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Welcome to This Week in Emergency Medicine. This week we're covering seven notable papers spanning post-cardiac-arrest critical care, risk stratification and decision rules in trauma, and equity and quality in acute pain and toxicology care. Let's dive in. We start with two large trials that both ask whether more intensive post-arrest intervention actually helps, and both answer no. In the New En…This week's papers:Conservative Oxygen for Unresponsive Patients after Cardiac Arrest — New England Journal of Medicine 2026Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest: The ICECAP Randomized Clinical Trial — JAMA 2026Risk stratification for significant acute traumatic intracranial hemorrhage in older adults after a ground-level fall: A prospective multicentre cohort study — PLOS Medicine 2026Early vs delayed opioid administration for pediatric sickle cell vaso-occlusive crisis: A systematic review and meta-analysis — American Journal of Emergency Medicine 2026Predicting Prehospital Blood Transfusion After Motor Vehicle Trauma — Prehospital Emergency Care 2026Disparities in the use of anxiolysis or sedation for facial laceration repair in the pediatric emergency department — American Journal of Emergency Medicine 2026Carbon monoxide-induced myocardial injury: Mechanisms, structural Remodeling, and clinical implications — American Journal of Emergency Medicine 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we're covering 10 notable papers spanning critical airway and resuscitation strategies, time-sensitive vascular emergencies, and age-specific risk stratification in the emergency department. Let's dive in. We begin with critical updates in airway management and mechanical ventilation, starting in the prehospital arena. A large observational st…This week's papers:Mechanical Versus Manual Cardiopulmonary Resuscitation Causing Traumatic Cardiothoracic and Abdominal Injuries: A Meta-Analysis and Systematic Review of Randomized Trials — The Journal of Emergency Medicine 2026Drip-and-Ship versus Mothership Model in Acute Ischemic Stroke: A Meta-Analysis Stratified by Stroke System Integration — The Journal of Emergency Medicine 2026Landmark Versus Ultrasound-Guided Identification of the Cricothyroid Membrane: A Randomized, Prospective Trial — The Journal of Emergency Medicine 2026High-Flow Nasal Cannula Therapy for Apneic Oxygenation during Rapid Sequence Induction in the Emergency Department: A Systematic Review — The Journal of Emergency Medicine 2026The Prevalence of Adverse Events After Prehospital Neuromuscular Blockade-Assisted Airway Management — Prehospital Emergency Care 2026Age as a Predictor of Mortality, Disability, or Need for Acute Resuscitative Care in Trauma Patients — Academic Emergency Medicine 2026Time-Critical Diagnosis of Pediatric Testicular Torsion in a Tertiary Pediatric Emergency Setting: Integrating Clinical Predictors With Selective Doppler Ultrasound — The Journal of Emergency Medicine 2026Evidence for Electrocardiographic Patterns Identifying Acute Coronary Occlusion in Non-ST-Elevation Acute Coronary Syndromes: A Scoping Review — Academic Emergency Medicine 2026Reducing Hyperoxemia in Mechanically Ventilated Emergency Department Patients: A Before-and-After Study — The Journal of Emergency Medicine 2026Signs of Life During Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study — Prehospital Emergency Care 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we are covering ten notable papers spanning prehospital resuscitation and critical care, pediatric emergency stewardship, and emerging procedural and metabolic updates in the emergency department. Let's dive in. Let's begin in the prehospital arena, where the choice of resuscitation fluid and advanced interventions in hemorrhagic shock remain…This week's papers:Efficacy and safety of prehospital whole blood resuscitation in traumatic haemorrhagic shock a systematic review and meta-analysis. — The American journal of emergency medicine 2026In children presenting to the paediatric emergency department (PED) with acute gastroenteritis, does the use of probiotics lead to a shorter duration of diarrhoeal symptoms? — Emergency medicine journal : EMJ 2026Point-of-care ultrasound-guided regional anaesthesia: pericapsular nerve group (PENG) block for patients with hip fracture. — Emergency medicine journal : EMJ 2026Just the facts: Novel management updates of diabetic ketoacidosis in the emergency department. — CJEM 2026Initial vascular access for neonatal resuscitation: a systematic review. — Resuscitation 2026Prehospital resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and cardiac arrest: a systematic review. — Prehospital emergency care 2026Dissociation between resuscitation success and neurological recovery in nursing home cardiac arrest: A propensity-matched analysis. — The American journal of emergency medicine 2026Determinants of Timely Prehospital Thrombolysis Administration within a Pharmacoinvasive STEMI Network in Victoria, Australia. — Prehospital emergency care 