World Series game six, Trump on Canada talks, Ozempic for addiction, and more

Summary

Your World Tonight (CBC) – October 31, 2025

World Series Game Six, Trump on Canada Talks, Ozempic for Addiction, and More

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Episode Overview

On this special Halloween edition, hosts Dave Seglins and team capture the electricity around the Toronto Blue Jays' shot at World Series history, examine renewed friction and fleeting opportunities in Canada-U.S. trade relations, break news on a China-Canada diplomatic thaw, and dive into the science (and hype) around Ozempic’s potential in combatting addiction. The episode is rounded out with cautious advice on IV wellness therapies and a look at how Canadians are juggling baseball and trick-or-treating in a memorable cultural clash.

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Key Segments and Discussion Points

1. Toronto Blue Jays on the Brink of World Series Glory

(Segment starts: 00:58; In-depth at 02:24, 05:40, 08:46)

• Setting the Scene:
  Canadians are galvanized as the Jays lead the World Series 3-2 against the LA Dodgers, with Game 6 in Toronto on Halloween night, a moment of national excitement unseen in decades.

• Fan Enthusiasm Nationwide:
  Fans describe traveling cross-country to Toronto, anticipation at Rogers Centre is “off the charts” (Jamie Strachan, 02:24).
  Notable quote (03:14, various fans):

  • “I'm going to scream my guts out. I am going to lose my voice when we win, it’s going to be epic... three years waiting. So go Blue Jays.”

• Game 6 Storylines:

  • Pitching rematch: Dodgers’ Yoshinobu Yamamoto (dominant in postseason) vs. Jays ace Kevin Gausman.
  • George Springer, key player struggling with injury, is back in the lineup.
  • Home field advantage: The Rogers Centre is “one of the most difficult places in baseball to play.” (Jamie Strachan, 05:18).

• Historic Weight:

  • Reference to previous Jays championships in 1992 and 1993—echoes of potentially repeating history.
  • Outfielder Rob Butler, winner with ’93 Jays, highlights Vladimir Guerrero Jr.’s standout impact:
    “He is unbelievable, breaking records, playing the game like he's playing in his school year.” (Rob Butler via reporter, 07:43)

• Jays Fever in Remote Canada:

  • Bars in Iqaluit packed, Halloween canceled in parts of the Arctic for the game.
  • Memorable moment (06:06):
    • “We actually canceled Halloween and said, we're going all in for baseball.”

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2. Canada-U.S. Trade Tensions & Trump’s “Tariff Tantrum”

(Segment starts: 09:40)

• Tariffs Imposed:

  • 25% U.S. tariff will hit Canadian medium and heavy-duty trucks; trade stalemate remains as President Trump refuses to re-engage after an Ontario-funded anti-tariff ad aired in the U.S.

• Trump’s Grievances:
  Notable quote (10:05, Trump speaking to reporters):

  • “You know what they did was wrong... He [PM Carney] apologized for what they did with the commercial because it was a false commercial... Ronald Reagan loved tariffs.”

• Ontario’s Response:

  • Premier Doug Ford stands by the ad, warning tariffs jeopardize the crucial Canada-U.S. partnership (Tom Perry, 11:14).

• White House Says Canadians “Rude and Dismissive”:

  • Trump’s Economic Council director Kevin Hassett:
    “He’s tried to negotiate with the Canadians... and they've been frankly rude and dismissive.” (11:29)

• Canada Still Hopes for Dialogue:

  • Prime Minister Mark Carney signals Canada’s readiness to return to talks “whenever the U.S. is ready.” (Tom Perry, 12:15)

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3. Diplomatic Thaw: Canada and China Reconnect

(Segment starts: 12:38, Interview at 13:05)

• Historic Meeting:

  • PM Mark Carney and President Xi Jinping hold first Canada-China leader talks since 2017 at APEC summit in South Korea.

• Aiming for Reset:

  • Carney views this as a “door opener” for dialogue—no breakthroughs yet, but signal of normalization.

• Economic Stakes:

  • Trade disputes persist (canola, EV tariffs), and both sides commit to resolving “irritants.”
  • Ongoing issues: Tourism, foreign interference, diaspora concerns.

• Expert Perspectives:

  • Jeff Nankibel (Asia Pacific Foundation): U.S.-Canada friction creates “timing” for this reset—previously politically difficult.
  • Goldie Heider (Business Council of Canada):
    “We're never going to be the best of friends. We are going to compete, but... we're going to look out for ourselves as well.” (15:21)

• Next Steps:

  • Carney invited for a state visit and further talks in China (15:33).

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4. Gaza Ceasefire Challenges and Devastation

(Segment starts: 15:43)

• On the Ground in Gaza:

  • CBC’s Kristo Gamansing reports from a rare press embed with Israeli forces, touring monumental destruction in Sejaya, Gaza City.
  • UN: Over 80% of Gaza structures damaged/destroyed (“hell on earth”).

• War’s Toll Amid Fragile Truce:

  • Despite truce, IDF reprisal strikes continue after Israeli soldier’s death.
  • Individual stories of loss and survival—searching for loved ones in rubble.

• IDF’s Stance:

  • Lt. Col. Navda Shoshani:
    “Before we can speak about the rehabilitation... Hamas needs to return all the hostages.” (18:09)

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5. Ozempic and the Science of Anti-Desire Drugs

(Segment starts: 19:36; First mention 09:05, in-depth at 20:24)

• Unexpected Effects:

  • GLP-1 drugs (like Ozempic) not only suppress appetite for food but appear to blunt interest in alcohol, cigarettes, opioids.

• Real Stories:

  • Mike McCluskey (Nova Scotia):
    “I was known as a heavy drinker. On Ozempic... No, there's no desire. That's just it. It just doesn't even enter my mind.” (20:45)

• Science Cautions:

  • Mechanism: May blunt pleasure-inducing dopamine surges (James McKillip, McMaster).
  • Early studies show reductions in heavy drinking days; researchers call for much larger, longer-term studies (Christian Hendershot, 21:47).

• Potential and Limits:

  • Providers urge evidence before touting as addiction treatment (Dr. Sanjeev Sokalingam, Centre for Addiction and Mental Health):
    “I think we have some good signals and we definitely need greater treatments… but I really would encourage us to make sure that we have the evidence base for this.” (22:18)

• Downside Risks:

  • Drugs might dull all desire—including for healthy pursuits (21:29).
  • Addiction recovery relies on finding pleasure in non-destructive activities (22:43).

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6. IV Wellness Clinics: Booming Industry, Big Gaps

(Segment starts: 22:59)

• Popularity vs. Oversight:

  • Clinics proliferating, promising energy, hangover cures, and hormone balance—often with minimal regulation.

• Health Risks:

  • Cross-contamination, infections, adverse reactions if not properly managed (Dr. Joseph Ross, Yale School of Medicine, 23:34).

• Regulatory Patchwork:

  • Stricter oversight in some provinces (Ontario College of Naturopaths); others lag, leaving gaps for risky practices.

• Skepticism on Benefits:

  • Leading health experts warn most claims are unproven; “red flag” for consumers (Timothy Caulfield, 25:20).

• Medical Advice:

  • Doctors recommend: Don’t use unless medically necessary and prescribed (Sarah Marshall, 25:39).

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7. Blue Jays vs. Halloween: The Great Canadian Dilemma

(Fun wrap, 25:50 onward)

• Cultural Collision:

  • Game 6 coincides with peak trick-or-treating hours, dividing families—do you watch baseball or go out for candy?

• Social Media Humor:

  • PSAs: “The candy’s on the porch, we’re all watching baseball.” (25:51)
  • Parents and kids conflicted:
    “My son is definitely conflicted because he wants a bag of candy, but he also wants to watch the baseball game.” (26:56)

• Memorable Quote (27:27, various fans):

  • “We don’t want to be here. We didn’t ask for this.”—on parents missing the game for trick-or-treating.

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Notable Quotes & Moments With Timestamps

• “People have been lining up since about noon... it’s not just people from Toronto, you’re talking to people from all across the country... It’s really the perfect setting tonight in Toronto.” — Jamie Strachan (02:24)
• “I think it’s an unbelievable likelihood because the Blue Jays have Vladimir Guerrero. He is unbelievable, breaking records...” — Rob Butler (07:43)
• “You know what they did was wrong... He [Carney] apologized for what they did with the commercial because it was a false commercial.” — President Trump (10:05)
• “We now have a turning point in the relationship that creates opportunities for Canadian families...” — Jamie Strachan, summarizing PM Carney (13:30)
• “Hamas has brought devastation on Israel and on Gaza.” — IDF Spokesperson, Lt. Col. Navda Shoshani (17:21)
• “No, there’s no desire. That’s just it. It just doesn’t even enter my mind.” — Mike McCluskey, on Ozempic (20:45)
• “In a lot of ways, these drugs are still unproven, and the hype is outpacing the evidence.” — James McKillip, researcher (21:11)
• “In fact, I think that these products should be viewed as a major red flag.” — Timothy Caulfield, on IV wellness clinics (25:34)
• “My son is definitely conflicted because he wants a bag of candy, but he also wants to watch the baseball game.” — Parent (26:56)
• "We don't want to be here. We didn't ask for this." — Canadian parents trick-or-treating instead of watching Blue Jays (27:27)

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Segment Timestamps

• Opening & Blue Jays National Mood: 00:58 – 08:46
• U.S.-Canada Trade & Trump Reactions: 09:40 – 12:38
• Canada-China Diplomatic Reset: 12:38 – 15:43
• Gaza War, Truce Update: 15:43 – 19:36
• Ozempic for Addiction Research: 19:36 – 22:59
• IV Clinic Risks & Trends: 22:59 – 25:50
• Blue Jays vs. Halloween Dilemma: 25:50 – End

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Episode Tone and Takeaways

“Your World Tonight” mixes spirited Canadian pride, analytical reporting, and candid, sometimes humorous dispatches from across the country and globe. The mood follows the day’s pulse—from euphoric sports anticipation to sobering policy realities and forward-looking medical debates—painting a multifaceted, deeply relevant portrait for listeners who want both context and character in their news.

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Transcript

[Sarah Marshall]

Hey, I'm Sarah Marshall and there's one story from the past that I've been circling around for years now. This eight part series traces the hidden history of the Satanic panic in North America. We'll connect the dots. From Victoria, B.C.

[Blue Jays Fan / Various Fans]

To the back roads of Kentucky, Satan was having a moment.

[Narrator / Reporter]

The sensationalist heartthrob of our time, the devil you know.

[Sarah Marshall]

Available now wherever you get your podcasts.

[Blue Jays Fan / Various Fans]

This is a CBC podcast. Couldn't take any chances. I was here bright and early. Started in Victoria. I drove to the ferry, Uber to the airport. I'm cold, but I'm excited because I know they're going to win the World Series. I made a vow to my wife, but I love the Blue Jays.

[Dave Seglins]

Let's go, Blue Jays.

[Jamie Strachan]

Bring it home, baby. Bring you home.

[Murray Brewster]

Baby.

[Narrator / Reporter]

Let's go.

[Dave Seglins]

It may not be a must win for the Blue Jays, but it is a must watch for millions of Canadians. Whether they're trekking to Toronto from across the country or cheering on from home, Canada is on the baseball bandwagon and tonight the World Series is on the line. Welcome to your World Tonight. I'm Dave seglins. It's Friday, October 31st, just before 6pm Eastern. Also on the podcast, you know what.

[Blue Jays Fan / Various Fans]

They did was wrong. He was very nice. He apologized for what they did with the commercial because it was a false commercial. You know, it was the exact opp.

[Dave Seglins]

President Donald Trump still mad about an anti tariff ad and still not ready to talk trade. But as Canada gets the cold shoulder from one trading partner, relations with another could be warming up.

[Jamie Strachan]

We now have a turning point in the relationship that creates opportunities for Canadian.

[Dave Seglins]

Families, China, Canada and new dialogue. After years of troubled diplomacy, even hardcore fans doubted they'd make it this far. But despite finishing last year in last place and a bad start to this season, the Toronto Blue Jays are one win away from the history books. Up three games to two on the LA Dodgers in the World Series. Our Jamie Strachan is outside the Rogers Center. Jamie, paint us a picture. What's going on there right now?

[Jamie Strachan]

Dave. We often hear the term electric when used to describe a crowd. But the crowd outside of Rogers center right now, really off the charts. People have been lining up since about noon, Eastern gates not opening until about three hours before the game. And when you walk up and down the line, Dave, it's not just people from Toronto. You're talking to people from all across the country, people who have traveled from far away to be at one of those games that you want to say, I Was there. It's really the perfect setting tonight in Toronto. Game six, the Blue Jays. A chance to win the World Series on a Friday night. It's Halloween. The pulse of downtown Toronto right now. Nothing like I can remember seeing in my lifetime, certainly as a reporter here in Toronto. Went up and down the line talking to some fans before waiting to get inside. Here's what they told me.

[Blue Jays Fan / Various Fans]

Oh, I'm going to scream my guts out. I am going to lose my voice when we win, it's going to be epic. We'll be on the streets singing Backstreet Boys until all hours of the night. It's amazing. We've been to so many games. World Series here once in life's opportunity. Hopefully not once in a lifetime, but three years waiting. So go Blue Jays.

[Narrator / Reporter]

It's just historic.

[Blue Jays Fan / Various Fans]

I don't know when in my lifetime, the next time I'm gonna see this.

[Jennifer Yoon]

So I just thought I have to.

[Jamie Strachan]

Dave, you heard that last fan talk about this could be a historic moment. Obviously, this Franchise has won two World Series, 1992 and 1993. It was 1993 that they were able to do it here in Toronto, hoping obviously to repeat that tonight here in Game six.

[Dave Seglins]

Let's move to on the field. What are some storylines we should be following tonight for the Jays and Dodgers?

[Jamie Strachan]

I think first and foremost, we've got to look at the pitching matchup. It's a rematch of what we saw in Game two. On the mound for the Los Angeles Dodgers, Yoshinobu Yamamoto. To be perfectly frank, this guy has been near impossible to hit in the postseason. Batters have struggled even to put the ball in play. He shut down the Jays in Game two. But no slouch on the mound for the Jays ace Kevin Gosman, who's been the heart and soul of this pitching staff all year. He's been great in the postseason as well. He's going to get the ball for the Blue Jays. The biggest question, Dave, around the lineup tonight, would George Springer play? George Springer really has been the most valuable player of this team all year. The heart and soul of that clubhouse. He looked like he hurt his back earlier in this series, and there was a question whether he was going to get back in. For Blue Jay fans, good news. He is in the lineup tonight. Here's manager John Schneider.

[Blue Jays Fan / Various Fans]

He was pretty close in game five.

[Dave Seglins]

I think having the extra day and a half helped. I think kind of just the feedback we got from him in the last couple of days helped and watched him swing.

[Blue Jays Fan / Various Fans]

So maybe a different story if you know this season has the potential to.

[Dave Seglins]

Just be two games if it had the potential to be another two weeks.

[Blue Jays Fan / Various Fans]

Maybe a little bit different.

[Dave Seglins]

But he's ready to go.

[Jamie Strachan]

So, Dave, there you have it. Blue Jays have two chances to win the World Series in a win tonight and it's over. They don't. We go to Game 7 tomorrow. The good news is they have been one of the best home teams in baseball. The Rogers center here in Toronto with the raucous crowd, one of the most difficult places in baseball to play.

[Dave Seglins]

All right, thanks, Jamie.

[Jamie Strachan]

Thanks, Dave. I appreciate it.

[Dave Seglins]

CBC reporter Jamie Strashen. It's not just fans in Toronto glued to seats and screens tonight. Across the country, Blue Jays stars like Vladdy, George and Trey are now household names and a remarkable post season ride. Well, that has the Jays nationwide bandwagon ready to pop. She and Desjardin has that part of the story.

[Narrator / Reporter]

The Jays craze has reached the arctic.

[Blue Jays Fan / Various Fans]

We are all baseball. We actually canceled Halloween and we said.

[Sarah Marshall]

We'Re going all in for baseball.

[Blue Jays Fan / Various Fans]

And that's been actually the hashtag of the Blue Jays. We want it all. So do we.

[Narrator / Reporter]

The Storehouse Bar and Grill in Iqaluit is quiet ahead of Game 6, but manager Valerie Hill doesn't expect that'll last long. It's become a hub for Jays fans here in Canada's northernmost city with hundreds showing up to watch the games.

[Blue Jays Fan / Various Fans]

It's insane that amount of people would.

[Sarah Marshall]

Come here just to cheer on the.

[Blue Jays Fan / Various Fans]

Jays with this positive energy that we have and it's absolutely incredible to be a part of.

[Narrator / Reporter]

Jay's merch dangles from the antler chandeliers. A neon blue concoction called the Vladi Bomb served on Jay's trays and on the food menu.

[Blue Jays Fan / Various Fans]

We had an Italian grand slam wich in honor of Vladdy's first grand slam.

[Narrator / Reporter]

It was the first in franchise postseason history and a defining moment for this Toronto Blue Jays team, now just one win away from becoming World Series champions.

[Blue Jays Fan / Various Fans]

And the Blue Jay fans making a ton of noise.

[Narrator / Reporter]

Jay's announced Dan Schulman knows nothing is ever set in stone. But the record shows both times they.

[Blue Jays Fan / Various Fans]

Have won the World Series, they've done it in six.

[Dave Seglins]

They've got a lot of good history in game sixes in their career.

[Blue Jays Fan / Various Fans]

I'm sure everybody would love them to.

[Narrator / Reporter]

Do it tonight, including Rob Butler. The outfielder won with the Jays in 93.

[Blue Jays Fan / Various Fans]

The winners and still world champions, the.

[Narrator / Reporter]

Toronto Blue Jays and is still the only Canadian to ever win the World Series with the Canadian team. A title he hopes to win soon. Share with Montreal born Vladimir Guerrero Jr.

[Blue Jays Fan / Various Fans]

I think it's an unbelievable likelihood because the Blue Jays have Vladimir Guerrero. He is unbelievable, breaking records, playing the game like he's playing in his school year. Like he knocked on the door and said, hey, let's go play some baseball against the Dodgers.

[Narrator / Reporter]

A team on the cusp of so much history and a country is on the edge of its seat. From Prince Edward Islanders scooping up last minute merch.

[Dave Seglins]

I might have a new hat, but.

[Blue Jays Fan / Various Fans]

I've been cheering for a long time. Take it home tonight. I think the Jays win it 6 4.

[Jamie Strachan]

I'm feeling very, very optimistic that the Jays are going to bring it back to Canada.

[Blue Jays Fan / Various Fans]

They've done a great job so far. And go Jays.

[Narrator / Reporter]

Go to Albertans flying in just for.

[Blue Jays Fan / Various Fans]

The game last second when the Jays won, I was like, dad, call them. You want to go to Toronto? Like literally last minute. This whole country is going to go crazy. They're our team too.

[Narrator / Reporter]

After a season of bubbling excitement, everyone stands more than ready to erupt. Celebrate one last win together and a very happy Blue Jays edition of Halloween Xi and Daejiada, CBC News, Toronto.

[Dave Seglins]

Coming right up, it's the ad that continues to divide Canada and U.S. trade officials still aren't talking after an anti tariff TV commercial. And the prime minister and China's president meet for the first time in years, hoping to strengthen ties and smooth over a diplomatic rough patch. And later we'll have this story.

[Jennifer Yoon]

Alcohol, nicotine and opioids. Early evidence suggests drugs like Ozempic might curb the appetite for more than just food. But scientists don't know why.

[Blue Jays Fan / Various Fans]

There's a lot we don't know. In a lot of ways, these drugs are still unproven and the hype is outpacing the evidence.

[Jennifer Yoon]

I'm health reporter Jennifer Yoon with the scientists trying to figure out if Ozempic is an anti desire drug and what what that could mean for treating addiction. That story later on youn world tonight.

[Dave Seglins]

U.S. tariffs on Canadian medium and heavy duty trucks will come into effect tomorrow. 25% applied to a range of pickup, cargo and transport trucks. Despite Canadian efforts, there has been no reprieve in Donald Trump's trade war. Trade talks between the two countries are still on hold and the US President says he is still bothered by an anti tariff ad from the Ontario government. Tom Perry has the details.

[Blue Jays Fan / Various Fans]

Mr. President. Speaking to reporters aboard Air Force One, US President Donald Trump bragged and boasted about the many successes he claims he made on his trip to Asia this week. The media with China was incredible. The media was Japan incredible. And the meeting with South Korea, likewise, incredible.

[Murray Brewster]

All of them.

[Blue Jays Fan / Various Fans]

Prime Minister Mark Carney was also in Asia meeting some of those same leaders. He and Trump crossed paths only briefly when they were seated across from one another at the Asia Pacific Economic Cooperation summit in South Korea. But Trump says he's not ready to resume trade talks with Canada, even though he and Carney still get along. No, but I have a very good relationship. I like him a lot. But you know, what they did was wrong. He was very nice. He apologized for what they did with the commercial because it was a false commercial. You know, it was the exact opposite. Ronald Reagan loved tariffs. The commercial that Trump claims infuriated him so much he terminated trade talks and threatened a new 10% tariff on Canada was bought and paid for by the government of Ontario to air in the US when someone says let's impose tariffs.

[Dave Seglins]

On foreign imports, it looks like they're.

[Blue Jays Fan / Various Fans]

Doing the patriotic thing by protecting American products and jobs. The ad used a 1987 radio address by former U.S. u.S. President Ronald Reagan to criticize tariffs, one of Trump's favorite political and economic tools. Trump called the ad fake and has repeatedly insisted Reagan, one of the architects of the original Canada U.S. free Trade Agreement, was actually a big fan of tariffs. Ontario Premier Doug Ford has defended the ad and today warned in an opinion piece published in the Washington Post that tariffs were testing Canada's long standing partnership with the U.S. as for the Prime Minister's office office, it's not said whether Carney has apologized for the ad, as Trump claims. But Kevin Hassett, Trump's National Economic Council director, says the ad isn't the only sore point for his boss, the US President. He's tried to negotiate with the Canadians to get better deals for Americans and they've been frankly rude and dismissive. And this is how it gets to where we are. Mark Carney has maintained from the get go Canada and the U.S. were making progress on trade and that Canada is prepared to go back to the negotiating table whenever the US Is ready, though Trump, for whatever reason, is not there yet. Tom Perry, CBC News, Ottawa.

[Dave Seglins]

As the U.S. president continues to push Canada away, officials in this country are trying to bring another economic superpower closer. Prime Minister Mark Carney held a bilateral meeting with the President of China. It happened on the sidelines of the APEC summit in South Korea and and it marks the first formal leader to leader contact between the two countries since 2017. Murray Brewster is traveling with the Prime Minister.

[Murray Brewster]

Chinese President Xi Jinping acknowledging the rift between his country and Canada, saying Beijing wants to push the relationship back onto a healthy, sustainable path. He and Prime Minister Mark Carney met for almost 40 minutes.

[Jamie Strachan]

This meeting today is long overdue.

[Murray Brewster]

Going into this high stakes meeting, Carney tried to temper expectations, suggesting it was a door opener, a resetting of relations with China.

[Jamie Strachan]

We now have a turning point in the relationship, a turning point that creates opportunities for Canadian families, for Canadian businesses and Canadian workers, and also creates a path to address current issues.

[Murray Brewster]

But precisely what that path looks like is unclear. Chinese tariffs on Canadian canola and Canadian levies on Chinese electric vehicles remain in place. The prime minister's office says both leaders told officials to move quickly to resolve outstanding trade issues and irritants. They're also going to look for solutions to quote sensitivities, and there are plenty of those, from tourism restrictions to Chinese bullying of diaspora communities. During the leaders debate in last spring's federal election, Carney described China as the biggest foreign interference threat the country was facing.

[Blue Jays Fan / Various Fans]

Well, I think part of it is a matter of timing.

[Murray Brewster]

Jeff Nankibel is with the Asia Pacific foundation of Canada, and he says Canada's deteriorating relationship with the United States has set the conditions for Canada and China to get past the bad blood that's.

[Blue Jays Fan / Various Fans]

Been created after the affair of Meng Wanzhou. The two Michaels I don't know. You know, I don't think there's a prime minister out there who would have been in a position to have some kind of a reset of the relationship immediately. So I think it's partially a question of timing and we also have circumstance.

[Murray Brewster]

Carney's dialogue with Xi comes one day after the Chinese leader sat down with US President Donald Trump, a meeting that dialed back the trade war between the two economic superpowers. For the time being. Goldie Heider of the Business Council of Canada says the U.S. had a clear message to China this week.

[Blue Jays Fan / Various Fans]

We're never going to be the best of friends. We are going to compete, but we're going to have to figure out how to do it. And if America is sending that signal, then it's clearly an opportunity for Canada to say, well, we agree and we're going to do the same thing. We're going to look out for ourselves as well.

[Murray Brewster]

Carney has been invited to China for a state visit and further talks, and he says he'll go. Murray Brewster, CBC News, Gyeongju, South Korea.

[Dave Seglins]

Turkey's foreign minister says his country will host a meeting of Muslim nations next week. The focus will be the Gaza ceasefire, the first stage of the truce between Hamas and Israel has already faced serious challenges and people in Gaza are still struggling to access food, clean water and medicine. The CBC's Kristo Gmansing recently joined an Israeli Defense Force press trip into one part of the enclave and she brings us this report.

[Kristo Gamansing]

With the tires of the IDF jeep churning up the dust on the path entering the outskirts of Gaza City, the first signs of destruction come into view. Sejaya and the area around it was one of the hardest hit locations in Gaza. Now a military base stands behind an invisible yellow line signifying Israeli control. Looking out onto what was once one of the biggest, busiest neighborhoods in Gaza, an unencumbered view of utter devastation. Senior Israeli military officials say they wanted to take us to this location to show us what they said were, quote, the consequences of a terrorist organization setting up and waging a war. From in, around and below civilian areas, blocks and blocks of bombed out buildings, some still erect, others in what appear to be massive ashy mounds mixed with metal. The UN says more than 80% of all structures in the territory have either been destroyed or damaged in Israeli attacks over the course of the past two years, with multiple UN spokespeople describing it as hell on earth.

[Blue Jays Fan / Various Fans]

Hamas has brought devastation on Israel and on Gaza.

[Kristo Gamansing]

Lt. Col. Navda Shoshani is an IDF spokesperson, the only person we were permitted to speak with on the record. CBC accepted an invitation from the IDF to take a small group of journalists on a time limited and location specific embed on Tuesday. With independent access for media into Gaza banned By Israel Since October 7, this is the only way to see the destruction at a closer range for ourselves. As agreed. CBC submitted video captured during the embed. The IDF did not request any changes. What's Israel's role in cleaning this up? In making it not a horrific scene?

[Blue Jays Fan / Various Fans]

Before we can speak about the rehabilitation, which is an international effort that Israel is committed to, the first stage of the agreement needs to be held. The agreement says that within 72 hours, which passed two weeks ago, already Hamas needs to return all the hostages.

