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You will be wasting your money if you are using GLPs for weight loss or you're using it at a higher dose if your thyroid and your hormones are not getting optimized. Welcome to the Thyroid Fixer podcast where we dive deep into the world of thyroid and hormones. Especially for you ladies navigating perimenopause and menopause, and really for anyone struggling with hypothyroidism. I'm your host, Dr. Amy, thyroid and hormone specialist and CEO of Global Telemedicine practice, where we prescribe the right thyroid treatment and bioidentical hormones to all 50 states and most of Canada, helping you become that badass human that you're meant to be. So if you're battling weight gain and hair loss, you can't lose weight no matter what you do, your energy levels are plummeting and your libido left town. Then you're in the right place and you have found your tribe. Remember, I want you to embrace every inch of that badass woman that you truly are. So if you're ready to dive in and fix things, let's get started. Did you know there's a reason why boosting NAD can actually make us feel years younger? This vital NAD molecule powers cellular energy, it supports our DNA health, it aids in detoxification, and it helps your body remain youthful. But by the age of 50, which I'm there now, NAD levels dropped to half of what they were at 20. So, yeah, we need to replace them because I want to feel and look like I'm 20. All right, maybe 30. So luckily there is Qualia NAD Plus, a clinically proven cutting edge supplement that can boost your NAD levels by 67%. So no shots, just a pill. Works amazingly, contains powerful precursors like niacin, niacinamide and niagen. And the top NAD boosters known to science, along with 11 other key ingredients to support the body's entire NAD production process. It's vegan, non GMO, gluten free, so no worries there. And it's a clinically proven formula that has become my go to for maximizing my NAD levels because I want to anti age. So if you want to age well, too high NAD levels are a must. So you're going to visit qualia life.com I'm going to spell that for you. Quote a l I a l I f e.com Thyroid to try Qualia NAD backed by a 100 day money back guarantee. What? Yeah, they back their products. It's going to work, people. So you're going to use the promo code thyroid for 15% off. So that's qualife.com forward slide. Thyroid with the promo code thyroid for 15% off. I completely and totally hear you and I see you and I understand you and I know exactly where you're at. You're gaining weight. You can't lose. You have all the symptoms that no one's listening to. The fatigue, the hair loss, the brain fog. You can't remember why you walked into a room. You don't want to get dressed and go out because you know if you have that glass of wine with your friend and if you have that dessert with your husband or even order an appetizer, you're going to be five pounds heavier the next day and your clothes are already tight. Every single doctor is telling you that you're normal and everything is fine. You've been to multiple conventional medicine doctors trying to use your insurance, hoping to God that somebody has an answer. Then you've dropped thousands of dollars on functional medicine or integrative medicine, because you keep hearing how functional medicine gets to the root cause of the problem. But not every functional medicine practitioner knows the thyroid and knows the hormones and can treat you as a nuanced, personalized individual, a unique person. That is exactly what my team and I do. We specialize in thyroid problems. We specialize in hormones. You can't do one without the other. You cannot just see someone for your thyroid and have them ignore your hormones or have them half ass your hormones. They better be a hormone and thyroid expert. If you are going to spend your time, your energy and your money, if you are going to invest in functional medicine. They need to be a thyroid and hormone expert and treat you as an individual. They can't have a cap on how much T3 that they're going to give you. They have to personalize your treatment plan to get you feeling your best, no matter what that looks like. So that every system in your body functions at the very top, at the very best. And that is exactly what we do. I made it my mission because I went through this. I was dismissed, I was gaslit, I was misdiagnosed, and I dropped thousands of dollars before I found an answer. That is why I made it my mission to be able to treat people in all 50 states so we can prescribe via telehealth. Thyroid and hormones and peptides. Yeah, the GLPs as well, to all 50 states, most of Canada and now Puerto Rico. That is my mission to be able to help you wherever you are, because I want you Living your best life. I want you to join me in optimization land, where you can go out and love life and go out with your friends and go out with your partner and not gain weight looking sideways at a brownie. Yes, we do have financing options available. I'm talking like 0% or 12 months, the whole thing, based on your credit score. We got you. And our programs are affordable. They're completely and totally affordable and they will get you from point A to point B. They will bring you into optimization land. So please don't waste another moment struggling, please. I want you living here with me, a great, happy life in optimization land. So go to my website@dramy.com, click the Become a patient button so we can have a chat. Let's talk it out. Let's hear what you've done, what you haven't done, what's worked, what hasn't worked, and let's get you on the right path to feeling your absolute best. If you can imagine the best life ever, that is absolutely possible for you. I'm not BSing you. I am not BSing you. I was in your shoes. Many of my patients have been in your shoes. We will get you there and that is my promise to you. This is going to ruffle some feathers, but GLPs are a complete waste of money. If you're not doing this, what is this? Well, I'll get to that in a moment. Let's first review GLPs. Glucagon, like peptides, or they're broadly referred to as GLP1s. And if we really get down the nitty gritty when we're talking about Tirzepatide or retatrutide, Those are actually GLP2, GLP3, GLP4s, but we're just going to blanket statement all of them as GLP is. Now, this could be compounded ones that you're receiving from a compounding pharmacy. This could be the prescription. GLP is like Manjaro zempic trulicity and they all have huge, I mean, honestly, huge benefits when used properly. Now, they're quite often used improperly at very high doses, which produces a lot of side effects, including the loss of lean muscle tissue. Lean muscle mass, you will lose your muscle and you will lose your facial fat and start to look like Skeletor. If you high dose these GLPs, if you're not dosing them properly, you will get side effects. And you're also more susceptible to the side effects of gastroparesis, massive constipation, even if it doesn't completely shut down your bowels, massive constipation, and really a multitude of other side effects like nausea, extreme fatigue, hair loss. If you are using these GLPs at too high of a dose because you just want that weight loss, but along with that weight loss comes vital muscle loss, along with things that you really don't want, like hair loss, facial fat loss, all the things right when used properly. And we talk a lot about microdosing when used properly, even if it's at a standard dose. If you're using it to lower your A1C, you're using it for weight loss. And maybe you're at a minimal standard dose. Let's take Tirzepatide. You're rolling in at 5 milligrams. You could still get the side effects with that. But oftentimes if you're metabolically broken, we want to add that in because our target is lowering that a 1C. Now I'm going to tell you a quick story because even those who have been prescribed a GLP one, or maybe you decided to start there, you got roped into one of those online weight loss programs, right, that are promising, you will ship the GLP is right to your door and that's all you need to do. And just pay our monthly fee. I get that, but it has to come with proper education because they'll take your money but they may not educate you. You will be wasting your money if you are using GLP for weight loss or you're using it at a higher dose if your thyroid and your hormones are not getting optimized. So here's the story. Ms. Barbara. Barbara's a patient, amazing woman. She has completely turned her life around going through our program. But she came in on a prescribed GLP1 for her elevated A1C. She was full blown type 2 diabetic, full blown. Her A1C was like an 11, 11.4, something like that. Crazy high. And just for reference, for anyone listening, your A1C optimal really should be between a 4.8 and a 5.2. So she's rolling in screaming high. She's been diagnosed type 2 diabetic, easily 150 pounds overweight. And she was on Ozempic. Her insurance covered it because of her elevated A1C. Her doctor prescribed it wasn't working. Was not working. She was on it for over a year now. Luckily for her, she had a low copay, but still a copay nonetheless. And it wasn't doing anything. Many people are paying out of pocket for these GLP1 programs and not noticing anything. And I'm going to give you this secret right now to make that GLP1 work, because this is what Barbara did. She got her thyroid optimized. Barbara came into the program with an elevated reverse T3. She was on thyroid medication, of course. She was on T4 only. We've already discussed how T4 only does not work. And it did nothing for her except increase her reverse T3. This put her body in survival mode, so it locked her down. There's no way a GLP1 is going to work if your reverse T3 is elevated and you're not on T3. If you are on T4 only and you're tossing in a GLP, just take your money to Vegas and give it to the dealers, put it in the slot machine. Nothing's going to come back. The house always wins. Or go outside in your yard and just set it on fire. Because that's pretty much what you're doing when you purchase a GLP and you don't address your thyroid and your hormones. I'll get to Barbara's hormones in a moment. First of all, we had to lower her reverse T3. We had to reduce the amount of T4 she was on because her doctor had her on 112 milligrams or micrograms. And T4, oh, my God, it never, ever works. T4 only does not work. 98% of us. And I argue that I would bring it up to 100%, but the stat from the American Academy of anti Aging Medicine, A4M claims that 98% of us need T4 and T3 or T3 only. Only 2% do well on T4 only. I haven't found that 2% population. I know a couple people that are on T4 only that they're doing okay. They probably would do a little bit better if we threw in some T3. But let's just say, all right, let's bring it up to 99.9% of people need T4 and T3 or T3 only. So Ms. Barbara, she didn't have that. She was on T4 only. It wasn't working, was driving up her reverse T3 and putting her body in survival mode. So obviously, step one, we started there. Let's get her on the right thyroid medication for her body. And what we're seeing in her labs, well, that helped tremendously. But at the same time, we also addressed the fact that this woman was in menopause and no one was giving her hormones. All of her hormones were Low estrogen, progesterone, testosterone across the board. Now all of your sex hormones also play a role in your body composition and in your insulin and glucose regulation. So the thyroid is going to have a basically dictate whether or not your A1C will be high, dictate whether or not you're going to have control over your glucose, dictate whether or not you are insulin resistant or leptin resistant. And here comes in the hormones as well. Progesterone helps us convert T4 to T3. Progesterone helps with insulin resistance. Testosterone is our get shit done hormone and controls your body composition, you, your ability to burn fat or gain muscle and estrogen. Ladies, when your estrogen tanks and your FSH climbs above a 25, you better just count on your midsection widening. So all of those factors were at play for Barbara and this is why her GLP1 did not work. So this is something crazy that I learned about electrolytes that I did not know before. Low sodium diets, you know, when you cut back on your salt, can actually contribute to insulin resistance. So number one, we don't want that. We know that is going to definitely increase our weight. Low potassium status suppresses your growth hormone, your anti aging hormone, and that even just having low thyroid function disrupts your electrolyte excretion. So I mean, if your magnesium is low, we know that that's going to interfere with thyroid T4 to T3 conversion. Now you have this whole electrolyte excretion issues that you're pushing out more electrolytes, but you need to keep them in for that conversion. I'm telling you the data is crazy on the importance of electrolytes. So I use the OG of electrolyte powders, element number one because they taste absolutely freaking amazing. I want to use probably too many packets in a day, quite honestly, because I keep putting them in my water because they taste that good. But of course I also know that I'm getting my balance of electrolytes and in the summer I need more. Even in the winter when I'm skiing and snowboarding, I'm sweating that all out. You need more. So if you want to try some of these amazing, just amazing electrolytes and actually feel the difference, I mean, you will feel the difference, you'll feel more energized, you won't cramp up and you will get better sleep with this as well. I'm telling you, definitely better sleep. Go to drinklmnt.com so spell out drink-I n k l M-N-T.com thyroid and this is going to save you some money. You can get the sample box, you can try all the different flavors. My absolute favorite. Just side note, grapefruit and orange drink. Elementi.com thyroid. You have to start with the thyroid because again, just as a reminder, and I know many of you know this because you've been listening to me for a while, the thyroid is the master gland. It's the master gland. So I just got done saying it controls your glucose, it controls your insulin, it controls your A1C. It controls your sex hormones. So you can actually go into early menopause when you don't address your thyroid. So thyroid and hormones done at the same time, optimize both of those. And then guess what happened to Barbara. Her A1C went down to a 5.4, which is her diabetes was gone. That's a complete reversal of her type 2 diabetes. Now she continued on the GLP1, but she was actually getting some bang for her buck. It was working. So the GLP1 was working in conjunction. Now instead of just sitting there doing nothing for a year like it was before, it was working in conjunction with her body with the optimized thyroid. With lowering of her reverse D3, with increasing her free T3, with increasing all of her sex hormones, now she was able to lower her A1C and completely and totally reverse her diabetes. Now she was able to lose over a hundred pounds. I'm not quite sure where she's at right now. Maybe she did hit 150. I'll double check with Barbara, but she looks like a completely different woman. She took at least 15 years off of her face. She reverse aged, she lowered inflammation, she reversed her diabetes, but none of that was happening even with the power of a GLP1. And she was on a high dose, people. She was on a high dose glp. She wasn't microdosing her glp. She was on a max dose that kept increasing, increasing, increasing. Yes, of course she was experiencing the side effects, but it wasn't working. It was doing nothing. It wasn't helping her lose weight, it wasn't helping lure her a 1C. And I will tell you, we have seen a boatload of this come into the practice. So many of you are on a GLP1 and it's not working. You're wasting your money. Now you can add in that GLP1. You can add it in at a microdose, you can add it in at a moderate standard dose. If you do need some help in that metabolism department because your A1C is a little bit high, your insulin is high. If we are using it to literally help get you into a metabolically beneficial state, out of that metabolically broken metabolic chaos state, into an efficient fat burner, then yes, we can use that higher standard dose, not too high to where you're getting all the side effects. We can use that moderate standard dose to get your body to lower that inflammatory A1C. Because when our A1C is elevated, we are in a state of inflammation, full body inflammation. We are set up for an