Best Friends with Nicole Byer and Sasheer Zamata Episode: "Nicole and Sasheer's Excellent Adventure" Release Date: December 3, 2025

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In this delightfully meandering episode, Nicole and Sasheer catch up about their recent adventures together, aging and its quirks, odd self-care discoveries, musings about superhero side-hustles, and answer listener questions about friendship etiquette and bachelorette party planning. Their trademark warmth, candidness, and humor are on full display, offering listeners a joyful peek into the ongoing evolution of their friendship.

Key Discussion Points and Insights

Reliving a Wild Night Out ("The Excellent Adventure")

• Nicole and Sasheer recount their "Bill and Ted excellent adventure" night out at dinner and a bar, feeling both "so old and young at the same time." (08:13)
• Hilarity at dinner when Nicole's jokes bombed with the server, but they found levity in the acceptance at a bar called High Tops. (06:04)
• Nicole gleefully discusses running in circles at the bar to demonstrate her "speedy shoes," much to the delight of Sasheer. (07:10)

Memorable Quote:
“Sometimes bits are for other people. But, like, I love these shoes so much. I was, like...”
— Nicole (07:36)

Aging: The Good, The Bad, and the Slower Recovery

• Both discuss how aging changes their tolerance for alcohol, physical resilience, and need for longer recovery. (17:00)
• Sasheer reminisces about wild NYC nights that would “appall” her now. (17:16)
• Nicole notes, "Just because I'm not hungover does not mean I'm youthful." (08:46)
• Sasheer embraces getting older as long as she's healthy: "I feel like I’m wiser and smarter and stronger." (19:23)

Creature Comforts: Animals, Plants, and Wild Urban Encounters

• A love for pets leads to tales of Nicole's dog Clyde’s edible mishaps and postpartum dog snuggles, while Sasheer updates on neutering her cat, Trix. (12:03–16:29)
• Both share animal-run-ins at home: bird deaths, dead mouse cleanups, and raccoon antics. Nicole concludes, "Raccoons are… They’re a wild little creature." (24:02)
• Humor about who in their friend circle is called in for dead creature disposal: “Jackson scooped a bird, a dead bird out of the pool...I just can't. I can't." — Nicole (21:38)

Self-Care: Butt Facials and Lotioning Habits

• Nicole is offered a “booty facial” and ponders its purpose. Sasheer is detailed about her skincare, applying lotion everywhere, which shocks Nicole.
• “Literally everywhere. Just anywhere there’s skin, I put lotion on it.” — Sasheer (32:53)
• Nicole admits to general neglect: “I've never put lotion on my torso.” (32:04)
• Incredulous, Sasheer asks about Nicole’s routine: “Where there is skin, there is lotion.” (33:26)
• Extended conversation about shower routines, with Nicole being a “long shower-er” for deep thinking (35:59).

Home Decor & Childhood Nostalgia

• Nicole bemoans boring home trends and champions fun vintage finds—especially her “giraffe family” of brass figurines. (40:11)
• Discussion of vintage lamp hunting in NY and the virtue of “bringing color and charm” to homes. (39:29)

Superheroes—Why Do They All Work?

• A comical audit of superhero side-hustles: Superman, Spiderman, Dr. Strange, Batman (“War Stuff”), and the X-Men are all moonlighting. (44:07–48:46)
• “Honestly, that's a commentary on the economy—yeah, that they have to have a job while they're saving the world.” — Nicole (47:22)
• Sasheer on selective superhero rescue: “If I know you…if you've been nice to me.” (44:21)

Listener Questions

1. Explaining Yourself to "Delicate" Friends (55:41)

Emma writes: As a gay woman with mostly straight white male friends, how should she address their "delicate" egos when discussing her experiences?

• Nicole emphasizes repeatedly centering her story: “Well, from me and my experience…” (56:48)
• Sasheer suggests, “You might not get it because you’re not a gay lady, and that's okay…You don’t have to get it, you can just hear me.” (57:10)
• They joke about men’s unfamiliarity with certain female experiences, segueing into a playful tangent about the fragility and externality of male anatomy. (57:49–59:11)

2. Bachelorette Party Planning for Each Other (60:04)

Rebecca asks: What would Nicole and Sasheer dream up for each other's bachelorette parties?

