
Hosted by The Tell-Tale Heart: The Pharmacist's Cardiovascular Digest · EN

Learn more about the OCEANIC-STROKE trial here.

In this Heart Month solo episode of the Tell-Tale Heart podcast, host Craig Beavers, PharmD, FACC, FAHA, FCCP, BCCP, BCPS-AQ Cardiology, CACP, examines the “hypertension control paradox” outlined in a recent New England Journal of Medicine perspective, exploring why blood pressure control in the United States remains suboptimal despite effective therapies and long-standing clinical guidelines. Beavers reviews national trends showing stalled progress in hypertension control and contrasts them with higher-performing systems that rely on protocol-driven, team-based care models.

Learn more about the POLY-HF trial here.You can reach the guests on this episode here:Nick Miller, PharmD, on LinkedInNick Miller can be reached at nick@rxcompound.comAmbarish Pandey, MD, on LinkedIn

Join us for a deep dive into hypertrophic cardiomyopathy (HCM) with Andrew Williford, PharmD, an assistant professor and cardiology specialist at UC San Diego Health. In this episode, we break down the genetics, diagnosis, and clinical impact of HCM, explore how management strategies have evolved, and discuss the emerging role of cardiac myosin inhibitors in treating obstructive disease. Dr. Williford also shares insights from his telehealth GDMT titration clinic and offers practical guidance for pharmacists encountering HCM across care settings.Show notes: Hypertrophic Cardiomyopathy Guideline Hub Aficamten or Metoprolol Monotherapy for Obstructive Hypertrophic Cardiomyopathy Mavacamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

Happy New Year from The Tell-Tale Heart! We'll be back in 2 weeks with a new episode. In the meantime, check out the recent episode of Drugstore Dialogue with host Barry Newman, who spoke with Craig Beavers about cardiology pharmacy.Listen here: https://www.spreaker.com/episode/dr-craig-beavers--67706988

In this episode, host Craig Beavers sits down with Marc Baines, cofounder and executive director of the HeartLife Foundation, to explore heart failure care through the lens of lived experience. Diagnosed with heart failure at just 23 years old, Baines shares his path from sudden diagnosis to heart transplant and the critical role pharmacists played as consistent, trusted members of his care team. From medication education and adherence to quality-of-life conversations and continuity across care settings, this discussion offers pharmacists practical insights into how their everyday interactions can profoundly shape patient outcomes, empowerment, and long-term cardiovascular care.Have feedback on this episode or ideas for future topics you’d like us to cover? Let us know—we’d love to hear what matters most to your practice. Email AAntrim@pharmacytimes.com with your feedback and ideas!Show notes:· Learn more about the HeartLife Foundation

In this solo episode, Craig Beavers breaks down new data from the CELEBRATE STEMI trial and the POLY-HF polypill study. He highlights what these findings could mean for real-world practice, from early antiplatelet strategies to improving adherence and outcomes in heart failure. Show Notes: Patient Perspectives on a Polypill Strategy for Heart Failure with Reduced Ejection Fraction: A Convergent-Parallel Mixed Methods Study Embedded in a Randomized Clinical Trial Zalunfiban at First Medical Contact for ST-Elevation Myocardial Infarction

This week, host Craig Beavers spoke with Joe Sassine, PharmD, BCPS, BCACP, CLS, about several key trials presented at the American Heart Association 2025 Scientific Sessions.Show notes: VESALIUS-CV trial: https://www.nejm.org/doi/full/10.1056/NEJMoa2514428 CORAL REEF trial

Studies discussed in today's episode: POLY-HF Trial CELEBRATE Trial VESALIUS-CV Trial

The articles discussed in this episode: The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction: A Novel Framework to Explain Pathogenesis and Guide Treatment Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology