What role does prostate artery embolization (PAE) play in modern prostate cancer care? In this episode of BackTable Urology, Dr. Nainesh Parikh (Interventional Radiology at Moffitt Cancer Center) and Dr. Kosj Yamoah (Radiation Oncology at Moffitt Cancer Center) join Dr. Ruchika Talwar (Vanderbilt University) to discuss how PAE could become a key adjunct in optimizing radiation therapy outcomes.

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Timestamps

00:00 - Introduction
01:44 - Why Use PAE in Cancer
04:08 - Neoadjuvant and Salvage Use
07:26 - Radiation Planning Benefits
12:51 - PAE vs. Surgery
18:36 - SBRT Access
20:48 - Current Evidence and Trials
25:29 - Patient Selection
32:18 - PAE After Radiation
36:56 - When to Avoid PAE
40:29 - Long-Term Implications
44:28 - Conclusions

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More about this episode

They review how PAE can improve lower urinary tract symptoms and reduce prostate volume, potentially optimizing patients for radiation therapy, including stereotactic body radiotherapy (SBRT) and brachytherapy. The discussion highlights early clinical data and patient selection considerations such as gland size and symptom burden. Finally, they examine post-radiation applications, technical challenges, and current limitations, emphasizing the need for larger, multicenter trials to better define PAE’s role in prostate cancer treatment pathways.

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Resources

Prostate Artery Embolization in the Setting of Prostate Cancer: Review and Opinion
https://pmc.ncbi.nlm.nih.gov/articles/PMC11775958/

Ep. 297 How Prostate Artery Embolization Optimizes Radiation Outcomes with Dr. Nainesh Parikh and Dr. Kosj Yamoah