
Hosted by Core IM Team · EN
Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges

What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on medication timing around dialysis, drug dialyzability, antihypertensive selection, and strategies to prevent intradialytic complications while optimizing long-term outcomes. 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here. 🔹Transcript and Shownotes: 02: 19 | Pearl 1: Blood Pressure Targets 09: 40 | Pearl 2: Timing Medications and Dialyzability 15: 31 | Pearl 3 - Pharmacologic Management Nuances in Dialysis Patients 22: 57 | Putting It All Together: The Medication Hierarchy Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, ESRD, End-Stage Kidney Disease, Hypertension, Kidney Health, Dry Weight, Volume OverloadFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hypertension, drives many complications. Learn practical pearls on dry weight, sodium restriction, diuretics, and the strategies that can reduce hospitalizations and improve patient outcomes. 🔹Sponsor: Oakstone CMEUse the code "CORE325" for 25% off: https://www.coreimpodcast.com/MKSAP 🔹Transcript and Shownotes: 02:49 | Pearl 1: Foundations of Dialysis09:21 | Pearl 2: Distinct Physiology11:42 | Pearl 3: Why is fluid management so important?19:43 | Pearl 4: Fluid Management Pro-tips25:31 | Pearl 5: Diuretics in Patients with Residual Kidney FunctionTags: CoreIM, Internal Medicine, Medical Education, Nephrology, Dialysis, End-stage kidney disease, Hypertension, Kidney Health, Dry Weight, Volume OverloadFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clinical context still matters. When evidence is incomplete, and every patient is different, can AI truly practice medicine or only assist the clinicians who do? This episode explores the space between algorithms, uncertainty, and human judgment in modern medical care. 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to get home delivery (often same-day). Learn more here.🔹Transcript and Shownotes: 02:51 | Broad workup for reversible causes and other etiologies of AFib that may occur post-op05:10 | Considerations for management of post-op atrial fibrillation13:00 | Stroke risk in atrial fibrillation20:49 | Outpatient management of atrial fibrillation 25:54 | The role of AI in medical decision-makingTags: CoreIM, Internal Medicine, Medical Education, Atrial Fibrillation, Cardiology, Open EvidenceFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how ground medical support works, altitude physiology, legal protections, and how to stay calm when medicine suddenly happens at 35,000 feet. By the end, you may still sweat a little…but hopefully less than before.🔹Sponsor: Oakstone CMEUse the code "CORE325" for 25% off: https://www.coreimpodcast.com/MKSAP 🔹Transcript and Shownotes: 04:40 | Emergency Medical Kit (EMK) Standard Contents08:50 | Role of Ground-Based Medical Support & Flight Diversion Decision-Making19:35 | Interpreting Hypoxia at Altitude22:06 | In-Flight Liability23:35 | Common Chief Concerns & Useful Additional Medications24:53 | How to Be Resourceful in an Austere EnvironmentTags: CoreIM, Internal Medicine, Medical Education, In-flight Care, Medical Emergencies, Clinical Reasoning, Seizure Management, Hypoxia, Airway Management, Cardiac Emergency, Syncope, Respiratory DistressFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside?In this high-yield episode, test your clinical reasoning as we tackle:When eosinophilia becomes dangerous and why it mattersHow to distinguish if its from atopy vs. systemic diseaseWhich medications to stop (and which to watch)How travel, diet, and exposure history shape your workupWhen to suspect malignancy before giving steroids🔹Transcript and Shownotes: 02:34 | Why Do We Care About Eosinophilia? (Pearl 1)10:24 | Atopy and Eosinophilia (Pearl 2)18:57 | Drugs and Eosinophilia (Pearl 3)27:29 | ID and Eosinophilia (Pearl 4)33:54 | Pearl 5: Eosinophilia, Steroids, and Neoplasms (Pearl 5)Tags: CoreIM, Internal Medicine, Medical Education, Eosinophilia, Hypereosinophilia, Allergy Immunology, Hematology, Pulmonology, Parasitic Infections, AtopyFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Is coffee helping or harming our patients’ hearts?In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question:How should clinicians interpret nutrition research, especially when it feels inconsistent or hard to trust?Listen for a concise, practical framework you can use the next time a patient asks about coffee, diet, or lifestyle.