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Dena Temple Rouston
From Recorded Future News and PRX, this is click here.
Dr. Stephen Xenakis
I'm a psychiatrist, spent 28 years in the Army. I came in 1970, retired 1998 as a brigadier general, working with military families and veterans and do a lot of public health activity as well.
Dena Temple Rouston
You know what?
Unknown
You forgot your name.
Dr. Stephen Xenakis
Oh, Stephen. No, I'm Steven Tsunakis.
Dena Temple Rouston
From Recorded Future News, this is Click Here's Mic Drop, a longer cut of one of our favorite interviews of the week. I'm Dena Temple Rouston. So when you think of a psychiatrist, you probably have a picture in your head, calm demeanor, notebook, pen maybe, sitting across from a patient who's stretched out on a chaise lounge, nodding, taking notes, classic Freudian stuff. But Dr. Stephen Xanakis is not exactly that kind of psychiatrist. For starters, he's a retired brigadier general in the army, so he deals with a different kind of patient. He's worked with detainees at Guantanamo Bay. He's advised top military officials on the impact of blast wave concussion. And he's the kind of psychiatrist who is not afraid to go against the grain and try new things. For example, he's a big proponent of psychedelic therapy for ptsd, something that for a long time was considered kind of out there. And more recently, he's been thinking about this other thing he'd like to try to incorporate into his practice.
Dr. Stephen Xenakis
I've been for years thinking that we needed to use these AI tools in identifying patients who would best respond to particular treatments.
Dena Temple Rouston
Stay with us. Support for Click Here comes from Curiosity Weekly, a podcast from Discovery. Each episode unpacks breaking science and tech news with experts who can make sense of it all. Recent episodes have covered what neuroscientists have learned from TikTok, how AI manages to read hieroglyphics, and whether today's robots can actually feel pain. All things I've wondered about on Curiosity Weekly from Discovery makes sense of some of the biggest questions and ideas shaping our world. You can listen wherever you get your podcasts. Click Here is brought to you by Progressive Insurance. You chose to hit play on this podcast today. Smart choice. Make another smart choice with Auto Quote Explorer to compare rates from multiple car insurance companies all at once. Try it@progressive.com Progressive Casualty Insurance Company and affiliates. Not available in all states or situations. Prices vary on how you buy. I'm Dina Templewurst, and this is Click Here's Mic Draw. Stephen Xenakis often spends the day navigating the fragile terrain of the human mind. His patients include veterans, men and women who have seen war up Close and have lived through things most people never even have to imagine. Now, these veterans are home. But home isn't always a place you can simply return to. And they're struggling. Maybe they can't sleep, maybe their nerves are on edge, their thoughts racing. So they come to see him. Unlike most psychiatrists, Xanakis listens. He diagnoses, he prescribes medication when needed. He helps his patients develop coping strategies. Now, psychiatry has always been part science, part detective work, and part deep human connection. And these days, Xanakis is starting to explore how AI might be used as a way to sort of amplify his expertise, to help him diagnose and personalize treatment.
Unknown
Can you give me a hypothetical of.
Dena Temple Rouston
How it would work?
Dr. Stephen Xenakis
Well, the hypothetical would be, and we have tested this out, is that a patient comes in, let's say a veteran. And we know that these veterans have multiple problems. They've got ptsd, many have been exposed to trauma, and they have traumatic brain injury. They have had other injuries, so they've got chronic pain. They may have sleep problems. They may have been exposed to medications that have also made them feel more anxious or caused thinking problems. And they come in for an interview and they say, look, I need some help here.
Dena Temple Rouston
So how do you figure out what this person needs? The traditional response was use a questionnaire, fill in some bubbles, rate your mood on a scale of 1 to 10, things like that. But Dr. Zenakis says, no, that's just not enough.
Dr. Stephen Xenakis
We're getting away from questionnaires. That's what I'm trying not to do. I think questionnaires, excuse me, I think are too crude. That's standard in the field. But I don't think they get the kind of nuanced subtleties that we get just from an interview.
Dena Temple Rouston
What Dr. Xenakis would do instead of multiple choice questions, is a more open ended kind of interview with the patient.
