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Dr. Sanjay Gupta
Now the days are getting shorter, the weather is getting colder. I actually really love this time of year. Many of us are gathering more than usual with loved ones and coming together to share a cozy meal, some comfort food. But in the back of our minds, we probably also know those comfort foods aren't the healthiest for us. So the question we have today is what if those comfort foods could actually help us live longer and healthier lives? Okay, I know what you're thinking. Healthy comfort foods, recipes that promote longevity. It's probably not going to taste very good, right? It's probably going to be pretty bland. I get it. Healthy eating doesn't always have the tastiest reputation. But that's exactly why I invited my good friend Dan Buettner, who has spent decades studying the world's longest living people, to join us on the podcast today.
Dan Buettner
These simple peasant foods taste maniacally delicious.
That's the word I like to use.
Dr. Sanjay Gupta
Maniacally delicious.
Interviewer (possibly Dr. Sanjay Gupta or another host)
I love that.
Dr. Sanjay Gupta
And Dan would know. He's a world explorer and National Geographic fellow and he's also the best selling author who helped coin the term that you have certainly heard. Blue zones. These are places around the globe where people live the longest and healthiest lives. Now in case you're curious what Dan has been up to recently. Well, for the last three years he's been working with researchers at Stanford to reverse engineer what flavors Americans like and then applying what he's learned from the diets of these blue zones. It all resulted in a new cookbook called the blue zones kitchen one pot 100 recipes to live to 100. And it is more than just recipes I can tell you. I've read the book. My my wife has post it notes.
Interviewer (possibly Dr. Sanjay Gupta or another host)
All over the book.
Dr. Sanjay Gupta
I showed Dan. He was delighted. And today I sat down with Dan to talk about why taste matters more than willpower. What ingredients should you be incorporating into your diet and how this could all help you live longer. I'm Dr. Sanjay Gupta, CNN's chief medical correspondent and this is chasing.
Dan Buettner
Foreign.
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Interviewer (possibly Dr. Sanjay Gupta or another host)
You're this guy who's traveled the world, you're a world champion cyclist, but all these things sort of going on. You come across these places as part of your exploration where people are living these extraordinarily long lives. Do I have that basically right? I mean, how did this start for you?
Dan Buettner
Out of college, when you were going to medical school and doing productive things? I set three records for biking across five continents. Alaska, Argentina, around the world and across Africa. But my true impetus was an appetite for discovery. I decided in the same way that you've had the epiphany that you wanted to take your talents and channel them into medicine and then sharing the insights with the masses. My sense of purpose is exploring, but.
Not just for my own personal interest.
But in a way that I can bring back something that's useful for others. I was really interested in expeditions that would really help people live better. And longevity seemed to be the right idea. Now actually the first blue zone we found in Okinawa, Japan, right. That was really the result of a World Health Organization finding that showed that those people enjoyed the longest disability free life expectancy in the world. I said that's a great mystery. And took a team there in 1999 and really just caught the bug. The first place called a blue zone. Gianni Pass, who's still a great friend till this day. In fact, we just found a new blue zone last month. He does a very sophisticated analysis of population data. It starts with something called mortality rate. So he finds these place with unusually low mortality, which also means you have a much higher concentration of centenarians over time. And in those villages that reach a certain threshold. He put a blue dot on a map. And I've seen the map. It's just a map on a piece of paper.
And there were so many blue dots.
In one area in Sardinia, area called Oliostra in the mountains, that he just started calling it the blue zone because of the blue cloud. And that's where the name comes from.
But the idea actually originates a few.
Years earlier with this idea which came a National Geographic article to find the areas around the world where people live the longest statistically Speaking and then find their common denominators.
Interviewer (possibly Dr. Sanjay Gupta or another host)
It's such a fascinating story, and it's such a relevant story to everybody because you're talking about places around the world where people live these extraordinarily long lives, and then trying to figure out, you know, what the insights are for the rest of us, you know, this has.