[Kristo Gamansing]

We didn't know it at the time when we entered Gaza, but an IDF soldier was killed in an attack behind the yellow line in Rafah. It led to Israel launching a series of reprisal strikes across the strip. Despite the ceasefire, more than 100 Palestinians were killed. According to the Hamas run Civil Defense Agency in nearby Jabalya, Bilal Ryhan is squeezed into a tiny opening in the rubble, a mallet and trowel in hand. The area is also a debris field, but beyond where we were permitted to be. Rehan speaks with a freelance video journalist working for cbc. He's scavenging the ruins for clothes, household items and maybe dead loved ones. Two of his cousins, he said, are somewhere under the rubble. The question for many across Gaza is where to start looking, given the swath of devastation. Crystal Gamansing, CBC News, Sejaya, Gaza.

[Dave Seglins]

Opposition leader Pierre Poiliev and the premiers of Ontario and Quebec say Ottawa should reject a Supreme Court decision on mandatory minimum sentences. The court ruled mandatory minimums for possession and access to child pornography are unconstitutional. Justice Mary Moreau said for some offenses, a one year sentence would be grossly disproportionate. Poliev says the federal government should invoke the notwithstanding clause to ignore the ruling. Popular GLP1 drugs like Ozempic are curbing people's appetites and not just for food, but also alcohol, cigarettes and opioids. And while that might sound like a great way to treat addiction, scientists caution there's still a lot we don't know about the medications. Jennifer Yoon brings us up to date on the latest research.

[Blue Jays Fan / Various Fans]

This is a can I've had now for four years on the shelf.

[Jennifer Yoon]

A can of beer left untouched for years. Mike McCluskey says that would have been unthinkable before Ozempic.

[Blue Jays Fan / Various Fans]

I was known as a heavy drinker on Ozempic.

[Jennifer Yoon]

The Dartmouth, Nova Scotia man lost 110 pounds unexpectedly. He also lost his appetite for alcohol.

[Blue Jays Fan / Various Fans]

No, there's no desire. That's just it. It just doesn't even enter my mind.

[Jennifer Yoon]

He's not alone. Combing through past patient data, researchers have found those who take drugs like Ozempic and Zepbound for type 2 diabetes and weight loss seem to want less and consume less of all kinds of things, not just food. That includes addictive substances like alcohol, nicotine, and even opioids. Scientists don't know exactly why.

[Blue Jays Fan / Various Fans]

In a lot of ways, these drugs are still unproven, and the hype is outpacing the evidence.

[Jennifer Yoon]

But they've got some idea, says James McKillip, an addictions researcher at McMaster University.

[Blue Jays Fan / Various Fans]

That's the working hypothesis that basically it's having a blunting effect on that spike in dopamine.

[Jennifer Yoon]

Dopamine is a neurotransmitter released in the brain. When you do something enjoyable, it also motivates you to repeat that action. In one of the few small clinical trials done so far, researchers put one group of heavy drinkers on semaglutide, the active ingredient for ozempic and compared them to a group given placebos.

[Blue Jays Fan / Various Fans]

It did reduce how much they were drinking.

[Jennifer Yoon]

Christian Hendershot is the co author of the study published in the peer reviewed journal JAMA Psychiatry. His study found people on semaglutide had fewer heavy drinking days than those who weren't.

[Blue Jays Fan / Various Fans]

So the next step is to really test these effects in larger samples, larger numbers of people, and it's important to extend these findings over longer treatment periods.

[Jennifer Yoon]

Still, those treating people with addiction, like Dr. Sanjeev Sokalingam at the Centre for Addiction and Mental Health in Toronto, are feeling cautious optimism.

[Jamie Strachan]

I think we have some good signals and we definitely need greater treatments available for addictions and addictions treatment. I really would encourage us to make sure that we have the evidence base for this.

[Jennifer Yoon]

As researchers look into the drug's potential for treating addiction, they're also worried about another possible side that the drugs could blunt all desire, even for healthy things.

[Blue Jays Fan / Various Fans]

Motivation for physical activity, motivation for socializing.

[Jennifer Yoon]

A key part of addiction's recovery, McKillop says, is a healthy lifestyle which depends on the pleasure people find in life like exercise, hobbies and the company of loved ones. Ones Jennifer Yoon, CBC News, Toronto.

[Dave Seglins]

Private clinics offering intravenous therapy have popped up all over Canada and they promise all kinds of health benefits, from boosting energy to beating a hangover, even balancing hormones. But some health experts warn the infusions come with significant risks and not enough regulations. Lauren Pelley explains.

[Blue Jays Fan / Various Fans]

My client booked in for a glutathione and vitamin, vitamin C IV drip.

