beyond weight loss: Use in autoimmunity, mental clarity, and as a tool (not a crutch)—"it's a tool. It's no different than a personal trainer or a chef or taking B12... it's just a tool." (54:48)

5. Loop’s Business Model

• Stephanie is the coach and public face; licensed medical providers on her team handle client plans, bloodwork, and telehealth oversight—marrying AI and hands-on medical expertise.
  • "AI is reading the blood work and AI is creating your peptide plan with marrying your goals... but the doctor path is really the way to go because there's a human component..." (43:44)
• Education-first approach: Website includes an AI-driven educational portal; access for those unable to afford full coaching.

6. Mindset and Metaphysics—Operating in “Quantum” States

• Quantum Leap: Stephanie attributes the acceleration of her business and fulfillment to surrendering control, operating from intuition and energetic alignment.
  • "You came in wanting one thing and then the universe gave you what you really needed..." (22:17)
  • "You're in alignment... you're in your highest timeline..." (65:50)
• Community & Frequency: The retreat, breathwork, and subsequent business reflected Stephanie’s shift from logic/linearity to multidimensional, intuitive living.
• Feminine Power: Jessica and Stephanie discuss reclaiming feminine flow as a source of business creativity, having spent years in a more masculine (forced hustle) paradigm.

Notable Quotes & Memorable Moments

• On embracing public presence:
  "I just stopped caring. Which is a strategy."
  – Stephanie Gambetta (35:28)

• On rebirth during breathwork:
  "When you sat up from that breathwork session, it's the woman that I'm looking at right now... you were being reborn."
  – Jessica Zweig (21:14)

• On getting started at 50:
  "At its core... the strategy is unapologetically zero f*cks given—living your light, being in alignment as yourself. And you can create and manifest and expand anything from that place."
  – Jessica Zweig (57:43)

• On mission and feminine leadership:
  "My boyfriend... I love my relationship with you because I can be so feminine. In my marriage, I had to be so masculine."
  – Stephanie Gambetta (64:36)

• On judgment and GLP-1s:
  "What's the difference if someone wants to lose 5 or 10 pounds versus 40? You still don't feel good in your jeans."
  – Stephanie Gambetta (55:07)

• On quantum possibility:
  "The generations of women that came before us... we are doing it for them. We're walking the path that they had to endure that we now get to thrive in."
  – Jessica Zweig (25:31)

Timestamps to Key Segments

• Stephanie’s Breathwork Breakthrough (Retreat Experience): 13:05 – 22:20
• Starting Loop & Business Insights: 24:53 – 35:28
• Scaling Rapidly & Letting Go of Perfection: 35:28 – 42:38
• Clarifying Loopway’s Telehealth Model: 42:45 – 45:30
• Peptides & GLP-1s Explained: 47:55 – 56:00
• Mindset for Reinvention & Advice at 50: 57:43 – 66:10
• Future of Wellness & Final Reflections: 65:50 – 67:01

Episode Takeaways

• True transformation—both spiritual and professional—requires radical authenticity and self-trust.
• Age is not a barrier; reinvention is always available no matter the timeline.
• Peptides and modern telehealth (when applied with integrity and personalization) are powerful tools for healing and empowerment.
• Sisterhood, community, and aligned frequency accelerate results beyond linear planning.
• The “new hustle” is rooted in meaning, healing, feminine flow, and quantum trust—leading to lives and businesses that thrive.

Further Exploration

• Connect with Stephanie: The Loopway Website
• Jessica Zweig: Instagram, Podcast
• Listen to full episode for extended stories and technical guidance on peptides and personal branding.