🔹Sponsor: Oakstone CMEUse the code "CORE325" for 25% off: https://www.coreimpodcast.com/MKSAP 🔹 Transcript and Show notes00:00 | Challenges of interpreting nutritional research.02:22 | Best practices for evaluating studies in nutrition. 12:35 | Delve into the CRAVE trial as an example of critically appraising nutritional investigations.26:41 | Applying this to clinical practice for your patients.Tags: IMCore, Internal Medicine, Medical Education, Epidemiology, Diet and LifestyleFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students, residents, and clinicians who want a clear, usable approach..🔹Sponsor: DoxGPT by Doximity - an AI assistant built with practicing clinicians to deliver bottom-line clinical answers, chart summaries, secure calls, and faxing directly inside the Doximity app. See how fast it is and how easy to read at DoxGPT.com🔹Transcript and Shownotes:02:15 | Pearl 1: Pathophysiology08:20 | Pearl 2: Diagnosis16:35 | Pearl 3: Treatment20:35 | Pearl 4: Antibiotics27:39 | Pearl 5: Wound CareTags: CoreIM, Internal Medicine, Medical Education, Diabetic Foot Infections, Osteomyelitis, Foot Ulcer, Wound CareFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded?A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI?A patient arrives in the ED with uremic symptoms and a newly created AV fistula. Can you safely use it, or do you need to place a temporary dialysis catheter?And the classic inpatient dilemma: your heart failure patient looks better after diuresis, but the creatinine is rising. Is it time to stop, or should you keep going?🔹Sponsor: Pain Management and Opioids Adaptive Learning Free Online Course by NEJM Group: https://cme-info.nejm.org/core-im/See here for Neph Madness details See here for the POCUS region of NephMaddnessVOTE here to build your bracket!🔹Transcript and Shownotes:00:52 | What is NephMadness?02:19 | Detecting post-renal obstruction in a patient who reported normal urination11:26 | POCUS for discharge or continue diurese 17:25 | Distinguishing COPD from volume overload in a dialysis patient using lung ultrasound23:55 | Assessing AV fistula maturity at the bedside to potentially avoid placing a temporary dialysis lineAlong the way, we discuss practical ways clinicians can use renal, lung, and venous ultrasound to clarify uncertain clinical situations and make faster decisions at the bedside.If you’ve ever paused on rounds, wondering “what should we do next?” in a patient with kidney disease, this episode explores how POCUS can help answer that question.Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, AKI Management, POCUSFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them.• Do cholinesterase inhibitors really work?• What should clinicians know about lecanemab and donanemab before referring patients?• How much benefit should we expect and for how long?• When should you deprescribe dementia medications?🔹Sponsor: Caraway’s cookware set is a favorite for a reason.For 10% off, go to Carawayhome.com/CoreIM or use code CoreIM at checkout.🔹Transcript and Shownotes02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia?09:41 | Deep Dive 2: Prescribing medications for cognitive decline29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline35:46 | Deep Dive 4: Planning for an uncertain futureTags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistantFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Cognitive decline is tough for all parties. What are the high-yield questions to ask? What should you add to your one-liner? When do you stop using MOCA and try to clearly describe their functional status? Do all patients with cognitive decline need an MRI?🔹Sponsor: DoxGPT by Doximity - an AI assistant built with practicing clinicians to deliver bottom-line clinical answers, chart summaries, secure calls, and faxing directly inside the Doximity app. See how fast it is and how easy to read at DoxGPT.com🔹Transcript & Shownotes:01:12 | Cognitive Concerns During a Routine Follow-Up03:41 | Deep Dive 1: How do you pivot when you recognize unexpected memory issues?15:08 | Deep Dive 2: What tools should we use to characterize and stage cognitive decline?31:09 | Deep Dive 3: How do we determine the etiology of cognitive decline?Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistantFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy