Are biomarkers the missing link in personalized prostate cancer care? What is the practical role of biomarkers across the prostate cancer treatment continuum? In this episode of BackTable Urology, Dr. Udit Singhal (University of Michigan) joins Dr. Ruchika Talwar (Vanderbilt University) to explore the evolving role of genomic classifiers and biomarkers in prostate cancer care.

---

Get the BackTable app
https://www.backtable.com/app

---

This podcast is supported by
Veracyte
https://www.veracyte.com/decipher-prostate

---

Timestamps

00:00 - Introduction
04:58 - Current State
10:07 - Interpreting High Risk Scores
13:25 - Intermediate Risk Decisions
16:18 - Imaging vs. Genomics
18:26 - Advanced Disease Evidence
22:02 - AI and Clinical Trials
29:52 - Conclusions

---

More about this episode

They review commonly used assays, including Prolaris, Oncotype Dx, Decipher, and ConfirmMDx and emphasize how these tools complement traditional clinical and pathologic risk factors. The discussion highlights practical applications across the disease continuum from initial diagnosis and active surveillance to intermediate-risk management and post-prostatectomy salvage decisions. They also explore emerging AI-driven tools and ongoing trials, highlighting the importance of contextualizing biomarker data within the broader clinical picture and using it to inform, rather than dictate, patient-centered care.

---

BackTable Urology is the go-to podcast for urologists, urologic oncologists, and urogynecologists.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app