In this episode of Bowel Sounds, hosts Drs. Amber Hildreth and Jason Silverman talk to Dr. Saul Karpen, the inaugural chief scientific officer for the Stravitz-Sanyal Institute for Liver Disease and Metabolic Health at Virginia Commonwealth University, Richmond, Va., where he is a professor of internal medicine and adjunct professor in pediatric medicine at the VCU School of Medicine. We talk about new genetic discoveries in biliary atresia and the future goals of research on this important pediatric liver topic.

Learning objectives

Describe the pathophysiology of biliary atresia
Understand the importance of early screening and new tools to assist in early detection
Examine the newly discovered genetic etiology to biliary atresia

Links:

Guidance for the Primary Care Provider in Identifying Infants with Biliary Atresia by 2-4 Weeks of Life: Clinical Report

Bilitool.org

Liver-Restricted Deletion of the Biliary Atresia Candidate Gene PKD1L1 Causes Bile Duct Dysmorphogenesis and Ciliopathy

Stravitz-Sanyal Institute for Liver Disease and Metabolic Health

AASLD

Previous Episodes Mentioned:

Bill Balistreri- Neonatal Cholestasis

Jorge Bezerra- Advances in Biliary Atresia

Disclosures:

Dr. Karpen has a non-reimbursed consulting relationship with Ipsen as BOLD PI

Dr. Hildreth serves as a consultant and speaker for Ipsen

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