Dr. Stephen Xenakis
It would just be a raw interview that could be uploaded and compared to what we think is our reference interview or our sentinel. And how close is the correspondence? And because of the way these large language models work, they're able to find key words and nests of words that show what the correlation is. So this goes way beyond, it's quantum leaps beyond a questionnaire.
Dena Temple Rouston
So this is the idea, not just forms, not just checklists, but something closer to the way real conversations work. And then AI would help doctors scan those conversations and pick up on things that might otherwise get missed. Maybe just some nuance that got lost in the shuffle of a long conversation, or it could be something that a psychiatrist just doesn't have expertise in, but the AI has been programmed to understand. Dr. Zanakis says his interviews with patients would be structured in a way to actually help the AI.
Unknown
So would there be set questions so that you could compare apples and apples?
Dr. Stephen Xenakis
Just a good clinical interview? I mean, I think good clinical interviews have set questions. I mean, what is the problem? How serious is it? How long have you had it? You know, what other problems do you have like this? I mean, what's the history have you had? I mean, it's just a good clinical interview, right?
Unknown
Are you sleeping? Which is usually a pretty good one.
Dr. Stephen Xenakis
Yeah, exactly.
Unknown
To tell if something's off. I see.
Dena Temple Rouston
Pairing these kinds of structured interviews with AI, he says, could take the doctor patient relationship out of multiple choice and into something he thinks would be, well, deeper. Which raises the question, could technology, something that feels cold and impersonal, actually help make mental health care more human? And do we even want it to stay with us?
Matt Galloway
When was the last time you said, hmm, I never thought about it that way? The Current aims to give you that moment every single day. Hello, I'm Matt Galloway, and our award winning team brings you stories and convers to expand your worldview. Sometimes they connect to the news of the day, sometimes to the issues of our time, and you'll hear all kinds of people on the Current, from bestselling authors to maybe your neighbor. Find us wherever you get your podcasts now, including YouTube. I'll talk to you soon.
Dena Temple Rouston
So imagine you're a psychiatrist in a small town, maybe in Wyoming, maybe Alaska. You've got veterans coming into your office, and some are struggling with ptsd, others with pain that just won't go away. And they need your help. But you don't have a huge team. Instead, you have a backlog of patients and not a lot of resources to go around. What Dr. Xenakis hopes AI can do is give doctors access to something that could both extend their expertise and make the treatment process more efficient by connecting doctors to a system that could take every interview, every conversation they've had, and compare it to thousands, maybe hundreds of thousands of other conversations.
Unknown
Are there particular places where you think this would be particularly helpful?
Dr. Stephen Xenakis
I mean, look, I think it'd be particularly helpful outside of our urban areas, places where we don't have a good number of mental health people, and yet we have a number of patients that are really seeking help in the military.
Dena Temple Rouston
There's a term for this kind of thing. It's called a force multiplier. A Force multiplier is anything, a weapon or a tool that lets soldiers do more than they could do on their own. It essentially amplifies their abilities. And Dr. Xenakis, he says AI could be a force multiplier for doctors.
Dr. Stephen Xenakis
I know that there are many therapists out there that are in communities and may not have had a lot of experience.
Dena Temple Rouston
And the numbers are kind of shocking. In states like Alaska and Wyoming, veterans make up at least 10% of the population. But the number of psychiatrists in these states, well, for the roughly 1.3 million people, there are less than 200 registered psychiatrists in both Alaska and Wyoming combined. Psychiatrists in rural areas are strapped not just for resources, but for patient data to refer to. But a large language model could essentially expand the amount of patient data they can draw from to help guide their patient care.
Unknown
And then what they would be able to do is, with a large language model, it would be compared with thousands, maybe hundreds of thousands of other patients. So that you'd be using all that knowledge to come up with a solution.
Dr. Stephen Xenakis
Yeah, exactly. And then it would learn over time, so we would be able to feed that back. The more we do that, the more we learn. And we say that, for example, a patient's prescribed a particular medication that we think would help with sleep. Well, as we look at that and look at those patients who were prescribed and look at their interviews, we can get a better idea of who would be a responder. And that's really important.
Unknown
Right, so that they don't take a.
Dena Temple Rouston
Pill that doesn't end up helping their problem.
Dr. Stephen Xenakis
Yes, right.