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we're covering 5 notable papers spanning emergency department ultrasound applications and clinical practice variations. Let's dive in. We begin with a focus on expanding clinical ultrasound applications in the emergency department, where new evidence highlights both diagnostic versatility and substantial system-wide benefits. In the American J…This week's papers:Early Intensive Blood Pressure Reduction After Intracerebral Hemorrhage Is Associated With Worse Functional Outcome: The Risk of Overshooting Blood Pressure Goals. — Annals of emergency medicine 2026Novel point-of-care ultrasound approaches for shoulder dislocation: Alternative windows, diagnostic signs, and a stepwise protocol. — The American journal of emergency medicine 2026Ultrasound-guided peripheral intravenous access in the emergency department: A national cost, complication, and throughput analysis. — The American journal of emergency medicine 2026Physician Sex and Practice Pattern Differences in the Emergency Department. — JAMA internal medicine 2026Practice Pattern and Outcome Differences in the Emergency Department by Physician Sex. — JAMA internal medicine 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we are covering six notable papers spanning critical care and resuscitation, diagnostic imaging pathways, and the safety of our daily emergency department procedures. Let's dive in. We begin with diagnostic pathways and the ongoing effort to balance clinical safety with the overuse of advanced imaging. For years, emergency clinicians have reli…This week's papers:YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer: A Randomized Clinical Trial. — JAMA 2026RhD-Positive Transfusion in Females of Childbearing Potential in Hemorrhagic Shock: Risk, Reality, and Policy. — Prehospital Emergency Care 2026Systematic review of diagnostic test accuracy of point-of-care gastric ultrasound by emergency physicians. — Internal and Emergency Medicine 2026Clinician characteristics associated with CT use in children with minor blunt head trauma at very low risk for clinically important traumatic brain injuries. — Emergency Medicine Journal 2026Discordant Neuron-Specific Enolase and Neurologic Outcomes in Out-of-Hospital Cardiac Arrest: A Decade-Long Analysis. — Resuscitation 2026Ultrasound-guided peripheral IV placement practices: A national survey of gel and probe cover use. — The American Journal of Emergency Medicine 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we are covering ten notable papers spanning advanced airway and ventilation management, post-arrest and pediatric sedation strategies, and diagnostic challenges in cardiovascular and reproductive emergencies. Let's dive in. We begin with critical airway management in the emergency department, where a prospective registry study published in the…This week's papers:Incidence and Outcomes of Emergency Physician-Performed Awake Intubations: A Report From the Airway Interventions Registry and Observational Database — Annals of emergency medicine 2026In intermediate-risk PE, adding US-CDT to anticoagulation reduced a composite adverse clinical outcome within 7 d — Annals of internal medicine 2026In acute hypoxemic respiratory failure, high-flow vs. standard oxygen therapy did not reduce mortality at 28 d — Annals of internal medicine 2026Just the facts: fomepizole for acetaminophen overdose — CJEM 2026Is there evidence that intranasal ketamine can provide adequate procedural sedation in paediatric patients? — Emergency medicine journal : EMJ 2026Volume-controlled mechanical ventilation during cardiopulmonary resuscitation: A systematic review and meta-analysis — Resuscitation 2026Sedation Early After Return of Spontaneous Circulation and During Pre-Hospital Transport After Out-Of-Hospital Cardiac Arrest: Retrospective Analysis of the AfterROSC1 & 2 Database — Resuscitation 2026Contemporary diagnostic accuracy evidence and adjunctive high-frequency linear transducers in first-trimester pregnancy POCUS — CJEM 2026Exploring the puzzle of positive troponin results in patients with renal disease — CJEM 2026The cost of waiting: diagnostic ultrasound delays in ectopic pregnancy — CJEM 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we are covering six notable papers spanning key strategies in out-of-hospital cardiac arrest resuscitation, prehospital medication administration, and neonatal resuscitation techniques. Let us dive in. We begin with a deep dive into how we support and evaluate bystander cardiopulmonary resuscitation, which remains a cornerstone of survival in…This week's papers:Telemedicine-Assisted vs Conventional Telephone Instruction in Cardiopulmonary Resuscitation: The TACTIC Cluster Randomized Trial — Resuscitation 2026Optimal Site of Tactile Stimulation during Initial Steps of Neonatal Resuscitation: A Three-Arm Randomized Controlled Trial — Resuscitation 2026Prehospital epinephrine as a bridge to survival in traumatic cardiac arrest: A nationwide propensity score-matched analysis — The American Journal of Emergency Medicine 2026Association of Rescue Breathing With Outcomes in Adult Suffocation-Related Cardiac Arrest — Resuscitation 2026Paramedic-assessed quality of bystander CPR is associated with survival in out-of-hospital cardiac arrest — Resuscitation 2026Sex Differences in OHCA Outcomes Are Driven by Arrest Circumstances Rather Than Different EMS Treatment: - a nationwide registry study from Norway 2015-2024 — Resuscitation 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we're covering 9 notable papers spanning diagnostic innovations, artificial intelligence in triage, and preventive care strategies. Let's dive in. We begin with diagnostic and risk-stratification advancements in the acute care setting, starting with a compelling study published in the Emergency Medicine Journal that examines the use of transoe…This week's papers:Cardiovascular outcomes and safety associated with statin therapy for primary prevention in older adults with type 2 diabetes: A target trial emulation study. — PLoS Medicine 2026Concordance between an artificial intelligence self-triage programme and physical triage. — Emergency Medicine Journal : EMJ 2026A case of artificial intelligence-enhanced diagnostics leading to heart transplantation. — Nature Medicine 2026The effect of oxygen administration on systemic oxidative stress in patients presenting in the emergency department: a prospective cohort study. — European Journal of Emergency Medicine 2026Trends in ketamine-related emergency department presentations across European centres: a Euro-DEN Plus Study (2013-2023). — European Journal of Emergency Medicine 2026National Trends in Patient Messaging-The Growing Electronic Inbox. — JAMA 2026A scoping review of emergency department take-home naloxone on patient and health outcomes. — CJEM 2026Real-time identification of aetiology in patients able to undergo transoesophageal echocardiography with non-traumatic out-of-hospital cardiac arrest in China: a prospective, single-centre exploratory study. — Emergency Medicine Journal : EMJ 2026Risk of obstructive acute kidney injury: derivation and internal validation of a risk stratification tree. — Emergency Medicine Journal : EMJ 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we're covering 10 notable papers spanning resuscitation controversies in sepsis and cardiac arrest, new data on optimizing systems of care for trauma and stroke, and the growing role of artificial intelligence in our daily workflow. Let's dive in. We begin this week in the resuscitation bay, with major papers challenging long-held practices in…This week's papers:Inclusion of Hospital Performance in Prehospital Stroke Routing: A Simulation Study. — Prehospital emergency care 2026Estimated Effectiveness of 2024-2025 COVID-19 Vaccines in Adults. — JAMA internal medicine 2026Computable Structured Phenotype Versus Large Language Model Identification of Opioid Use Disorder Using Electronic Health Record Data. — Annals of emergency medicine 2026Updated International Patient Decision Aid Standards (IPDAS version 5.0): modified Delphi, evidence informed consensus process. — BMJ (Clinical research ed.) 2026From permission to pride: a realist synthesis of how to improve emergency care for children in low-income and lower-middle-income countries. — The Lancet. Global health 2026Medical Scribe and Ambient Artificial Intelligence Impact on Emergency Physician Documentation Burden and Clinical Productivity. — Annals of emergency medicine 2026Pediatric Trauma Center Utilization for Children Transported by Emergency Medical Services. — Prehospital emergency care 2026Vasopressors or Fluids in Early Septic Shock. — The New England journal of medicine 2026Sodium Bicarbonate for In-Hospital Cardiac Arrest: A Randomized Clinical Trial. — JAMA 2026Listen at AudioScholar

Welcome to This Week in Emergency Medicine. This week we're covering 7 notable papers spanning critical care controversies, diagnostic dilemmas, and novel tools for the ED. Let's dive in. We begin in critical care, where a highly anticipated trial provides a definitive, and concerning, answer on a popular therapy for severe burns. Published in JAMA, the VICTORY randomized clinical trial investiga…This week's papers:High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial. — JAMA 2026Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study. — Resuscitation 2026Estimating the Effect of Hospital Admission on Health Care Outcomes and Spending Among Persons With Dementia : A Quasi-experimental Study. — Annals of internal medicine 2026Modified HEART score to improve ruling out acute coronary syndrome at the emergency department. — Internal and emergency medicine 2026Racial, gender and language based disparities in sepsis: a public health perspective. — Internal and emergency medicine 2026Guideline-Integrated Large Language Models Improve Decision Support for Acute Ear, Nose and Throat Emergencies. — The Journal of emergency medicine 2026Bicarbonate Administration in Severe Hyponatremia (BASH): A Retrospective Cohort Study of 8.4% Sodium Bicarbonate in Patients with Preserved and Reduced Renal Clearance. — The Journal of emergency medicine 2026Listen at AudioScholar