increased risk of Alzheimer's, dementia, cancer, heart disease, all day long. We want to get you out of that state, but we use it for the amount of time that it takes to get get you out of that state. Then we move to micro doing and that's where you are getting that anti inflammatory benefit, the liver protection, the brain protection, as well as that little bit of support to maintain your weight loss and to keep your A1C and your insulin where we want it. All of that cannot be accomplished unless you optimize your thyroid and your hormones. So consider this very brief podcast a public service announcement. I felt I needed to do this because I'm seeing so many of you in the just fix your thyroid Facebook group on Instagram. So many of you have this question of wait, I kept hearing about GLP1s and, and I joined this row program or this online program or whatever and I got my glps and I've been using it for three months, for six months, for a year and nothing is working. Why? Well, you have to look at your thyroid and your hormones and if one of those, or both of those are off balance, are low functioning or in the toilet. If your reverse T3 is high, your free T3 is low. If you have no hormonal function, you need to address that first. Set the GLP one aside, go quit wasting your money and bring it back in once you start that optimization process. Now, when we are working one on one with someone, we will micro dose a glp. But it's at the same time, it's at the same time that we are optimizing their thyroid. We're getting that T3 in, we're lowering the reverse T3, we're giving them the beautiful hormones that their bodies starved for and we just start very slow. We get that GLP one in at a micro dose and it's all, it's working with the thyroid, it's working, working with the hormones, Everything is working beautifully together. The patient is being educated on Their diet, on their lifestyle. We're addressing nutrient deficiencies. We're doing all those beautiful things together. And then that microdose starts to work. Then you get your bang for your buck. Then everything comes together in a beautiful symphony and you lose the weight and you become metabolically healthy. You don't lose your sexy, lean muscle. Oh. Because we're increasing your testosterone over here, which is going to protect your muscle. Oh. And that's right, we talked to you about your protein intake, which you weren't getting enough of. So that's going to protect your muscle. You protect that beautiful, sexy, lean muscle, and you lose the body fat and you feel amazing and you reduce your risk of Alzheimer's, cancer, cardiovascular disease, inflammation. You help your joints, you help your gut. Everything is happy and singing praises to you from your body as opposed to you just throwing a GLP on it, crossing your fingers, wishing on a rainbow that it works because all the influencers are talking about it. And you're seeing women on IG showing their bellies left and right saying, just buy my IG of one or my GLP program and you'll be fine. No, that's not the case. Shame on them. They should be standing there saying, yes, you can have abs like mine and you can lose all the weight only if you optimize your thyroid and your hormones first. And then this GLP one that I'm selling over here will actually work. Will actually work. So if you are on the struggle bus and you're using a GLP and this is hitting home for you, you're going, you know what? Yeah, I've lost about a thousand dollars over the last few months. It's not doing garbage, not doing squat. Then I beg you, I implore you, please, please, please, get your thyroid thoroughly tested, get all your hormones done, work with someone that knows what they're doing with your thyroid and your hormones, get those optimized and quit wasting your money. I love me some GLPs when they're used in the right way and when they're not being pushed on you by somebody who's just trying to make a buck, who isn't telling you these important things. And I'm telling you right now, you need to get your thyroid hormones optimized for that drug to work. The information shared on the Thyroid Fixer podcast is intended solely for informational and educational purposes. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with your physician or other qualified healthcare provider with any questions you may have regarding a medical condition, treatment or before making changes to your healthcare regimen, including medications, supplements or other therapies. Use of the information provided in this podcast does not establish a doctor, patient or client provider relationship between you and the host or between you and any other healthcare professionals featured on the show. Any medical opinions or statements made by guests are their own and do not necessarily reflect those of the host or affiliated parties. Statements regarding dietary supplements or health related products mentioned in this podcast have not been evaluated by the fda. These products are not intended to diagnose, treat, cure or prevent any disease. Some episodes of the Thyroid Fixer podcast may include sponsorships or affiliate links. The host may receive compensation for discussing or promoting promoting certain products or services. Any such sponsorships or affiliations will be clearly disclosed during the episode. All opinions expressed are those of the hosts or guests and do not necessarily reflect the views of any sponsors. The inclusion of a product or service does not imply endorsement by any healthcare professional featured on this podcast.