Dan Buettner
Never been a personal quest, and nor do I fashion myself a longevity guru. I like to think of myself as more a translator or a bridge to these cultures that really have a lot to offer us.
Interviewer (possibly Dr. Sanjay Gupta or another host)
I imagine it's got to impact the way you live, though.
Dan Buettner
It does, yes.
Interviewer (possibly Dr. Sanjay Gupta or another host)
In terms of your diet choices, your activity choices, what are some examples of things that maybe you've changed over the last 20 years?
Dan Buettner
I stopped eating meat because it's very clear the cultures of longevity are very low meat eaters.
They're eating peasant food, really.
So I've learned how to make peasant food taste good. And that's my diet, usually whole food, plant based. I understand the enormous power of knowing.
Your sense of purpose, Waking up every.
Morning, not with the existential stress of what do I do with my life. And so I'm very clear about how I spend my days. It's ballast in times of uncertainty, and it makes decision making very easy. When you know that we all know how stress shaves ears off your life. I know the incredible power of having the right social circle around you.
Interviewer (possibly Dr. Sanjay Gupta or another host)
Yeah.
Dan Buettner
If you hang out with people who smoke or drink too much or sit around and complain, that's all measurably contagious as is. You know, I'm sort of a pickleball fanatic and a bicycling fanatic. So I kind of hang out with those people. And the biggest thing, Sanjay, when it.
Comes to longevity, and this is a, you know, 20 years of work in.
In finding and examining these places where people live long boils down to one phrase.
If you want to live longer, don't.
Try to change your behavior because you'll probably fail in the long run.
Change your environment.
So I very intentionally, you know, I live in the southern tip of South Beach, Florida. I'm right on the water.
I swim almost every day.
I. I live in a walkable neighborhood. I live in a place where I'm bumping into my neighbors all the time. So I have great social equity around me. That's a food environment where it's easy to get healthy food. And so I mindlessly live a healthy lifestyle. It's not, you know, I'm not over there weighing my protein powder or Counting how many reps I do down in the gym, I just go live my life.
Interviewer (possibly Dr. Sanjay Gupta or another host)
What I've always loved about your work is that you've gone to these places where people are living long lives. So it's not to say, hey look, let's try this so you can live a long life. You've said, let's travel the globe, see where people are living long lives, what is accessible about their lifestyles for people back in the States or other parts of the world. And maybe you learn and maybe you adopt those things. And that has always seemed very sensible to me. So I, I really appreciate that. And every time I talk to you, I just want to emphasize that for the audience because again, I think most of the people listening are well intentioned. They want to do right by their health, they want to do right by the health of their loved ones. But you know, you got to beware and understanding that there are people around the globe who live these lives that you emulate. Dan Buettner's done the work. He's gone and seen what those lives are like and we can all learn from it.
Dan Buettner
I have, yeah, I know the images. It's like Dan Buettner in a backpack going to these places. We actually spent three years with a team of demographers, five demographers who've written peer reviewed articles to first parse through worldwide population data with the signal is low mortality rate.
And then we actually go there and.
Look at birth records and death records over 150 years and we confirm these.
Places people are living the longest.
The metric we use is not only concentration of centenarians, but also life expectancy at age 70. This seems to be the most interesting marker. Then we started looking what are the common denominators. And you know what Sanjay? That someone our age, which is 60, they enjoy about 10 extra years of life expectancy at age 60, not at birth, at birth. It's extraordinary as well. In some of these areas, about a 15 fold better chance of reaching age 100. These are real people with an average set of genes. They don't have any special genes. They're heterogeneous populations. And the way they achieve it are things that I can't make any money off of you. They grow their own food, they sit down to dinner with their family, they take naps, they have a spiritual life that they actually show up for. They walk places, they know their neighbors, they value their friendships. And these are things, if you look at the academic literature, you're going to see that every one of these things. There are studies done that show they yield higher life expectancy, but they're not popular. They're not, they're not quick fixes. They're not, take a pill, monetizable, monetizable. So that I don't get nearly as much publicity pop. But I've been around for 25 years and I have kind of a slow, steady increase in, in population recognition. You know, I speak at the same conference that all these biohackers are, and my audiences are just as big as theirs. And I think it's counterbalances some of the more hyperbolic approaches to longevity. And eventually people come, come around.
Dr. Sanjay Gupta
Up next, how Dan used artificial intelligence to determine America's favorite flavors. Turns out we are pretty predictable. Then he translated those favorite flavors into longevity boosting one pot meals.
Interviewer (possibly Dr. Sanjay Gupta or another host)
We'll be right back.
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Interviewer (possibly Dr. Sanjay Gupta or another host)
I want to talk mostly about your cookbooks. My mom wanted me to ask you if she were to adopt many of these things, start doing the one pot meals, things like that, how much benefit could she get now at age 80, do you think?
Dan Buettner
Three years of life expectancy and that isn't just off the top of my head. That was a very good meta analysis done out of Bergen, Norway. Followed the equivalent of about 6 million people for 30 years and found that people who are eating the standard American diet can expect at age 83 fewer years than somebody who's following largely a whole food plant based diet. And so yeah, and at 60, by the way, at six years and at 20 for a male it's about 12 years. For a female it's about 10 years. So these are very real gold standard epidemiology that just reaffirm what I've observed in blue Zones, but in a more concrete way. The last book that just came out, also New York Times bestseller, is called Blue Zone Kitchen One Pot Meals. And I made that. We did not go back to the blue zones for those recipes because a lot of recipes aren't one pot in the blue zones. I teamed up with Johannes Eichstad from Stanford and his AI lab and we examined 675,000 recipes and we isolated all the recipes with 100 or more five star reviews. We knew that Americans love these recipes and we analyzed them for the patterns and we found that most of the most popular recipes in America follow one of seven different patterns. And then we kind of reverse engineered deliciousness so we, we knew the ingredients of longevity, then we know the patterns or, or the palates, the combinations Americans loved. And then I got one of the best recipe developers in America to work with me to, under These guidelines, build 100 recipes to live to 100.
Dr. Sanjay Gupta
Did any of this surprise you?
Interviewer (possibly Dr. Sanjay Gupta or another host)
I mean, like in terms of what the, the top five star recipes were, like what we, what we actually eat?
Dan Buettner
Well, here I, I'll read them to you right now. So these are the America's favorite taste. Stir fries and curries. Not so surprising. Tex Mex flavors. Not so surprising.
Dr. Sanjay Gupta
Chilies.
Dan Buettner
And so much traditional Italian flavors. Not so surprising. Cheese. Now that was a hard one. How, how do you people like cheesy things? Well, it turns out with nutritional yeast and a few other ingredients, you can mimic the taste of cheese and the creaminess. You, you take cashews, you soak them for a while, you put them in a Vitamix, it creates something virtually indistinguishable from whipping cream. And you mix that with brewer's yeast and you get something that tastes like a cheese. And you can make a Mac and cheese out of another very interesting, very surprising combination. Broccoli and mushrooms. Now you know the Tex Mex, duh. But broccoli and mushrooms, lemon and herbs, that's something that the Greeks give us, that this combination of lemon and herbs. And then an overall kind of rule to make people love a food is to make them spiky. People like sort of intensities of sensations. The best example is an Oreo, an oriole, the outer part is a little bit bitter, you know, the cacao, that dark chocolate and crunchy, and the inside is soft and sweet and comforting. And it turns out Americans love that. They call it high tension foods that, that crunch and that ooze. So we created something called the Three Sisters Pot Pie, which has beans in There squash, which is a little bit crunchy. But then we put it in a pie. Soft, comforting, savory filling. But then that wonderfully homey pie crust on the outside so created that tension.
Interviewer (possibly Dr. Sanjay Gupta or another host)
How, how much did you use things like, like AI to help? Because if you, if you have these patterns of, of palette preference, you know, as you, as you outlined and you want to create the, the, you know, the one pop meal, can you get big, you know, platforms like AI to just do this for you or what did you do?
Dan Buettner
Well, we used an AI, Stanford AI lab that we actually used them, the terminology. We scraped the recipes and then we analyze them. We had PhD AI researchers doing the analysis. And then with the outcome, it just gave us the intel to know what kinds of recipes are likely to be very popular with Americans. And yes, we do.
Yeah, it was kind of a marriage.
Between the AI and the traditional. In a way, you know, that honored tradition. It honored these recipes of longevity or at least these ingredients of longevity. In a way Americans would eat them.
Interviewer (possibly Dr. Sanjay Gupta or another host)
I hope everyone puts this book in their kitchen, you know, because you obviously will have a quick guide to making a quick one pot meal. But also there's a lot of learning in there about these ingredients in the book as well. You focused on one pot meals. That's in the title in this latest book.
Dan Buettner
Why that we have these blue zone project cities that the entire city takes on an effort to increase their health and longevity. And, and when you're trying to convince a city to eat this way, when you have the competition from fast food and ultra processed food, one of the biggest objections you're going to get is I don't have time. Number two, I don't, I can't afford it. Number three, I don't know how to do it. Number four, I don't think it'll be delicious. So the idea of one pot, you know, everybody's got a pot and, and if they don't have a pot, I suggest getting an instant pot. I have nothing to do with the company, but it's just a quick way to make food. And so I started with this criteria that every recipe had to take less than 20 minutes to combined. It had to cost less than 3 bucks a serving and it had to be maniacally delicious. And I think we checked all those boxes and I really believe we are not going to turn around the obesity epidemic in the country. About 75% of us are overweight or obese until we start cooking at home. Because every time we go out to eat, we consume an extra 300 calories. Those calories tend to be laden with sodium, added sugars. Ultra processed food at home, we can control the ingredients. As long as you can give people the hardware and the software in an affordable fast way, I believe we can get people back in the kitchen creating real health for their families.
Interviewer (possibly Dr. Sanjay Gupta or another host)
And should point out you said this a couple times, but taste is a big part of this for you. I mean, in fact, I think you said taste is the number one longevity ingredient. Right. If it's not tasty, people aren't going to eat it.
Dan Buettner
That's right, yeah, there are, you know, 2 or 3% of people are vegans and they care about animal cruelty. Maybe 15% of people really are kind of cognizant of the environment, the carbon footprint of what they eat. Maybe a quarter of people think about their health when they eat, but at the end of the day when lunch rolls around, they want something delicious and that's going to carry the day. And if the only thing there is a burger, they're going to eat the burger nine out of 10 times. So we're not going to beat these ultra processed foods until we create whole food alternatives. And I'll just offer a data point which is also a plug. We created these blue zone kitchen frozen meals, 100% whole food plant based, formulated for longevity, maniacally delicious about two years ago and they're now the top selling frozen food in many categories.
Interviewer (possibly Dr. Sanjay Gupta or another host)
Right. By the way, congratulations on that. I mean all these books that you've written, these products that are making people healthier.
Dr. Sanjay Gupta
Good.
Interviewer (possibly Dr. Sanjay Gupta or another host)
And again, I hope people who are listening to the podcast understand where this is all coming from, the inspiration, the backstory here. Plant based versus meat. Now, you know, in some of these blue zones people do eat some meat. The book is entirely plant based. Tell me about that thinking.