Dena Temple Rouston
Because even with a great interview, even with the best doctors, no one gets everything right. But maybe with enough data, they could get closer. So let's be honest. Anyone who's ever gone to a doctor has probably fudged a thing or two. You say you exercise a few times a week, but really, was it twice? Once, not at all. You tell your doctor you sleep okay, but if they asked you how many hours, how much was deep sleep versus light sleep, you wouldn't really know. Xanakis knows this. He knows that some of the information he gets from his patients isn't exactly, well, precise.
Dr. Stephen Xenakis
It's really hard to get good information from your patients about how well they slept or really did they exercise? Not that any of this intentionally being misrepresented or, you know, that they're not intentionally not disclosing to us. I mean, how well did you sleep? I don't know.
Dena Temple Rouston
But now we don't have to guess about some of those things because we have wearables. So think about something like an Apple Watch or a Fitbit. It tracks your heart rate. It knows how many steps you take. It even knows down to the minute how much deep sleep you got last night. And when doctors have access to that kind of data, it changes the game.
Dr. Stephen Xenakis
So let's look at that and then let's look at what you did, or let's look at your diet. And the more we have that and we can look at it together, the better decisions we can make. And then we can decide what treatments might work best with you as we think about either medicines or activities or cognitive behavior therapy.
Dena Temple Rouston
Because mental health isn't one size fits all. What works for one person might not work for another. But AI, these wearable devices and the technology being developed now, Dr. Sinakis says this is a real turning point, a way to customize treatment better and get past the guesswork.
Unknown
So I just got a new Apple Watch. And so I have it tracking my sleep because I was interested. I'm not really interested in all the exercise stuff and heart rate and all that other stuff, but I'm finding myself being quite obsessed with how much deep sleep versus core sleep versus REM sleep, how much I'm awake. And it is, as you say, something.
Dena Temple Rouston
I would never be able to tell a doctor.
Unknown
I could just say, okay, I feel pretty rested, I guess, but this is showing me just how much it is.
Dr. Stephen Xenakis
Yeah. And I think it's very. I mean, I know that people get obsessed with it, but I think it's really helpful. I use it a lot with my.
Dena Temple Rouston
Patients using technology in psychiatry. It sounds futuristic, maybe even revolutionary. The rub is that psychiatry isn't an equation. It isn't about solving for X. It's about people. And people can be messy. And then there's this bigger question. Is this what we really want? Sure, AI has its place. It can help with paperwork, maybe spot early warning signs. But psychiatry isn't just science. It's an art. And AI isn't an artist. At least not yet. From recorded future news, this has been Click Here's Mic Drop. It was written and produced by Erica Gajda, Megan Dietri, Sean Powers and me, Dina Temple. Rest. It was edited by Karen Duffett. We'll be back on Tuesday with an all new episode of Click Here. Have a great weekend.
Unknown
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Podcast: Click Here
Host: Dena Temple-Raston
Guest: Dr. Stephen Xenakis
Release Date: February 7, 2025
In this episode of Click Here, host Dena Temple-Raston delves into a compelling conversation with Dr. Stephen Xenakis, a retired Brigadier General and seasoned psychiatrist with 28 years of service in the Army. Dr. Xenakis has dedicated his career to working with military families, veterans, and detainees at Guantanamo Bay, addressing complex mental health issues such as PTSD and traumatic brain injuries.
Notable Quote:
“When you think of a psychiatrist, you probably have a picture in your head, calm demeanor, notebook, pen maybe, sitting across from a patient... But I’m not exactly that kind of psychiatrist.” – Dr. Stephen Xenakis [00:37]
Dr. Xenakis challenges the conventional image of psychiatry by highlighting his unique experiences and approaches. Unlike the stereotypical psychiatrist, his work spans high-stress environments and involves innovative treatments, including advocating for psychedelic therapy for PTSD— a method once considered fringe in the field.
Notable Quote:
“I’m a big proponent of psychedelic therapy for PTSD, something that for a long time was considered kind of out there.” – Dr. Stephen Xenakis [00:37]
A significant portion of the discussion revolves around Dr. Xenakis's vision of incorporating Artificial Intelligence (AI) into psychiatric practice to enhance diagnostic accuracy and personalize treatment plans. He envisions AI as a tool to parse through complex patient data, enabling psychiatrists to identify the most effective treatments for individual patients.
Notable Quote:
“I’ve been for years thinking that we needed to use these AI tools in identifying patients who would best respond to particular treatments.” – Dr. Stephen Xenakis [01:51]
Key Points:
Beyond Questionnaires: Dr. Xenakis criticizes traditional questionnaires for their lack of depth and advocates for open-ended interviews that AI can analyze for nuanced insights.
“We’re getting away from questionnaires. That’s what I’m trying not to do... It’s quantum leaps beyond a questionnaire.” – Dr. Stephen Xenakis [05:37]
AI as a Force Multiplier: Especially in rural areas with limited psychiatric resources, AI can act as a force multiplier, enhancing the capabilities of existing psychiatrists by providing access to extensive patient data and comparative analysis.
“AI could be a force multiplier for doctors.” – Dr. Stephen Xenakis [09:58]
Dr. Xenakis outlines a hypothetical scenario where AI assists in diagnosing and treating veterans suffering from multiple overlapping conditions such as PTSD, traumatic brain injury, chronic pain, and sleep disorders. By analyzing patient interviews against a vast database of similar cases, AI can identify patterns and correlations that may inform more effective treatment strategies.
Notable Quote:
“It would just be a raw interview that could be uploaded and compared to what we think is our reference interview... It’s quantum leaps beyond a questionnaire.” – Dr. Stephen Xenakis [06:03]
Examples Discussed:
Personalized Medication: AI can help determine which medications are likely to be effective for specific patients, reducing the trial-and-error approach often associated with psychiatric treatment.
“We can get a better idea of who would be a responder. And that’s really important.” – Dr. Stephen Xenakis [11:22]
Wearable Technology Integration: Incorporating data from wearables like Apple Watches or Fitbits can provide objective measurements of patients' sleep patterns, activity levels, and physiological responses, which the AI can analyze alongside interview data to inform treatment.
“With wearables, we have data that can change the game.” – Dena Temple-Raston [13:09]
Notable Quote:
“The more we have that and we can look at it together, the better decisions we can make.” – Dr. Stephen Xenakis [13:30]
While the integration of AI presents exciting possibilities, the conversation also touches on the inherent challenges of blending technology with the deeply human art of psychiatry. Dr. Xenakis acknowledges the potential for AI to enhance efficiency and accuracy but remains mindful of maintaining the essential human connection in therapeutic settings.
Key Points:
Balancing Technology and Humanity: Psychiatry is not just a science; it’s an art that requires empathy and human insight, areas where AI currently lacks proficiency.
“Psychiatry isn’t just science. It’s an art. And AI isn’t an artist. At least not yet.” – Dena Temple-Raston [14:51]
Data Accuracy and Patient Honesty: Dr. Xenakis recognizes the limitations of patient self-reporting and how objective data from AI and wearables can mitigate inaccuracies in patient-provided information.
“It’s really hard to get good information from your patients about how well they slept.” – Dr. Stephen Xenakis [12:47]
Dr. Xenakis envisions a future where AI significantly augments psychiatric care, particularly in underserved areas. By leveraging large language models and extensive data sets, AI can provide psychiatrists with deeper insights, leading to more personalized and effective treatment plans. This technological advancement promises to bridge gaps in mental health care accessibility and quality, transforming how psychiatric services are delivered.
Notable Quote:
“This is a real turning point, a way to customize treatment better and get past the guesswork.” – Dr. Stephen Xenakis [13:51]
Final Thoughts: The episode underscores the transformative potential of AI in psychiatry while emphasizing the need to preserve the human elements that are crucial to mental health care. Dr. Xenakis’s innovative approach highlights a future where technology and human expertise collaborate to enhance patient outcomes.
Credits:
Mic Drop: The Algorithm Will See You Now - AI and Psychiatry was written and produced by Erica Gajda, Megan Dietri, Sean Powers, and Dena Temple-Raston, with editing by Karen Duffett.
Listen to More Episodes:
Stay tuned for more insightful conversations every Tuesday and Friday on Click Here, where Recorded Future News brings you true stories about the people shaping our digital world.