GLPs Are a Waste of Money...If You're Not Doing This
Host: Dr. Amie Hornaman
Release Date: November 18, 2025
In this episode, Dr. Amie Hornaman tackles the growing popularity of GLP-1 medications (like Ozempic and Mounjaro) for weight loss and metabolic health. She argues that while GLPs can be powerful, they are largely ineffective—and a waste of money—if foundational thyroid and hormonal imbalances are not first addressed. Dr. Amie makes the case for comprehensive, personalized care and shares a transformative patient case to illustrate her approach.
GLP-1s (like tirzepatide, Ozempic, Mounjaro) have clear medical benefits—when used properly.
“If you high dose these GLPs, if you’re not dosing them properly, you will get side effects. And you’re also more susceptible...massive constipation, nausea, extreme fatigue, hair loss.” (12:50)
Barbara was a type 2 diabetic, 150 lbs overweight, with an A1C over 11, and not improving despite a year on Ozempic.
“If you are on T4 only and you’re tossing in a GLP, just take your money to Vegas and give it to the dealers, put it in the slot machine. Nothing’s going to come back.” (20:40)
The thyroid controls glucose, insulin, A1C, and even sex hormone regulation.
“All your sex hormones also play a role in your body composition and in your insulin and glucose regulation...the thyroid will basically dictate whether or not your A1C will be high.” (26:20)
GLPs can accelerate progress—but only as part of a broader, holistic protocol.
“Everything is working beautifully together. Patient is being educated on their diet, on their lifestyle, we’re addressing nutrient deficiencies...then that microdose starts to work. Then you get your bang for your buck.” (41:00)
“You will be wasting your money if you are using GLPs for weight loss or you’re using it at a higher dose if your thyroid and your hormones are not getting optimized.”
– Dr. Amie, (01:03)
“If you are on T4 only and you’re tossing in a GLP, just take your money to Vegas and give it to the dealers, put it in the slot machine. Nothing’s going to come back...You might as well set it on fire.”
– Dr. Amie, (20:40)
“Your thyroid is the master gland. It controls your glucose, it controls your insulin, your A1C, your sex hormones...You cannot just see someone for your thyroid and have them ignore your hormones or half-ass your hormones.”
– Dr. Amie, (30:30)
“Everything is happy and singing praises to you from your body as opposed to you just throwing a GLP on it, crossing your fingers, wishing on a rainbow that it works because all the influencers are talking about it.”
– Dr. Amie, (44:15)
“If you are on the struggle bus and you’re using a GLP and this is hitting home for you...please, please, please, get your thyroid thoroughly tested, get all your hormones done, work with someone that knows what they’re doing...and quit wasting your money.”
– Dr. Amie, (49:00)
For listeners frustrated by lack of progress with GLPs or ongoing hypothyroid symptoms, Dr. Amie’s core advice remains: Start with the root causes—test, personalize, optimize your thyroid and hormones first. Then, and only then, will medications like GLP-1s deliver real, lasting results.