[Sarah Marshall]

Social media is filled with ads for intravenous therapy, cocktails of vitamins and supplements that cost hundreds of dollars and get injected right into someone's veins.

[Blue Jays Fan / Various Fans]

The growth that you're seeing probably is in part because there is so little regulatory oversight.

[Sarah Marshall]

Dr. Joseph Ross is with the Yale School of Medicine. He's part of a research team that recently studied the booming business of IV therapy south of the border. They found less than a third of clinics required consultation with a licensed medical professional before treatment or described the potential health risks. Those include possible cross contamination, adverse reactions or even serious infections.

[Blue Jays Fan / Various Fans]

If consumers are going to go off and use these particularly often without their doctors even knowing that they're using these, we have to make sure the safeguards are in place that nobody gets hurt.

[Sarah Marshall]

CBC News found private IV clinics on this side of the border border often fall into a regulatory grey zone as well. Health Canada authorizes intravenous health products, while a patchwork of provincial watchdogs monitor workers such as naturopaths, physicians or registered nurses. In Ontario, the College of Naturopaths even operates an inspection program specifically for IV clinics. Given the level of risk, which arm.

[Jennifer Yoon]

Would you like to be poked?

[Sarah Marshall]

At a wellness center in Mississauga, Naturopath Yelena Deshaun Jschko says her team members adhere to strict safety standards for their IV offerings, including a sterile environment, patient exams and vital checks.

[Narrator / Reporter]

We are regulated by the college and we go through inspections with the college prior to providing this treatment to patients.

[Sarah Marshall]

But Deshko worries that's not the case everywhere. She says a recent customer told her she passed out during a session at a different facility after being given a partially frozen IV bag.

[Narrator / Reporter]

And this really concerns us as providers.

[Jennifer Yoon]

Of this treatment because it can be.

[Narrator / Reporter]

Very dangerous for the patient.

[Blue Jays Fan / Various Fans]

Unfortunately, I think these IV clinics, they're falling through the cracks.

[Sarah Marshall]

Timothy Caulfield is one of Canada's top experts on health and wellness trends. The University of Alberta professor says the biggest issue is there's often no evidence backing up claims about IV therapy's long list of possible health benefits.

[Blue Jays Fan / Various Fans]

In fact, I think that these products should be viewed as a major red flag.

[Sarah Marshall]

Doctors told us if you're sick, seek medical advice, and if you're healthy, there's typically no need for any type of IV therapy. Lauren Pelly, CBC News, Toronto.

[Dave Seglins]

And we'll end tonight with a bit more on the Toronto Blue Jays. Game 6 in Toronto and a chance to win the World Series. And just about on any other day, this would be the main event. But tonight there's competition. Social media is full of funny takes about tonight's matchup on the calendar, unofficial PSAs like this one advising kids the candy's on the porch. We're all watching baseball.

[Blue Jays Fan / Various Fans]

Trick or treat.

[Dave Seglins]

First pitch tonight around 8 o' clock Eastern. Now in Eastern and Atlantic time zones. That's not bad. Newfoundland, even better. Trick or treating should be winding down, but moving west, the Jays are up against prime trick or treating time, setting up tonight's great Canadian dilemma, a decision as difficult as a late inning call to the bullpen. Home runs or Halloween?

[Blue Jays Fan / Various Fans]

I think that's a very good question for any parent. I can tell you that my son is definitely conflicted because he wants a.

[Dave Seglins]

Bag of candy, but he also wants.

[Blue Jays Fan / Various Fans]

To watch the baseball game. I'll just, I was planning to go.

[Sarah Marshall]

To Halloween party, but that's just going.

[Blue Jays Fan / Various Fans]

To turn into a watch party. So go Blue Jays, go.

[Jamie Strachan]

It's Halloween all the way. No offense, I love the Blue Jays.

[Blue Jays Fan / Various Fans]

But you know, you can record the game, you can't record Halloween get home early. We want trick or treating to end.

[Sarah Marshall]

By 8 o'clock tonight.

[Dave Seglins]

And for those baseball fans who can't manage to get home early, another social media meme. Canadian parents trick or treating with their kids instead of watching the World Series.

[Blue Jays Fan / Various Fans]

We don't want to be here. We didn't ask for this.

[Dave Seglins]

As fierce as the Blue Jays have been playing, kids on Halloween are pretty much unbeatable. So wherever the night takes you, we hope you enjoy Halloween and the baseball game. Consider it a doubleheader. Thanks for being with us. This has Been youn World Tonight for Friday, October 31st. I'm Dave Seglins. Take care.

[Blue Jays Fan / Various Fans]

For more CBC podcasts, go to CBC CA podcasts.