• Sasheer: Rent a fun house—race car track, water park, or both; petting zoo; drag show; vintage shopping; ATVs. (60:07–62:29)
• Nicole: Hot dog cart, a stripper dressed as “Goofy Movie” characters Max/Roxanne, chef, cute house, brunch, and clothes optional vintage fair. (60:33–62:03)
• Both agree: “We should just do that anyway.” (62:47)

3. On Turning 40—Celebration Plans (62:54)

• Sasheer: Plans to visit Okinawa, Japan, where she was born. (62:56)
• Nicole: Wants to throw a funeral-themed party where friends give eulogies while she lounge in a casket, citing the merits of celebration while living. (63:14)
• Discussion of the logistics: “Can you rent a casket?” (63:49)
• Hilarity about “dancing pallbearers” and bottle service “popping out of caskets” at clubs. (64:28–65:16)

4. Comfortable Ending to Location-Sharing Friendships (65:34)

Writer shares pain over a drifting friendship and feeling hurt by seeing the friend traveling without them.

• Sasheer: Validates the hurt, encourages removing the friend to protect one's feelings: “For your own protection…” (67:09)
• Nicole: Suggests honesty—“I'm sorry, it wasn't a glitch. We're not as close,” and stresses, “When someone shows you they're a bad friend, they're telling you the truth.” (68:04–69:29)
• Both agree: "Un-find my friend them." (69:44)

Notable Quotes & Moments with Timestamps

• Nicole, on running off at the bar:
  “You didn’t even look back to see if I was watching. She was just going.” (07:10)

• Nicole, on not being in her 20s anymore:
  “I started laughing because I was like, well, I’m not hungover. I feel like I’m in my 20s again. And then had to rest my head against the shower and I went, I’m not in my 20s.” (08:36)

• Sasheer, on pets high on edibles:
  “Animals when they're high are pretty funny. Don't know what's going on.” (14:40)

• Nicole, on superhero economics:
  “Honestly, that’s a commentary on the economy… that they have to keep a job for income while they're saving the world.” (47:22)

• Sasheer, on being a people-pleaser:
  “But I’m definitely not going to stay out if I don’t want to. I’m not like, Nicole needs me to stay out here, so I gotta stay. No. I’ll go home if I’m tired.” (54:44)

• Nicole, reflecting on friendship honesty:
  “When someone shows you they’re a bad friend, they’re telling you the truth.” (69:29)

Timestamps for Important Segments

• [06:04] Nicole’s dinner joke fails & bar stories
• [07:10] Nicole demonstrates her speedy shoes
• [08:46] Not being young just because not hungover
• [12:03] Reunited with dog Clyde, pet stories
• [14:43] Pets and accidental edible ingestion
• [19:23] Embracing the wisdom of aging
• [32:04] Skincare routines: the “full body lotioning” debate
• [39:29] How to bring color and charm back to homes
• [44:07–49:09] Superheroes and their side jobs
• [55:41–57:34] Advice on delicate friends and sharing from personal experience
• [60:07–62:50] Bachelorette party dream planning for each other
• [63:14] Nicole’s 40th birthday funeral plan
• [65:34–69:59] Ending location sharing with a drifting friend

Tone and Vibe

The episode is a relaxed, meandering, and joyfully candid conversation between longtime friends. Nicole and Sasheer are self-effacing, warm, sometimes mischievous, and openly affectionate—never shying away from gentle ribbing, personal sharing, or big, silly laughs.

Conclusion

This episode is quintessential "Best Friends": candid, funny, occasionally poignant, with discussions that swing between the ridiculous (raccoon gymnastics, butt facials, superhero jobs) and the genuinely helpful (friendship advice, self-care routines, open conversations about growing older and changing priorities).

Whether reminiscing about wild nights out, musing about moisturizers, or offering wise and witty advice to listeners, Nicole and Sasheer deliver a soulful and laugh-out-loud weekly ritual of friendship.