Dan Buettner
Well, people in blue zones do eat meat, except for the Seventh Day Adventist in Lomalina, are mostly vegetarian. But it's the quantity. Americans eat about 220 to 240 pounds of meat per year. And there's just no question that's driving cancers of the GI tract, cardiovascular disease and even type 2 diabetes. In blue zones. They're consuming less than a tenth of that, about £20 a year of meat. And meat is celebratory food there. I personally don't believe there's anything wrong with eating meat once a week or something. That's people in the blue zones do. But when it's bacon for breakfast, a burger for lunch and a pork chop for dinner, that's when you start getting in trouble. I'm no longer a vegan, but I lived among vegans for about 10 years. Very healthy Olympic level athletes, bodybuilders that never ate a piece of meat. So you can get all the protein you need from plant based sources. And, but, but, and by the way, you also get your fiber. And that's what we should be focusing on. That's why I wrote these books to be 100% whole food plant based because you're also going to get your fiber and you're going to get your phytonutrients and, and your antioxidants that you don't get from meat, eggs or cheese.
Interviewer (possibly Dr. Sanjay Gupta or another host)
What is your new book about that you're working on?
Dan Buettner
So the new Blue Zones. So the old blue zones are, are being overtaken by the standard American diet and cars and networked electronics. Meanwhile, there's new places where longevity is emerging. And mostly they're manufactured Blue Zone. There's places where really enlightened leadership has created populations where people are enjoying 12 good years longer than we are enjoying in America. And in the same strategy I use with the original Blue Zone, we found the data to identify these pinnacles of healthspan. And then I first did a complete literature review to understand what's going on in these places and then traveled there, talked to the top experts, found good people represent these cultures of healthy longevity. And the book is about the common denominators of places where people are living the longest lives without disease and without major disability.
Interviewer (possibly Dr. Sanjay Gupta or another host)
When we spoke, I think last year you were talking about Singapore. Is that one of those places?
Dan Buettner
Singapore is one of them, yes. It's not the one I'm profiling this book, but I did a Netflix series called live to 100 which won three Emmy awards. I only say that because people are more likely to watch it. Lived to 100 Secrets of the Blue Zones. They needed a new Blue zone and I knew Singapore very well. One of these places where people are living about 10 years longer, 10 more good years longer than Americans. And, and I named it a new Blue Zone and deconstructed it a little bit for people to help them understand what sorts of things really drive longevity. And it's not what we think.
Interviewer (possibly Dr. Sanjay Gupta or another host)
The world has gotten to know you. I am really just honored that you join us on the podcast. The book. This is a book that everyone should have in their kitchen. You just have it because you can quickly pull it out as a reference and you can pick out a meal takes 20 minutes, 3 bucks a serving but it comes from all the topics, all the learnings from a guy who has, you know, traveled the world, you know, really developing these things. So we're all better because of it. So thank you, Dan. Thanks for joining us.
Dan Buettner
It's an honor, Sanjay. And for all the people listening, thank you very much. I hope to see you all when you're 100.
Interviewer (possibly Dr. Sanjay Gupta or another host)
Love it. I'll be there with you. I'll be there with you.
Dr. Sanjay Gupta
That was my conversation with author, explorer, National Geographic fellow and friend Dan Buettner.
Interviewer (possibly Dr. Sanjay Gupta or another host)
Thanks so much for listening.
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Episode Title: What If Comfort Food Could Help You Live to 100?
Guest: Dan Buettner, National Geographic fellow and best-selling author
Release Date: November 21, 2025
In this engaging episode, Dr. Sanjay Gupta speaks with Dan Buettner, a renowned explorer and originator of the "Blue Zones" concept, about how comfort foods — typically seen as unhealthy — can be reimagined to enhance longevity and quality of life. The conversation delves into Buettner's decades of research on the habits of the world’s longest-living populations, practical strategies for changing our food environment, and the creation of delicious, plant-based comfort foods that support healthy aging. The episode is rich with stories, scientific insights, and actionable tips.
Host: Dr. Sanjay Gupta
Guest: Dan Buettner
For more stories and practical longevity tips, check out Dan Buettner's cookbook, "Blue Zones Kitchen: One Pot, 100 Recipes to Live to 100," and the Netflix series, "Live to 100: Secrets of the Blue Zones."